1,822 research outputs found

    Desenvolvimento de uma interface gráfica de site de e-commerce para um negócio digital através da metodologia Kansei

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    PCC (graduação) — Universidade Federal de Santa Catarina. Centro de Comunicação e Expressão. Design.A interface de um site de e-commerce é um fator crucial para construir uma relação entre vendedores e consumidores. Além de ser uma plataforma de venda, a interface também é um canal de comunicação e seus aspectos gráficos devem refletir a identidade e as estratégias do negócio digital que ela representa. Em vista disso, o presente trabalho tem como objetivo desenvolver uma interface de site de e-commerce no ramo de produtos promocionais customizáveis. A caracterização geral da pesquisa é de natureza aplicada, de tipo exploratória com abordagem mista, qualitativa e quantitativa. O projeto foi conduzido através da metodologia kansei, que se divide em quatro etapas: síntese do espécime (etapa 1); estruturação da checklist kansei (etapa 2); conceituação kansei e requisitos (etapa 3) e prototipagem e validação (etapa 4). Primeiramente, foi avaliado o contexto do projeto e o levantamento de trabalhos predecessores, realizados para a empresa Smerch.lab. Baseado nisso, criou-se um formulário que foi aplicado remotamente com voluntários para avaliar exemplares de interfaces gráficas diferentes com base em palavras-chaves da identidade da marca do site. Os valores médios das respostas foram cruzados com os valores de atributos dos elementos presentes em cada exemplar, gerando índices de correlação entre conceitos subjetivos avaliados por usuários comuns e dados objetivos mensuráveis. Os resultados obtidos na pesquisa mostram índices de correlação satisfatórios entre os conceitos da marca e os elementos projetáveis de uma interface, proporcionando diretrizes e requisitos para o desenvolvimento do protótipo final da interface gráfica que representa os conceitos da marca do negócio digital.The interface of an e-commerce website is an important factor for building a relationship between sellers and customers. Besides being a sales platform, the interface is also a communication channel, and its graphic features have to reflect the identity and the strategies of the digital business it represents. Considering that, this work aims to develop the interface of an e-commerce website in the field of customizable promotional products. This study was done as an applied and exploratory research, with a qualitative and quantitative mixed approach. The project was conducted through the kansei methodology, which is divided in four stages: Synthesizing Specimen (Stage 1); Establishment of Checklist (Stage 2); Determination of Kansei Concept and Requirement (Stage 3) and Prototyping/Testing (Stage 4). Firstly, the project context and previous works done for the Smerch.lab company were analysed. Based on that, an application form was created and applied remotely with volunteers, in order to evaluate graphic interface samples based on key-words related to the website’s brand identity. The values measured by the answers were cross-referenced with the values of the element’s traits present in each sample, creating correlation indexes between the subjective concepts rated by regular users and the measurable and objective data. The results obtained in the research showed satisfying correlation indexes between the brand concepts and the design elements of an interface, providing guidelines and requirements for the development of the final graphic interface prototype that represents the brand concepts of the digital business

    Bioelectrical Impedance Phase Angle: Utility in clinical practice

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    The choice of the best nutrition assessment method in hospitalized patients remains a challenge. The aim of this study was to review the use of phase angle (PA) in clinical practice. PA is a parameter obtained from bioelectrical impedance analysis, being a derived measure from the relationship between resistance and reactance. Because PA is dependent on body cell mass (BCM) and cell membrane functions, it has been considered a prognostic marker in several clinical conditions. BCM reflects the cellular components responsible for energy transfer and biochemical activity and is considered an excellent reference for expressing the rates of physiological processes, such as energy expenditure and proteolysis. Low PA values suggest cell death or decreased cell integrity, whereas higher PA values suggest a large amount of intact cell membranes, with a consequently better prognosis. The literature lacks studies determining PA reference values, which has prevented its use in routine clinical practice. Reference values are therefore necessary to properly evaluate possible deviations from the population mean

    Geologia, petrografia e geoquímica das associações leucograníticas arqueanas da área de Nova Canadá: Província Carajás

