421 research outputs found

    Albrecht Durer and the Lutheran Reformation

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    This dissertation is a study of Albrecht Dürer\u27s life and work with a theologioa1 interest. This is in no way a complete discussion of the artist\u27s life and works. The selection of works treated in chapter four is not a good cross section of his drawings, woodcuts. copper engravings, etchings, and paintings. They are a careful selection of his works of art showing how he gradually employed true Christian or Biblical teaching in his religious subjects. The author endeavors to show in this paper that Albrecht Dürer made a contribution to the work of Martin Luther and his associates as a preparatory figure to the reform movement and how later the work of Martin Luther influenced the great German artist

    The Connection Principle and the Classificatory Scheme of Reality

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    Searle's Connection Principle says that "the ascription of an unconscious intentional phenomenon to a system implies that the phenomenon is in principle accessible to consciousness". In this paper I want to defend the thesis that Searle's theory of mind, and especially the Connection Principle, does not offer a coherent picture of unconscious mental states and, a fortiori, of the intentional life generally

    Seguran?a do trabalho como uma dimens?o do projeto de andaimes em obras civis.

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    Programa de P?s-Gradua??o em Constru??o Met?lica. Departamento de Engenharia Civil, Escola de Minas, Universidade Federal de Ouro Preto.Este estudo teve como objetivo geral identificar estrat?gias a serem aplicadas nos projetos de constru??o de andaimes utilizados em constru??o civil, de modo a assegurar a efic?cia dessas estruturas met?licas considerando a seguran?a do trabalhador como uma das dimens?es deste projeto inter-relacionando e contribuindo no planejamento de todo o empreendimento. Optou-se por um estudo de caso complexo, com cronograma restrito, grande intera??o entre equipes e muitas atividades simult?neas, para se produzir um completo levantamento das falhas mais comuns nesse tipo de projeto e, pela mesma raz?o, um equacionamento do fluxo de informa??es seguras proposto por diversos autores de forma a qualificar como bem sucedido os aspectos projetuais adotados e seus impactos em todo o empreendimento. Confrontando a documenta??o da obra, os relatos dos envolvidos e os dados apresentados na literatura sobre o uso de andaimes, foi poss?vel verificar estrat?gias de seguran?a que devem compor os projetos de montagem, utiliza??o e desmontagem de andaimes; analisar os riscos e as barreiras importantes a serem inseridas nos projetos para minimizar e/ou prevenir os acidentes; mapear as poss?veis falhas no processo de elabora??o de projeto; e elaborar um fluxograma de informa??es seguras para serem seguidas nos projetos e utiliza??o de andaimes. Considerar a seguran?a do trabalho como aspecto fundamental em todo o projeto do andaime, seguir adequadamente e cuidadosamente as a??es projetadas e corrigir poss?veis falhas rapidamente, foi de extrema relev?ncia para o sucesso da obra sem acidentes. Contudo a cultura de seguran?a j? estabelecida nas empresas e equipes envolvidas na obra tamb?m foi importante para o sucesso desta. Sendo assim considerou-se que boas pr?ticas de an?lise de riscos contempladas nos projetos apresentam processos para melhoria cont?nua na seguran?a dos trabalhadores e antecipa??o de incertezas.The objective of this study was to identify strategies to be applied in scaffold construction projects used in civil construction, in order to ensure the effectiveness of these metallic structures, considering worker safety as one of the dimensions of this project, interrelating and contributing to the planning of whole enterprise. We chose a complex case study, with a restricted schedule, great interaction between teams and many simultaneous activities to produce a complete survey of the most common failures in this type of project and, for the same reason, a safe information flow equation proposed by several authors in order to qualify as successful the design aspects adopted and their impacts throughout the enterprise. Confronting the documentation of the work, the reports of the workers involved and the data presented in the literature on the use of scaffolding, it was possible to verify security strategies that should compose the projects of assembly, use and disassembly of scaffolding; analyze the risks and important barriers to be included in the projects to minimize and / or prevent accidents; mapping possible failures in the project design process; and develop a flow chart of safe information to be followed in the design and use of scaffolding. Considering work safety as a fundamental aspect of the entire scaffolding project, following carefully and carefully the actions designed and correcting possible faults quickly, Is extremely relevant to the success of the work without accidents. However, the safety culture already established in the companies and teams involved in the work was also important for its success. Thus, it was considered that good practices of risk analysis contemplated in the projects present processes for continuous improvement in the safety of workers and anticipation of uncertainties

