351 research outputs found
Feasibility of a Readiness Exam for Predicting Radiography Program Success: A Pilot Study
ABSTRACT
Background: Research investigating predictors of academic success in rigorous health science education is valuable for curricular intervention for identified at-risk students. Various predictors of success have been investigated, but the literature is insufficient when examining anatomy and physiology readiness scores as they correlate to radiography curricular success. This pilot study assessed the correlation between readiness exam scores and programmatic course GPA to determine if the scores could be used as a metric for identifying academic success resources for incoming students. Cohorts of the radiography program at a midwestern health sciences center demonstrated a longitudinal trend of difficulty with anatomy and physiology programmatic coursework. Therefore, researchers set out to investigate whether or not readiness exam scores, in addition to the metrics they were already utilizing, could be used as a tool for early academic remediation. Objective: The objective of this study was to determine if the anatomy and physiology readiness exam scores would be reliable indicators of programmatic success in anatomy and physiology program coursework. Design: This investigation occurred in two phases: a retrospective correlational phase and a quasi-experimental phase. Methods: Retrospective data from cohorts that matriculated between 2013 and 2017 (n=91) was collected and de-identified. Data included prerequisite grade point average (GPA) and grades from anatomy and physiology course taken during the program. During the quasi-experimental phase, a sample of students (n=18) completed a readiness examination. The scores from this examination were correlated with prerequisite GPA and program anatomy and physiology GPA. Results: Data analysis revealed prerequisite GPA and the anatomy and physiology section of the readiness examination to be strong and moderate predictors of programmatic anatomy and physiology course grades, respectively. Conclusion: Predictors of curricular success in a radiography program’s anatomy and physiology coursework are essential factors to consider in relation to admissions practices, curricular prerequisite standards, and on-boarding of new students, especially those identified as at-risk
Following the Growth of Sarah\u27s baby: An IPE Activity for Medical Nutrition & Diagnostic Sonography Students
Objectives: Interprofessional education (IPE) involves collaborative learning among students from different professions. While acceptance of these types of activities is increasing, there are opportunities to expand the number of health care professions involved in IPE. The purpose of this study was to explore student perceptions and outcomes after participation in a Diagnostic Medical Sonography (DMS) and Medical Nutrition Education (MNE) interprofessional education activity centered around a clinical case study on fetal growth. Subjects & Methods: The IPE activity was administered to four student cohorts from academic years to 2015-2016 to 2018-2019. Participants included 66 students (n=39 DMS and n=27 MNE). Data was gathered through pre- & post-tests based on a patient case-study and evidence-based search skills knowledge and a post-activity survey. Assessment sessions were held on the first day and on the last day of the activity. Results: There was a statistically significant difference in the mean pre-and post-test scores for the group overall, (p=https://digitalcommons.unmc.edu/cahp_mits_pres/1004/thumbnail.jp
Pressure induced superconductivity in the charge density wave compound TbTe3
A series of high-pressure resistivity measurements on single crystals of
TbTe3 reveal a complex phase diagram involving the interplay of
superconducting, antiferromagnetic and charge density wave orders. The onset of
superconductivity reaches a maximum of ~ 3.5 K (onset) near 75 kbar.Comment: 4 pages, 4 figures; magnetization figure removed due to space
constraints; accepted for publication in Physical Review Letter
A model for uranium, rhenium, and molybdenum diagenesis in marine sediments based on results from coastal locations
Author Posting. © The Author(s), 2009. This is the author's version of the work. It is posted here by permission of Elsevier B.V. for personal use, not for redistribution. The definitive version was published in Geochimica et Cosmochimica Acta 73 (2009): 2938-2960, doi:10.1016/j.gca.2009.02.029.The purpose of this research is to characterize the mobilization and
immobilization processes that control the authigenic accumulation of uranium (U),
rhenium (Re) and molybdenum (Mo) in marine sediments. We analyzed these redox–
sensitive metals (RSM) in benthic chamber, pore water and solid phase samples at a site
in Buzzards Bay, Massachusetts, U.S.A., which has high bottom water oxygen
concentrations (230–300 mol/L) and high organic matter oxidation rates (390 mol
C/cm2/y). The oxygen penetration depth varies from 2–9 mm below the sediment–water
interface, but pore water sulfide is below detection (< 2M). The RSM pore water
profiles are modeled with a steady–state diagenetic model that includes irrigation, which
extends 10–20 cm below the sediment–water interface. To present a consistent
description of trace metal diagenesis in marine sediments, RSM results from sediments in
Buzzards Bay are compared with previous research from sulfidic sediments (Morford et
al., GCA 71).
Release of RSM to pore waters during the remineralization of solid phases occurs
near the sediment–water interface at depths above the zone of authigenic RSM formation.
