Urban containment and neighborhood quality in Florida

Book ChapterRapid suburbanization since World War II in America has created many of the challenges we face today. Roads intended to relieve congestion have become congested. Cookie-cutter subdivisions have replaced scenic landscapes. Once-vital downtown stores have been abandoned as shoppers transferred their allegiance to convenient suburban malls. The spread of low-density residential development made public transit impractical, making the automobile virtually the only choice for transportation. Automobile dependence has degraded the air in some places to alarming levels. Once-tranquil communities with their own unique character have been overwhelmed by more people, automobiles, and shopping centers. But the problem is not growth per se; the problem is how to manage growth in ways that minimize costs and maximize benefits to both individuals and the public at large. Urban containment is an attempt to confront the reasonable development needs of the community, region, or state, and accommodate them in a manner that preserves public goods, minimizes fiscal burdens, minimizes adverse interactions between land uses while maximizing positive ones, improves the equitable distribution of the benefits of growth, and enhances quality of life. At its heart, urban containment aims to achieve these goals by choreographing public infrastructure investment, land use and development regulation, and deployment of incentives and disincentives to influence the rate, timing, intensity, mix, and location of growth. Broadly speaking, urban containment programs can be distinguished from traditional approaches to land use regulation by policies that are explicitly designed to limit the development of land outside a defined urban area, while encouraging infill development and redevelopment inside it

The Initial Stages of Implementing the Western Quail Management Plan

The Western Association of Fish and Wildlife Agencies (WAFWA) established the Western Quail Working Group (WQWG) in July 2009. A memorandum of understanding (MOU) was signed by the western agencies responsible for quail management (Arizona, California, Colorado, Idaho, Kansas, Montana, Nevada, Oklahoma, New Mexico, Oregon, Texas, Utah, and Washington) as ‘‘a cooperative agreement to improve management and implement strategies for conservation of western quail and their habitats.’’ The primary habitat management goals identified by the group are outlined in the Western Quail Management Plan, published by the Wildlife Management Institute in January 2010. Some of the past accomplishments of the WQWG, highlighted at recent WAFWA meetings, include shrub density reductions in New Mexico, riparian habitat restoration in Texas, private landowner habitat improvement cost-share in Kansas, and mesquite removal monitoring in Arizona. Management of western quail and their habitats has traditionally been accomplished on a relatively fine, local scale, so many of the current efforts to implement management practices identified in the plan are undocumented. A need identified by the WQWG is to better engage technical staff to guide outcomes and deliverables outlined in the plan. Additionally, the group is working to update the MOU to include Federal Land Management agencies, to better facilitate land management between state and federal agencies. A technical meeting with state and federal agency staff is scheduled for May 2017 in New Mexico to discuss state progress on implementing the Western Quail Management Plan, and how to increase state interest and efforts towards quail management. The discussions of the technical meeting will be presented at Quail 8

A Machine Learning Classifier Trained on Cancer Transcriptomes Detects NF1 Inactivation Signal in Glioblastoma

We have identified molecules that exhibit synthetic lethality in cells with loss of the neurofibromin 1 (NF1) tumor suppressor gene. However, recognizing tumors that have inactivation of the NF1 tumor suppressor function is challenging because the loss may occur via mechanisms that do not involve mutation of the genomic locus. Degradation of the NF1 protein, independent of NF1 mutation status, phenocopies inactivating mutations to drive tumors in human glioma cell lines. NF1 inactivation may alter the transcriptional landscape of a tumor and allow a machine learning classifier to detect which tumors will benefit from synthetic lethal molecules. We developed a strategy to predict tumors with low NF1 activity and hence tumors that may respond to treatments that target cells lacking NF1. Using RNAseq data from The Cancer Genome Atlas (TCGA), we trained an ensemble of 500 logistic regression classifiers that integrates mutation status with whole transcriptomes to predict NF1 inactivation in glioblastoma (GBM)

Sampling Frame for Mediterranean and Black Sea CFP Monitoring indicators

The Mediterranean and Black Sea list of stocks to be used for computing the indicators was based on a ranking system approach for which the species having a rank in the first ten positions either in total live weight or total economic values were chosen. Landings and economic values for the Mediterranean and Black Sea (FAO area 37) provided by “2016_STECF 16-11 - EU Fleet Economic and Transversal data tables” were used. The reference years were 2012 and 2014 (the last three years available for all the GSAs) and, as geographic strata, the Geographical Sub Areas (GSAs) belonging to EU countries and for which data were available were considered. In the top ranking 10 stocks based on both in terms of live weight and economic value by GSA applied to AER Landings, many combined/nei groups categories were selected. Based on local expert knowledge it was possible split some mixed categories at species level while, it was decided to drop from the list both the misreporting species and the mixed categories for which it wasn't possible defined clearly the species composition. Eventually 230 stocks were selected.JRC.D.2-Water and Marine Resource

