On the Attenuation of Longitudinal Wave Propagated along a Magneto-Strictive Material

Attenuation calculation in a ferromagnetic material placed in a magnetic field has been worked out in the present paper following operational method. Expression for attenuation/wavelength obtained in the present method is exactly the same as that derived by Leslie (1950). The expression has been successfully used for computing attenuation in a nickel tube at no biasing and the agreement with the result of Wegel & Walther (1935) in the same material is found to be excellent

Cardiovascular disease, chronic kidney disease, and diabetes mortality burden of cardiometabolic risk factors from 1980 to 2010: A comparative risk assessment

Background: High blood pressure, blood glucose, serum cholesterol, and BMI are risk factors for cardiovascular diseases and some of these factors also increase the risk of chronic kidney disease and diabetes. We estimated mortality from cardiovascular diseases, chronic kidney disease, and diabetes that was attributable to these four cardiometabolic risk factors for all countries and regions from 1980 to 2010. Methods: We used data for exposure to risk factors by country, age group, and sex from pooled analyses of population-based health surveys. We obtained relative risks for the effects of risk factors on cause-specific mortality from meta-analyses of large prospective studies. We calculated the population attributable fractions for each risk factor alone, and for the combination of all risk factors, accounting for multicausality and for mediation of the effects of BMI by the other three risks. We calculated attributable deaths by multiplying the cause-specific population attributable fractions by the number of disease-specific deaths. We obtained cause-specific mortality from the Global Burden of Diseases, Injuries, and Risk Factors 2010 Study. We propagated the uncertainties of all the inputs to the final estimates. Findings: In 2010, high blood pressure was the leading risk factor for deaths due to cardiovascular diseases, chronic kidney disease, and diabetes in every region, causing more than 40% of worldwide deaths from these diseases; high BMI and glucose were each responsible for about 15% of deaths, and high cholesterol for more than 10%. After accounting for multicausality, 63% (10·8 million deaths, 95% CI 10·1-11·5) of deaths from these diseases in 2010 were attributable to the combined effect of these four metabolic risk factors, compared with 67% (7·1 million deaths, 6·6-7·6) in 1980. The mortality burden of high BMI and glucose nearly doubled from 1980 to 2010. At the country level, age-standardised death rates from these diseases attributable to the combined effects of these four risk factors surpassed 925 deaths per 100 000 for men in Belarus, Kazakhstan, and Mongolia, but were less than 130 deaths per 100 000 for women and less than 200 for men in some high-income countries including Australia, Canada, France, Japan, the Netherlands, Singapore, South Korea, and Spain. Interpretation: The salient features of the cardiometabolic disease and risk factor epidemic at the beginning of the 21st century are high blood pressure and an increasing effect of obesity and diabetes. The mortality burden of cardiometabolic risk factors has shifted from high-income to low-income and middle-income countries. Lowering cardiometabolic risks through dietary, behavioural, and pharmacological interventions should be a part of the global response to non-communicable diseases. Funding: UK Medical Research Council, US National Institutes of Health. © 2014 Elsevier Ltd

Effects of silver nanoparticles on microbial growth dynamics

Aims: Engineered metal nanoparticles are increasingly used in consumer products, in part as additives that exhibit advantageous antimicrobial properties. Conventional nanoparticle susceptibility testing is based largely on determination of nontemporal growth profiles such as measurements of inhibition zones in common agar diffusion tests, counting of colony-forming units, or endpoint or regular-interval growth determination via optical density measurements. For better evaluation of the dynamic effects from exposure to nanoparticles, a cultivation-based assay was established in a 96-well format and adapted for time-resolved testing of the effects of nanoparticles on micro-organisms. Methods and Results: The modified assay allowed simultaneous cultivation and on-line analysis of microbial growth inhibition. The automated high-throughput assay combined continuous monitoring of microbial growth with the analysis of many replicates and was applied to Cupriavidus necator H16 test organisms to study the antimicrobial effects of spherical silver [Ag(0)] nanoparticles (primary particle size distribution D90\ua

Prospective associations between hsCRP and GlycA inflammatory biomarkers and depression: The Brazilian longitudinal study of adult health (ELSA-Brasil)

Background: Although low-grade inflammation is associated with onset and persistence of depression, most biomarkers display modest predictive effects. GlycA (glycoprotein acetylation) is a unique metabolomic composite of pro-inflammatory acute-phase glycoproteins. We hypothesized that GlycA levels would predict depression incidence, remission and persistence, with higher accuracy than high-sensitivity c-reactive protein (hsCRP). We also explored the additive predictive value of GlycA above and beyond hsCRP. Methods: Cohort design using the sample of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)'s São Paulo site. Baseline GlycA and hsCRP levels were measured in blood plasma. Depression incidence, remission, and persistence were assessed using the Clinical Interview Scheduled Revised (CIS-R) at two time points separated by a mean of 3.8 years. Multivariable Poisson, logistic and linear regression models were used for prediction. Models were adjusted for sociodemographic and clinical confounders, including age, gender, ethnicity, education, cardiovascular assessments, antidepressant and anti-inflammatory drug use, anxiety disorders, alcohol use, and body mass index. Results: We included 4,364 participants (53.2% females, mean age 51.4 ± 8.9 years) with no autoimmune disorders. GlycA robustly predicted depression persistence (relative risk of 7.28, 95% confidence interval 1.33–45.57, p = 0.023 in the fully-adjusted model), but not depression onset. Although hsCRP also predicted depression persistence, its effects were fully explained by confounders and by GlycA levels. GlycA also predicted worsening of depressive symptoms in depressed patients and depression persistence vs. remission in fully-adjusted models. Limitations: Brief depressive episodes could not be measured by our assessments. Conclusions: GlycA might be a new inflammatory prognosis biomarker for depression

