Executive Dismissal or Retention? A Study of Performance, Power, and Survival for College Basketball Coaches

This study applies upper echelons theory associated with executive dismissal and power to examine the relationships of performance and four types of executive power—structural, prestige, expert, and governance concentration—with dismissal. Using the context of National Collegiate Athletic Association college basketball, in which coaches are completely responsible for strategies and human capital acquisition and retention, a curvilinear relationship between performance and dismissal is found. Significant relationships for prestige and expert power with dismissal are also found, but the “honeymoon period” is longer than prior studies of executive and coach dismissal have shown. Surprisingly, concentrated governance is found to be negatively associated with the likelihood of dismissal

Adenovirus E4orf4 Induces HPV-16 Late L1 mRNA Production

The adenovirus E4orf4 protein regulates the switch from early to late gene expression during the adenoviral replication cycle. Here we report that overexpression of adenovirus E4orf4 induces human papillomavirus type 16 (HPV-16) late gene expression from subgenomic expression plasmids. E4orf4 specifically overcomes the negative effects of two splicing silencers at the two late HPV-16 splice sites SD3632 and SA5639. This results in the production of HPV-16 spliced L1 mRNAs. We show that the interaction of E4orf4 with protein phosphatase 2A (PP2A) is necessary for induction of HPV-16 late gene expression. Also an E4orf4 mutant that fails to bind the cellular splicing factor ASF/SF2 fails to induce L1 mRNA production. Collectively, these results suggest that dephosphorylation of SR proteins by E4orf4 activates HPV-16 late gene expression. Indeed, a mutant ASF/SF2 protein in which the RS-domain had been deleted could itself induce HPV-16 late gene expression, whereas wild type ASF/SF2 could not

A Descriptive Profile of Physical Education Teachers and Related Program Characteristics in Alberta

A survey of teachers and principals in Alberta was conducted to gain a descriptive profile of who is leaching physical education (PE) and to assess the relationship between PE specialists and variables associated with program delivery. A probability-sampling procedure was used to obtain a representative sample of schools. In these schools nonprobability procedures were used to recruit teachers. A total of'480 teachers' and 162 principals' questionnaires were returned. Although 50% (n=236) of PE teachers in the sample were classified as PE specialists (i.e., had either a degree, major or minor, in PE or a closely related area), there was a significant gap in the number of PE classes being taught by division. Of the 1,219 PE classes surveyed in this study, PE specialists taught 49% and 55% of classes at the elementary levels (Divisions I & 11) compared with 91% of junior high (Division III) and 90% of secondary (Division TV) PE classes. Significant differences were found between PE specialists and non-PE specialists on a number of items including perceptions of preparedness, teaching enjoyment and competence to teach PE, the number of PE specialists across grade levels, and the percentage of time devoted to PE in the timetable. Implications with respect to implementing PE specialists across all grades and the need for future pedagogical research to investigate the effect of PE specialists are also discussed.Une enquête a été entreprise auprès d'enseignants et de directeurs d'école en Alberta dans le but d'établir un profil descriptif des enseignants d'éducation physique (EP) et d'évaluer le rapport entre les spécialistes en EP et les variables associées à l'exécution de programmes. On a eu recours aune méthode d'échantillonnage au hasard pour obtenir un échantillon représentatif des écoles. Par la suite, on y a employé des procédures non probabilistes pour recruter des enseignants. En tout, 642 questionnaires (480 provenant d'enseignants et 162 de directeurs) nous ont été renvoyés. Alors que 50% (n=236) des enseignants de EP de l'échantillon se classaient comme spécialistes en EP (c'est-à-dire qu'ils avaient soit un diplôme, une majeure ou une mineure en EP ou dans un domaine connexe), un écart notable existait dans le nombre de cours de EP enseignés par division. Des 1 219 cours de EP inclus dans l'enquête, à l'élémentaire, 49% (Division I) et 55% (Division II) d'entre eux étaient enseignés par des spécialistes en EP. Au secondaire premier cycle (Division III), 91% des cours étaient enseignés par des spécialistes en EP; au secondaire (Division IV), 90% des cours l'étaient. Des différences importantes distinguaient les spécialistes en EP des non spécialistes, y compris leurs perceptions quant à leur état de préparation, le plaisir qu'il retirait de l'enseignement de l'EP, leur compétence à le faire, le nombre de spécialistes en EP à tous les niveaux scolaires et le nombre d'heures consacrées aux cours de EP. Une discussion portant sur les implications de la mise en place de spécialistes en EP à tous les niveaux scolaires et sur la nécessité d'étudier l'effet qu'exercent ceux-ci, termine l'article

