18 research outputs found
Comparative effects of different dietary approaches on blood pressure in hypertensive and pre-hypertensive patients: A systematic review and network meta-analysis
Pairwise meta-analyses have shown beneficial effects of individual dietary approaches on blood
pressure but their comparative effects have not been established. Objective: Therefore we performed a
systematic review of different dietary intervention trials and estimated the aggregate blood pressure effects
through network meta-analysis including hypertensive and pre-hypertensive patients. Design: PubMed,
Cochrane CENTRAL, and Google Scholar were searched until June 2017. The inclusion criteria were defined as
follows: i) Randomized trial with a dietary approach; ii) hypertensive and pre-hypertensive adult patients; and iii)
minimum intervention period of 12 weeks. In order to determine the pooled effect of each intervention relative
to each of the other intervention for both diastolic and systolic blood pressure (SBP and DBP), random effects
network meta-analysis was performed. Results: A total of 67 trials comparing 13 dietary approaches (DASH, lowfat, moderate-carbohydrate, high-protein, low-carbohydrate, Mediterranean, Palaeolithic, vegetarian, low-GI/GL,
low-sodium, Nordic, Tibetan, and control) enrolling 17,230 participants were included. In the network metaanalysis, the DASH, Mediterranean, low-carbohydrate, Palaeolithic, high-protein, low-glycaemic index, lowsodium, and low-fat dietary approaches were significantly more effective in reducing SBP (¡8.73 to
¡2.32 mmHg) and DBP (¡4.85 to ¡1.27 mmHg) compared to a control diet. According to the SUCRAs, the DASH
diet was ranked the most effective dietary approach in reducing SBP (90%) and DBP (91%), followed by the
Palaeolithic, and the low-carbohydrate diet (ranked 3rd for SBP) or the Mediterranean diet (ranked 3rd for DBP).
For most comparisons, the credibility of evidence was rated very low to moderate, with the exception for the
DASH vs. the low-fat dietary approach for which the quality of evidence was rated high. Conclusion: The present network meta-analysis suggests that the DASH dietary approach might be the most effective dietary measure toreduce blood pressure among hypertensive and pre-hypertensive patients based on high quality evidence
Comparison of long-term low-fat versus high-fat diets on blood lipids: a systematic review and meta-analysis
Comparative effects of different dietary approaches on blood pressure in hypertensive and pre-hypertensive patients: A systematic review and network meta-analysis
Pairwise meta-analyses have shown beneficial effects of individual dietary approaches on blood
pressure but their comparative effects have not been established. Objective: Therefore we performed a
systematic review of different dietary intervention trials and estimated the aggregate blood pressure effects
through network meta-analysis including hypertensive and pre-hypertensive patients. Design: PubMed,
Cochrane CENTRAL, and Google Scholar were searched until June 2017. The inclusion criteria were defined as
follows: i) Randomized trial with a dietary approach; ii) hypertensive and pre-hypertensive adult patients; and iii)
minimum intervention period of 12 weeks. In order to determine the pooled effect of each intervention relative
to each of the other intervention for both diastolic and systolic blood pressure (SBP and DBP), random effects
network meta-analysis was performed. Results: A total of 67 trials comparing 13 dietary approaches (DASH, lowfat, moderate-carbohydrate, high-protein, low-carbohydrate, Mediterranean, Palaeolithic, vegetarian, low-GI/GL,
low-sodium, Nordic, Tibetan, and control) enrolling 17,230 participants were included. In the network metaanalysis, the DASH, Mediterranean, low-carbohydrate, Palaeolithic, high-protein, low-glycaemic index, lowsodium, and low-fat dietary approaches were significantly more effective in reducing SBP (¡8.73 to
¡2.32 mmHg) and DBP (¡4.85 to ¡1.27 mmHg) compared to a control diet. According to the SUCRAs, the DASH
diet was ranked the most effective dietary approach in reducing SBP (90%) and DBP (91%), followed by the
Palaeolithic, and the low-carbohydrate diet (ranked 3rd for SBP) or the Mediterranean diet (ranked 3rd for DBP).
For most comparisons, the credibility of evidence was rated very low to moderate, with the exception for the
DASH vs. the low-fat dietary approach for which the quality of evidence was rated high. Conclusion: The present network meta-analysis suggests that the DASH dietary approach might be the most effective dietary measure toreduce blood pressure among hypertensive and pre-hypertensive patients based on high quality evidence
A network meta-analysis on the comparative efficacy of different dietary approaches on glycaemic control in patients with type 2 diabetes mellitus
Food groups and risk of type 2 diabetes mellitus: a systematic review and meta-analysis of prospective studies
Mediterranean dietary pattern, inflammation and endothelial function: A systematic review and meta-analysis of intervention trials
Comparison of High vs. Normal/Low Protein Diets on Renal Function in Subjects without Chronic Kidney Disease: A Systematic Review and Meta-Analysis
An updated systematic review and meta-analysis on adherence to mediterranean diet and risk of cancer
Olive oil in the prevention and management of type 2 diabetes mellitus: a systematic review and meta-analysis of cohort studies and intervention trials
Background/Objectives: Olive oil (OO) as food is composed mainly of fatty acids and bioactive compounds depending from the extraction method. Both had been discussed as health promoting with still open questions. Thus, we conducted a meta-analysis to illustrate the impact of this food on type 2 diabetes (T2D) by investigating the association between OO intake and risk of T2D, and the effect of OO intake in the management of T2D.
Subjects/Methods: Searches were performed in PubMed, Cochrane Library and google scholar. First, we conducted a random effect meta-analysis of prospective cohort studies and trials investigating the association between OO and risk of T2D. Second, a meta-analysis was performed to detect the effects of olive oil on glycemic control in patients with T2D.
Results: Four cohort studies including 15 784 T2D cases and 29 trials were included in the meta-analysis. The highest OO intake category showed a 16% reduced risk of T2D (RR: 0.84; 95% CI: 0.77, 0.92) compared with the lowest. However, we observed evidence for a nonlinear relationship. In T2D patients OO supplementation resulted in a significantly more pronounced reduction in HbA1c (MD: −0.27%; 95% CI: −0.37, −0.17) and fasting plasma glucose (MD: −0.44 mmol l−1; 95% CI −0.66, −0.22) as compared with the control groups.
Conclusions: This meta-analysis provides evidence that the intake of OO could be beneficial for the prevention and management of T2D. This conclusion regards OO as food, and might not been valid for single components comprising this food.© The Author(s) 201