UTILIZAÇÃO DA HIDROXIAPATITA DE CÁLCIO E ÁCIDO HIALURÔNICO (HArmonyCaTM) COMO PREENCHEDOR FACIAL

The human being throughout history has always sought beauty, which is demonstrated through philosophy and art. Several areas of study have emerged with the aim of enabling men to achieve physical beauty, among them, Cosmetic Dentistry. Among the procedures offered by cosmetic dentistry, we can highlight fillers with hyaluronic acid and calcium hydroxyapatite, as they are responsible for restoring volume and skin support with immediate results and at the same time stimulating collagen in the long term. In this study, a clinical case using the HArmonyCaTM was reported. And in the end, it can be concluded that the use of HarmonyCATM, presented itself as an excellent alternative for patients who seek volumization and stimulation of facial collagen, proving to be effective in the harmonization and balance of facial structures.O ser humano ao longo da história sempre buscou o belo, sendo demonstrado por meio da filosofia e pela arte. Várias áreas de estudo surgiram com a finalidade de possibilitar ao homem alcançar a beleza física, dentre estas, a Odontologia Estética. Entre os procedimentos ofertados pela odontologia estética podemos destacar os preenchedores com ácido hialurônico e hidroxiapatita de cálcio, pois são responsáveis por devolver o volume e a sustentação da pele com resultados imediatos e ao mesmo tempo estimular colágeno a longo prazo. Neste estudo relatou-se um caso clínico utilizando-se o HArmonyCaTM. E ao final pode-se concluir que o uso do HarmonyCATM, apresentou-se como uma excelente alternativa para pacientes que procuram volumização e estimulação de colágeno da face, demonstrando-se eficaz na harmonização e equilíbrio das estruturas faciais

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost

Evaluación de la actividad antibacteriana y moduladora del extracto etanólico de Calotropis procera (Aiton) W.T. Aiton contra cepas bacterianas multirresistentes: Effecto Antibacteriano de C. Procera

The objective of this study was to evaluate the antibacterial and modulatory activities of ethanolic extract of Calotropis procera (Aiton) W.T. Aiton against resistant species. By microdilution method, the minimum inhibitory concentration (MIC) of the extract and modulation of the subinhibitory concentration MIC/8 to norfloxacine, gentamicin and imipenem against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. There was obtained 512 μg/mL to Pseudomonas aeruginosa. To Staphylo­coccus aureus, modulation showed synergism to norfloxacin and gentamicin, with imipenem against Pseudomonas aeruginosa and gentamicin against Escherichia coli. Based on these results, more studies are needed to test the antibacterial activity of the extract.El objetivo de este estudio fue evaluar la actividad antibacteriana y moduladora del extracto etanólico de Calotropis procera (Aiton) W.T. Aiton contra cepas multirresistentes de bacterias. Por el método de microdilución, fueron definidas la concentración inhibidora mínima (MIC) del extracto y la modulación con la concentración inhibidora CIM / 8 del extracto con norfloxacina, gentamicina e imipenem contra Staphylococcus aureus, Escherichia coli y Pseudomonas aeruginosa. Se obtuvo 512 μg/mL para Pseudomonas aeruginosa. Se descubrió sinergismo en el caso de Staphylococcus aureus, en la modulación con norfloxacina y gentamicina, mientras que con imipenem frente a Pseudomonas aeruginosa y con gentamicina para Escherichia coli. Con base en estos resultados, se necesitan más estudios para probar la actividad antibacteriana del extracto

Evaluación de la actividad antibacteriana y moduladora del extracto etanólico de Calotropis procera (Aiton) W.T. Aiton contra cepas bacterianas multirresistentes

