Beam Propagation Through Atmospheric Turbulence Using an Altitude-Dependent Structure Profile with Non-Uniformly Distributed Phase Screens

For free-space optical communication systems, numerical wave optics simulations provide a useful technique for modeling turbulence-induced beam degradation when the analytical theory is insufficient for characterizing the atmospheric channel. Motivated by such applications we use a split-step method modeling the turbulence as a series of random phase screens using the Hufnagel-Valley turbulence profile. We employ a space-to-ground case study to examine the irradiance and phase statistics for uniformly and non-uniformly located screens and find better agreement with theory using a non-uniform discretization minimizing the contribution of each screen to the total scintillation. In this poster, we summarize the method and the results of the case study including a comparison to layered models used in astronomical imaging applications

Beam Propagation Through Atmospheric Turbulence Using an Altitude-Dependent Structure Profile with Non-Uniformly Distributed Phase Screens

Modeling the effects of atmospheric turbulence on optical beam propagation is a key element in the design and analysis of free-space optical communication systems. Numerical wave optics simulations provide a particularly useful technique for understanding the degradation of the optical field in the receiver plane when the analytical theory is insufficient for characterizing the atmospheric channel. Motivated by such an application, we use a split-step method modeling the turbulence along the propagation path as a series of thin random phase screens with modified von Karman refractive index statistics using the Hufnagel-Valley turbulence profile to determine the effective structure constant for each screen. In this work, we employ a space-to-ground case study to examine the irradiance and phase statistics for both uniformly and non-uniformly spaced screens along the propagation path and compare to analytical results. We find that better agreement with the analytical theory is obtained using a non-uniform spacing with the effective structure constant for each screen chosen to minimize its contribution to the scintillation in the receiver plane. We evaluate this method as a flexible alternative to other standard layered models used in astronomical imaging applications

Measurements of few-mode fiber photonic lanterns in emulated atmospheric conditions for a low earth orbit space to ground optical communication receiver application

Photonic lanterns are being evaluated as a component of a scalable photon counting real-time optical ground receiver for space-to-ground photon-starved communication applications. The function of the lantern as a component of a receiver is to efficiently couple and deliver light from the atmospherically distorted focal spot formed behind a telescope to multiple small-core fiber-coupled single-element super-conducting nanowire detectors. This architecture solution is being compared to a multimode fiber coupled to a multi-element detector array. This paper presents a set of measurements that begins this comparison. This first set of measurements are a comparison of the throughput coupling loss at emulated atmospheric conditions for the case of a 60 cm diameter telescope receiving light from a low earth orbit satellite. The atmospheric conditions are numerically simulated at a range of turbulence levels using a beam propagation method and are physically emulated with a spatial light modulator. The results show that for the same number of output legs as the single-mode fiber lantern, the few-mode fiber lantern increases the power throughput up to 3.92 dB at the worst emulated atmospheric conditions tested of D/r(sub 0)=8.6. Furthermore, the coupling loss of the few-mode fiber lantern approaches the capability of a 30 micron graded index multimode fiber chosen for coupling to a 16 element detector array

seasonal variation of essential oil in rosmarinus officinalis leaves in sardinia

Rosmarinus officinalis L. is an aromatic plant belonging to the Lamiaceae family widely distributed in the Mediterranean area. The interest on this species is related to the multiple uses of the plant as a food ingredient, in the pharmaceutical and cosmetic industries. The chemical composition of essential oil (EO) from 5 accessions of R. officinalis L., collected monthly through a full year in Sardinia, has been studied by gas chromatography (GC) and GC-mass spectrometry technique. The EO ranged from 0.29% to 0.89%. The qualitative determinations revealed the presence of 27 compounds belonging to 6 chemical groups (hydrocarbon monoterpene, alcohols, aldehydes, ketones, esters, hydrocarbon sesquiterpene). Overall the GC-flame ionization detector analysis showed the presence of 7 major compounds: α-pinene (26%-28%), camphene (5%-8%), 1,8-cineole (15%-25%), borneol (5%-11%), camphor (3%-12%), verbenone (6%-15%), and bornyl acetate (4%-7%). Chromatographic data were also subjected to a chemometric approach that evidenced discrimination of the samples according to the site of collection

Ethnic and racial differences in Asian populations with ion channelopathies associated with sudden cardiac death

