25 research outputs found

    A IMPORTÂNCIA DO INSTITUTO DO DIREITO DE SUPERFÍCIE PARA A FUNCIONALIZAÇÃO DA PROPRIEDADE

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    O Direito de Superfície é um instituto de aplicação ainda embrionária em nosso ordenamento jurídico pátrio, isto porque sua previsão é recente, tendo sido inserido pelo Estatuto da Cidade, conforme Lei 10.257 de 2001, e, posteriormente, pelo Código Civil de 2002. Inicialmente, neste artigo, discorreremos acerca do conceito e objeto do instituto do Direito de Superfície, em seguida, abordaremos acerca da previsão deste instituto em ambos os diplomas legais vigentes, discutindo se há um conflito normativo entre eles, e, por fim, demonstraremos a sua importância para a funcionalização da propriedade

    Impact of Arterial Stiffness on All-Cause Mortality in Patients Hospitalized With COVID-19 in Spain

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    Older age and cardiovascular comorbidities are well-known risk factors for all-cause mortality in patients with coronavirus disease 2019 (COVID-19). Hypertension and age are the 2 principal determinants of arterial stiffness (AS). This study aimed to estimate AS in patients with COVID-19 requiring hospitalization and analyze its association with all-cause in-hospital mortality. This observational, retrospective, multicenter cohort study analyzed 12 170 patients admitted to 150 Spanish centers included in the SEMI-COVID-19 Network. We compared AS, defined as pulse pressure ≥60 mm Hg, and clinical characteristics between survivors and nonsurvivors. Mean age was 67.5 (±16.1) years and 42.5% were women. Overall, 2606 (21.4%) subjects died. Admission systolic blood pressure (BP) <120 and ≥140 mm Hg was a predictor of higher all-cause mortality (23.5% and 22.8%, respectively, P<0.001), compared with systolic BP between 120 and 140 mm Hg (18.6%). The 4379 patients with AS (36.0%) were older and had higher systolic and lower diastolic BP. Multivariate analysis showed that AS and systolic BP <120 mm Hg significantly and independently predicted all-cause in-hospital mortality (adjusted odds ratio [ORadj]: 1.27, P=0.0001; ORadj: 1.48, P=0.0001, respectively) after adjusting for sex (males, ORadj: 1.6, P=0.0001), age tertiles (second and third tertiles, ORadj: 2.0 and 4.7, P=0.0001), Charlson Comorbidity Index (second and third tertiles, ORadj: 4.8 and 8.6, P=0.0001), heart failure, and previous and in-hospital antihypertensive treatment. Our data show that AS and admission systolic BP <120 mm Hg had independent prognostic value for all-cause mortality in patients with COVID-19 requiring hospitalization

    ABORDAGEM A ANSIEDADE: ESTRÁTÉGIAS DE MANEJO E BEM-ESTAR MENTAL

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    The purpose of this research is to develop practical, evidence-based interventions to prevent and treat anxiety, considering demographic differences and specific challenges. To achieve this objective, we conducted a narrative literature review in academic databases, such as PubMed, Scopus, SciELO, Virtual Health Library, Lilacs and Google Scholar. The inclusion criteria cover works published in the last 10 years, free of charge, available in full and related to the proposed theme. On the other hand, the exclusion criteria include works published outside the selected period, repeated, unrelated to the proposed theme and incomplete. In data analysis, 50 articles were read in full, in addition to consulting 2 websites to obtain epidemiological data. Of these, only 5 were included in the study. The theoretical framework was organized into distinct topics, providing a solid basis for the analysis of anxiety. These topics covered psychological theories that explore its origins and manifestations, biological factors that influence its development, and a variety of effective interventions in managing and treating this complex phenomenon. By approaching each topic separately, it was possible to examine in detail the multiple facets of anxiety , providing a clearer and more comprehensive view of this relevant topic. The research highlighted a growing concern about anxiety disorders, compounded by sociocultural pressures and contemporary challenges. This encompasses the incessant search for validation on social networks, as well as in the family and social spheres, generating increasing uncertainty in relation to social approval and the paradigms established in society.O propósito desta pesquisa é desenvolver intervenções práticas, embasadas em evidências, com o intuito de prevenir e tratar a ansiedade, considerando as diferenças demográficas e os desafios específicos. Para alcançar esse objetivo, conduzimos uma revisão narrativa de literatura em bases de dados acadêmicas, como PubMed, Scopus, SciELO, Biblioteca virtual de saúde, Lilacs e Google Scholar. Os critérios de inclusão abrangem trabalhos publicados nos últimos 10 anos, de acesso gratuito, disponíveis na íntegra e relacionados à temática proposta. Por outro lado, os critérios de exclusão compreendem trabalhos publicados fora do período selecionado, repetidos, não relacionados à temática proposta e incompletos.Na análise dos dados, foram lidos na íntegra 50 artigos, além de consultar 2 sites para obtenção de dados epidemiológicos. Destes, apenas 5 foram incluídos para compor o estudo. O referencial teórico foi organizado em tópicos distintos, proporcionando uma base sólida para a análise da ansiedade. Esses tópicos abordaram teorias psicológicas que exploram suas origens e manifestações, fatores biológicos que influenciam seu desenvolvimento, e uma variedade de intervenções eficazes na gestão e tratamento desse fenômeno complexo.Ao abordar cada tópico de forma separada, foi possível examinar detalhadamente as múltiplas facetas da ansiedade, proporcionando uma visão mais clara e abrangente deste tema relevante. A pesquisa destacou uma crescente inquietação em relação aos distúrbios de ansiedade, agravados por pressões socioculturais e desafios contemporâneos. Isso engloba a busca incessante por validação nas redes sociais, assim como nas esferas familiar e social, gerando uma crescente incerteza em relação à aprovação social e aos paradigmas estabelecidos na sociedade

