3,297 research outputs found

    A causal multifractal stochastic equation and its statistical properties

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    Multiplicative cascades have been introduced in turbulence to generate random or deterministic fields having intermittent values and long-range power-law correlations. Generally this is done using discrete construction rules leading to discrete cascades. Here a causal log-normal stochastic process is introduced; its multifractal properties are demonstrated together with other properties such as the composition rule for scale dependence and stochastic differential equations for time and scale evolutions. This multifractal stochastic process is continuous in scale ratio and in time. It has a simple generating equation and can be used to generate sequentially time series of any length.Comment: Eur. Phys. J. B (in press

    Lagrangian Cascade in Three-Dimensional Homogeneous and Isotropic Turbulence

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    In this work, the scaling statistics of the dissipation along Lagrangian trajectories are investigated by using fluid tracer particles obtained from a high resolution direct numerical simulation with Reλ=400Re_{\lambda}=400. Both the energy dissipation rate ϵ\epsilon and the local time averaged ϵτ\epsilon_{\tau} agree rather well with the lognormal distribution hypothesis. Several statistics are then examined. It is found that the autocorrelation function ρ(τ)\rho(\tau) of ln(ϵ(t))\ln(\epsilon(t)) and variance σ2(τ)\sigma^2(\tau) of ln(ϵτ(t))\ln(\epsilon_{\tau}(t)) obey a log-law with scaling exponent β=β=0.30\beta'=\beta=0.30 compatible with the intermittency parameter μ=0.30\mu=0.30. The qqth-order moment of ϵτ\epsilon_{\tau} has a clear power-law on the inertial range 10<τ/τη<10010<\tau/\tau_{\eta}<100. The measured scaling exponent KL(q)K_L(q) agrees remarkably with qζL(2q)q-\zeta_L(2q) where ζL(2q)\zeta_L(2q) is the scaling exponent estimated using the Hilbert methodology. All these results suggest that the dissipation along Lagrangian trajectories could be modelled by a multiplicative cascade.Comment: 10 pages with 7 figures accepted for Journal of Fluid Mechanics as Rapid

    Time dependent intrinsic correlation analysis of temperature and dissolved oxygen time series using empirical mode decomposition

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    In the marine environment, many fields have fluctuations over a large range of different spatial and temporal scales. These quantities can be nonlinear \red{and} non-stationary, and often interact with each other. A good method to study the multiple scale dynamics of such time series, and their correlations, is needed. In this paper an application of an empirical mode decomposition based time dependent intrinsic correlation, \red{of} two coastal oceanic time series, temperature and dissolved oxygen (saturation percentage) is presented. The two time series are recorded every 20 minutes \red{for} 7 years, from 2004 to 2011. The application of the Empirical Mode Decomposition on such time series is illustrated, and the power spectra of the time series are estimated using the Hilbert transform (Hilbert spectral analysis). Power-law regimes are found with slopes of 1.33 for dissolved oxygen and 1.68 for temperature at high frequencies (between 1.2 and 12 hours) \red{with} both close to 1.9 for lower frequencies (time scales from 2 to 100 days). Moreover, the time evolution and scale dependence of cross correlations between both series are considered. The trends are perfectly anti-correlated. The modes of mean year 3 and 1 year have also negative correlation, whereas higher frequency modes have a much smaller correlation. The estimation of time-dependent intrinsic correlations helps to show patterns of correlations at different scales, for different modes.Comment: 35 pages with 22 figure

    Tatouage fragile d'objets 3D triangulés

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    Nous proposons une nouvelle méthode de tatouage fragile adaptée au marquage des objets maillés tridimensionnels et triangularisés, basée sur la modification d'invariants géométriques. Nous utilisons une localisation compacte indexée de l'information cachée, et nous vérifions la robustesse du schéma global de tatouage face à l'attaque de coupe

    Impact of age, leukocyte count and day 21-bone marrow response to chemotherapy on the long-term outcome of children with philadelphia chromosome-positive acute lymphoblastic leukemia in the pre-imatinib era: results of the FRALLE 93 study

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    <p>Abstract</p> <p>Background</p> <p>We explored the heterogeneity of philadelphia chromosome-positive acute lymphoblastic leukemia (Ph1-ALL) in a study of the effect of early features on prognosis in children. Here we report the long-term results of the FRALLE 93 study conducted in the era before the use of tyrosine kinase inhibitors.</p> <p>Methods</p> <p>Between 1993 and 1999, 36 children with Ph1-ALL were enrolled into the FRALLE 93 protocol. After conventional four-drug induction, children were stratified by availability of an HLA-matched sibling.</p> <p>Results</p> <p>Complete remission (CR) was observed in 26 children (72%), of which 13 underwent allogeneic bone marrow transplantation (BMT). Thirty-one children were good responders to prednisone, defined on day 8, and 21 were good responders to chemotherapy, defined by day-21 bone marrow (M1). Overall five-year disease-free survival (DFS) was 42 ± 9.7%. Based on multivariate analysis, two groups showed marked differences in five-year outcome: children with age<10, leukocyte count <100,000/mm<sup>3 </sup>and day-21 M1 marrow had a more favorable prognosis (14 pts: 100% CR, event free survival [EFS]: 57%, overall survival [OS]: 79%), than the high-risk group (22 patients: 55% CR, EFS: 18%, OS: 27%) (p < 0.005). We also observed a non statistically significant difference (p = 0.14) in outcome between these groups for transplanted patients (5-year DFS: 83 ± 14% and 33 ± 15%, respectively).</p> <p>Conclusion</p> <p>Age, leukocyte count and early response to treatment defined by the D21 bone marrow response provide an accurate model for outcome prediction. The combination of available tools such as minimal residual disease assessment with determination of these simple factors could be useful for refining indications for BMT in the current era of tyrosine-kinase inhibitor-based therapy.</p
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