Foreign direct investments distribution in the Russian Federation: do spatial effects matter?

In this paper we explore the hypothesis of spatial effects in the distribution of Foreign Direct Investments (FDI) across Russian regions. We make use of a model, which describes FDI inflows as resulting from an agglomeration effect (the level of FDI in a given region depends positively on the level of FDI received by the regions in its neighbourhood) and remoteness effect (the distance of each Russian regions from the most important outflows countries). Considering a panel of 68 Russian regions over the period 2000-2004 we find that the two effects play a significant role in determining FDI inflows towards Russia. The two effects are also robust to the inclusion of other widely used explanatory variables impacting the level of FDI towards countries or regions (e.g. surrounding market potential, infrastructures, investment climate)

X- and gamma-ray studies of HESS J1731-347 coincident with a newly discovered SNR

In the survey of the Galactic plane conducted with H.E.S.S., many VHE gamma-ray sources were discovered for which no clear counterpart at other wavelengths could be identified. HESS J1731-347 initially belonged to this source class. Recently however, the new shell-type supernova remnant (SNR) G353.6-0.7 was discovered in radio data, positionally coinciding with the VHE source. We will present new X-ray observations that cover a fraction of the VHE source, revealing nonthermal emission that most likely can be interpreted as synchrotron emission from high-energy electrons. This, along with a larger H.E.S.S. data set which comprises more than twice the observation time used in the discovery paper, allows us to test whether the VHE source may indeed be attributed to shell-type emission from that new SNR. If true, this would make HESS J1731-347 a new object in the small but growing class of non-thermal shell-type supernova remnants with VHE emission.Comment: 4 pages, 5 figures, to appear in proceedings of the 31st ICRC, Lodz, Polan

The 1998 outburst of the X-ray transient XTE J2012+381 as observed with BeppoSAX

We report on the results of a series of X-ray observations of the transient black hole candidate XTE J2012+381 during the 1998 outburst performed with the BeppoSAX satellite. The observed broad-band energy spectrum can be described with the superposition of an absorbed disk black body, an iron line plus a high energy component, modelled with either a power law or a Comptonisation tail. The source showed pronounced spectral variability between our five observations. While the soft component in the spectrum remained almost unchanged throughout our campaign, we detected a hard spectral tail which extended to 200 keV in the first two observations, but became barely detectable up to 50 keV in the following two. A further re-hardening is observed in the final observation. The transition from a hard to a soft and then back to a hard state occurred around an unabsorbed 0.1-200 keV luminosity of 10^38 erg/s (at 10 kpc). This indicates that state transitions in XTE 2012+281 are probably not driven only by mass accretion rate, but additional physical parameters must play a role in the evolution of the outburst.Comment: Paper accepted for publication on A&A (macro included, 9 pages, 5 figures

Observing Ultra High Energy Cosmic Particles from Space: SEUSO, the Super Extreme Universe Space Observatory Mission

The experimental search for ultra high energy cosmic messengers, from $E\sim 10^{19}$ eV to beyond $E\sim 10^{20}$ eV, at the very end of the known energy spectrum, constitutes an extraordinary opportunity to explore a largely unknown aspect of our universe. Key scientific goals are the identification of the sources of ultra high energy particles, the measurement of their spectra and the study of galactic and local intergalactic magnetic fields. Ultra high energy particles might, also, carry evidence of unknown physics or of exotic particles relics of the early universe. To meet this challenge a significant increase in the integrated exposure is required. This implies a new class of experiments with larger acceptances and good understanding of the systematic uncertainties. Space based observatories can reach the instantaneous aperture and the integrated exposure necessary to systematically explore the ultra high energy universe. In this paper, after briefly summarising the science case of the mission, we describe the scientific goals and requirements of the SEUSO concept. We then introduce the SEUSO observational approach and describe the main instrument and mission features. We conclude discussing the expected performance of the mission

An epistatic mini-circuitry between the transcription factors Snail and HNF4a controls liver stem cell and hepatocyte features exhorting opposite regulation on stemness-inhibiting microRNAs

Preservation of the epithelial state involves the stable repression of EMT program while maintenance of the stem compartment requires the inhibition of differentiation processes. A simple and direct molecular mini-circuitry between master elements of these biological processes, may provide the best device to keep balanced such complex phenomena. In this work, we show that in hepatic stem cell Snail, a transcriptional repressor of the hepatocyte differentiation master gene HNF4, directly represses the expression of the epithelial microRNAs-200c and -34a, which in turn target several stem cell genes. Notably, in differentiated hepatocytes HNF4, previously identified as a transcriptional repressor of Snail, induces the microRNAs-34a and -200a, b, c that, when silenced, causes epithelial dedifferentiation and reacquisition of stem traits. Altogether these data unveiled Snail, HNF4 and microRNAs -200a, b, c and -34a as epistatic elements controlling hepatic stem cell maintenance/differentiation

Disentangling the jet emission from protostellar systems. The ALMA view of VLA1623

Context: High-resolution studies of class 0 protostars represent the key to constraining protostar formation models. VLA16234-2417 represents the prototype of class 0 protostars, and it has been recently identified as a triple non-coeval system. Aim: We aim at deriving the physical properties of the jets in VLA16234-2417 using tracers of shocked gas. Methods: ALMA Cycle 0 Early Science observations of CO(2-1) in the extended configuration are presented in comparison with previous SMA CO(3-2) and Herschel-PACS [OI}] 63 micron observations. Gas morphology and kinematics were analysed to constrain the physical structure and origin of the protostellar outflows. Results: We reveal a collimated jet component associated with the [OI] 63 micron emission at about 8'' (about 960 AU) from source B. This newly detected jet component is inversely oriented with respect to the large-scale outflow driven by source A, and it is aligned with compact and fast jet emission very close to source B (about 0.3'') rather than with the direction perpendicular to the A disk. We also detect a cavity-like structure at low projected velocities, which surrounds the [OI] 63 micron emission and is possibly associated with the outflow driven by source A. Finally, no compact outflow emission is associated with source W. Conclusions: Our high-resolution ALMA observations seem to suggest there is a fast and collimated jet component associated with source B. This scenario would confirm that source B is younger than A, that it is in a very early stage of evolution, and that it drives a faster, more collimated, and more compact jet with respect to the large-scale slower outflow driven by A. However, a different scenario of a precessing jet driven by A cannot be firmly excluded from the present observations.Comment: Accepted for publication in Astronomy & Astrophysic