    ¿Qué queda de mí?

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    Este libro es una reclamación a quienes hemos sido, somos o seremos docentes. A quienes no hemos respetado a las personas que se han puesto junto a nosotros y nosotras, confiando su bien más preciado: la libertad. Estas páginas denuncian cada vez que convertimos una visión en la visión, una emoción en la emoción, un saber en el saber, un comportamiento en el comportamiento. Es un grito contra la imposición, la normalización, la neutralización y la universalización de una perspectiva particular. Una pugna contra cada proceso que no se ha conectado con las vidas de los aprendices. Un texto colaborativo realizado por alumnado de Educación y Cambio Social en el Grado en Educación Infantil de la Universidad de Málaga y coordinado por Ignacio Calderón Almendros

    Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults

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    Background Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories. Methods We used data from 3663 population-based studies with 222 million participants that measured height and weight in representative samples of the general population. We used a Bayesian hierarchical model to estimate trends in the prevalence of different BMI categories, separately for adults (age ≥20 years) and school-aged children and adolescents (age 5–19 years), from 1990 to 2022 for 200 countries and territories. For adults, we report the individual and combined prevalence of underweight (BMI &lt;18·5 kg/m2) and obesity (BMI ≥30 kg/m2). For school&#x2;aged children and adolescents, we report thinness (BMI &lt;2 SD below the median of the WHO growth reference) and obesity (BMI &gt;2 SD above the median). Findings From 1990 to 2022, the combined prevalence of underweight and obesity in adults decreased in 11 countries (6%) for women and 17 (9%) for men with a posterior probability of at least 0·80 that the observed changes were true decreases. The combined prevalence increased in 162 countries (81%) for women and 140 countries (70%) for men with a posterior probability of at least 0·80. In 2022, the combined prevalence of underweight and obesity was highest in island nations in the Caribbean and Polynesia and Micronesia, and countries in the Middle East and north Africa. Obesity prevalence was higher than underweight with posterior probability of at least 0·80 in 177 countries (89%) for women and 145 (73%) for men in 2022, whereas the converse was true in 16 countries (8%) for women, and 39 (20%) for men. From 1990 to 2022, the combined prevalence of thinness and obesity decreased among girls in five countries (3%) and among boys in 15 countries (8%) with a posterior probability of at least 0·80, and increased among girls in 140 countries (70%) and boys in 137 countries (69%) with a posterior probability of at least 0·80. The countries with highest combined prevalence of thinness and obesity in school-aged children and adolescents in 2022 were in Polynesia and Micronesia and the Caribbean for both sexes, and Chile and Qatar for boys. Combined prevalence was also high in some countries in south Asia, such as India and Pakistan, where thinness remained prevalent despite having declined. In 2022, obesity in school-aged children and adolescents was more prevalent than thinness with a posterior probability of at least 0·80 among girls in 133 countries (67%) and boys in 125 countries (63%), whereas the converse was true in 35 countries (18%) and 42 countries (21%), respectively. In almost all countries for both adults and school-aged children and adolescents, the increases in double burden were driven by increases in obesity, and decreases in double burden by declining underweight or thinness. Interpretation The combined burden of underweight and obesity has increased in most countries, driven by an increase in obesity, while underweight and thinness remain prevalent in south Asia and parts of Africa. A healthy nutrition transition that enhances access to nutritious foods is needed to address the remaining burden of underweight while curbing and reversing the increase in obesit

