Environmental Benefits from Reduced Pesticide Use and Returns to Research: An Application to the U.S. Cotton Industry

Cotton production is one of the main pesticide use industries in the U.S. This intensive use has resulted in the disruption of naturally occurring biological control factors that regulate other insect pest populations and “the pesticide treadmill”. The result is resistance to insecticides, high control costs and unacceptable levels of chemical insecticides in the environment. Concerns about the environmental and human health effects from pesticide use thus need to be modeled in evaluation studies.Cotton, pesticide use, environmental effects, supply function, Crop Production/Industries, Environmental Economics and Policy,

Kinetics of the neutralizing antibody response to respiratory syncytial virus infections in a birth cohort

The kinetics of respiratory syncytial virus (RSV) neutralizing antibodies following birth, primary and secondary infections are poorly defined. The aims of the study were to measure and compare neutralizing antibody responses at different time points in a birth cohort followed-up over three RSV epidemics. Rural Kenyan children, recruited at birth between 2002 and 2003, were monitored for RSV infection over three epidemic seasons. Cord and 3-monthly sera, and acute and convalescent sera following RSV infection, were assayed in 28 children by plaque reduction neutralization test (PRNT). Relative to the neutralizing antibody titers of pre-exposure control sera (1.8 log10 PRNT), antibody titers following primary infection were (i) no different in sera collected between 0 and 0.4 months post-infection (1.9 log10 PRNT, P = 0.146), (ii) higher in sera collected between 0.5 and 0.9 (2.8 log10 PRNT, P < 0.0001), 1.0–1.9 (2.5 log10 PRNT, P < 0.0001), and 2.0–2.9 (2.3 log10 PRNT, P < 0.001) months post-infection, and (iii) no different in sera collected at between 3.0 and 3.9 months post-infection (2.0 log10 PRNT, P = 0.052). The early serum neutralizing response to secondary infection (3.02 log10 PRNT) was significantly greater than the early primary response (1.9 log10 PRNT, P < 0.0001). Variation in population-level virus transmission corresponded with changes in the mean cohort-level neutralizing titers. It is concluded that following primary RSV infection the neutralizing antibody response declines to pre-infection levels rapidly (∼3 months) which may facilitate repeat infection. The kinetics of the aggregate levels of acquired antibody reflect seasonal RSV occurrence, age, and infection history

Fast human activity recognition in lifelogging

This paper addresses the problem of fast Human Activity Recognition (HAR) in visual lifelogging. We identify the importance of visual features related to HAR and we specifically evaluate the HAR discrimination potential of Colour Histograms and Histogram of Oriented Gradients. In our evaluation we show that colour can be a low-cost and effective means of low-cost HAR when performing single-user classification. It is also noted that, while much more efficient, global image descriptors perform as well or better than local descriptors in our HAR experiments. We believe that both of these findings are due to the fact that a user’s lifelog is rich in reoccurring scenes and environments

Negative diffraction pattern dynamics in nonlinear cavities with left-handed materials

We study a ring cavity filled with a slab of a right-handed material and a slab of a left-handed material. Both layers are assumed to be nonlinear Kerr media. First, we derive a model for the propagation of light in a left-handed material. By constructing a mean-field model, we show that the sign of diffraction can be made either positive or negative in this resonator, depending on the thicknesses of the layers. Subsequently, we demonstrate that the dynamical behavior of the modulation instability is strongly affected by the sign of the diffraction coefficient. Finally, we study the dissipative structures in this resonator and reveal the predominance of a two-dimensional up-switching process over the formation of spatially periodic structures, leading to the truncation of the homogeneous hysteresis cycle.Comment: 8 pages, 5 figure

Spectroscopic ellipsometry of composite thin films with embedded Bi nanocrystals

8 pages, 6 figures, 1 table.-- PACS: 78.66.Jg; 78.66.Nk; 78.20.Ci; 68.55.Ln; 07.60.Fs; 81.05.Ys; 68.55.JkSpectroscopic ellipsometry together with an effective medium model is used to determine simultaneously the effective refractive index, thickness, and metal volume fraction of thin nanocomposite films. The films are formed by Bi nanocrystals embedded in amorphous matrices, either semiconducting (Ge) or dielectric (Al2O3). For the Bi:Ge films (metal in an absorbing host), the values obtained for both the real and imaginary parts of the refractive index vary continuously from that of Ge to that of Bi. The metal contents determined from the ellipsometry analysis are in excellent agreement with those obtained from direct measurements of the composition. For the Bi:Al2O3 films (metal in a nonabsorbing host), the extinction coefficient (k) exhibits a maximum around 360 nm which is related to the metal plasmon resonance frequency of Bi nanocrystals. The metal content determined from the ellipsometry analysis in this case is underestimated, probably due to interaction of the Bi crystals with the Al2O3 host.This work has been partially supported by CICYT (Spain) under TIC96-0467 project. The authors are grateful to the GPS (Université de Paris VI et VII, France) for provision and assistance of Rutherford backscattering facilities. One of the authors (J.M.B.) greatly acknowledges a FPI grant from the Spanish Ministry of Education and Culture.Peer reviewe

Variation of Micronutrients in Pumpkin FruitVarieties Grown Within the Lake Victoria Basin

