168 research outputs found
The Life-Cycle Hypothesis Revisited: Evidence on Housing Consumption after Retirement
According to the life-cycle theory of consumption and saving, foreseeable retirement events should not reduce consumption. Whereas some consumption expenditures may fall when they are self-produced (given higher leisure after retirement), this argument applies especially to housing consumption which can hardly be substituted by home production. We test this hypothesis using micro data for Germany (GSOEP) and find that income reductions when entering retirement have a negative effect on housing expenditures for tenants. For some econometric specifications, this effect is significantly stronger than the one of income changes at other times. While this result suggests that the strict consumption-smoothing hypothesis is violated for the subgroup of nonhome owners, the effect is quantitatively small, which explains the ambiguity of previous findings.consumption smoothing, retirement-consumption puzzle, GSOEP
Using Provenance to support Good Laboratory Practice in Grid Environments
Conducting experiments and documenting results is daily business of
scientists. Good and traceable documentation enables other scientists to
confirm procedures and results for increased credibility. Documentation and
scientific conduct are regulated and termed as "good laboratory practice."
Laboratory notebooks are used to record each step in conducting an experiment
and processing data. Originally, these notebooks were paper based. Due to
computerised research systems, acquired data became more elaborate, thus
increasing the need for electronic notebooks with data storage, computational
features and reliable electronic documentation. As a new approach to this, a
scientific data management system (DataFinder) is enhanced with features for
traceable documentation. Provenance recording is used to meet requirements of
traceability, and this information can later be queried for further analysis.
DataFinder has further important features for scientific documentation: It
employs a heterogeneous and distributed data storage concept. This enables
access to different types of data storage systems (e. g. Grid data
infrastructure, file servers). In this chapter we describe a number of building
blocks that are available or close to finished development. These components
are intended for assembling an electronic laboratory notebook for use in Grid
environments, while retaining maximal flexibility on usage scenarios as well as
maximal compatibility overlap towards each other. Through the usage of such a
system, provenance can successfully be used to trace the scientific workflow of
preparation, execution, evaluation, interpretation and archiving of research
data. The reliability of research results increases and the research process
remains transparent to remote research partners.Comment: Book Chapter for "Data Provenance and Data Management for eScience,"
of Studies in Computational Intelligence series, Springer. 25 pages, 8
figure
New Evidence on the Life-Cycle Hypothesis
We revisit the alleged retirement consumption puzzle. According to the life-
cycle theory, foreseeable income reductions such as those around retirement
should not affect consumption. However, we first recall that given higher
leisure endowments after retirement, the theory does predict a fall of total
market consumption expenditures. In order not to mistake this predicted drop
for a puzzle we focus on housing consumption which can be plausibly regarded
as complementary to leisure, and we control for the leisure change in our
empirical specifications, using micro data for Germany (SOEP), where housing
expenditures are observable as rents for the majority (60%), as well as
dwelling relocations. We still find significant negative impacts of the
retirement status on housing consumption, which is hard to reconcile with the
life-cycle theory. For retirees we also find significant effects of the income
reduction at retirement on housing. However, the effects are small in
quantitative terms, given the lock-in nature of past housing decisions
Leisure and housing consumption after retirement: new evidence on the life-cycle hypothesis
Foreseeable income reductions around retirement should not affect aggregate consumption. However, given higher leisure endowments after retirement, theory also predicts lower consumption of leisure substitutes. To avoid misinterpreting this predicted drop as a puzzle, our novel approach focuses on housing consumption (complementary to leisure in utility) and controls for leisure changes. In Germany tenants represent roughly half of all households, making many housing expenditures directly observable in micro data. We find significant negative impacts of the retirement status on housing consumption, which is hard to reconcile with life-cycle theory. Despite the lock-in nature of past housing decisions, income reductions at retirement have additional â though small â effects on housing
