Stringent upper limit on the direct 3α decay of the Hoyle state in 12C

We investigate an implication of the most recent observation of a second Jπ=2+ state in 12C, which was measured using the 12C(γ,α)8Be(g.s.) reaction. In addition to the dissociation of 12C to an α-particle and 8Be in its ground state, a small fraction of events (2%) were identified as direct decays and decays to excited states in 8Be. This allowed a limit on the direct 3α partial decay width to be determined as Γ3α<32(4) keV. Since this 2+ state is predicted by all theoretical models to be a collective excitation of the Hoyle state, the 3α partial width of the Hoyle state is calculable from the ratio of 3α decay penetrabilities of the Hoyle and 2+ states. This was calculated by using the semiclassical Wenzel-Kramers-Brillouin approach and we deduce a stringent upper limit for the direct decay branching ratio of the Hoyle state of Γ3α Γ <5.7×10−6, over an order of magnitude lower than previously reported. This result places the direct measurement of this rare decay mode beyond current experimental capabilities

Select environmental and genetic determinants of adiponectin and obesity in black and white women

Using interview data and blood samples collected at baseline from the Southern Community Cohort Study, this cross-sectional study examined serum adiponectin levels in relation to select environmental and behavioral factors. Several single nucleotide polymorphisms (SNPs) in three adiponectin-related genes (ADIPOQ, ADIPOR1, and ADIPOR2) were also examined in relation to adiponectin and body mass index (BMI). Multivariate linear regression models were used to evaluate the association between adiponectin and BMI separately for white and black women. Prediction models for adiponectin for black and white women were also developed using multiple linear regression. Associations between SNPs in ADIPOQ, ADIPOR1, and ADIPOR2 in relation to adiponectin and BMI were examined in linear regression models with adjustment for age and percentage of African ancestry to account for population stratification. Black women were found to have lower adiponectin levels compared with whites even after adjustment for body mass index (BMI). These results expand upon previous studies that were limited by small sample sizes or narrow age and body size ranges and demonstrate that racial differences in adiponectin exist across the spectrum of BMI. In the examination of predictors of adiponectin beyond BMI, the factors age, HDL-cholesterol, and hypertension were found to be strong correlates of adiponectin in both race groups. In the genetic analyses, one SNP (rs17366568) in ADIPOQ was found to be significantly associated with adiponectin in white women but not in black women. This finding confirms results from two recent genome-wide association studies in European whites by demonstrating significant differences in adiponectin levels across genotypes of SNP rs17366568 and expands the current literature by examining this SNP in black women for the first time. No significant associations were observed between any of the SNPs in the three adiponectin-related genes and BMI. Observed racial differences in adiponectin and its correlates from this study will be utilized in future studies of diseases potentially affected by adiponectin such as cancer, cardiovascular disease, and type 2 diabetes. In addition, the development of lifestyle interventions as well as therapeutics that increase adiponectin levels for the purpose of disease prevention may be guided by results of this study

Identification and Characterization of Mitogen-Activated Protein Kinase (MAPK) Genes in Sunflower (Helianthus annuus L.)

Mitogen-Activated Protein Kinase (MAPK) genes encode proteins that regulate biotic and abiotic stresses in plants through signaling cascades comprised of three major subfamilies: MAP Kinase (MPK), MAPK Kinase (MKK), and MAPKK Kinase (MKKK). The main objectives of this research were to conduct genome-wide identification of MAPK genes in Helianthus annuus and examine functional divergence of these genes in relation to those in nine other plant species (Amborella trichopoda, Aquilegia coerulea, Arabidopsis thaliana, Daucus carota, Glycine max, Oryza sativa, Solanum lycopersicum, Sphagnum fallax, and Vitis vinifera), representing diverse taxonomic groups of the Plant Kingdom. A Hidden Markov Model (HMM) profile of the MAPK genes utilized reference sequences from A. thaliana and G. max, yielding a total of 96 MPKs and 37 MKKs in the genomes of A. trichopoda, A. coerulea, C. reinhardtii, D. carota, H. annuus, S. lycopersicum, and S. fallax. Among them, 28 MPKs and eight MKKs were confirmed in H. annuus. Phylogenetic analyses revealed four clades within each subfamily. Transcriptomic analyses showed that at least 19 HaMPK and seven HaMKK genes were induced in response to salicylic acid (SA), sodium chloride (NaCl), and polyethylene glycol (Peg) in leaves and roots. Of the seven published sunflower microRNAs, five microRNA families are involved in targeting eight MPKs. Additionally, we discussed the need for using MAP Kinase nomenclature guidelines across plant species. Our identification and characterization of MAP Kinase genes would have implications in sunflower crop improvement, and in advancing our knowledge of the diversity and evolution of MAPK genes in the Plant Kingdom

Cancer mortality in a Texas county with prior uranium mining and milling activities, 1950-2001