Optical, near-IR and sub-mm IFU Observations of the nearby dual AGN Mrk 463

We present optical and near-IR Integral Field Unit (IFU) and ALMA band 6 observations of the nearby dual Active Galactic Nuclei (AGN) Mrk 463. At a distance of 210 Mpc, and a nuclear separation of $\sim$4 kpc, Mrk 463 is an excellent laboratory to study the gas dynamics, star formation processes and supermassive black hole (SMBH) accretion in a late-stage gas-rich major galaxy merger. The IFU observations reveal a complex morphology, including tidal tails, star-forming clumps, and emission line regions. The optical data, which map the full extent of the merger, show evidence for a biconical outflow and material outflowing at $>$600 km s$^{-1}$, both associated with the Mrk 463E nucleus, together with large scale gradients likely related to the ongoing galaxy merger. We further find an emission line region $\sim$11 kpc south of Mrk 463E that is consistent with being photoionized by an AGN. Compared to the current AGN luminosity, the energy budget of the cloud implies a luminosity drop in Mrk 463E by a factor 3-20 over the last 40,000 years. The ALMA observations of $^{12}$CO(2-1) and adjacent 1mm continuum reveal the presence of $\sim$10$^{9}$M$_\odot$ in molecular gas in the system. The molecular gas shows velocity gradients of $\sim$800 km/s and $\sim$400 km/s around the Mrk 463E and 463W nuclei, respectively. We conclude that in this system the infall of $\sim$100s $M_\odot$/yr of molecular gas is in rough balance with the removal of ionized gas by a biconical outflow being fueled by a relatively small, $<$0.01% of accretion onto each SMBH.Comment: Accepted by The Astrophysical Journal, 23 pages, 19 figure

Obscured star formation in intermediate-density environments:A Spitzer study of the Abell 901/902 supercluster

We explore the amount of obscured star formation as a function of environment in the Abell 901/902 (A901/902) supercluster at z = 0.165 in conjunction with a field sample drawn from the A901 and CDFS fields, imaged with the Hubble Space Telescope as part of the Space Telescope A901/902 Galaxy Evolution Survey and Galaxy Evolution from Morphology and Spectral Energy Distributions (SEDs) Survey. We combine the combo-17 near-UV/optical SED with Spitzer 24 mu m photometry to estimate both the unobscured and obscured star formation in galaxies with M-* > 10(10) M-circle dot. We find that the star formation activity in massive galaxies is suppressed in dense environments, in agreement with previous studies. Yet, nearly 40% of the star-forming (SF) galaxies have red optical colors at intermediate and high densities. These red systems are not starbursting; they have star formation rates (SFRs) per unit stellar mass similar to or lower than blue SF galaxies. More than half of the red SF galaxies have low infrared-to-ultraviolet (IR-to-UV) luminosity ratios, relatively high Sersicindices, and they are equally abundant at all densities. They might be gradually quenching their star formation, possibly but not necessarily under the influence of gas-removing environmental processes. The other greater than or similar to 40% of the red SF galaxies have high IR-to-UV luminosity ratios, indicative of high dust obscuration. They have relatively high specific SFRs and are more abundant at intermediate densities. Our results indicate that while there is an overall suppression in the SF galaxy fraction with density, the small amount of star formation surviving the cluster environment is to a large extent obscured, suggesting that environmental interactions trigger a phase of obscured star formation, before complete quenching