GridScore:a tool for accurate, cross-platform phenotypic data collection and visualization
Background: Plant breeding and crop research rely on experimental phenotyping trials. These trials generate data for large numbers of traits and plant varieties that needs to be captured efficiently and accurately to support further research and downstream analysis. Traditionally scored by hand, phenotypic data is nowadays collected using spreadsheets or specialized apps. While many solutions exist, which increase efficiency and reduce errors, none offer the same familiarity as printed field plans which have been used for decades and offer an intuitive overview over the trial setup, previously recorded data and plots still requiring scoring.Results: We introduce GridScore which utilizes cutting-edge web technologies to reproduce the familiarity of printed field plans while enhancing the phenotypic data collection process by adding advanced features like georeferencing, image tagging and speech recognition. GridScore is a cross-platform open-source plant phenotyping app that combines barcode-based systems with a guided data collection approach while offering a top-down view onto the data collected in a field layout. GridScore is compared to existing tools across a wide spectrum of criteria including support for barcodes, multiple platforms, and visualizations.Conclusion: Compared to its competition, GridScore shows strong performance across the board offering a complete manual phenotyping experience.</p
Influence of Different Beam Energies on the Micro-Bunching Instability
During the operation of an electron synchrotron with short electron bunches, the beam dynamics are influenced by the occurrence of the micro-bunching instability. This collective instability is caused by the self-interaction of a short electron bunch with its own emitted coherent synchrotron radiation (CSR). Above a certain threshold bunch current dynamic micro-structures start to occur on the longitudinal phase space density. The resulting dynamics depend on various parameters and were previously investigated in relation to, amongst others, the momentum compaction factor and the acceleration voltage. In this contribution, the influence of the energy of the electrons on the dynamics of the micro-bunching instability is studied based on measurements at the KIT storage ring KARA (Karlsruhe Research Accelerator)
Major chromosome 5H haplotype switch structures the European two-rowed spring barley germplasm of the past 190Â years
Selection over 70 years has led to almost complete fixation of a haplotype spanning ~ 250 Mbp of chomosome 5H in European two-rowed spring barleys, possibly originating from North Africa. Plant breeding and selection have shaped the genetic composition of modern crops over the past decades and centuries and have led to great improvements in agronomic and quality traits. Knowledge of the genetic composition of breeding germplasm is essential to make informed decisions in breeding programs. In this study, we characterized the structure and composition of 209 barley cultivars representative of the European two-rowed spring barley germplasm of the past 190 years. Utilizing high-density SNP marker data, we identified a distinct centromeric haplotype spanning a ~ 250 Mbp large region on chromosome 5H which likely was first introduced into the European breeding germplasm in the early to mid-twentieth century and has been non-recombining and under strong positive selection over the past 70 years. Almost all cultivars in our panel that were released after 2000 carry this new haplotype, suggesting that this region carries one or several genes conferring highly beneficial traits. Using the global barley collection of the German Federal ex situ gene bank at IPK Gatersleben, we found the new haplotype at high frequencies in six-rowed spring-type landraces from Northern Africa, from which it may have been introduced into modern European barley germplasm via southern European landraces. The presence of a 250 Mbp genomic region characterized by lack of recombination and high levels of fixation in modern barley germplasm has substantial implications for the genetic diversity of the modern barley germplasm and for barley breeding
The proteome of developing barley anthers during meiotic prophase I
