Knocking on the door : police decision points in executing search warrants.

Research indicates that search warrants raids increased during the 1990s and continue to be a common enforcement tool for law enforcement. The extant literature does not provide a detailed understanding of why police departments are increasingly using search warrants and in particular why plainclothes detectives are conducting these raids at a higher rate. Furthermore, the research does not provide an understanding for how search warrants are secured and executed by police departments. This research examines the social constructions detectives use to justify and carry out the various stages of the search warrant process. Ethnographic research was used to observe 73 search warrants over a 21 month period. The findings indicate there are five stages to the search warrant process: (1) when detectives seek warrants; (2) obtaining the warrant; (3) preparing for the warrant; (4) executing the warrant; and (5) measuring the warrant’s success. When examining the search warrant process as a whole, the research finds those detectives’ typifications of the need for search warrants rests on the officer safety and the need to secure evidence of criminal activity before it is destroyed. The research also shows the detectives’ emphasis on safety is contradictory as the process detectives use to execute search warrant exposes the detectives to increased and often unnecessary risks

Melting and freezing of argon in a granular packing of linear mesopore arrays

Freezing and melting of Ar condensed in a granular packing of template-grown arrays of linear mesopores (SBA-15, mean pore diameter 8 nanometer) has been studied by specific heat measurements C as a function of fractional filling of the pores. While interfacial melting leads to a single melting peak in C, homogeneous and heterogeneous freezing along with a delayering transition for partial fillings of the pores result in a complex freezing mechanism explainable only by a consideration of regular adsorption sites (in the cylindrical mesopores) and irregular adsorption sites (in niches of the rough external surfaces of the grains, and at points of mutual contact of the powder grains). The tensile pressure release upon reaching bulk liquid/vapor coexistence quantitatively accounts for an upward shift of the melting/freeezing temperature observed while overfilling the mesopores.Comment: 4 pages, 4 figures, to appear as a Letter in Physical Review Letter

Combination of common mtDNA variants results in mitochondrial dysfunction and a connective tissue dysregulation

Mitochondrial dysfunction can be associated with a range of clinical manifestations. Here, we report a family with a complex phenotype including combinations of connective tissue, neurological, and metabolic symptoms that were passed on to all surviving children. Analysis of the maternally inherited mtDNA revealed a novel genotype encompassing the haplogroup J - defining mitochondrial DNA (mtDNA

The determination of αs\alpha_s by the ALPHA collaboration

We review the ALPHA collaboration strategy for obtaining the QCD coupling at high scale. In the three-flavor effective theory it avoids the use of perturbation theory at $\alpha > 0.2$ and at the same time has the physical scales small compared to the cutoff $1/a$ in all stages of the computation. The result \Lambda_\overline{MS}^{(3)}=332(14)~MeV is translated to \alpha_\overline{MS}(m_Z)=0.1179(10)(2) by use of (high order) perturbative relations between the effective theory couplings at the charm and beauty quark "thresholds". The error of this perturbative step is discussed and estimated as $0.0002$.Comment: 7 pages, proceedings of FPCapri2016 conferenc

The strong coupling from a nonperturbative determination of the Λ\Lambda parameter in three-flavor QCD

We present a lattice determination of the $\Lambda$ parameter in three-flavor QCD and the strong coupling at the Z pole mass. Computing the nonperturbative running of the coupling in the range from $0.2\,$GeV to $70\,$GeV, and using experimental input values for the masses and decay constants of the pion and the kaon, we obtain $\Lambda_{\overline{\rm MS}}^{(3)}=341(12)\,$MeV. The nonperturbative running up to very high energies guarantees that systematic effects associated with perturbation theory are well under control. Using the four-loop prediction for $\Lambda_{\overline{\rm MS}}^{(5)}/\Lambda_{\overline{\rm MS}}^{(3)}$ yields $\alpha^{(5)}_{\overline{\rm MS}}(m_{\rm Z}) = 0.11852(84)$.Comment: Correction in the comparison to the LHC value for alpha(1.5TeV) which was given by CMS in the 5-flavor theory. The agreement is improved. Also 1 Reference added and a few typos correcte

Memory Organization for Energy-Efficient Learning and Inference in Digital Neuromorphic Accelerators

