576 research outputs found
High mobility work station restraint support
Chair holds man in semistanding posture enabling astronauts to work comfortably with minimum restriction in weightless environment. Seat, angled at 130 deg to back support, twists and swivels up to 20 deg in all directions but forward. Two flexible thigh clips prevent occupant from slipping off
Management
There’s no question that today’s business environments are rapidly changing. And that’s why John Schermerhorn’s new Seventh Edition of MANAGEMENT gives you the knowledge and skills they need to succed, no matter what the future holds! No other management text makes a stronger connection to today’s dynamic new workplace, offers as many career-enhancing resources, and is more throughly integrated with the webth
As you read the text, you’ll find numerous web links that encourage you to use the internet to explore topics in more depth. In addition,the seventh edition provides a wealth of valuable web-based resources at the E-Resource centre (www.wiley.com/college/schermerhorn).the e-resource center features:
.Study guide – powerpoint chapter outlines and interactive self-testing.
.Interactive cases – online case studies for each chapter in the text.
.Interactive self-assessments-assessments for managerial style and readiness.
.The career advancement portfolio – student career planning and advancement templates,as well as an outcome assessment framework.
.Fast company articles – selected thought–provoking articles from fast company magazine.
. Reality checks – sections that challenge students’ assumptions of what they think they know about the business environment
In vitro increase of mean corpuscular volume difference (dMCV) as a marker for serum hypertonicity in dogs.
Spurious increase in erythrocyte mean corpuscular volume (MCV) on automated cell analyzers is a well-characterized lab error in hypertonic patients. A difference between automated and manual MCV (dMCV) greater than 2 fl has been shown to predict hypertonicity in humans. The purpose of this study was to investigate dMCV as a marker for serum hypertonicity in dogs and to examine the relationship between dMCV and three methods of estimating serum tonicity: measured (OsM_M), calculated (OsM_C), and calculated effective (OsM_CE) osmolalities. OsM_C, OsM_CE, and dMCV were calculated from routine blood values and OsM_M was directly measured in 121 dogs. The dMCV of hypertonic dogs was significantly larger than that of normotonic dogs for all three osmolality methods. dMCV predicted hypertonicity as estimated by OsM_M better than it predicted hypertonicity as estimated by OsM_C and OsM_CE. A cutoff of 2.96 fl yielded the best sensitivity (76%) and specificity (71%) for hypertonicity estimated by OsMM
ATP-sensitive potassium channel (K(ATP )channel) expression in the normal canine pancreas and in canine insulinomas
BACKGROUND: Pancreatic beta cells express ATP-sensitive potassium (K(ATP)) channels that are needed for normal insulin secretion and are targets for drugs that modulate insulin secretion. The K(ATP )channel is composed of two subunits: a sulfonylurea receptor (SUR 1) and an inward rectifying potassium channel (Kir(6.2)). K(ATP )channel activity is influenced by the metabolic state of the cell and initiates the ionic events that precede insulin exocytosis. Although drugs that target the K(ATP )channel have the expected effects on insulin secretion in dogs, little is known about molecular aspects of this potassium channel. To learn more about canine beta cell K(ATP )channels, we studied K(ATP )channel expression by the normal canine pancreas and by insulin-secreting tumors of dogs. RESULTS: Pancreatic tissue from normal dogs and tumor tissue from three dogs with histologically-confirmed insulinomas was examined for expression of K(ATP )channel subunits (SUR1 and Kir(6.2)) using RT-PCR. Normal canine pancreas expressed SUR1 and Kir(6.2 )subunits of the K(ATP )channel. The partial nucleotide sequences for SUR1 and Kir(6.2 )obtained from the normal pancreas showed a high degree of homology to published sequences for other mammalian species. SUR1 and Kir(6.2 )expression was observed in each of the three canine insulinomas examined. Comparison of short sequences from insulinomas with those obtained from normal pancreas did not reveal any mutations in either SUR1 or Kir(6.2 )in any of the insulinomas. CONCLUSION: Canine pancreatic K(ATP )channels have the same subunit composition as those found in the endocrine pancreases of humans, rats, and mice, suggesting that the canine channel is regulated in a similar fashion as in other species. SUR1 and Kir(6.2 )expression was found in the three insulinomas examined indicating that unregulated insulin secretion by these tumors does not result from failure to express one or both K(ATP )channel subunits