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    A área de Nova Canadá é marcada pela ocorrência expressiva de duas variedades de leucogranitos que, apesar de suas afinidades petrográficas, apresentam fortes contrastes geoquímicos. O Leucogranodiorito Nova Canadá é mais expressivo, sendo formado por leucogranodioritos e leucomonzogranitos de textura seriada e com moderado a fraco grau de recristalização, enquanto o Leucogranito Velha Canadá é mais enriquecido em quartzo, possui textura equigranular média a fina e é moderado a fortemente deformado. O comportamento geoquímico mostra que as rochas do Leucogranodiorito Nova Canadá são mais enriquecidas em Al2O3, CaO, Na2O, Ba, Sr e, na razão Sr/Y, têm padrão de elementos terras raras (ETR) levemente fracionado, com baixas razões (La/Yb)N e anomalias negativas de Eu ausentes ou discretas, enquanto aquelas do Leucogranito Velha Canadá apresentam conteúdos mais elevados de SiO2, Fe2O3, TiO2, K2O, Rb, HFSE (Zr, Y e Nb), das razões K2O/Na2O, FeOt/(FeOt+MgO), Ba/Sr e Rb/Sr, e são mais enriquecidas em ETR. Este último pode ser caracterizado ainda por: (i) baixas a moderadas razões (La/Yb)N com anomalias negativas de Eu acentuadas; (ii) moderadas a altas razões (La/Yb)N, com anomalias negativas de Eu discretas e padrão côncavo dos ETR pesados (ETRP). Tais contrastes geoquímicos sugerem origem distinta para essas unidades. O Leucogranodiorito Nova Canadá tem caráter menos evoluído e assinatura geoquímica híbrida entre manto e crosta (alto Ba-Sr), o que descarta sua origem unicamente por fusão crustal. Por sua vez, o Leucogranito Velha Canadá é mais evoluído e tem características de granitos stricto sensu, similares àqueles originados por anatexia crustal (alto-K). As afinidades geoquímicas entre o Leucogranodiorito Nova Canadá e os granitos da Suíte Guarantã do domínio mesoarqueano de Rio Maria sugerem que estes podem estar relacionados ao mesmo evento magmático que atuou naquele domínio, enquanto o Leucogranito Velha Canadá mostra afinidades com os vários granitos cálcio-alcalinos de alto-K que ocorrem na Província Carajás, porém sem uma clara correlação de idade. No entanto, o padrão deformacional deste último e as idades preliminares disponíveis associam o Leucogranito Velha Canadá ao Neoarqueano, o que poderia relacionar tal leucogranito aos mesmos eventos tectonomagmáticos que afetaram o domínio Canaã dos Carajás nesse período.Nova Canadá area is marked by the occurrence of two leucogranite varieties that, despite their petrographic affinities, show strong geochemical contrasts. Nova Canadá Leucogranodiorite is more expressive and composed of leucogranodiorites and leucomonzogranites of seriated texture from moderate to weak degree of recrystallization, while Velha Canadá Leucogranite is more enriched in modal quartz, has medium even-grained texture and is from moderately to strongly deformed. In addition, the geochemical behaviour shows that Nova Canadá Leucogranodiorite rocks are enriched in Al2O3, CaO, Na2O, Ba, Sr, have high Sr/Y ratios and slightly fractionated REE pattern, with low (La/Yb)N ratios and absence of negative Eu anomalies. In contrast, Velha Canadá Leucogranite shows higher contents of SiO2, Fe2O3, TiO2, K2O, Rb, HFSE (Zr, Y and Nb), and K2O/Na2O, FeOt/(FeOt+MgO), Ba/Sr and Rb/Sr ratios, being more enriched in REE and characterized by: (i) moderate to low (La/Yb)N ratios, with accentuated negative Eu anomalies; (ii) moderate to high (La/Yb)N ratios, discrete Eu anomalies and a concave shape with HREE patterns. Such geochemical contrasts suggest a distinct origin to these rocks. Nova Canadá Leucogranodiorite has less evolved characteristics related to mantle and crust geochemical signature (high Ba-Sr), while Velha Canadá Leucogranite has stricto sensu characteristics (high-K), being more evolved and similar to the granites originated by crustal anatexis. The geochemical affinities between Nova Canadá Leucogranodiorite and the rocks of Guarantã Suite from Rio Maria Domain suggest that they could be related to the same magmatic event. Velha Canadá Leucogranite shows affinities with various high-K calc-alkaline granites of Carajás Province. Even without a clear chronological relation, its deformational pattern is typical from the Neoarchean, which could relate it to the same tectonomagmatic event that affected Canaã dos Carajás Domain in that period