El objetivo de este estudio fue evaluar la actividad antibacteriana y moduladora del extracto etanólico de Calotropis procera (Aiton) W.T. Aiton contra cepas multirresistentes de bacterias. Por el método de microdilución, fueron definidas la concentración inhibidora mínima (MIC) del extracto y la modulación con la concentración inhibidora CIM / 8 del extracto con norfloxacina, gentamicina e imipenem contra Staphylococcus aureus, Escherichia coli y Pseudomonas aeruginosa. Se obtuvo 512 μg/mL para g/mL para Pseudomonas aeruginosa. Se descubrió sinergismo en el caso de Staphylococcus aureus, en la modulación con norfloxacina y gentamicina, mientras que con imipenem frente a Pseudomonas aeruginosa y con gentamicina para Escherichia coli. Con base en estos resultados, se necesitan más estudios para probar la actividad antibacteriana del extracto.The objective of this study was to evaluate the antibacterial and modulatory activities of ethanolic extract of Calotropis procera (Aiton) W.T. Aiton against resistant species. By microdilution method, the minimum inhibitory concentration (MIC) of the extract and modulation of the subinhibitory concentration MIC/8 to norfloxacine, gentamicin and imipenem against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. There was obtained 512 μg/mL para g/mL to Pseudomonas aeruginosa. To Staphylococcus aureus, modulation showed synergism to norfloxacin and gentamicin, with imipenem against Pseudomonas aeruginosa and gentamicin against Escherichia coli. Based on these results, more studies are needed to test the antibacterial activity of the extract

Épocas de plantio e doses de silício no rendimento de alface tipo americana The influence of planting times and silicon doses on the yield of crisphead lettuce

Com o objetivo de avaliar a influência de épocas de plantio e doses de silício sobre o rendimento e qualidade pós-colheita da alface tipo americana, cv. Raider, foram conduzidos dois ensaios nos períodos de maio a agosto de 2002 (inverno) e novembro de 2002 a janeiro de 2003 (verão), no município de Três Pontas-MG. Utilizou-se o delineamento de blocos ao acaso em parcelas subdivididas, sendo as parcelas constituídas pelas épocas de plantio (inverno e verão) e as subparcelas pelas doses de silício (0,0; 0,9; 1,8; 2,7 e 3,6 L ha-1), com quatro repetições. A maior massa fresca total, comercial e circunferência da cabeça foram obtidas no plantio de inverno. Para os dados relativos às doses de silício ajustou-se modelo quadrático, pelo qual se estimaram as doses 2,0 e 2,7 L ha-1, como as que proporcionaram os maiores rendimentos de massa fresca total e comercial, respectivamente. Ajustou-se modelo quadrático com ponto de máxima circunferência para a dose de 2,1 L ha-1 de silício, que proporcionou circunferência de 40,1 cm. O plantio de inverno apresentou melhor conservação pós-colheita que o de verão, quando avaliado por uma escala de notas, aos 10 e 20 dias após a colheita. Para aplicação aos 20 dias após o transplante, evidenciou-se efeito quadrático onde a dose de 2,0 L ha-1 de silício promoveu a melhor conservação pós-colheita da alface.<br>The influence of planting times and silicon levels were evaluated on yield and post-harvest quality of crisphead lettuce, cv. Raider. Two trials were carried out in Três Pontas, Minas Gerais State, Brazil, from May to August of 2002 (winter season) and November to January of 2003 (summer season). A randomized complete block design of split-plots was used, with two planting times applied to the main plots (winter and summer season) and five silicon levels (0.0; 0.9; 1.8; 2.7 and 3.6 L ha-1) applied to the subplots in four replications. The highest total and commercial fresh mass and head circumference were obtained in the winter planting times. A quadratic model adjusted for silicon levels showed that 2.0 and 2.7 L ha-1 levels resulted in the highest yield of total and commercial fresh mass, respectively. A maximum circumference of 40.1 cm was obtained with 2.1 L ha-1 silicon, according to a quadratic model. The winter planting showed better post-harvest conservation than the summer planting when evaluated by a scale at 10 and 20 days after harvest. The application at 20 days after transplantation showed a quadratic effect where 2.0 L ha-1 silicon level promoted the best post-harvest conservation of crisphead lettuce