Food shortage is a common occurrence in the developing countries. The shortage is emancipated in both low quantity and poor quality resulting in deficiency based diseases. The fact that pumpkins have an easy production (3-4 month), long shelf life (over six month) and therefore available, should increase their likelihood incorporation in the diet. The study set out to establish the varieties and levels of micronutrients in the fruits of the pumpkins grown by small holder farmers in four districts of Busia, Gucha, Jinja and Tarime within the Lake Victoria Basin. A questionnaire was administered to determine information on the varieties. The levels of ?-carotene, ?-tocopherol and the B-complex vitamins were determined with RP HPLC. Vitamin C was analysed by titration while AAS was used for the analysis of trace elements (zinc, iron and selenium). Standards were run and calibration curve equations with 0.955 ? R2 ? 0.999 used to calculate the concentrations.  Three species of pumpkins Cucurbita maxima, Cucurbitapepo and Cucurbitamoschata were widely distributed. Ten different varieties were sampled. The levels of micronutrients in different varieties (Fruits) showed significant differences that could not be accounted for by chance. At 95 % confidence limit, moisture (p = 0.001), ?-carotene (p = 0.002), thiamine (p = 0.000), riboflavin (p = 0.001), niacin (p = 0.009) and pyridoxine (p = 0.000) varied significantly. Further comparison of the samples from each district equally showed significant differences (p &lt; 0.05) in all micronutrients except vitamin C (p = 0.08) and selenium (p = 0.447) levels. These results indicate non universality in levels of micronutrients in different varieties and between locations enhancing the need for focusing on those superior varieties (like the banana variety) as established in this study. From the levels of the micronutrients (?-carotene 2.220-2.670 mg / 100 g, zinc 0.986-1.728 mg / 100g, iron 2.16-1.68 mg / 100g) established, it is appropriate to popularize the utilization of pumpkins as a conventional rich food source to supplement the traditional cereal based diets aimed at combating the problem of food shortages and malnutrition in the Lake Victoria Basin and developing countries in general

Papel del logopeda en un centro gerontológico de estancias diurnas

[Resumen] El aumento de población anciana en nuestra sociedad es un hecho que ha provocado la aparición de nuevos recursos socio-sanitarios que cubran sus necesidades. El Centro Gerontológico de Estancias Diurnas es un servicio multidisciplinar diurno que se ocupa de la atención social y sanitaria, con actuación terapéutica y preventiva, de los mayores facilitando la vida laboral de las personas que se ocupan ordinariamente de su cuidado. Los centros de día deben proporcionar una atención integral debiendo, por tanto, estar constituidos por un equipo profesional multidisciplinar en el que la figura del logopeda esté presente desarrollando una labor específica. Parece, por tanto, interesante delimitar las funciones básicas a desempeñar, los trastornos más comunes susceptibles de intervención, así como, algunas directrices a tener en cuenta.[Abstract] The increase of the senior population in our society is an event that has provoked the appeareance of a new sort of social and sanitary recource, a structure that has to be concerned with the needs of this population. The gerontologic day-center is in brief a multidisciplinar service, that works during day time, treating the social and sanitary occupation of our elder with both therapeutic and preventive acts. This to provide a normal working life for the people who are usually taking care of these people. Day-centers have to answer these needs with a complete service, and for that reason they have to apile to a multidisciplinar staff in wich the speech-therapist develops a specific role. It seems though interesting to define the basic functions that a professional speech-therapist has to perform, such as the most common disorders capable of treatment and general intervention, as well derectives to bear in mind

Genetic relatedness of infecting and reinfecting respiratory syncytial virus strains identified in a birth cohort from rural Kenya

Background: Respiratory syncytial virus (RSV) reinfects individuals repeatedly. The extent to which this is a consequence of RSV antigenic diversity is unclear. Methods: Six-hundred thirty-five children from rural Kenya were closely monitored for RSV infection from birth through 3 consecutive RSV epidemics. RSV infections were identified by immunofluorescence testing of nasal washing samples collected during acute respiratory illnesses, typed into group A and B, and sequenced in the attachment (G) protein. A positive sample separated from a previous positive by ≥14 days was defined as a reinfection a priori. Results: Phylogenetic analysis was undertaken for 325 (80%) of 409 identified infections, including 53 (64%) of 83 reinfections. Heterologous group reinfections were observed in 28 episodes, and homologous group reinfections were observed in 25 episodes; 10 involved homologous genotypes, 5 showed no amino acid changes, and 3 were separated by 21–24 days and were potentially persistent infections. The temporal distribution of genotypes among reinfections did not differ from that of single infections. Conclusions: The vast majority of infection and reinfection pairs differed by group, genotype, or G amino acid sequence (ie, comprised distinct viruses). The extent to which this is a consequence of immune memory of infection history or prevalent diversity remains unclear

Modulation of Ciliary Phosphoinositide Content Regulates Trafficking and Sonic Hedgehog Signaling Output

SummaryCiliary transport is required for ciliogenesis, signal transduction, and trafficking of receptors to the primary cilium. Mutations in inositol polyphosphate 5-phosphatase E (INPP5E) have been associated with ciliary dysfunction; however, its role in regulating ciliary phosphoinositides is unknown. Here we report that in neural stem cells, phosphatidylinositol 4-phosphate (PI4P) is found in high levels in cilia whereas phosphatidylinositol (4,5)-bisphosphate (PI(4,5)P2) is not detectable. Upon INPP5E inactivation, PI(4,5)P2 accumulates at the ciliary tip whereas PI4P is depleted. This is accompanied by recruitment of the PI(4,5)P2-interacting protein TULP3 to the ciliary membrane, along with Gpr161. This results in an increased production of cAMP and a repression of the Shh transcription gene Gli1. Our results reveal the link between ciliary regulation of phosphoinositides by INPP5E and Shh regulation via ciliary trafficking of TULP3/Gpr161 and also provide mechanistic insight into ciliary alterations found in Joubert and MORM syndromes resulting from INPP5E mutations