Strategy Implementation Styles Of Malaysian, Thai And Hungarian Middle Managers
There is a need for more comparative empirical research that examines middle manager
roles in strategic change. This paper reports a study of middle managers in two dynamic
settings: the Asia/Pacific region – Malaysia and Thailand; and Central/Eastern Europe –
Hungary. Results of 213 respondents across three countries indicate that middle managers
from all three tend toward use of authoritarian management styles even in proactive
strategic change situations. However, Hungarians are less likely to use these styles than Thai
and Malaysian middle managers. For all three countries, managers with less work
experience were found to have lower tendencies to use an authoritarian style of
implementation. When top managers exhibit an aggressive strategic posture, middlemanagers from all three countries are also less likely to use an authoritarian style
‘Ethnic group’, the state and the politics of representation
The assertion, even if only by implication, that ‘ethnic group’ categories represent ‘real’ tangible entities, indeed identities, is commonplace not only in the realms of political and policy discourse but also amongst contemporary social scientists. This paper, following Brubaker (2002), questions this position in a number of key respects: of these three issues will dominate the discussion that follows.
First, there is an interrogation of the proposition that those to whom the categories/labels refer constitute sociologically meaningful ‘groups’ as distinct from (mere) human collectivities. Secondly, there is the question of how these categories emerge, i.e. exactly what series of events, negotiations and contestations lie behind their construction and social acceptance. Thirdly, and as a corollary to the latter point, we explore the process of reification that leads to these categories being seen to represent ‘real things in the world’ (ibid.)
Editor's Choice - Optimal Threshold for the Volume-Outcome Relationship After Open AAA Repair in the Endovascular Era : Analysis of the International Consortium of Vascular Registries
Objective: As open abdominal aortic aneurysm (AAA) repair (OAR) rates decline in the endovascular era, the endorsement of minimum volume thresholds for OAR is increasingly controversial, as this may affect credentialing and training. The purpose of this analysis was to identify an optimal centre volume threshold that is associated with the most significant mortality reduction after OAR, and to determine how this reflects contemporary practice. Methods: This was an observational study of OARs performed in 11 countries (2010 - 2016) within the International Consortium of Vascular Registry database (n = 178 302). The primary endpoint was post-operative in hospital mortality. Two different methodologies (area under the receiving operating curve optimisation and Markov chain Monte Carlo procedure) were used to determine the optimal centre volume threshold associated with the most significant mortality improvement. Results: In total, 154 912 (86.9%) intact and 23 390 (13.1%) ruptured AAAs were analysed. The majority (63.1%; n = 112 557) underwent endovascular repair (EVAR) (OAR 36.9%; n = 65 745). A significant inverse relationship between increasing centre volume and lower peri-operative mortality after intact and ruptured OAR was evident (p = 13 procedures/year volume threshold, with significant variation between nations (Germany 11%; Denmark 100%). Conclusion: An annual centre volume of 13 - 16 OARs per year is the optimal threshold associated with the greatest mortality risk reduction after treatment of intact AAA. However, in the current endovascular era, achieving this threshold requires significant re-organisation of OAR practice delivery in many countries, and would affect provision of non-elective aortic services. Low volume centres continuing to offer OAR should aim to achieve mortality results equivalent to the high volume institution benchmark, using validated data from quality registries to track outcomes.Peer reviewe
Editor's Choice – European Society for Vascular Surgery (ESVS) 2023 Clinical Practice Guidelines on the Management of Atherosclerotic Carotid and Vertebral Artery Disease
info:eu-repo/semantics/publishedVersio
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