This release occurs consistently for Mo at both sites, but only in the winter for Re in
Buzzards Bay and intermittently for U. At the Buzzards Bay site, Re removal to the solid
phase extends to the bottom of the profile, while the zone of removal is restricted to ~2–9
cm for U and Mo. Authigenic Re formation is independent of the anoxic
remineralization rate, which is consistent with an abiotic removal mechanism. The rate
of authigenic U formation and its modeled removal rate constant increase with increasing
anoxic remineralization rates, and is consistent with U reduction being microbially
mediated. Authigenic Mo formation is related to the formation of sulfidic
microenvironments. The depth and extent of Mo removal from pore water is closely
associated with the balance between iron and sulfate reduction and the consumption of
pore water sulfide via iron sulfide formation. Pore water RSM reach constant asymptotic
concentrations in sulfidic sediments, but only pore water Re is constant at depth in
Buzzards Bay. The increases in pore water U at the Buzzards Bay site are consistent with
addition via irrigation and subsequent upward diffusion to the removal zone. Deep pore
water Mo concentrations exceed its bottom water concentration due to irrigation–induced
oxidation and remobilization from the solid phase. In sulfidic sediments, there is no
evidence for higher pore water U or Mo concentrations at depth due to the absence of
irrigation and/or the presence of more stable authigenic RSM phases.
There are good correlations between benthic fluxes and authigenic accumulation
rates for U and Mo in sulfidic sediments. However, results from Buzzards Bay suggest
irrigation ultimately results in the partial loss of U and Mo from the solid phase, with
accumulation rates that are 20–30% of the modeled flux. Irrigation can augment (Re,
possibly U) or compromise (U, Mo) authigenic accumulation in sediments, and is
important when determining burial rates in continental margin sediments.The authors also acknowledge financial support from the National Science Foundation
(JLM, WRM: OCE–0220892), Research Corporation (JLM, CMC), Franklin & Marshall
College, and the Hackman Summer Research Program at F&M
Vaccines against toxoplasma gondii : challenges and opportunities
Development of vaccines against Toxoplasma gondii infection in humans is of high priority, given the high burden of disease in some areas of the world like South America, and the lack of effective drugs with few adverse effects. Rodent models have been used in research on vaccines against T. gondii over the past decades. However, regardless of the vaccine construct, the vaccines have not been able to induce protective immunity when the organism is challenged with T. gondii, either directly or via a vector. Only a few live, attenuated T. gondii strains used for immunization have been able to confer protective immunity, which is measured by a lack of tissue cysts after challenge. Furthermore, challenge with low virulence strains, especially strains with genotype II, will probably be insufficient to provide protection against the more virulent T. gondii strains, such as those with genotypes I or II, or those genotypes from South America not belonging to genotype I, II or III. Future studies should use animal models besides rodents, and challenges should be performed with at least one genotype II T. gondii and one of the more virulent genotypes. Endpoints like maternal-foetal transmission and prevention of eye disease are important in addition to the traditional endpoint of survival or reduction in numbers of brain cysts after challenge
Role of Condom Negotiation on Condom use among Women of Reproductive Age in three Districts in Tanzania.
ABSTRACT: BACKGROUND: HIV/AIDS remains being a disease of great public health concern worldwide. In regions such as sub-Saharan Africa (SSA) where women are disproportionately infected with HIV, women are reportedly less likely capable of negotiating condom use. However, while knowledge of condom use for HIV prevention is extensive among men and women in many countries including Tanzania, evidence is limited about the role of condom negotiation on condom use among women in rural Tanzania. METHODS: Data originate from a cross-sectional survey of random households conducted in 2011 in Rufiji, Kilombero and Ulanga districts in Tanzania. The survey assessed health-seeking behaviour among women and children using a structured interviewer-administered questionnaire. A total of 2,614 women who were sexually experienced and aged 15--49 years were extracted from the main database for the current analysis. Linkage between condom negotiation and condom use at the last sexual intercourse was assessed using multivariate logistic regression. RESULTS: Prevalence of condom use at the last sexual intercourse was 22.2% overall, ranging from12.2% among married women to 54.9% among unmarried (single) women. Majority of the women (73.4%) reported being confident to negotiate condom use, and these women were significantly more likely than those who were not confident to have used a condom at the last sexual intercourse (OR = 3.13, 95% CI 2.22-4.41). This effect was controlled for marital status, age, education, religion, number of sexual partners, household wealth and knowledge of HIV prevention by condom use. CONCLUSION: Confidence to negotiate condom use is a significant predictor of actual condom use among women in rural Tanzania. Women especially unmarried ones or those in multiple partnerships should be empowered with condom negotiation skills to enhance their sexual and reproductive health outcomes
