Integrating Morita Therapy and Art Therapy: An Analysis

This study presents therapeutic interventions combining Morita Therapy with art therapy techniques. The author presents literature reviews of art therapy as well as the original Morita Therapy formulated by Shoma Morita, M.D. A new art therapy technique based on the work of Kenji Kitanishi, M.D. (2008) for outpatient treatment is also presented. A case illustration of an eleven‐year‐old Vietnamese‐American boy who presented with high anxiety and school refusal is used as an example of the effective integration of Morita Therapy with art therapy techniques formulated by the author. Even though the boy was not familiar with Morita Therapy principles, the creative process helped the client make therapeutic progress. The combined treatment of Morita Therapy principles and art therapy techniques resulted in an effective outcome for the client. As a central concept, Morita Therapy focuses on learning to accept one’s emotions and the reality of one’s life. This analysis concludes that art therapy techniques can be effectively integrated with Morita Therapy as a treatment method aimed at improvement in functioning. The number of clients that can potentially benefit from Morita Therapy increases with the use of art therapy. Given that Morita Therapy is based on Buddhist philosophy, it may be particularly useful Buddhist based cultures

Impact of Integration of Manufacturaing Planning and Control Systems on Supply Chain Management

Manufacturing planning and control systems (MPCSs, for short) are an essentialelement for supply chain processes today. However, there are few researches whichinclude planning information systems in supply chain models and optimize the wholestructure holistically in spite of the social importance of MPCSs for supply chainmanagement. At present, we do not have any ideas even about process behaviorwhen organizations which have MPCSs are linked in a supply chain. To clarifyfundamental properties of supply chain structures including planning informationsystems are tasks of big challenges as well as pressing urgencies. While planninginformation systems and practical activities have been told individually in manyresearches, they should be dealt holistically as a system. This research aims at theingegration of planning systems and practical activities to optimize whole supplychain structures. Actual supply chain processes have million considerable parameters,and they interact each other. It is too complex to deal, so we simplified supplychain processes focusing on interaction between material flow and information flow inthis paper. Firstly we suggested the supply chain process model, and then dynamicproperties of the process are shown. Analyses of the behavior implies managementcapability and limits of the MPCSs. Furthermore, a way of optimization for thesupply chain structure and the effects are shown

Toward a Unified Account of Metonymy

From the perspective of cognitive linguistics, metonymy is a conceptual operation in which one entity maps onto the other entity within a single domain at the conceptual level. There are two related perspectives as to what motivates metonymy: metonymy as having a referential function and metonymy as being motivated by conceptual contiguity. However, there are some linguistic expressions that are less readily identifiable as being motivated in one of these ways. For example, many scholars (e.g., Gibbs 1990, Barnden 2010) argues that example (1) The creampuff didn’t even show up has a referential function, like metonymy, but is, in fact, an instance of metaphor. Analogously, in (2) Ann has her mother’s eyes, Warren (1999) argues the relationship between the inherited characteristic is motivated by both perceptual similarity and conceptual contiguity. What these two examples reveal is the following: First, metaphor can exhibit symptoms normally attributed to metonymy, and second, there appears not to always be a clear distinction between where metonymy ends and metaphor begins. This observation leads to a number of outstanding questions. First, is metonymy in fact a unified phenomenon? Second, if not, how are metonymies motivated? Third, how is metonymy related to other figurative phenomena, especially metaphor? I argue that metonymy, while constituting a unified phenomenon, nevertheless exhibits variation. In point of fact, I claim that examples (1) and (2) amount to distinct types of metonymy, which lie on a continuum. To answer the second question, I examine the nature of metonymic compositionality. I do so to show how metonymic linguistic ‘vehicles’ interface with the (nonlinguistic) conceptual level in the course of figurative language understanding. Finally, I explore the relationship between metaphor and metonymy. I argue that they are related in terms of occupying a continuum with different linguistic expressions and, on occasion, exhibiting symptoms of bot

Biochemical evidence for the interaction of regulatory subunit of cAMP-dependent protein kinase with IDA (Inter-DFG-APE) region of catalytic subunit

AbstractTo explore the structural basis required for the holoenzyme formation of cAMP-dependent protein kinase, we have prepared rabbit anti-peptide antibodies that can block the holoenzyme formation without affecting the catalytic activity of the enzyme. The antibodies were raised against a specific site in the catalytic (C)-subunit, termed IDA (Inter-DFG-APE) region, which lies between the kinase subdomains VII and VIII. Although the C-subunit immunoprecipitated with anti-IDA antibodies could not form a stable complex with regulatory (R)-subunit, it was still susceptible to inhibition by the R-subunit or by PKI, a specific inhibitor peptide containing a pseudosubstrate site. These results indicate that there exists an IDA regionmediated interaction between the R- and C-subunits, which is distinct from that mediated through the substrate site and substrate binding site. In accordance with this idea, association of synthetic IDA peptides with the R-subunit was directly demonstrated by resonance mirror analysis. The calculated association constants of IDA peptides were high enough to suggest a possible involvement of the IDA region in the initial step of holoenzyme formation