O professor, as condições de trabalho e os efeitos sobre sua saúde The teacher, working conditions and their effects on his health

O estudo das relações entre o processo de trabalho docente, as reais condições sob as quais ele se desenvolve e o possível adoecimento físico e mental dos professores constituem um desafio e uma necessidade para se entender o processo saúde-doença do trabalhador docente e se buscar as possíveis associações com o afastamento do trabalho por motivo de saúde. Este artigo apresenta o perfil dos afastamentos do trabalho por motivos de saúde de uma população de profissionais da educação. Buscando elementos na literatura disponível, aventa a hipótese de que as condições de trabalho nas escolas podem gerar sobreesforço dos docentes na realização de suas tarefas. Foram analisados os dados apresentados no Relatório preparado pela Gerência de Saúde do Servidor e Perícia Médica (GSPM) da Prefeitura Municipal de Belo Horizonte, Minas Gerais, relativos aos afastamentos do trabalho de funcionários da Secretaria Municipal de Educação, de abril de 2001 a maio de 2003. Os afastamentos foram indicados pelos atestados médicos fornecidos pela própria instituição. Os dados obtidos, embora não permitissem discriminar o número de professores envolvidos, possibilitaram o conhecimento do número de afastamentos entre os professores, sendo que os transtornos psíquicos ficaram em primeiro lugar entre os diagnósticos que provocaram os afastamentos.<br>The study of the relations between the teaching work process, the real conditions under which it is developed, and the possible physical and mental ailment of teachers constitutes a challenge and a necessity to understand the health-sickness process of teachers, and to seek new associations with sick leaves. This article presents the sick leave profile of a population of professionals in education. Drawing from the available literature, the study raises the hypothesis that the working conditions at schools may be leading to teachers' overload when carrying out their duties. The study analyzed data presented in the Report prepared by the Worker Health Administration and Medical Examination Office (GSPM) of the City of Belo Horizonte, Minas Gerais, corresponding to sick leaves by employees of the Municipal Secretary for Education between April 2001 and May 2003. The sick leaves were recommended in medical reports issued by the GSPM itself. The data obtained, although not allowing to ascertain the total number of teachers involved, made is possible to know the number of sick leaves among teachers. Psychiatric disorders were top of the list among the diagnostics that resulted in sick leaves

Tabagismo passivo no Brasil: resultados da Pesquisa Especial Do Tabagismo, 2008 Passive smoking in Brazil: results from the 2008 Special Survey on Smoking

O objetivo foi descrever prevalência e características sócio-demográficas associadas ao tabagismo passivo no domicílio e no trabalho, em participantes (15+ anos) de amostra populacional da Pesquisa Especial do Tabagismo, sub-amostra da PNAD 2008. O tabagismo passivo é definido como a exposição ao tabaco por não-fumante, em casa, no trabalho ou em outros locais fechados, excluídas ocupações ao ar livre. Associações com características sócio-demográficas foram estimadas por análise de regressão logística. Nos 25.005 não-fumantes, a exposição domiciliar é diária para 12,5% e ocasional para 21%. À regressão multinomial (referência: não-expostos), a exposição diária diminui com aumento de idade e tanto a exposição diária como a ocasional diminuem com maiores escolaridade e renda. Comparada à Região Sudeste, há menor exposição diária no Norte e no Centro-Oeste, e maior ocasional no Nordeste. Dos 10.933 trabalhadores, 55% dos homens e 45% das mulheres relataram exposição no trabalho e 67% exposição domiciliar adicional. A exposição no trabalho é maior em homens, nos mais velhos (55+anos) e com menor escolaridade e renda; e menor no Sul. A desigualdade social no Brasil se revela também na maior exposição ao tabagismo passivo daqueles com menor escolaridade e renda.<br>The scope of this article was to describe indoor passive smoking, at home and at work, among Brazilians (15+ years) participants of the "Special Research on Smoking", a sub-sample of the PNAD 2008. Non-smokers who reported exposure to indoor household smoking were classified as daily or occasional passive smokers, based on the frequency of exposure. Associations with socio-demographic factors were verified by logistic regression analysis. Among 25,005 participants, prevalence of daily and occasional household exposure were 12.5% and 21%, respectively. Compared to those not exposed, daily exposure decreased with increasing age, schooling and income. Occasional exposure is not influenced by age, but decreases with increasing schooling and income. Compared to the Southeast Region, daily exposure was lower in the North and Central West and higher in the Northeast. Among those 10,933 with indoor occupations, 55% of men and 45% of women reported worksite exposure and 67% of them also reported household exposure. Prevalence of exposure at work is higher in men, older adults (55+ years) and among those with lower schooling and income and lower among South Region residents. Social inequality in Brazil is seen in greater exposure to passive smoking among those with lower incomes and less education