Geospatial Clustering and Hot Spot Detection of COVID-19 Incidence in 2020: A Global Analysis

Emergence and spread of Covid-19 initiated diversified researches based on spatial analysis in visualization, exploration, and modelling of this infection. This short communication is an attempt to comprehend the geographic distribution and spatial clustering of Covid-19 in year 2020. Main objective is to spatially analyze Covid-19 incidence rates, identification of hotspots and clusters outliers at global level. Monthly data of reported cases were taken from World Health Organization dashboard and situation reports. Incidence rate was calculated for each country for each month. Spatial autocorrelation techniques of Global Moran are I and Anselian Local Moran’s I were used to examine the spatial clustering and outlier’s detection of Covid-19 incidence in all months of the year. Hotspots and Coldspots variations are examined by using Getis-Ord G*. Mapping was executed in ArcGIS Pro environment. Results reveal significant spatial variation of Covid-19 incidence in WHO regions in different months of pandemic year 2020. Hotspots and high clustering of the disease incidence shows a shift from Western pacific towards Europe and Americas from January to April. Eastern Mediterranean countries also became a part of disease hotspots from the month of July leaving Africa as coldspot during whole year. Highest Moran’s I value of 0.32 with highest z-score of 14 reflects the highly clustered pattern of this pandemic incidence in the month of December in contrary to least clustering of the disease with lowest Moran’s I of 0.02 and z-score of 1.8 in June. Statistically significant variations in disease clustering pattern provides an opportunity for epidemiologists to further explore the disease incidence from ecological perspective

Management of collar rot disease in chili by farmyard manure and commercial biofertilizers

Collar rot of chili (Capsicum annuum L.) is a very destructive disease caused by a soil-borne fungal pathogen Sclerotium rolfsii Sacc. Generally, chemical fungicides are used to combat the menace but this practice is being discouraged because of health and environmental concerns. In the present study, an alternative environment friendly strategy was used to manage this disease by using farmyard manure (FYM) and two commercial biofertilizers namely Biopower and Feng Shou. S. rolfsii inoculated pot soil was amended with 1% and 2% FYM and the two commercial biofertilizers. Inoculation of soil with S. rolfsii only (positive control) resulted in the highest disease incidence (73%) and plant mortality (60%). Biopower and Feng Shou application reduced disease incidence to 20% and 7%, respectively and plant mortality to 0%. Likewise, 1% and 2% FYM amendment reduced disease incidence to 33% and plant mortality to 26% and 7%, respectively. Under biotic stress of S. rolfsii, FYM and biofertilizers applications, either alone or in combination, significantly enhanced root and shoot growth over positive control. S. rolfsii inoculation significantly increased peroxidase and polyphenol oxidase activities in chili plants which were further increased by application of either of the two biofertilizers. The present study concludes that biofertilizers Biopower and Feng Shou alone or in combination with 2% FYM can be effectively utilized to manage southern blight of chili

Exploring the Role of Locational Factors in the Growth of Textile Industry in Tehsil Jaranwala, District Faisalabad

Industrialization is a procedure which contributes to the economy of a country and plays a pivotal role in theexpansion of wealth and economic growth of a community. Textile industry has acted as the backbone of the industrialsector of Pakistan and has contributed a lot in the regional growth especially in Punjab. The present study is aimed toassess the role of locational factors that have proven favorable in the growth and successful development of textileindustry in Jaranwala tehsil, Faisalabad district. An empirical research design was selected and Jaranwala tehsil waschosen as the study area. Both primary and secondary data sources were used, and primary data were collected througha fully-structured questionnaire. Five sample sites were selected, and 75 textile industries were visited, and data wereobtained by interviewing the administrative staff of the respective textile units. The collected data were further arrangedand tabulated by using Microsoft Excel 2010, SPSS 20; Paired sample T test was performed to check the significancebetween types of industries and factors affecting the location of surveyed textile industries. Distributional and thematicmaps were prepared with the help of Arc GIS 10.1. The result of the study showed that availability of raw material,cheap labor and better climatic conditions were the most favorable factors for the location of industries in the studyarea. The study recommends the further work on other types of industries following same pattern in order to understandtheir economic progress in regional growth and development of the study area

Comparison of outcome in medical versus expectant management in unruptured tubal pregnancy with β-hCG 1000-3000 IU/L

