11 research outputs found
Creating Social Enterprises in FairShares Labs
In this book, six partner organisations describe FairShares Labs for Social and Blue Innovation. They offer a vision of how to create social enterprise incubators that nurture inclusive multi-stakeholder co-operative enterprises. Building on the theory and practice of Living Labs, Social and Blue Economy and the FairShares Model the text of Creating Social Enterprises in FairShares Labs sets out the concepts, processes and methods for building a FairShares Lab
Methodology for Creating a FairShares Lab (Full Report)
Welcome to the full version of the first intellectual output (IO1) of the Erasmus+ project FairShares Labs for Social and Blue Innovation Project (Project 2016-1-DE02-KA204-003397). IO1 has been prepared by project partners to describe their methodology for creating FairShares Labs. Work started in Erfurt, Germany (7-9 December 2016) and has been discussed in three further transnational meetings in Sheffield (26-28 June 2017), Berlin (27-28 August 2017) and Osijek (20-22 Feb 2018).
In this document, we set out the purpose of IO1.
This document provides any person involved in the creation and development of a FairShares Lab (partners, coordinators, trainers and advisers) with an overview of the methodology for creating their lab. This includes an account of the FairShares Model itself as well as processes for setting up, recruiting people to and marketing a FairShares Lab, and supporting lab participants as they incubate new FairShares enterprises and contribute to building an ecosystem for FairShares.
Section 1 provides background information and an overview of the methodology. Section 2 provides an overview of five elements of a FairShares Lab. Three elements come from the FairShares Model of social enterprise development (created by FairShares Association Ltd) - values and principles; key questions and; legal choices. The other two elements are social and technical support systems selected by the partners for this project. Social support is provided through learning and development methods (elaborated further in Section 3). These generate ideas, improve the effectiveness of team work and enable stakeholders to make decisions together. In Section 4, we examine the process of establishing a lab, inviting people to it, running activities, selecting projects, producing prototypes of goods and services, planning and incorporating (social) enterprises. In Section 5, we consider the marketing of FairShares Labs, who they are for, what needs they serve, what messages should be communicated to target groups (and future lab organisers)
Methodology for Creating a FairShares Lab
Welcome to the first intellectual output (IO1) of the Erasmus+ project FairShares Labs for Social and Blue Innovation Project (Project 2016-1-DE02-KA204-003397). IO1 has been prepared by project partners to describe their methodology for creating FairShares Labs. Work started in Erfurt, Germany (7-9 December 2016) and has been discussed in three further transnational meetings in Sheffield (26-28 June 2017), Berlin (27-28 August 2017) and Osijek (20-22 Feb 2018).
In this document, we set out the purpose of IO1.
This document provides any person involved in the creation and development of a FairShares Lab (partners, coordinators, trainers and advisers) with an overview of the methodology for creating their lab. This includes an account of the FairShares Model itself as well as processes for setting up, recruiting people to and marketing a FairShares Lab, and supporting lab participants as they incubate new FairShares enterprises and contribute to building an ecosystem for FairShares.
Section 1 provides background information and an overview of the methodology. Section 2 provides an overview of five elements of a FairShares Lab. Three elements come from the FairShares Model of social enterprise development (created by FairShares Association Ltd) - values and principles; key questions and; legal choices. The other two elements are social and technical support systems selected by the partners for this project. Social support is provided through learning and development methods (elaborated further in Section 3). These generate ideas, improve the effectiveness of team work and enable stakeholders to make decisions together. In Section 4, we examine the process of establishing a lab, inviting people to it, running activities, selecting projects, producing prototypes of goods and services, planning and incorporating (social) enterprises. In Section 5, we consider the marketing of FairShares Labs, who they are for, what needs they serve, what messages should be communicated to target groups (and future lab organisers)
European Peer Counselor Training in Accessible Tourism – Peer Act" Innovation for Inclusion in Adult Training and Inclusive Tourism
n/
A fibroblast heparan sulphate proteoglycan with a 70 kDa core protein is linked to membrane phosphatidylinositol
Here we present evidence that a fibroblast heparan sulphate proteoglycan of approx. 300 kDa and with a core protein of apparent molecular mass 70 kDa is covalently linked to the plasma membrane via a linkage structure involving phosphatidylinositol. Phosphatidylinositol-specific phospholipase C releases such a heparan sulphate proteoglycan only from cells labelled with [35S]sulphate in the absence of serum. Cell cultures labelled with [3H]myo-inositol in the absence or presence of serum produce a radiolabelled heparan sulphate proteoglycan which was purified by gel-permeation chromatography and ion-exchange chromatography on MonoQ. Digestion with heparan sulphate lyase and analysis by gel-permeation chromatography and sodium dodecylsulphate-polyacrylamide gel-electrophoresis revealed that the 3H-label is associated with a core protein of apparent mass 70 kDa
Nanomechanical Recognition of <i>N</i>-Methylammonium Salts
Turning molecular recognition into an effective mechanical
response
is critical for many applications ranging from molecular motors and
responsive materials to sensors. Herein, we demonstrate how the energy
of the molecular recognition between a supramolecular host and small
alkylammonium salts can be harnessed to perform a nanomechanical task
in a univocal way. Nanomechanical Si microcantilevers (MCs) functionalized
by a film of tetra-phosphonate cavitands were employed to screen as
guests the compounds of the butylammonium chloride series <b>1</b>–<b>4</b>, which comprises a range of low molecular
weight (LMW) molecules (molecular mass < 150 Da) that differ from
each other by one or a few <i>N</i>-methyl groups (molecular
mass 15 Da). The cavitand surface recognition of each individual guest
drove a specific MC bending (from a few to several tens of nanometer),
disclosing a direct, label-free, and real-time mean to sort them.
The complexation preferences of tetraphosphonate cavitands toward
ammonium chloride guests <b>1</b>–<b>4</b> were
independently assessed by isothermal titration calorimetry. Both direct
and displacement binding experiments concurred to define the following
binding order in the alkylammonium series: <b>2</b> > <b>3</b> ≈ <b>1</b> ≫ <b>4</b>. This trend
is consistent with the number of interactions established by each
guest with the host. The complementary ITC experiments showed that
the host–guest complexation affinity in solution is transferred
to the MC bending. These findings were benchmarked by implementing
cavitand-functionalized MCs to discriminate sarcosine from glycine
in water