    The James Webb Space Telescope Mission

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    Twenty-six years ago a small committee report, building on earlier studies, expounded a compelling and poetic vision for the future of astronomy, calling for an infrared-optimized space telescope with an aperture of at least 4m4m. With the support of their governments in the US, Europe, and Canada, 20,000 people realized that vision as the 6.5m6.5m James Webb Space Telescope. A generation of astronomers will celebrate their accomplishments for the life of the mission, potentially as long as 20 years, and beyond. This report and the scientific discoveries that follow are extended thank-you notes to the 20,000 team members. The telescope is working perfectly, with much better image quality than expected. In this and accompanying papers, we give a brief history, describe the observatory, outline its objectives and current observing program, and discuss the inventions and people who made it possible. We cite detailed reports on the design and the measured performance on orbit.Comment: Accepted by PASP for the special issue on The James Webb Space Telescope Overview, 29 pages, 4 figure

    Rationale, study design, and analysis plan of the Alveolar Recruitment for ARDS Trial (ART): Study protocol for a randomized controlled trial

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    Background: Acute respiratory distress syndrome (ARDS) is associated with high in-hospital mortality. Alveolar recruitment followed by ventilation at optimal titrated PEEP may reduce ventilator-induced lung injury and improve oxygenation in patients with ARDS, but the effects on mortality and other clinical outcomes remain unknown. This article reports the rationale, study design, and analysis plan of the Alveolar Recruitment for ARDS Trial (ART). Methods/Design: ART is a pragmatic, multicenter, randomized (concealed), controlled trial, which aims to determine if maximum stepwise alveolar recruitment associated with PEEP titration is able to increase 28-day survival in patients with ARDS compared to conventional treatment (ARDSNet strategy). We will enroll adult patients with ARDS of less than 72 h duration. The intervention group will receive an alveolar recruitment maneuver, with stepwise increases of PEEP achieving 45 cmH(2)O and peak pressure of 60 cmH2O, followed by ventilation with optimal PEEP titrated according to the static compliance of the respiratory system. In the control group, mechanical ventilation will follow a conventional protocol (ARDSNet). In both groups, we will use controlled volume mode with low tidal volumes (4 to 6 mL/kg of predicted body weight) and targeting plateau pressure &lt;= 30 cmH2O. The primary outcome is 28-day survival, and the secondary outcomes are: length of ICU stay; length of hospital stay; pneumothorax requiring chest tube during first 7 days; barotrauma during first 7 days; mechanical ventilation-free days from days 1 to 28; ICU, in-hospital, and 6-month survival. ART is an event-guided trial planned to last until 520 events (deaths within 28 days) are observed. These events allow detection of a hazard ratio of 0.75, with 90% power and two-tailed type I error of 5%. All analysis will follow the intention-to-treat principle. Discussion: If the ART strategy with maximum recruitment and PEEP titration improves 28-day survival, this will represent a notable advance to the care of ARDS patients. Conversely, if the ART strategy is similar or inferior to the current evidence-based strategy (ARDSNet), this should also change current practice as many institutions routinely employ recruitment maneuvers and set PEEP levels according to some titration method.Hospital do Coracao (HCor) as part of the Program 'Hospitais de Excelencia a Servico do SUS (PROADI-SUS)'Brazilian Ministry of Healt

    A IMPORTÂNCIA DO INSTITUTO DO DIREITO DE SUPERFÍCIE PARA A FUNCIONALIZAÇÃO DA PROPRIEDADE

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    O Direito de Superfície é um instituto de aplicação ainda embrionária em nosso ordenamento jurídico pátrio, isto porque sua previsão é recente, tendo sido inserido pelo Estatuto da Cidade, conforme Lei 10.257 de 2001, e, posteriormente, pelo Código Civil de 2002. Inicialmente, neste artigo, discorreremos acerca do conceito e objeto do instituto do Direito de Superfície, em seguida, abordaremos acerca da previsão deste instituto em ambos os diplomas legais vigentes, discutindo se há um conflito normativo entre eles, e, por fim, demonstraremos a sua importância para a funcionalização da propriedade

    Does admission acetylsalicylic acid uptake in hospitalized COVID-19 patients have a protective role? Data from the Spanish SEMI-COVID-19 Registry.

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    Acetylsalicylic acid (ASA) is widely used in the treatment and prevention of cardiovascular disorders. Our objective is to evaluate its possible protective role, not only in mortality but also in other aspects such as inflammation, symptomatic thrombosis, and intensive care unit (ICU) admission in hospitalized COVID-19 patients. We realized an observational retrospective cohort study of 20,641 patients with COVID-19 pneumonia collected and followed-up from Mar 1st, 2020 to May 1st, 2021, from the nationwide Spanish SEMI-COVID-19 Registry. Propensity score matching (PSM) was performed to determine whether treatment with ASA affected outcomes in COVID-19 patients. On hospital admission, 3291 (15.9%) patients were receiving ASA. After PSM, 3291 patients exposed to ASA and 2885 not-exposed patients were analyzed. In-hospital mortality was higher in the ASA group (30.4 vs. 16.9%, p
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