Cardiovascular diseases are associated with several morbidities and are the most common cause of worldwide disease-related fatalities. Studies show that treatment and outcome-related differences for cardiovascular diseases disproportionately affect minorities in the United States. The emergence of ethnic and racial differences in sudden cardiac death (SCD) and related ion channelopathies complicates cardiovascular disease prevention, diagnosis, management, prognosis, and treatment objectives for patients and physicians alike. This review compiles and synthesizes current research in cardiac ion channelopathies and genetic disorders in Asian populations, an underrepresented population in cardiovascular literature. We first present a brief introduction to SCD, noting relevant observations and statistics from around the world, including Asian populations. We then examined existing differences between Asian and White populations in research, treatment, and outcomes related to cardiac ion channelopathies and SCD, showing progression in thought and research over time for each ion channelopathy. The review also identifies research that explored phenotypic abnormalities, device usage, and risk of death in Asian patients. We touch upon the unique genetic risk factors in Asian populations that lead to cardiac ion channelopathies and SCD while comparing them to White and Western populations, particularly in the United States, where Asians comprise approximately 7% of the total population. We also propose potential solutions such as improving early genetic screening, addressing barriers affecting access to medical care and device utilization, physician training, and patient education on risks

Pathophysiology of Cav1.3 L-type calcium channels in the heart

Ca2+ plays a crucial role in excitation-contraction coupling in cardiac myocytes. Dysfunctional Ca2+ regulation alters the force of contraction and causes cardiac arrhythmias. Ca2+ entry into cardiomyocytes is mediated mainly through L-type Ca2+ channels, leading to the subsequent Ca2+ release from the sarcoplasmic reticulum. L-type Ca2+ channels are composed of the conventional Cav1.2, ubiquitously expressed in all heart chambers, and the developmentally regulated Cav1.3, exclusively expressed in the atria, sinoatrial node, and atrioventricular node in the adult heart. As such, Cav1.3 is implicated in the pathogenesis of sinoatrial and atrioventricular node dysfunction as well as atrial fibrillation. More recently, Cav1.3 de novo expression was suggested in heart failure. Here, we review the functional role, expression levels, and regulation of Cav1.3 in the heart, including in the context of cardiac diseases. We believe that the elucidation of the functional and molecular pathways regulating Cav1.3 in the heart will assist in developing novel targeted therapeutic interventions for the aforementioned arrhythmias

Measurements of Few-Mode Fiber Photonic Lanterns in Emulated Atmospheric Conditions for a Low Earth Orbit Space to Ground Optical Communication Receiver Application

Photonic lanterns are being evaluated as a component of a scalable photon counting real-time optical ground receiver for space-to-ground photon-starved communication applications. The function of the lantern as a component of a receiver is to efficiently couple and deliver light from the atmospherically distorted focal spot formed behind a telescope to multiple small-core fiber-coupled single-element super-conducting nanowire detectors. This architecture solution is being compared to a multimode fiber coupled to a multi-element detector array. This paper presents a set of measurements that begins this comparison. This first set of measurements are a comparison of the throughput coupling loss at emulated atmospheric conditions for the case of a 60 cm diameter telescope receiving light from a low earth orbit satellite. The atmospheric conditions are numerically simulated at a range of turbulence levels using a beam propagation method and are physically emulated with a spatial light modulator. The results show that for the same number of output legs as the single-mode fiber lantern, the few mode fiber lantern increases the power throughput up to 3.92 dB at the worst emulated atmospheric conditions tested of D/r0=8.6. Furthermore, the coupling loss of the few mode fiber lantern approaches the capability of a 30 micron graded index multimode fiber chosen for coupling to a 16 element detector array

A Baker\u27s Dozen of Top Antimicrobial Stewardship Intervention Publications in 2017

With an increasing number of antimicrobial stewardship-related articles published each year, attempting to stay current is challenging. The Southeastern Research Group Endeavor (SERGE-45) identified antimicrobial stewardship-related peer-reviewed literature that detailed an actionable intervention for 2017. The top 13 publications were selected using a modified Delphi technique. These manuscripts were reviewed to highlight the actionable intervention used by antimicrobial stewardship programs to provide key stewardship literature for training and teaching and identify potential intervention opportunities within their institutions

A Baker’s dozen of top antimicrobial stewardship intervention publications in 2019

© The Author(s) 2020. Staying current on literature related to antimicrobial stewardship can be challenging given the ever-increasing number of published articles. The Southeastern Research Group Endeavor (SERGE-45) identified antimicrobial stewardship–related peer-reviewed literature that detailed an actionable intervention for 2019. The top 13 publications were selected using a modified Delphi technique. These manuscripts were reviewed to highlight the actionable intervention used by antimicrobial stewardship programs to provide key stewardship literature for teaching and training and to identify potential intervention opportunities within one’s institution

A Baker’s Dozen of Top Antimicrobial Stewardship Intervention Publications in 2019

Staying current on literature related to antimicrobial stewardship can be challenging given the ever-increasing number of published articles. The Southeastern Research Group Endeavor (SERGE-45) identified antimicrobial stewardship–related peer-reviewed literature that detailed an actionable intervention for 2019. The top 13 publications were selected using a modified Delphi technique. These manuscripts were reviewed to highlight the actionable intervention used by antimicrobial stewardship programs to provide key stewardship literature for teaching and training and to identify potential intervention opportunities within one’s institution