Oral tolerance to cancer can be abrogated by T regulatory cell inhibition

Oral administration of tumour cells induces an immune hypo-responsiveness known as oral tolerance. We have previously shown that oral tolerance to a cancer is tumour antigen specific, non-cross-reactive and confers a tumour growth advantage. We investigated the utilisation of regulatory T cell (Treg) depletion on oral tolerance to a cancer and its ability to control tumour growth. Balb/C mice were gavage fed homogenised tumour tissue – JBS fibrosarcoma (to induce oral tolerance to a cancer), or PBS as control. Growth of subcutaneous JBS tumours were measured; splenic tissue excised and flow cytometry used to quantify and compare systemic Tregs and T effector (Teff) cell populations. Prior to and/or following tumour feeding, mice were intraperitoneally administered anti-CD25, to inactivate systemic Tregs, or given isotype antibody as a control. Mice which were orally tolerised prior to subcutaneous tumour induction, displayed significantly higher systemic Treg levels (14% vs 6%) and faster tumour growth rates than controls (p<0.05). Complete regression of tumours were only seen after Treg inactivation and occurred in all groups - this was not inhibited by tumour feeding. The cure rates for Treg inactivation were 60% during tolerisation, 75% during tumour growth and 100% during inactivation for both tolerisation and tumour growth. Depletion of Tregs gave rise to an increased number of Teff cells. Treg depletion post-tolerisation and post-tumour induction led to the complete regression of all tumours on tumour bearing mice. Oral administration of tumour tissue, confers a tumour growth advantage and is accompanied by an increase in systemic Treg levels. The administration of anti-CD25 Ab decreased Treg numbers and caused an increase in Teffs. Most notably Treg cell inhibition overcame established oral tolerance with consequent tumor regression, especially relevant to foregut cancers where oral tolerance is likely to be induced by the shedding of tumour tissue into the gut

Mashing with unmalted sorghum using a novel low temperature enzyme system: impacts of sorghum grain composition and microstructure

Brewing lager beers from unmalted sorghum traditionally requires the use of high temperature mashing and exogenous enzymes to ensure adequate starch conversion. Here, a novel low-temperature mashing system is compared to a more traditional mash in terms of the wort quality produced (laboratory scale) from five unmalted sorghums (2 brewing and 3 non-brewing varieties). The low temperature mash generated worts of comparable quality to those resulting from a traditional energy intensive mash protocol. Furthermore, its performance was less dependent on sorghum raw material quality, such that it may facilitate the use of what were previously considered non-brewing varieties. Whilst brewing sorghums were of lower protein content, protein per se did not correlate with mashing performance. Rather, it was the way in which protein was structured (particularly the strength of protein starch interactions) which most influenced brewing performance. RVA profile was the easiest way of identifying this characteristic as potentially problematic

A new method to quantify and compare the multiple components of fitness-A study case with kelp niche partition by divergent microstage adaptations to Temperature

Point 1 Management of crops, commercialized or protected species, plagues or life-cycle evolution are subjects requiring comparisons among different demographic strategies. The simpler methods fail in relating changes in vital rates with changes in population viability whereas more complex methods lack accuracy by neglecting interactions among vital rates. Point 2 The difference between the fitness (evaluated by the population growth rate.) of two alternative demographies is decomposed into the contributions of the differences between the pair-wised vital rates and their interactions. This is achieved through a full Taylor expansion (i.e. remainder = 0) of the demographic model. The significance of each term is determined by permutation tests under the null hypothesis that all demographies come from the same pool. Point 3 An example is given with periodic demographic matrices of the microscopic haploid phase of two kelp cryptic species observed to partition their niche occupation along the Chilean coast. The method provided clear and synthetic results showing conditional differentiation of reproduction is an important driver for their differences in fitness along the latitudinal temperature gradient. But it also demonstrated that interactions among vital rates cannot be neglected as they compose a significant part of the differences between demographies. Point 4 This method allows researchers to access the effects of multiple effective changes in a life-cycle from only two experiments. Evolutionists can determine with confidence the effective causes for changes in fitness whereas population managers can determine best strategies from simpler experimental designs.CONICYT-FRENCH EMBASSADY Ph.D. gran

Deep weathering in the semi-arid Coastal Cordillera, Chile

The weathering front is the boundary beneath Earth’s surface where pristine rock is converted into weathered rock. It is the base of the “critical zone”, in which the lithosphere, biosphere, and atmosphere interact. Typically, this front is located no more than 20 m deep in granitoid rock in humid climate zones. Its depth and the degree of rock weathering are commonly linked to oxygen transport and fluid flow. By drilling into fractured igneous rock in the semi-arid climate zone of the Coastal Cordillera in Chile we found multiple weathering fronts of which the deepest is 76 m beneath the surface. Rock is weathered to varying degrees, contains core stones, and strongly altered zones featuring intensive iron oxidation and high porosity. Geophysical borehole measurements and chemical weathering indicators reveal more intense weathering where fracturing is extensive, and porosity is higher than in bedrock. Only the top 10 m feature a continuous weathering gradient towards the surface. We suggest that tectonic preconditioning by fracturing provided transport pathways for oxygen to greater depths, inducing porosity by oxidation. Porosity was preserved throughout the weathering process, as secondary minerals were barely formed due to the low fluid flow