The Synergic Relationship Between Industry 4.0 and Lean Management: Best Practices from the Literature

Industry 4.0 promises to make manufacturing processes more efficient using modern technologies like cyber-physical systems, internet of things, cloud computing and big data analytics. Lean Management (LM) is one of the most widely applied business strategies in recent decades. Thus, implementing Industry 4.0 mostly means integrating technologies in companies that already operate according to LM. However, due to the novelty of the topic, research on how LM and Industry 4.0 can be integrated is still under development. This paper explores the synergic relationship between these two domains by identifying six examples of real cases that address LM-Industry 4.0 integration in the extant literature. The goal is to make explicit the best practices that are being implemented by six distinct industrial sectors such as automotive, paper, furniture, healthcare, apparel, and machine manufacturing.Fundação para a Ciência e Tecnologia (FCT) and C-MAST (Centre for Mechanical and Aerospace Science and Technologies), under project UIDB/00151/2020info:eu-repo/semantics/publishedVersio

Viscosity and density measurements on compressed liquid n-Tetradecane

Comunicação apresentada na "University of Technology", em Graz, Áustria de 3-8 de setembro de 2017FCT - Fundação para a Ciência e Tecnologiainfo:eu-repo/semantics/publishedVersio

On the viscosity and other properties of poly(Ethylene Glycol) 600

Poster da conferência realizada na "University of Technology", em Graz, Áustria de 3-8 de setembro de 2017info:eu-repo/semantics/publishedVersio

Quest for a reference standard for viscosity at high temperatures and high pressures

This communication is dedicated to give notice of the present situation concerning the proposal of tris(2-ethylhexyl) trimellitate (TOTM) to be a reference standard fluid for viscosity at high temperatures and high pressures. This proposal stems from an internal project of the International Association for Transport Properties (IATP). A general overview of the efforts carried out so far by the scientific community towards that objective will be made. This will be complemented by a description of its main characteristics that support its proposal. In particular, the present work is concerned with the determination of the shear dependence of the viscosity of TOTM. Moreover, new results for the density of TOTM at moderately high temperatures and pressures up to 70 MPa are presented.This work was supported by the Strategic Project PEstOE/QUI/UI0100/2013 funded by Fundação para a Ciência e a Tecnologia (FCT, Portugal).N/

Rhodium catalyzed hydroformylation of kaurane derivatives: A route to new diterpenes with potential bioactivity

Kaurenic and grandiflorenic acids are naturally occurring diterpenes whose biological activity has been described. Both acids contain an exocyclic methylenic double bond that allows further functionalization on their structure. In an attempt to expand the number of derivatives of these two natural products, we have undertaken a study on the hydroformylation of the methyl esters of the two acids and the trimethylsilyl ether of kaurenol. These substrates have been hydroformylated by using unmodified Rh catalysts, as well as Rh/PPh3 and Rh/tris-(o-t-butylphenyl)phosphite catalytic systems at 100 °C and 20 bar of CO/H2 (1:1). For the three substrates, the two Rh catalysts modified with P-donor ligands, produced high conversions and chemo- and regioselectivities in the diastereoisomeric pair of linear aldehydes. In all cases, the stereoselectivity observed is strongly dependent of the system used, being the most diastereoselective the least hindered unmodified Rh/CO catalyst. A correlation between the higher diastereoselectivity and the faster [beta]-elimination of the metal-alkyl intermediate observed in the unmodified system is discussed.http://www.sciencedirect.com/science/article/B6TF5-4RVMXFD-3/1/d27e671ad9e0b7fc325dfd0bdf413c7

Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies

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A multidisciplinary program of preparation for childbirth and motherhood: maternal anxiety and perinatal outcomes

Background: To study maternal anxiety and perinatal outcomes in pregnant women submitted to a Multidisciplinary Program for Childbirth and Motherhood Preparation (MPCM).Methods: This is a not randomized controlled trial on 67 nulliparous pregnant women divided into two groups according to participation (MPCM Group; n = 38) or not (Control Group; n = 29) in MPCM. the program consisted of 10 meetings (between the 18th and the 38th gestational week) during which educational, physiotherapeutic and interaction activities were developed. Anxiety was quantified at the beginning and at the end of the gestational period by the Trace-State Anxiety Inventory (STAI).Results: Initial maternal anxiety was equivalent between the groups. At the end of the gestational period, it was observed that anxiety levels increased in the Control Group and were maintained in the MPCM Group. A higher occurrence of vaginal deliveries (83.8%) and hospital discharge of three-day-older newborns (81.6%) as a result of MPCM was also significant. Levels of state-anxiety at the end of pregnancy showed a negative correlation with vaginal delivery, gestational age, birth weight and Apgar index at the first minute and positive correlation with the hospital period remaining of the newborns.Conclusion: in the study conditions, MPCM was associated with lower levels of maternal anxiety, a larger number of vaginal deliveries and shorter hospitalization time of newborns. It was not related to adverse perinatal outcomes.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Univ Estadual Paulista, Botucatu Sch Med, Dept Neurol Psychol & Psychiat, Botucatu, SP, BrazilUniv Estadual Paulista, Botucatu Sch Med, Dept Gynecol & Obstet, Botucatu, SP, BrazilUniv Sagrado Coracao, Dept Hlth Sci, Physiotherapy Sch, Bauru, BrazilSão Paulo Fed Univ Unifesp, Dept Hlth Sci, Phys Therapy Program, Santos, BrazilSão Paulo Fed Univ Unifesp, Dept Hlth Sci, Phys Therapy Program, Santos, BrazilWeb of Scienc