The energy efficiency of neuromorphic hardware is greatly affected by the energy of storing, accessing, and updating synaptic parameters. Various methods of memory organisation targeting energy-efficient digital accelerators have been investigated in the past, however, they do not completely encapsulate the energy costs at a system level. To address this shortcoming and to account for various overheads, we synthesize the controller and memory for different encoding schemes and extract the energy costs from these synthesized blocks. Additionally, we introduce functional encoding for structured connectivity such as the connectivity in convolutional layers. Functional encoding offers a 58% reduction in the energy to implement a backward pass and weight update in such layers compared to existing index-based solutions. We show that for a 2 layer spiking neural network trained to retain a spatio-temporal pattern, bitmap (PB-BMP) based organization can encode the sparser networks more efficiently. This form of encoding delivers a 1.37x improvement in energy efficiency coming at the cost of a 4% degradation in network retention accuracy as measured by the van Rossum distance.Comment: submitted to ISCAS202

Monitoring of lung edema by microwave reflectometry during lung ischemia-reperfusion injury in vivo

It is still unclear whether lung edema can be monitored by microwave reflectometry and whether the measured changes in lung dry matter content (DMC) are accompanied by changes in PaO(2) and in pro-to anti-inflammatory cytokine expression (IFN-gamma and IL-10). Right rat lung hili were cross-clamped at 37 degrees C for 0, 60, 90 or 120 min ischemia followed by 120 min reperfusion. After 90 min (DMC: 15.9 +/- 1.4%; PaO(2): 76.7 +/- 18 mm Hg) and 120 min ischemia (DMC: 12.8 +/- 0.6%; PaO(2): 43 +/- 7 mm Hg), a significant decrease in DMC and PaO(2) throughout reperfusion compared to 0 min ischemia (DMC: 19.5 +/- 1.11%; PaO(2): 247 +/- 33 mm Hg; p < 0.05) was observed. DMC and PaO(2) decreased after 60 min ischemia but recovered during reperfusion (DMC: 18.5 +/- 2.4%; PaO(2) : 173 +/- 30 mm Hg). DMC values reflected changes on the physiological and molecular level. In conclusion, lung edema monitoring by microwave reflectometry might become a tool for the thoracic surgeon. Copyright (c) 2006 S. Karger AG, Basel

Community-Derived Core Concepts for Neuroscience Higher Education

Core concepts provide a framework for organizing facts and understanding in neuroscience higher education curricula. Core concepts are overarching principles that identify patterns in neuroscience processes and phenomena and can be used as a foundational scaffold for neuroscience knowledge. The need for community-derived core concepts is pressing, because both the pace of research and number of neuroscience programs are rapidly expanding. While general biology and many subdisciplines within biology have identified core concepts, neuroscience has yet to establish a community-derived set of core concepts for neuroscience higher education. We used an empirical approach involving more than 100 neuroscience educators to identify a list of core concepts. The process of identifying neuroscience core concepts was modeled after the process used to develop physiology core concepts and involved a nationwide survey and a working session of 103 neuroscience educators. The iterative process identified eight core concepts and accompanying explanatory paragraphs. The eight core concepts are abbreviated as communication modalities, emergence, evolution, gene–environment interactions, information processing, nervous system functions, plasticity, and structure–function. Here, we describe the pedagogical research process used to establish core concepts for the neuroscience field and provide examples on how the core concepts can be embedded in neuroscience education

Constraints on the Progenitor System of the Type Ia Supernova 2014J from Pre-Explosion Hubble Space Telescope Imaging

We constrain the properties of the progenitor system of the highly reddened Type Ia supernova (SN) 2014J in Messier 82 (M82; d ~ 3.5 Mpc). We determine the SN location using Keck-II K-band adaptive optics images, and we find no evidence for flux from a progenitor system in pre-explosion near-ultraviolet through near-infrared Hubble Space Telescope (HST) images. Our upper limits exclude systems having a bright red giant companion, including symbiotic novae with luminosities comparable to that of RS Ophiuchi. While the flux constraints are also inconsistent with predictions for comparatively cool He-donor systems (T < ~35,000 K), we cannot preclude a system similar to V445 Puppis. The progenitor constraints are robust across a wide range of R_V and A_V values, but significantly greater values than those inferred from the SN light curve and spectrum would yield proportionally brighter luminosity limits. The comparatively faint flux expected from a binary progenitor system consisting of white dwarf stars would not have been detected in the pre-explosion HST imaging. Infrared HST exposures yield more stringent constraints on the luminosities of very cool (T < 3000 K) companion stars than was possible in the case of SN Ia 2011fe.Comment: Accepted by ApJ 14 May 2014 with only minor revision