Nurses\u27 Alumnae Association Bulletin, June 1970

Alumnae President\u27s Message Congratulations Alumni Association Portrait of Samuel D. Gross Officers and Chairmen of Committees Financial Report Progress of Jefferson 1969-1970 School of Nursing Annual Report School of Practical Nursing Report Emergency Department Patient Services Department Annual Luncheon Pictures Committee Reports Progress of the Alumnae Association Crossword Puzzle Missing Graduates Resume of Alumnae Meetings Minutes Class News Student Nurses Section Crossword Puzzle Answers Notice

Analysis of Epithelial Growth Factor-Receptor (EGFR) Phosphorylation in Uterine Smooth Muscle Tumors

Uterine fibroids are the commonest uterine benign tumors. A potential mechanism of malignant transformation from leiomyomas to leiomyosarcomas has beendescribed. Tyrosine phosphorylation is a key mechanism that controls biological functions, such as proliferation and cell differentiation. The aim of the current study was to evaluate the phosphorylation of epithelial growth factor-receptor (EGFR) in normal myometrium, uterine myomas and uterine leiomyosarcomas. Formalin-fixed paraffin-embedded tissue samples from normal myometrium, leiomyomas and leiomyosarcomas were studied. Samples were immunohistochemically (IHC) assessed using the anti-EGFR phosphorylation of Y845 (pEGFR-Y845) and anti-pEGFR-Y1173 phosphorylation-specific antibodies. IHC staining was evaluated using a semiquantitative score. The expression of pEGFR-Y845 was significantly upregulated in leiomyosarcomas (p < 0.001) compared to leiomyomas and normal myometrium. In contrast, pEGFR-Y1173 did not differ significantly between the three groups of the study. Correlation analysis revealed an overall positive correlation between pEGFR Y845 and mucin 1 (MUC1). Further subgroup analysis within the tumoral group (myomas and leiomyosarcomas) revealed an additional negative correlation between pEGFR Y845 and galectin-3 (gal-3) staining. On the contrary no significant correlation was noted within the non-tumoral group. An upregulated EGFR phosphorylation of Y845 in leiomyosarcomas compared to leiomyomas implicates EGFR activation at this special receptor site. Due to these pEGFR-Y845 variations, it can be postulated that MUC1 interacts with it, whereas gal-3 seems to be cleaved from Y845 phosphorylated EGFR. Further research on this field could focus on differences in EGFR pathways as a potentially advantageous diagnostic tool for investigation of benign and malignant signal transduction processes

Evaluation of chicken manure compost in the yield and nutritional quality of alfalfa in the central highlands of Peru

Se evaluó el efecto del uso de compost de guano de pollos (CGP) en niveles de (T1) 0, (T2) 10 y (T3) 20 t/ha sobre el rendimiento de forraje verde (FV), materia seca (MS), altura de planta (AP) y proteína total (PT) de la alfalfa en una pradera de Huancayo (Junín, Perú). El abonamiento se hizo al primer día del estudio y al inicio de la semana 6. El primer corte se hizo a los 42 días del primer abonamiento y el segundo corte a los 35 días del segundo abonamiento. Los rendimientos al segundo corte de FV en T1, T2 y T3 fueron de 18.6, 23.5 y 26.8 t/ha (p&lt;0.05), de MS de 2.5, 7.0 y 7.1 t/ha (p&lt;0.05), de PT de 0.8, 1.0 y 1.2 t/ha (p&lt;0.05) y de AP de 60.8, 66.9 y 63.8 cm, respectivamente (p&lt;0.05). Se demuestra que es posible emplear compost de guano de pollos broiler para obtener una mayor producción orgánica de alfalfa.The effect of using chicken manure compost (CGP) at levels of (T1) 0, (T2) 10 and (T3) 20 t/ha, on green forage yield (GF), dry matter (DM), plant height (PH) and total protein (TP) of alfalfa, in a pasture area of Huancayo (Junín, Peru) was evaluated. The fertilization was done on the first day of the study and at the beginning of week 6. The first cut was done at 42 days of the first fertilization and the second at 35 days of the second fertilization. The yields at the second cut of GF in T1, T2 and T3 were 18.6, 23.5 and 26.8 t/ha (p&lt;0.05), of DM were 2.5, 7.0 and 7.1 t/ha (p&lt;0.05), of TP were 0.8, 1.0 and 1.2 t/ha (p&lt;0.05) and of PH were 60.8, 66.9 and 63.8 cm, respectively (p&lt;0.05). It was shown that it is possible to use broiler chicken manure compost to obtain an improved organic alfalfa production

Alumnae Association Bulletin of the School of Nursing, 1973

Alumnae Calendar The President\u27s Message Officers and Chairmen of Committees Financial Report Annual Reports Named to Academy of Nursing Alumnae Association Relief Fund Benefits Sesquicentennial - A Celebration and a Challenge Progress of the Thomas Jefferson University Hospital 1972-1973 Report of the Patient Services Department Changes in the Department of Radiation Therapy Annual Luncheon Committee Reports Administration Missing Alumnae Members Salute to Life Members The Class of 1973 Ways and Means Committee Report Resume of Minutes of Alumnae Association Meetings Class Notes Marriages Births In Memoriam Notice

Chemoprophylaxis and Malaria Death Rates

Malaria chemoprophylaxis increases the survival of nonimmune travelers

Research ethics governance in times of Ebola.

CAPRISA, 2017.Abstract available in pdf

The Changing of the Guard: The New American Labor Leader

This article analyzes recent changes in the leadership of international unions. There has been a trend toward leaders who are lifetime bureaucrats rather than rank-and-file members with charisma. This change toward more technocratic leadership is due to the different environment and new challenges that labor currently faces. The United Mine Workers is a good example of a union that has had many changes in the type of person who has become president, from the labor giant John L. Lewis to the 33-year-old lawyer Richard Trumka. The United Auto Workers is an example of a union whose leadership has been consistently drawn from the union hierarchy. The AFL-CIO has made a change in leadership from George Meany to the labor bureaucrat Lane Kirkland. There will probably be an increase in the number of women and minorities in top leadership positions in unions, but this will be a gradual increase.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/66627/2/10.1177_000271628447300107.pd

Multimodal Communication in a Noisy Environment: A Case Study of the Bornean Rock Frog Staurois parvus

High background noise is an impediment to signal detection and perception. We report the use of multiple solutions to improve signal perception in the acoustic and visual modality by the Bornean rock frog, Staurois parvus. We discovered that vocal communication was not impaired by continuous abiotic background noise characterised by fast-flowing water. Males modified amplitude, pitch, repetition rate and duration of notes within their advertisement call. The difference in sound pressure between advertisement calls and background noise at the call dominant frequency of 5578 Hz was 8 dB, a difference sufficient for receiver detection. In addition, males used several visual signals to communicate with conspecifics with foot flagging and foot flashing being the most common and conspicuous visual displays, followed by arm waving, upright posture, crouching, and an open-mouth display. We used acoustic playback experiments to test the efficacy-based alerting signal hypothesis of multimodal communication. In support of the alerting hypothesis, we found that acoustic signals and foot flagging are functionally linked with advertisement calling preceding foot flagging. We conclude that S. parvus has solved the problem of continuous broadband low-frequency noise by both modifying its advertisement call in multiple ways and by using numerous visual signals. This is the first example of a frog using multiple acoustic and visual solutions to communicate in an environment characterised by continuous noise