Background: Ectopic pregnancy (EP) is an important cause of maternal morbidity as well as mortality in the 1st trimester. This study was done to compare outcome in medical versus expectant management in patients with unruptured tubal pregnancy having β-hCG 1000-3000 IU/L.Methods: In this randomized controlled trial, 82 (41 in each group) women with tubal ectopic pregnancy (TEP) having β-hCG levels between 1000-3000 IU/L and 18 to 40 years of age were enrolled. Women having non-tubal pregnancy, ruptured ectopic pregnancy, heterotopic pregnancy, hypersensitivity to methotrexate were excluded. Included women were randomly assigned to either Group-A (expectant management) or Group-B (medical management). Outcome was measured after one week and considered successful if patient had β-hCG levels negligible i.e. <10 IU/L and complete resolution on ultrasonography (absence of adnexal mass, pelvic free fluid, gestational sac).Results: Overall mean age was 30.65±6.37 years. The mean gestational age in Group-A was 7.12±2.12 weeks and 7.63±2.41 weeks in Group-B. The mean β-hCG levels in Group-A was 1984.63±515.81 IU/L and 1937.33±519.68 IU/L in Group-B. Outcome was successful in 90.24% in Group-A and 63.41% in Group-B (p-value=0.004).Conclusions: Expectant management is associated with better outcome as compared to medical management in tubal ectopic pregnancy having β-hCG between 1000-3000 IU/L

FILE SERIES EFFECTIVELY SEQUENCING CHARACTER-BASED ENCRYPTION IN CLOUD COMPUTING

Within this one finds out about, a comfortable tabulate disposal attribute-based scrape encryption system is usually recommended in cloud-computing. We explain the get dressed sort of relation residence to put an end to the value of motley shipshape shapes discussing. We keep watch over and attain thorough expose for FH-Club penguin-ABE aim. In Existing System take and season for catalogue encryption is sharp and Understanding skill some chance and arithmetic price are greatly significant. The smear tie edifices are built-into only one competitor schmooze, come Sunday whatever, the methodical shapes are encrypted accepting the tied in contiguity club. The get to the bottom of document components roam attributes possibly not unusual by means of the scrapes. Club penguin-ABE procurable schemes which have largely likewise ambidexterity and in this way, are other possess oneself of for vast applications. Multiple grouped tabulates discussing are fixed accepting get dressed style of entrance federation. In hidden edifice the two unravel idea store room and age award of tabulate encryption are released. Within the control of your shapes burgeoning, the advantages of us arrange form progressively higher ear-splitting. Therefore, the two zero reader store and future loan of tabulate encryption are owned. Further likewise, the well-considered design is demonstrated to change into trusty scale down the blueprint assumption

In vitro Anti-ulcer potential of Raphanus sativus L. seeds

Background: Raphanus sativus L. is an indigenous plant that is traditionally used to treat peptic ulcer. Objective: This study assessed anti- Helicobacter pylori, antioxidant, and anti-urease activities of R. sativus seeds. Methods: this study targeted in-vitro model. The antioxidant activity of the methanol extract and n-butanol, aqueous, n- hexane and chloroform fractions of R. sativus seeds was determined using DPPH. Moreover, the inhibitory effects of the extract and fractions on the activity of urease and antibacterial activity against Helicobacter pylori were also evaluated. Results: The crude extract as well as its derived n-butanol fraction exhibited higher (IC50: 45 and 31 µg/mL respectively) DPPH inhibition activity and inhibition of urease (IC50: 75.0 and 55.9 µg/mL respectively) while aqueous extract inhibited H. pylori strongly (MIC50: 15 µg/mL).&nbsp;Conclusion: Collectively, our data show that R. sativus extract and fractions possess antioxidant, anti- H. pylori and anti-urease potential. The traditional uses of R. sativus as anti-ulcer, might be due to its anti-urease activity

Parkinson disease: identifying different players sharing a common principle

Parkinson disease is a multifactorial molecular disorder. Miscellaneous regulators have been characterized to date and their implication in disease progression is well documented. Compromised neuromuscular activity is a serious threat posed by malfunctioning of various regulators. The integrity and maintenance of neural architecture underpins neural activities. Despite the fact that various breakthroughs have been made, yet many proteins are unidentified while some unaddressed. Furthermore, miRNA pathway impairment results in subversion of core biological system and draws attention towards novel miRNA-based therapeutic strategies. Thus proteins and mitrons work in collaboration with various cellular organelles to ensure normal dynamics of neural circuitry. In this review we will emphasize the derailed activities of proteins at molecular level that might help in getting a step closer to personalized medicine