Abstract Uranium was discovered in Karnes County, Texas, in 1954 and the first uranium mill began operating in 1961 near Falls City. Uranium milling and surface and in situ mining continued in Karnes County until the early 1990s. Remediation of uranium tailings ponds was completed in the 1990s. There were three mills and over 40 mines operating in Karnes County over these years and potential exposure to the population was from possible environmental releases into the air and ground water. From time to time concerns have been raised in Karnes County about potential increased cancer risk from these uranium mining and milling activities. To evaluate the possibility of increased cancer deaths associated with these uranium operations, a mortality survey was conducted. The numbers and rates of cancer deaths were determined for Karnes County and for comparison for four &apos;control&apos; counties in the same region with similar age, race, urbanisation and socioeconomic distributions reported in the 1990 US Census. Comparisons were also made with US and Texas general population rates. Following similar methods to those used by the National Cancer Institute, standardised mortality ratios (SMRs) were computed as the ratio of observed numbers of cancers in the study and control counties compared to the expected number derived from general population rates for the United States. Relative risks (RRs) were computed as the ratios of the SMRs for the study and the control counties. Overall, 1223 cancer deaths occurred in the population residing in Karnes County from 1950 to 2001 compared with 1392 expected based on general population rates for the US. There were 3857 cancer deaths in the four control counties during the same 52 year period compared with 4389 expected. There was no difference between the total cancer mortality rates in 3 Author to whom any correspondence should be addressed. Karnes County and those in the control counties (RR = 1.0; 95% confidence interval 0.9-1.1). There were no significant increases in Karnes County for any cancer when comparisons were made with either the US population, the State of Texas or the control counties. In particular, deaths due to cancers of the lung, bone, liver and kidney were not more frequent in Karnes County than in the control counties. These are the cancers of a priori interest given that uranium might be expected to concentrate more in these tissues than in others. Further, any radium intake would deposit primarily in the bone and radon progeny primarily in the lung. Deaths from all cancers combined also were not increased in Karnes County and the RRs of cancer mortality in Karnes County before and in the early years of operations , shortly after the uranium activities began and in two later time periods (1990)(1991)(1992)(1993)(1994)(1995)(1996)(1997)(1998)(1999)(2000)(2001) were similar, 1.0, 0.9, 1.1 and 1.0, respectively. No unusual patterns of cancer mortality could be seen in Karnes County over a period of 50 years, suggesting that the uranium mining and milling operations had not increased cancer rates among residents

Aims and challenges of building national trainee networks in clinical microbiology and infectious disease disciplines

Trainees represent the medical practice of tomorrow. Interactions and collaborations at the early stage in career will strengthen the future of our specialties, clinical microbiology and infectious diseases. Trainee networks at the national level help access the best education and career opportunities. The aim of this collaborative white paper between the Trainee Association of European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and four national trainee networks is to discuss the motivation for building such networks and offer guidance for their creation and sustainability even during a health crisis.Publisher PDFPeer reviewe

The Ursinus Weekly, April 23, 1951

Students elect Hartzel, Hall, Ely, Landis: Women\u27s government, YM-YWCA, WAA choose new organization heads • Drs. Armstrong, Mattern, Baker to be speakers • Pa. Dutch film scheduled for benefit show • Nancy Bare and Jackie Keller to share big Arsenic role • Six juniors receive Cub and Key memberships for outstanding work • Lantern deadline set for Friday • Barbara Crawford crowned queen of Junior Prom; 4 attendants named • Editorials: Nominations open; Voting results analyzed • French situation reversed • Truman vs MacArthur • Letters to the editor • Weekly back issues yield untold wealth of pertinent advertisements • Recordak machine aids in library efficiency • Posting of exams recalls looming fate of students • Baseball field dedicated in honor of Dr. John Price • Girls\u27 tennis team downs Swarthmore for second victory • Curtis takes lead in intramural loop • Netmen lose opener to Haverford; Girls triumph over Chestnut Hill, 4-1 • Bears defeat Pharmacy to gain initial triumph, 14-5 • Bears defeat Haverford for second victory, 7-5 • Tennis team wins first court game • Cumpstone breaks own javelin mark as Grizzlies lose • Curtain Club levies charge for using stage materials • Freshmen, Sophs announce picnic at Island Grove • Blood donors must register, get permission if under-age • Dr. Phillips reads unknown Kipling short story to group • Curtain Club to elect • Varsity Club show ready for production Friday night • Red Cross to sponsor water safety instructor\u27s course • Seniors plan picnic • French Club gives recital featuring pianists, vocalists • Newman Club film slated • Nels Fellman elected head of Delta Pi Sigma frathttps://digitalcommons.ursinus.edu/weekly/1566/thumbnail.jp

The New Generation Atlas of Quasar Spectral Energy Distributions from Radio to X-rays

We have produced the next generation of quasar spectral energy distributions (SEDs), essentially updating the work of Elvis et al. (1994) by using high-quality data obtained with several space and ground-based telescopes, including NASA's Great Observatories. We present an atlas of SEDs of 85 optically bright, non-blazar quasars over the electromagnetic spectrum from radio to X-rays. The heterogeneous sample includes 27 radio-quiet and 58 radio-loud quasars. Most objects have quasi-simultaneous ultraviolet-optical spectroscopic data, supplemented with some far-ultraviolet spectra, and more than half also have Spitzer mid-infrared IRS spectra. The X-ray spectral parameters are collected from the literature where available. The radio, far-infrared, and near-infrared photometric data are also obtained from either the literature or new observations. We construct composite spectral energy distributions for radio-loud and radio-quiet objects and compare these to those of Elvis et al., finding that ours have similar overall shapes, but our improved spectral resolution reveals more detailed features, especially in the mid and near-infrared.Comment: 46 pages, 10 figures, 10 tables, Accepted by ApJS. Composite SED data files for radio-loud and radio-quiet quasars (rlmsedMR.txt, rqmsedMR.txt) are included in the source (Other formats -> Source). Supplemental figures are not include