Lip incompetence and myofunctional therapy

Lip incompetence, which is a state in which the upper and lower lips are constantly apart, is thought to induce mouth breathing that may result in the development of gingivitis and periodontal disease. In the orthodontic field, lip incompetence has major problems for diagnosis, when determining the treatment goal and at the time of retention. We have been performing studies on lip incompetence and have obtained the following results : (1) it is possible to predict to some extent the state of lip closure during sleep by examination only in an awake state, (2) anterior teeth are positioned forward in individuals with lip incompetence, and (3) a training method called Button Pull is effective as a myofunctional therapy for improving lip incompetence, but there remains a need to clarify the background

ファジィニューラルネットワークを用いた手書き曲線同定法FSCIの学習最適化

This paper demonstrates effectiveness of training of Fuzzy Spline Curve Identifier (FSCI) using a fuzzy neural network. FSCI was proposed as a primitive curve identification system designed to establish a general-purpose freehand interface for computer aided drawing (CAD) systems. It succeeded in distinguishing a freehand drawing into seven kinds of primitive curves which are indispensable for use in CAD. The key was the introduction of a fuzzy reasoning which embodied a strategy to try to find the simplest primitive curves in drawing. A trainable version of FSCI was then proposed, by introducing a structured fuzzy neural network, in order that it would acquire learning ability to adapt itself to individual drawing manner. This paper sets up some experiment on FSCI and demonstrates the effectiveness of the training by evaluating curve class recognition rates. Furthermore, through some considerations on a concrete example of the training, it shows that the introduced fuzzy neural network is informative for us to analyze users\u27 drawing manner and also the identification characteristics of FSCI.特集 : 「産業におけるソフトコンピューティングに関する国際会議\u2799」発表論文選

Comparison between Serum and Saliva Biochemical Constituents in Dairy Cows during Lactation and Dry Period

The present study was undertaken to compare serum and salivary biochemical constituents during lactation and dry period in dairy cows. Also, the present study evaluated for the first time the salivary biochemical constituents in dairy cows. The study was carried out using 45 healthy multiparous Holstein cows maintained in dairy farms located in Morioka city (Iwate prefecture, Japan). Cows were classified into groups based on the month of lactation. Serum, saliva and milk samples were collected and analyzed. Data were statistically analyzed and the variation in serum and salivary biochemical constituents during lactation and dry period were discussed. From the present study, it could be concluded that the 1st month of lactation has the highest levels for serum free fatty acids (FFA), β- Hydroxy butyric acid (BHBA) and aceto Acetic acid (ACAC). The dry period has the highest serum glucose level and the lowest serum FFA, BHBA and aspartate aminotransferase levels. Both serum and salivary FFA showed the highest value during the 1st month of lactation. Saliva contains a high level of gamma glutamyl transferase. The level of ammonia in saliva is higher than its serum level during all months of lactation and dry period. Most of the biochemical constituents in saliva change in different way from serum during lactation and dry period. Milk protein/fat ratio of 0.7 may be not indicative for subclinical ketosis

Involvement of interleukin-8 in dialysis-related arthritis

Involvement of interleukin-8 in dialysis-related arthritis. To elucidate the role of interleukin (IL)-8, a chemotactic factor for neutrophils, in dialysis-related arthritis (DRA) of patients on long-term hemodialysis, the concentration of IL-8 was measured in the synovial fluids of DRA patients with acute arthralgia and joint swelling, and was compared with those in patients with rheumatoid arthritis (RA) and patients with osteoarthritis (OA). We noted a marked elevation of IL-8 in the joint fluids of patients with DRA and RA as compared with OA. Furthermore, to determine the role of IL-8 in synovitis, we examined the in vivo effect of intra-articular injection of human recombinant IL-8 on leukocyte infiltration into the joint space of rabbits. A single injection of IL-8 to the joints of rabbits induced rapid infiltration of neutrophils into the joint space and synovial tissues, which reached a maximum in four hours. The oral administration of indometacin farnesil (a prodrug that is converted to indomethacin after intestinal absorption) before the injection of IL-8 alleviated the infiltration of neutrophils. When human synovial cells were incubated with tumor necrosis factor (TNF)-α, the expression of IL-8 mRNA and IL-8 production in the cultured synovial cells were increased. The TNF-α-stimulated expression of IL-8 mRNA and IL-8 production in the cultured synovial cells were markedly inhibited by dexamethasone. In conclusion, IL-8 levels were markedly elevated in the joint fluids of patients with DRA. Interleukin-8 released from synovial cells may be an important factor to induce acute inflammation in DRA. Dexamethasone and indomethacin may be effective for DRA by inhibiting the production and chemotactic actions of IL-8, respectively

Suzaku Observation of the Metallicity in the Interstellar Medium of NGC 4258

The Suzaku X-ray satellite observed the nearby spiral galaxy NGC 4258 for a total good exposure time of 100 ks. We present an analysis of the Suzaku XIS data, in which we confirm that the 0.5--2 keV spectra of the interstellar medium (ISM) are well-represented by a two-temperature model. The cool and hot ISM temperatures are 0.23+-0.02 and 0.59 +-0.01 keV, respectively. Suzaku's excellent spectral sensitivity enables us to measure the metal abundances of O, Ne, Mg, Si and Fe of the ISM for the first time. The resultant abundance pattern of O, Mg, Si, and Fe is consistent with that of the new solar abundance table of Lodders (2003), rather than Anders & Grevesse (1989). This suggests that the metal enrichment processes of NGC 4258 and of our Galaxy are similar.Comment: 9 pages, 4 figure