Isolation and molecular characterization of multidrug-resistant Gram-negative bacteria from imported flamingos in Japan

Imported animals, especially those from developing countries, may constitute a potential hazard to native animals and to public health. In this study, a new flock of lesser flamingos imported from Tanzania to Hiroshima Zoological Park were screened for multidrug-resistant Gram-negative bacteria, integrons and antimicrobial resistance genes. Thirty-seven Gram-negative bacterial isolates were obtained from the flamingos. Seven isolates (18.9%) showed multidrug resistance phenotypes, the most common being against: ampicillin, streptomycin, tetracycline, trimethoprim/sulfamethoxazole and nalidixic acid. Molecular analyses identified class 1 and class 2 integrons, β-lactamase-encoding genes, blaTEM-1 and blaCTX-M-2 and the plasmid-mediated quinolone resistance genes, qnrS and qnrB. This study highlights the role of animal importation in the dissemination of multidrug-resistant bacteria, integrons and antimicrobial resistance genes from one country to another

Cold-shock eliminates female nucleus in fertilized eggs to induce androgenesis in the loach (Misgurnus anguillicaudatus), a teleost fish

<p>Abstract</p> <p>Background</p> <p>Androgenesis (all-male inheritance) is generally induced by means of irradiating the eggs to inactivate the maternal genome, followed by fertilization with normal sperm. In fish, the conventional technique for induced androgenesis has been applied for rapid fixation to traits, recovery of cryopreserved genotypes, sex-control, etc. A new method of androgenesis that eliminates the need to irradiate the egg was proposed using the loach, <it>Misgurnus anguillicaudatus </it>(a teleost fish).</p> <p>Results</p> <p>When the eggs of wild-type females were fertilized with sperm of albino or orange phenotype males and cold-shocked at 0 to 3°C for 60 min duration just after fertilization, generally more than 30% (with a peak of 100%) of the hatched progeny were androgenotes. While a few of them were the normal diploid, most of them turned out to be abnormal haploid. All-male inheritance was verified by the expression of the recessive color trait (albino or orange) and microsatellite genotypes comprising only paternally derived alleles. Nuclear behavior after the cold-shock treatment was traced by microscopic observation of DAPI (4'6-diamidino-2-phenylindole)-stained samples and hematoxylin-eosin stained histological sections, and the extrusion of egg (maternal) nucleus was observed in eggs treated in the optimum timing.</p> <p>Conclusion</p> <p>In this paper, we demonstrate that cold-shock treatment (at 0 and 3°C) of loach eggs for 60 min just after fertilization successfully induces androgenetic haploid development. The most likely mechanism of cold-shock induced androgenesis is an elimination of the egg nucleus together along with the second polar body and subsequent development of a decondensed sperm nucleus or male pronucleus.</p

Salmon DNA Accelerates Bone Regeneration by Inducing Osteoblast Migration.

The initial step of bone regeneration requires the migration of osteogenic cells to defective sites. Our previous studies suggest that a salmon DNA-based scaffold can promote the bone regeneration of calvarial defects in rats. We speculate that the salmon DNA may possess osteoinductive properties, including the homing of migrating osteogenic cells. In the present study, we investigated the influence of the salmon DNA on osteoblastic differentiation and induction of osteoblast migration using MG63 cells (human preosteoblasts) in vitro. Moreover, we analyzed the bone regeneration of a critical-sized in vivo calvarial bone defect (CSD) model in rats. The salmon DNA enhanced both mRNA and protein expression of the osteogenesis-related factors, runt-related transcription factor 2 (Runx2), alkaline phosphatase, and osterix (OSX) in the MG63 cells, compared with the cultivation using osteogenic induction medium alone. From the histochemical and immunohistochemical assays using frozen sections of the bone defects from animals that were implanted with DNA disks, many cells were found to express aldehyde dehydrogenase 1, one of the markers for mesenchymal stem cells. In addition, OSX was observed in the replaced connective tissue of the bone defects. These findings indicate that the DNA induced the migration and accumulation of osteogenic cells to the regenerative tissue. Furthermore, an in vitro transwell migration assay showed that the addition of DNA enhanced an induction of osteoblast migration, compared with the medium alone. The implantation of the DNA disks promoted bone regeneration in the CSD of rats, compared with that of collagen disks. These results indicate that the salmon DNA enhanced osteoblastic differentiation and induction of migration, resulting in the facilitation of bone regeneration.福岡歯科大学2016年