    Short-term effects of glyphosate and Roundup Transorb® formulation on the cyanobacteria Synechococcus elongatus

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    Glyphosate is an active ingredient used in herbicide formulations worldwide. However, besides glyphosate, these formulations have other components to facilitate glyphosate absorption by plants. These include the surfactants such as polyoxyethylene amine (POEA) present in the Roundup Transorb® (RT) formulation. Glyphosate formulations are potentially more toxic to non-target organisms than the pure active ingredient. In this work, we evaluated the toxicity (72 h) of pure glyphosate and RT for the cyanobacterium Synechococcus elongatus, based on biomass growth and cell viability. The formulation proved more toxic than pure glyphosate for both parameters analysed, with an IC50 (Inhibition concentration mean) based on biomass measured by optical density (750 nm) that was sixty times lower. Cell viability was not as sensitive as the biomass because, of the few cells left in the culture, most were viable. This indicates that there is a variation in tolerance between the cyanobacteria present in the inoculum. Thus, cell viability may underestimate the results of glyphosate and RT toxicity and be useful only in low concentrations of exposure

    Ultrasonic vs Drill Implant Site Preparation: Post-Operative Pain Measurement Through VAS, Swelling and Crestal Bone Remodeling: A Randomized Clinical Study.

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    Background: Piezosurgery is a surgical procedure that is able to perform osteotomies by a micrometric and selective cut of the bone tissue. The objective of this investigation was to evaluate two different techniques; an ultrasonic device, and a drill approach for implant site preparation. Methods: A total of fifty patients were recruited for the randomized clinical trial to receive dental implants for fixed prosthetic restoration in the posterior mandible and were allotted to two groups. In Group A the implant site was prepared following a drilling technique, while in Group B the implant site was prepared using an ultrasonic device; moreover, the operative duration was recorded. Postoperative pain and swelling were evaluated at 1, 2, 4, and 6 days. The crestal bone resorption was measured at 3 months from implant placement by a three-dimensional tomography evaluation. Results: The findings suggest that osteotomies performed by an ultrasonic device cause less pain and swelling. On the other hand, the piezoelectric preparation was characterized by a significative increase in the operative time. No statistical differences in crestal bone resorption were evident in the two different approaches. Conclusions: According to the outcome of the study, ultrasonic implant bed preparation can be used with success in implantology and could be considered a suitable alternative to traditional drilling techniques for dental fixture placement

    Does the coronary disease increase the hospital mortality in patients with aortic stenosis undergoing valve replacement?