Fall Risk Factors for Community-Dwelling Older Adults: An Evidence-Based Practice Project

What are the descriptive or predictive characteristics of community-dwelling older adults who are most at risk for falls

The Shapiro Design Lab Residency

A publication documenting the inaugural year of the Shapiro Design Lab Residency.https://deepblue.lib.umich.edu/bitstream/2027.42/142813/1/DesignLabResidency_Publication.pdfDescription of DesignLabResidency_Publication.pdf : PDF of publicatio

Latent human traits in the language of social media: An open-vocabulary approach

Over the past century, personality theory and research has successfully identified core sets of characteristics that consistently describe and explain fundamental differences in the way people think, feel and behave. Such characteristics were derived through theory, dictionary analyses, and survey research using explicit self-reports. The availability of social media data spanning millions of users now makes it possible to automatically derive characteristics from behavioral data-language use-at large scale. Taking advantage of linguistic information available through Facebook, we study the process of inferring a new set of potential human traits based on unprompted language use. We subject these new traits to a comprehensive set of evaluations and compare them with a popular five factor model of personality. We find that our language-based trait construct is often more generalizable in that it often predicts non-questionnaire-based outcomes better than questionnaire-based traits (e.g. entities someone likes, income and intelligence quotient), while the factors remain nearly as stable as traditional factors. Our approach suggests a value in new constructs of personality derived from everyday human language use

Nurses\u27 Alumnae Association Bulletin, June 1970

Alumnae President\u27s Message Congratulations Alumni Association Portrait of Samuel D. Gross Officers and Chairmen of Committees Financial Report Progress of Jefferson 1969-1970 School of Nursing Annual Report School of Practical Nursing Report Emergency Department Patient Services Department Annual Luncheon Pictures Committee Reports Progress of the Alumnae Association Crossword Puzzle Missing Graduates Resume of Alumnae Meetings Minutes Class News Student Nurses Section Crossword Puzzle Answers Notice

Erratum to: Benchmarks for ethically credible partnerships between industry and academic health centers: beyond disclosure of financial conflicts of interest.

Relationships between industry and university-based researchers have been commonplace for decades and have received notable attention concerning the conflicts of interest these relationships may harbor. While new efforts are being made to update conflict of interest policies and make industry relationships with academia more transparent, the development of broader institutional partnerships between industry and academic health centers challenges the efficacy of current policy to effectively manage these innovative partnerships. In this paper, we argue that existing strategies to reduce conflicts of interest are not sufficient to address the emerging models of industry-academic partnerships because they focus too narrowly on financial matters and are not comprehensive enough to mitigate all ethical risk. Moreover, conflict-of-interest strategies are not designed to promote best practices nor the scientific and social benefits of academic-industry collaboration. We propose a framework of principles and benchmarks for "ethically credible partnerships" between industry and academic health centers and describe how this framework may provide a practical and comprehensive approach for designing and evaluating such partnerships

Regulated Formation of an Amyloid-like Translational Repressor Governs Gametogenesis

Message-specific translational control is required for gametogenesis. In yeast, the RNA-binding protein Rim4 mediates translational repression of numerous mRNAs, including the B-type cyclin CLB3, which is essential for establishing the meiotic chromosome segregation pattern. Here, we show that Rim4 forms amyloid-like aggregates and that it is the amyloid-like form of Rim4 that is the active, translationally repressive form of the protein. Our data further show that Rim4 aggregation is a developmentally regulated process. Starvation induces the conversion of monomeric Rim4 into amyloid-like aggregates, thereby activating the protein to bring about repression of translation. At the onset of meiosis II, Rim4 aggregates are abruptly degraded allowing translation to commence. Although amyloids are best known for their role in the etiology of diseases such as Alzheimer’s, Parkinson’s, and diabetes by forming toxic protein aggregates, our findings show that cells can utilize amyloid-like protein aggregates to function as central regulators of gametogenesis.Charles A. King Trust (Postdoctoral Fellowship)American Cancer Society (Fellowship)National Institutes of Health (U.S.) (Grants GM62207, GM77537, and GM094303