Erosion wear of glass fibre reinforced vinyl ester

This study evaluates the slurry-erosion wear of glass fibre reinforced vinyl ester composites (VE-FRP) using a high speed slurry-pot type wear tester. The wear rates of VE-FRP were compared using different abrasives, namely quartz, chromite, copper ore, zinc concentrate, and tailings. Furthermore, the effect of abrasive particle size and slurry concentration on the VE-FRP wear was studied. The erosion wear results of VE-FRP were compared to natural rubber (NR) and bromobutyl rubber (BIIR) as well as to few common thermoplastics, such as polypropylene (PP) and polyvinyl chloride (PVC). Moreover, the failure characteristics of VE-FRP were analyzed. The results demonstrated that coarse quartz produced the largest wear rates on VE-FRP samples, while the zinc concentrate showed the lowest wear. Minor changes in the abrasive particle size had no effect on the wear results, only when the particle size was markedly raised, the wear started to increase. When comparing the wear rates of different materials, it was concluded that with all abrasive types, tested rubbers and thermoplastics had lower wear rates than VE-FRP

Exploring the role of fibre sizing to the fatigue of glass fibre composites using a novel, reliable micro-fatigue test

Single fibre micro-composite tests are among the most reliable methods for characterising the fibre–matrix interphase. To improve their versatility, this study utilises a well-characterised microbond setup in a cyclic loading case to create a so-called micro-fatigue test. The surface of the fibres is controlled to create two distinctive interphase types: a clean glass fibre surface, and a model sizing. The sizing improved the average interfacial performance in all tested cases, but the role of the sizing was most prominent in the fatigue lifetime of the microdroplet samples. Finite element analysis was used to evaluate the strain-rate dependency and heating related to the plastic deformation of the microdroplet samples in cyclic loading and predicted a well behaving experimental setup. The method offers a promising pathway for further studies on interfacial fatigue and the role of sizing in it.publishedVersionPeer reviewe

Antibacterial polymer fibres by rosin compounding and melt-spinning

The antibacterial features of natural pine/spruce rosin are well established, yet the functionality in various thermoplastics has not been surveyed. This work focuses on the processing of industrial grade purified rosin mixed with polyethylene (PE), polypropylene (PP), polylactic acid (PLA), polyamide (PA) and corn starch based biopolymer (CS). Homopolymer masterbatches were extrusion-compounded and melt-spun to form fibres for a wide range of products, such as filters, reinforcements, clothing and medical textiles. Due to the versatile chemical structure of rosin, it was observed compatible with all the selected polymers. In general, the rosin-blended systems were shear-thinning in a molten condition. The doped fibres spun of PE and PP indicated adequate melt-spinning capability and proper mechanical properties in terms of ultimate strength and Young's modulus. The antibacterial response was found dependent on the selected polymer. Especially PE with a 10 wt% rosin content showed significant antibacterial effects against Escherichia coli DH5α and Staphylococcus aureus ATCC 12598 when analysed in the Ringer's solution for 24 h.Peer reviewe

Disulfide relays and phosphorylative cascades: Partners in redox-mediated signaling pathways

Modifications of specific amino-acid residues of proteins are fundamental in order to modulate different signaling processes among which the cascade of phosphorylation represents the most effective example. Recently, also, the modification of the redox state of cysteine residues of certain proteins, which is a widespread mechanism in the regulation of protein function, has been proposed to be involved in signaling pathways. Growing evidence shows that some transcription factors could be modulated by both oxidation and phosphorylation. In particular, the pathways regulated by the mitogen activated protein (MAP) kinases represent well-established examples of the cross talk between redox-mediated signaling and phosphorylative cascades. This review will compare the two modes of signal transduction and propose an evolutionary model of a partnership of the two mechanisms in the eukaryotic cell, with redox-mediated signals being more specific and ancestral and phosphorylative signals being more diffuse but predominant in signal propagation. © 2005 Nature Publishing Group All rights reserved

Functional imaging studies of cognition using 99mTc-HMPAO SPECT: empirical validation using the n-back working memory paradigm

{Purpose} Functional activation protocols are widely applied for the study of brain-cognition relations. Only few take advantage of the intrinsic characteristics of SPECT, particularly those allowing cognitive assessment outside of the camera, in settings close to the standard clinical or laboratory ones. The purpose of the study was to assess the feasibility of a split-dose activation protocol with 99mTc-HMPAO using low irradiation dose. {Materials and methods} A two-scans protocol was applied to 12 healthy young volunteers using 270 MBq of 99mTc-HMPAO per scan, with each image associated to a particular experimental condition of the verbal {n}-back working memory task (0-back, 2-back). Subtraction method was used to identify regional brain activity related to the task. {Results} Voxel-wise statistical analysis showed left lateralized activity associated with the 2-back task, compared to the 0-back task. Activated regions, mainly prefrontal and parietal, were similar to those observed in previous fMRI and 15O-PET studies. {Conclusion} The results support the use of 99mTc-HMPAO SPECT for the investigation of brain-cognition relations and demonstrate the feasibility of optimal quality images despite low radiopharmaceutical doses. The findings also acknowledge the use of HMPAO as a radioligand to capture neuro-energetic modulations linked to cognitive activity. They encourage extending the application of the described activation protocol to clinical populations