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    OBJETIVOS: Com o aumento da expectativa de vida nas últimas décadas, tem-se um aumento concomitante da prevalência da estenose aórtica degenerativa e da doença aterosclerótica arterial coronária. O presente estudo visa avaliar a influência da doença aterosclerótica arterial coronária crítica em pacientes portadores de estenose aórtica submetidos ao implante isolado de prótese valvar ou combinado à revascularização do miocárdio. MÉTODOS: No período de janeiro de 2001 a março de 2006, foram analisados 448 pacientes submetidos ao implante isolado de prótese valvar aórtica (Grupo I) e 167 pacientes submetidos à substituição valvar aórtica combinada à revascularização do miocárdio (Grupo II). As variáveis pré e intra-operatórias eleitas para análise foram: sexo, idade, índice de massa corpórea, acidente vascular cerebral, diabete melito, doença pulmonar obstrutiva crônica, febre reumática, hipertensão arterial sistêmica, endocardite, infarto agudo do miocárdio e tabagismo, fração de ejeção do ventrículo esquerdo, doença aterosclerótica arterial coronária crítica, fibrilação atrial crônica, operação valvar aórtica prévia (conservadora), classe funcional de insuficiência cardíaca congestiva, valor sérico de creatinina, colesterol total, tamanho da prótese utilizada, extensão e número de anastomoses distais da revascularização do miocárdio realizada, tempos de circulação extracorpórea de pinçamento aórtico. No estudo estatístico empregou-se análise univariada multivariada. RESULTADOS: A mortalidade hospitalar foi 14,3% (64 óbitos) no Grupo I, sendo 14,5% (58 óbitos) nos pacientes sem doença aterosclerótica arterial coronária crítica associada (Grupo IB) e 12,8% (6 óbitos) nos que apresentavam essa associação (Grupo IA). A mortalidade hospitalar no Grupo II foi 17,6% (29 óbitos), sendo 16,1% (20 óbitos) nos pacientes submetidos à substituição valvar aórtica combinada à revascularização completa do miocárdio (Grupo IIA) e 20,9% (nove óbitos) nos com revascularização incompleta do miocárdio (Grupo IIB). CONCLUSÕES: Nos pacientes submetidos à substituição valvar aórtica isolada, a presença de doença aterosclerótica arterial coronária crítica associada, em pelo menos duas artérias, influenciou a mortalidade hospitalar. Nos pacientes submetidos ao tratamento cirúrgico combinado, o número de artérias coronárias com doença aterosclerótica crítica e a extensão da revascularização do miocárdio (RM completa ou incompleta), não influenciaram a mortalidade hospitalar, mas a realização de mais de três anastomoses distais interferiu.OBJECTIVES: With the increase in life expectancy occurred in recent decades, it has been noted the concomitant increase in the prevalence of aortic stenosis and degenerative disease of atherosclerotic coronary artery. This study aims to evaluate the influence of atherosclerotic coronary artery disease in patients with critical aortic stenosis undergoing isolated or combined implant valve prosthesis and coronary artery by pass grafting. METHODS: In the period of January 2001 to March 2006, there were analyzed 448 patients undergoing isolated implant aortic valve prosthesis (Group I) and 167 patients undergoing aortic valve prosthesis implant combined with coronary artery bypass grafting (Group II). Pre- and intra-operative variables elected for analysis were: age, gender, body mass index, stroke, diabetes mellitus, chronic obstructive pulmonary disease, rheumatic fever, hypertension, endocarditis, acute myocardial infarction, smoking, Fraction of the left ventricular ejection, critical atherosclerotic coronary artery disease, chronic atrial fibrillation, aortic valve operation prior (conservative), functional class of congestive heart failure, value serum creatinine, total cholesterol, size of the prosthesis used, length and number of distal anastomoses held in myocardial revascularization, duration of cardiopulmonary bypass and aortic clamping time. The statistical study employed invariant and multivariate analysis. RESULTS: Hospital mortality was 14.3% (64 deaths) in Group I, and 14.5% (58 deaths) in patients with atherosclerotic coronary artery disease associated criticism (Group IB) and 12.8% (six deaths) in which had this association (Group IA). Hospital mortality in Group II was 17.6% (29 deaths), and 16.1% (20 deaths) in patients undergoing implantation of prosthetic aortic valve combined to complete myocardial revascularization (Group II) and 20.9% (nine deaths) in the myocardial revascularization with incomplete (Group IIB). CONCLUSIONS: In patients undergoing implant isolated from aortic valve prosthesis, the presence of atherosclerotic coronary artery disease associated critical in at least two arteries, influenced the hospital mortality. In patients undergoing surgical treatment combined the number of coronary arteries with critical atherosclerotic disease and extent of coronary artery bypass grafting (complete or incomplete), did not affect the hospital mortality, but the realization of more than three anastomoses in the distal myocardial revascularization interfered

    Pharmacopuncture Versus Acepromazine in Stress Responses of Horses During Road Transport

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    AbstractAcupuncture has been shown to have the beneficial effect of reducing stress responses in animals and humans. Pharmacopuncture is the injection of subclinical doses of drugs into acupoints to give therapeutic results without side effects. This study compared the effects of injecting the usual dose of acepromazine (ACP; 0.1 mg/kg, intramuscularly [I.M.]) with those of pharmacopuncture (1/10 ACP dose at the governing vessel 1 [GV 1] acupoint) on the stress responses of healthy horses undergoing road transport for 2.5 hours. Four different treatments were applied immediately before loading, with 8 animals/treatment: injection of saline or ACP (0.1 mg/kg, I.M.) at the base of the neck; and injection of saline or 1/10 ACP (0.01 mg/kg) at the GV 1 acupoint. The road transport increased heart rate (HR), respiratory rate, body temperature, and serum cortisol of the untreated horses (injected with saline at the base of the neck). Pharmacopuncture at GV 1 reduced the average HR and transport-induced increase in HR at unloading, without changing the other variables. On the other hand, ACP (0.1 mg/kg) produced significant sedation and reduced the transport-induced increase in respiratory rate but without preventing the stress-induced increase of cortisol. Other acupuncture points and drugs should be tested to verify the beneficial effect of this therapy to reduce stress in horses during road transport