    SCAR Report on Antarctic Climate Change and the Environment

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    The first comprehensive review of the state of Antarctica’s climate and its relationship to the global climate by the Scientific Committee on Antarctic Research (SCAR). The review - Antarctic Climate Change and the Environment – presents the latest research from the icy continent, identifies areas for future scientific research, and addresses the urgent questions that policy makers have about Antarctic melting, sea-level rise and biodiversity

    Teratogenic potential of nanoencapsulated vitamin A evaluated on an alternative model organism, the tunicate Ciona intestinalis

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    Nano-encapsulation is a technology used to pack substances in order to enhance their stability and bioavailability, but this packing may interact with living systems, causing unexpected toxicity. Vitamin A (vit A) is a substance that has received attention, because in developed countries, the increasing availability of supplements is leading to its excessive intake. This study aims to compare teratogenic effects caused by exposure to the traditional formulation of vit A versus nano-encapsulated vit A. We used ascidian embryos as an alternative model. Ascidians are marine organisms closely related to vertebrates that share with them a body plan and developmental programme, including the morphogenetic role of retinoic acid (RA). Our data showed that the adverse effects of exposure to the same concentration of the two formulations were different, suggesting that the nano-encapsulation increased the bioavailability of the molecule, which could be better absorbed and metabolised to RA, the effective teratogenic substance

    miR-7 Knockdown by Peptide Nucleic Acids in the Ascidian Ciona intestinalis

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    Peptide Nucleic Acids (PNAs) are synthetic mimics of natural oligonucleotides, which bind complementary DNA/RNA strands with high sequence specificity. They display numerous advantages, but in vivo applications are still rare. One of the main drawbacks of PNAs application is the poor cellular uptake that could be overcome by using experimental models, in which microinjection techniques allow direct delivery of molecules into eggs. Thus, in this communication, we investigated PNAs efficiency in miR-7 downregulation and compared its effects with those obtained with the commercially available antisense molecule, Antagomir (Dharmacon) in the ascidian Ciona intestinalis. Ascidians are marine invertebrates closely related to vertebrates, in which PNA techniques have not been applied yet. Our results suggested that anti-miR-7 PNAs were able to reach their specific targets in the developing ascidian embryos with high efficiency, as the same effects were obtained with both PNA and Antagomir. To the best of our knowledge, this is the first evidence that unmodified PNAs can be applied in in vivo knockdown strategies when directly injected into eggs

    When Credit Bites Back

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    When Credit Bites Back

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    Factors driving semi-aquatic predator occurrence in traditional cattle drinking pools : conservation issues

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    In several cases, human impact on water bodies and on their freshwater communities is detrimental, but in some cases the human activity may favour and enhance the biodiversity of small water bodies, as traditional cattle drinking pools. Despite their small size, small water bodies may constitute hot spot of biodiversity often representing the only lentic aquatic biotope in landscapes where superficial water lacks or flows in lotic environments like creeks and streams. Predators are good indicators of biodiversity in ponds and give information of food chain web complexity. In particular, semi-aquatic predators like amphibians and dragonflies may account for a substantial percentage of energy flow between aquatic and terrestrial ecosystems. In this study, we evaluated the conservation value of traditional cattle drinking pools building by assessing the factors determining the occurrence and distribution of the semiaquatic predators. From April to August 2015, we investigated 30 distinct pools recording several abiotic and biotic environmental variables. We detected 4 semi-aquatic predators: Salamandra salamandra larvae, Triturus carnifex, Aeshna sp. larvae and Libellula sp. larvae. Abiotic features played a major role in shaping the predator community that resulted linked to stable, with no dryness period, and large drinking pools. Invertebrate prey biomass was not particularly important, while vegetation cover and occurrence of unpalatable tadpoles were the most important biotic features of the pools. Our study provides novel evidence on the importance of cattle drinking pools management to preserve biodiversity especially in areas where traditional pastoral activity is disappearing
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