194 research outputs found
Scientists in the Classroom
Being an educator in the twenty-first century is exciting, stimulating, fun, challenging, and dynamic - with a great emphasis on the challenging and dynamic. The scope and depth of the materials we teach, or can teach, to our students is overwhelming and increasing exponentially every year. The list of challenges for science educators is formidable. We have found that one logical piece of the puzzle to help address these challenges is for educators to invite practicing and real-world researchers, engineers, doctors, business owners, and other STEM (science, technology, engineering, mathematics) professionals into the classroom, or take students on field trips to businesses and industries. These scientists in the classroom do not come as mere guest speakers, as an add-on or afterthought, and are not meant to be an interesting diversion from the normal schedule and curriculum. Quite the opposite, the explicit purpose for their presence is to assist and support the teacher, and to present, teach, and discuss discrete, focused, and curriculum-related lessons and topics
Dominant g(9/2)^2 neutron configuration in the 4+1 state of 68Zn based on new g factor measurements
The factor of the state in Zn has been remeasured with
improved energy resolution of the detectors used. The value obtained is
consistent with the previous result of a negative factor thus confirming
the dominant neutron nature of the state. In addition, the
accuracy of the factors of the , and states has been
improved an d their lifetimes were well reproduced. New large-scale shell model
calculations based on a Ni core and an model space
yield a theoretical value, . Although the calculated value
is small, it cannot fully explain the experimental value, . The magnitude of the deduced B(E2) of the and
transition is, however, rather well described. These results demonstrate again
the importance of factor measurements for nuclear structure determination s
due to their specific sensitivity to detailed proton and neutron components in
the nuclear wave functions.Comment: 7 pages, 3 figs, submitted to PL
Magnetic dipole probes of the sd and pf shell crossing in the A=36,38 argon isotopes
We have calculated the M1 strength distributions in the A=36,38 argon
isotopes within large-scale shell model studies which consider valence nucleons
in the sd and pf shells. While the M1 strength in 36Ar is well reproduced
within the sd shell, the experimentally observed strong fragmentation of the M1
strength in 38Ar requires configuration mixing between the sd and the pf shells
adding to our understanding of correlations across the N=20 shell gap.Comment: 14 pages, 8 figure
Predation efficiency of Anopheles gambiae larvae by aquatic predators in western Kenya highlands
Abstract Background The current status of insecticide resistance in mosquitoes and the effects of insecticides on non-target insect species have raised the need for alternative control methods for malaria vectors. Predation has been suggested as one of the important regulation mechanisms for malaria vectors in long-lasting aquatic habitats, but the predation efficiency of the potential predators is largely unknown in the highlands of western Kenya. In the current study, we examined the predation efficiency of five predators on Anopheles gambiae s.s larvae in 24 hour and semi- field evaluations. Methods Predators were collected from natural habitats and starved for 12 hours prior to starting experiments. Preliminary experiments were conducted to ascertain the larval stage most predated by each predator species. When each larval instar was subjected to predation, third instar larvae were predated at the highest rate. Third instar larvae of An. gambiae were introduced into artificial habitats with and without refugia at various larval densities. The numbers of surviving larvae were counted after 24 hours in 24. In semi-field experiments, the larvae were counted daily until they were all either consumed or had developed to the pupal stage. Polymerase chain reaction was used to confirm the presence of An. gambiae DNA in predator guts. Results Experiments found that habitat type (P < 0.0001) and predator species (P < 0.0001) had a significant impact on the predation rate in the 24 hour evaluations. In semi-field experiments, predator species (P < 0.0001) and habitat type (P < 0.0001) were significant factors in both the daily survival and the overall developmental time of larvae. Pupation rates took significantly longer in habitats with refugia. An. gambiae DNA was found in at least three out of ten midguts for all predator species. Gambusia affins was the most efficient, being three times more efficient than tadpoles. Conclusion These experiments provide insight into the efficiency of specific natural predators against mosquito larvae. These naturally occurring predators may be useful in biocontrol strategies for aquatic stage An. gambiae mosquitoes. Further investigations should be done in complex natural habitats for these predators
A Novel Phase Variation Mechanism in the Meningococcus Driven by a Ligand-Responsive Repressor and Differential Spacing of Distal Promoter Elements
Phase variable expression, mediated by high frequency reversible changes in the length of simple sequence repeats, facilitates adaptation of bacterial populations to changing environments and is frequently important in bacterial virulence. Here we elucidate a novel phase variable mechanism for NadA, an adhesin and invasin of Neisseria meningitidis. The NadR repressor protein binds to operators flanking the phase variable tract and contributes to the differential expression levels of phase variant promoters with different numbers of repeats likely due to different spacing between operators. We show that IHF binds between these operators, and may permit looping of the promoter, allowing interaction of NadR at operators located distally or overlapping the promoter. The 4-hydroxyphenylacetic acid, a metabolite of aromatic amino acid catabolism that is secreted in saliva, induces NadA expression by inhibiting the DNA binding activity of the repressor. When induced, only minor differences are evident between NadR-independent transcription levels of promoter phase variants and are likely due to differential RNA polymerase contacts leading to altered promoter activity. Our results suggest that NadA expression is under both stochastic and tight environmental-sensing regulatory control, both mediated by the NadR repressor, and may be induced during colonization of the oropharynx where it plays a major role in the successful adhesion and invasion of the mucosa. Hence, simple sequence repeats in promoter regions may be a strategy used by host-adapted bacterial pathogens to randomly switch between expression states that may nonetheless still be induced by appropriate niche-specific signals
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