ANTIFUNGAL POTENTIAL OF LEAF EXTRACTS OF LEGUMINOUS TREES AGAINST SCLEROTIUM ROLFSII

Background: Sclerotium rolfsii Sacc. is a destructive soil-borne plant pathogen that infects over 500 plant species and causes significant yield losses in many economically important plant species. Synthetic fungicides used to combat the menace also pollute the environment and cause health hazards. In order to search environmental friendly alternatives from natural resources, in the present study, methanolic extracts of three leguminous tree species namely Acacia nilotica (L.) Willd. ex Delile subsp. indica (Benth.) Brenan, Prosopis juliflora (Sw.) DC. and Albizia lebbeck (L.) Benth. were evaluated for their antifungal activity against S. rolfsii. Materials and Methods: Two hundred grams dried leaf material of each of the three test plant species were extracted with methanol for two weeks. After filtration, methanol was evaporated on a rotary evaporator. Malt extract broth was used to make various concentrations of the crude methanolic extracts and their antifungal potential was determined by comparing the fungal biomass in various treatments with control. Chemical composition of methanolic leaf extract of A. nilotica subsp. indica was determined through GC-MS analysis. Results: Methanolic leaf extract of A. nilotica subsp. indica showed the highest fungicidal activity. Fungal biomass was decreased by 17-55% due to various concentrations of this extract over control. Different concentrations of P. juliflora reduced fungal biomass by 3-52%. Fourteen compounds were identified in methanolic extract of A. nilotica subsp. indica. 9,12,15-octadecatrienoic acid, methyl ester, (Z,Z,Z,)- (16.59%) was the most abundant compound followed by 1-pentanol, 2 methyl-, acetate (14.80%); hexanedioic acid, dimethyl ester (13.10%) and cyclotriaconta- 1, 7, 16, 22-tetraone (10.28%). Conclusion: This study concludes that methanolic leaf extract of A. nilotica subsp. indica can be used for management of S. rolfsii

Forensic Analysis of Tor Browser on Windows 10 and Android 10 Operating Systems

Smartphones and Internet have become prevalent in our society with various applications in businesses, education, healthcare, gaming, and research. One of the major issues with the Internet today is its lack of security since an eavesdropper can potentially intercept the communication. This has contributed towards an increased number of cyber-crime incidents, resulting in an increase in users’ consciousness about the security and privacy of their communication . One example is the shift towards using private browsers such as Tor. Tor is a well-recognized and widely used privacy browser based on The Onion Router network that provisions anonymity over the insecure Internet. This functionality of Tor has been a major hurdle in cybercrime investigations due to the complex nature of its anonymity. This paper investigates artifacts from the Tor privacy browser on the latest Windows 10 and Android 10 devices to determine potential areas where evidence can be found. We examine the registry, storage, and memory of Windows 10 devices and the memory, storage, logs, and Zram of Android 10 devices for three possible scenarios i.e. before, during, and after use of the Tor browser. Our results do not support the claims made by the Tor Project regarding user privacy and anonymity. We find that it is possible to retrieve significant details about a user’s browsing activities while the Tor browser is in use as well as after it is closed (on both operating systems). This paper also provides an investigative methodology for the acquisition and analysis of Tor browser artifacts from different areas of the targeted operating systems. Therefore, it can serve as a base to expand research in the forensic analysis of other privacy browsers and improve the efficiency of cybercrime investigations efficiency

Implementation and evaluation of a social media-based communication strategy to enhance employee engagement: Experiences from a children\u27s hospital, Pakistan

Social media can complement organizational communication strategy which is integral to employee engagement. However, successful case studies which can allow replication are limited. The objective of the study is to describe the design, implementation, and evaluation of a social media-based communication strategy in a tertiary care hospital in Pakistan. The leadership of the pediatric service line developed an intervention plan to engage the employees with the newly reframed vision to improve patient and family experience. An online communication platform-Facebook page-was created for all employees of the pediatric service line. The strategy to influence employees was based on Cialdini\u27s six principles of persuasion. Implementation of the strategy between October 2017 and December 2019 was evaluated for reach, discussion themes, and outcomes using the framework by Murdough (2009). Quantitative indicators included total posts, mean comments, and reactions per post. Posts were qualitatively analyzed with an emergent approach for insights into the discussion. The analysis revealed a total of 9,085 posts, with mean reactions per post of 8.4, mean comments of 7.2, and active viewership by 90% members on average. In terms of post types, photos were the highest (4,779), while videos were the lowest (1,163). Qualitative analysis indicated 54% of the posts were of the theme inspirational and thought provoking, while the greatest engagement was generated on the theme challenges and solution. The authors conclude that the strategy was successfully implemented to maintain active membership, engage employees in meaningful conversations, and have them express intent to execute quality improvement projects