    Prediction of new gene products and characterization of hypothetical proteins of Bifidobacterium breve DS15-17 In Silico / Predição de novos produtos gênicos e caracterização de proteínas hipotéticas de Bifidobacterium breve DS15-17 In Silico

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    The representation of the gene content of an organism is impacted by several factors, ranging from sampling to sequencing and then the genome assembly task. The genome assembly process can generate errors that are related to insufficient coverage in the data set, an inadequate assembly methodology, and finally, errors related to the limitation of the assembly software used. Thus, some genes remain unidentified both in complete and draft genomes, this incomplete gene knowledge impacts on several organisms, mainly of medical and industrial interest, such as Bifidobacterium breve, a Gram-positive bacterium, found in the gastrointestinal microbiota of mammals, including humans, and has beneficial probiotic activities. Therefore, the objective of this work is to identify the new gene products not represented in the genome of Bifidobacterium breve DS15-17 using the raw reads of this organism. The reads were produced from the sequencing with the Illumina MiSeq platform. PAN2HGENE software was used to identify new gene products. After the analysis, 44 new gene products were identified, 26 with described function and 18 hypothetical proteins. The hypothetical proteins identified were analyzed in the ProtoNet and Superfamily databases

    Planejamento digital e cirurgia guiada em reabilitação oral: relatório de caso

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    Digital planning of the prosthesis associated with surgical planning increased predictability, since surgical guides indicate the best place for implant installation, thus reducing the number of complications, and the CAD/CAM system provides predictability in the preparation of final restorations, according to the procedure previously planned. Our study reported a digital workflow used for the guided installation of two dental implants in regions 14 and 16, extraction of tooth 15 and installation of a fixed prothesis over implants. After anamnesis and clinical evaluation, intra- and extra-oral photographs of the patient were performed, molding the upper arch with polyvinylsiloxane (2-step putty/light-body technique) and requesting computed tomography. The plaster model obtained was sent to the laboratory and scanned. The generated file (STL) was used to create a diagnostic wax-up that was aligned to the tomography (in DICOM format), enabling the three-dimensional planning of the implants, which generated a partial printed surgical guide after approval of the dentist. After six months, the patient received the provisional fixed prosthesis printed in PMMA (polymethylmethacrylate) on an intermediate in PEEK (polyetheretherketone) aiming to condition an emergency profile to receive a definitive prosthesis two months later, with zirconia-milled infrastructure on a ti-base. The correct understanding of the operator about the steps of the digital workflow (diagnosis, prosthetic planning, surgical planning, guide preparation, temporary and final restorations) gives the operator improved predictability at the time of surgery as well as satisfactory aesthetic and functional result of definitive restorations.Planejamento digital de prótese associada a planejamento cirúrgico aumenta a previsibilidade devido às guias cirúrgicas que indicam o melhor local para instalação do implante, reduzindo o número de complicações, e o sistema CAD/CAM permite previsibilidade ao preparar as restaurações finais, de acordo com o procedimento planejado anteriormente. Nosso estudo relata um fluxo de trabalho digital usado para a instalação guiada de dois implantes dentários nas regiões 14 e 16, extração do dente 15 e instalação de prótese fixa no lugar de implantes. Após anamnese e avaliação clínica, fotografias intra e extraorais do paciente foram tiradas, moldando o arco superior usando polivinilsiloxano (técnicas da dupla mistura e reembasamento) e solicitando tomografia computadorizada. O modelo de gesso obtido foi enviado para o laboratório e escaneado. O arquivo gerado (STL) foi usado para criar um diagnostic wax-up alinhado à tomografia (em formato DICOM), permitindo o planejamento tridimensional dos implantes, o que gerou uma guia cirúrgica parcialmente impressa após aprovação pelo dentista. Após seis meses, o paciente recebeu uma prótese fixa provisória impressa com PMMA (polimetilmetacrilato) em um intermediário em PEEK (Poli(éter-éter-cetona)) para condicionar um perfil emergencial e receber uma prótese definitiva dois meses depois, incluindo infraestrutura de zircônia moída em uma base TI. O entendimento adequado do operador a respeito dos passos envolvidos no fluxo de trabalho digital (diagnóstico, planejamento de prótese, planejamento cirúrgico, preparação da guia, restaurações temporárias e finais) forneceu ao operador maior previsibilidade no momento da cirurgia e um resultado estético e funcional satisfatório para as restaurações definitivas
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