Flowering plants reproduce sexually by combining a haploid male and female gametophyte during fertilization. Male gametophytes are localized in the anthers, each containing reproductive (meiocyte) and non-reproductive tissue necessary for anther development and maturation. Meiosis, where chromosomes pair and exchange their genetic material during a process called recombination, is one of the most important and sensitive stages in breeding, ensuring genetic diversity. Most anther development studies have focused on transcript variation, but very few have been correlated with protein abundance. Taking advantage of a recently published barley anther transcriptomic (BAnTr) dataset and a newly developed sensitive mass spectrometry-based approach to analyse the barley anther proteome, we conducted high-resolution mass spectrometry analysis of barley anthers, collected at six time points and representing their development from pre-meiosis to metaphase. Each time point was carefully staged using immunocytology, providing a robust and accurate staging mirroring our previous BAnTr dataset. We identified >6100 non-redundant proteins including 82 known and putative meiotic proteins. Although the protein abundance was relatively stable throughout prophase I, we were able to quantify the dynamic variation of 336 proteins. We present the first quantitative comparative proteomics study of barley anther development during meiotic prophase I when the important process of homologous recombination is taking place.</p
Mode of Action of the Natural Product Allicin in a Plant Model:Influence on the Cytoskeleton and Subsequent Shift in Auxin Localization
Allicin is a defense substance produced by garlic cells when they are injured. It is a redox-active thiosulfinate showing redox-activity with a broad range of dose-dependent antimicrobial and biocidal activity. It is known that allicin efficiently oxidizes thiol-groups, and it has been described as a redox toxin because it alters the redox homeostasis in cells and triggers oxidative stress responses. Allicin can therefore be used as a model substance to investigate the action of thiol-specific prooxidants. In order to learn more about the effect of allicin on plants, we used pure synthetized allicin, and studied the influence of allicin on organelle movement in Tradescantia fluminensis as a cytoskeleton-dependent process. Furthermore, we investigated cytoplasmic streaming in sterile filaments of Tradescantia fluminensis, organelle movement using transgenic Arabidopsis with organelle-specifics GFP-tags, and effects on actin and tubulin in the cytoskeleton using GFP-tagged lines. Tubulin and actin were visualized by GFP-tagging in transgenic lines of Arabidopsis thaliana to visualize the influence of allicin on the cytoskeleton. Since auxin transport depends on recycling and turnover of the PIN protein involving cytoskeletal transport to and from the membrane localization sites, auxin distribution in roots was investigated using of transgenic PIN1âGFP, PIN3âGFP, DR5âGFP and DIIâVENUS Arabidopsis reporter lines. Allicin inhibited cytoplasmic streaming in T. fluminensis, organelle movement of peroxi-somesperoxisomes, and the Golgi apparatus in a concentration-dependent manner. It also destroyed the correct root tip distribution of auxin, which probably contributed to the observed inhibition of root growth. These observations of the disruption of cytoskeleton-dependent transport processes in plant cells add a new facet to the mechanism of action of allicin as a redox toxin in cells
On the Perturbation of Synchrotron Motion in the Micro-Bunching Instability
The self-interaction of short electron bunches with their own radiation field
can have a significant impact on the longitudinal beam dynamics in a storage
ring. While higher bunch currents increase the power of the emitted CSR which
can be provided to dedicated experiments, it simultaneously amplifies the
strength of the self-interaction. Eventually, this leads to the formation of
dynamically changing micro-structures within the bunch and thus fluctuating CSR
emission, a phenomenon that is generally known as micro-bunching or micro-wave
instability. The underlying longitudinal dynamics can be simulated by solving
the VFP equation, where the CSR self-interaction can be added as a perturbation
to the Hamiltonian. In this contribution, we focus on the perturbation of the
synchrotron motion that is caused by introducing this additional wake field.
Therefore, we adopt the perspective of a single particle and eventually comment
on its implications for collective motion. We explicitly show how the shape of
the parallel plates CSR wake potential breaks homogeneity in the longitudinal
phase space and propose a quadrupole-like mode as potential seeding mechanism
of the micro-bunching instability. Moreover, we consider synchrotron motion
above the instability threshold and thereby motivate an approach to control of
the occurring micro-bunching dynamics. Using dynamically adjusted RF amplitude
modulations we can directly address the continuous CSR-induced perturbation at
the timescale of its occurrence, which allows for substantial control over the
longitudinal charge distribution. While the approach is not limited to this
particular application, we demonstrate how this can significantly mitigate the
micro-bunching dynamics directly above the instability threshold. The gained
insights are supported and verified using the VFP solver Inovesa and put into
context with measurements at KARA
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