Associations of cigarette smoking with rheumatoid arthritis in African Americans
To examine the associations of cigarette smoking with rheumatoid arthritis (RA) in African Americans and to determine to whether this association is impacted by HLA-DRB1 shared epitope (SE)
Factors associated with pre-ART loss-to-follow up in adults in rural KwaZulu-Natal, South Africa:a prospective cohort study
Background: Timely initiation of antiretroviral treatment (ART) requires sustained engagement in HIV care before treatment eligibility. We assessed loss to follow-up (LTFU) correlates in HIV-positive adults accessing HIV treatment and care, not yet ART-eligible (CD4 >500 cells/mm3).Methods: This was a sub-study of a prospective cohort study (focusing on sexual behaviour) in an area of high HIV prevalence and widespread ART availability in rural KwaZulu-Natal, South Africa. Psychosocial, clinical and demographic data were collected at recruitment from individuals with CD4 >500 cells/mm3. LTFU was defined as not attending clinic within 13 months of last visit or before death. Individuals starting ART were censored at ART initiation. Data were collected between January 2009 and January 2013. Analysis used Competing Risks regression.Results: Two hundred forty-seven individuals (212 females) were recruited (median follow-up 2.13 years, total follow-up 520.15 person-years). 86 remained in pre-ART care (34.8 %), 94 were LTFU (38.1 %), 58 initiated ART (23.5 %), 7 died (2.8 %), 2 transferred out (0.8 %). The LTFU rate was 18.07 per 100 person-years (95 % CI 14.76–21.12). LTFU before a competing event was 13.5 % at one and 34.4 % at three years. Lower LTFU rates were significantly associated with age (>37 versus ?37 years: adjusted sub-Hazard ratio (aSHR) 0.51, 95 % CI 0.30–0.87), openness with family/friends (a little versus not at all, aSHR 0.81, 95 % CI 0.45–1.43; a lot versus not at all, aSHR 1.57, 95 % CI 0.94–2.62), children (0 versus 4+, aSHR 0.68, 95 % CI 0.24–1.87; 1 versus 4+, aSHR 2.05 95 % CI 1.14–3.69, 2 versus 4+; aSHR 1.71, 95 % CI 0.94–3.09; 3 versus 4a, aSHR 1.14, 95 % CI 0.57–2.30), previous CD4 counts (1 versus 0, aSHR 0.81, 95 % CI 0.45–1.43; 2+ versus 0, aSHR 0.43, 95 % CI 0.25–0.73), and most recent partner HIV status (not known versus HIV-positive, aSHR 0.77, 95 % CI 0.50–1.19; HIV-negative versus HIV-positive, aSHR 2.40, 95 % CI 1.18–4.88). The interaction between openness with family/friends and HIV partner disclosure was close to significance (p?=?0.06). Those who had neither disclosed to partners nor were open with family/friends had lowest LTFU rates.Conclusions: Strategies to retain younger people in pre-ART care are required. How openness with others, partner HIV status and disclosure, and children relate to LTFU needs further exploration.<br/
HIV Prevention in High-Risk Women in South Africa: Condom Use and the Need for Change
INTRODUCTION: Young women are at disproportionate risk of HIV infection in South Africa. Understanding risk behaviors and factors associated with ability to negotiate safe sex and condom use is likely to be key in curbing the spread of HIV. Traditionally prevention efforts have focused on creating behavioral changes by increasing knowledge about HIV/AIDS. METHODS: This was a cross-sectional analysis from a prospective observational cohort study of 245 women at a high-risk of HIV infection in KwaZulu-Natal, South Africa. RESULTS: Participants demonstrated a high level of HIV/AIDS knowledge. Overall, 60.3% of participants reported condom use. Reported condom use at last sexual encounter varied slightly by partner type (57.0% with steady versus 64.4% with casual partners), and self-perceived ability to choose to use a condom was significantly lower with steady partners compared to casual partners (p<0.01). In multivariate analysis, women who had high school education were more likely to use condoms at their last sex encounter compared to those with only primary school education (RR of 1.36 (95% Confidence Interval (CI) 1.06-1.75) and 1.46 (95% CI 1.13-1.88) for grades 8-10 and 11-12, respectively). Those who used condoms as a contraceptive method were twice as likely to use condoms compared to women who did not report using them as a contraceptive method. Greater perceived ability to choose to use condoms was associated with higher self-reported condom use at last encounter, irrespective of partner type (RR = 2.65 (95% CI 2.15-32.5). DISCUSSION: Self-perceived ability to use condoms, level of formal education and condom use as a contraceptive were all significantly associated with self-reported condom use at last sexual encounter. These findings suggest that that gender inequality and access to formal education, as opposed to lack of HIV/AIDS knowledge, prevent safer sexual practices in South Africa
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