Are "Smart Cities” also “Climate Smart”? An Assessment of the EU Mission “Climate-Neutral and Smart Cities”

ABSTRACT: Urbanization and the concentration of energy-consuming economic activities make cities responsible for more than 70% of global greenhouse gas emissions. At the same time, cities are becoming increasingly vulnerable to climate change impacts. The EU Mission “Climate-Neutral and Smart Cities”, recently launched a call for starting a pathway towards “100 climate-neutral and smart cities by 2030”. The list of 336 candidate cities (86% from the EU-27 and 14% from associated or negotiating countries) was published in February 2022. The cities constitute a very large and diverse sample that was used to conduct this timely research to identify the main factors that can drive and support a smart and sustainable transition of urban areas. A critical analysis of the main achievements in five main driving factors (local climate planning, climate emergency declaration, participation in networks, international projects and competitions) provides insights on the main factors driving cities towards climate smart actions. Results show that 76% of the cities have a local climate, in 82% of cases developed under the Global Covenant of Mayors for Climate and Energy, which involves about 75% of the candidate cities. URBACT is the most popular funding programme, with 23% of cities involved in at least one funded project. The five selected driving factors seem to capture fairly well the level of "activism" of the sample cities in pursuing smart and climate-related projects and initiatives (15 of the 16 cities that have initiatives and activities in their background that fall into all five sets of the Venn diagram are among the 112 cities selected in this first phase of Mission 100 CNSC). 90% of the sample cities are part of at least one Transnational Municipal Network, which is the most important influencing factor, among the five analysed, for cities applying for this Mission. The original results of this timely study can be useful to decision-makers at all levels, but especially to other cities, to enhance knowledge on steps to be taken to accelerate the transition to carbon neutrality. Moreover, the rich dataset made available by this research represents an important knowledge base not only for future monitoring of the selected cities' progress during the implementation phases, but also for the desired replication effects in other urban areas.N/

Key dimensions of cities' engagement in the transition to climate neutrality

ABSTRACT: Urbanization and the concentration of energy-consuming economic activities make cities responsible for more than 70% of global greenhouse gas emissions. At the same time, cities are becoming increasingly vulnerable to climate change impacts. The European Cities Mission launched a call in September 2021 to set out on a path towards "100 climate-neutral and smart cities by 2030". A very large and diverse sample of 344 candidate cities in 35 countries (a subset of the 362 considered eligible to participate in the Cities Mission) was used to conduct this timely research aimed at identifying the main dimensions on which cities are working to achieve a smart and sustainable transition.The research focused on five main dimensions: local climate planning, climate emergency declarations, participation in networks, international projects and competitions. Results show that only 20 (5.8%) cities have no experience in any of them, while there are 18 (5.2%) cities that have in their background activities that fall under all dimensions. Moreover, networking is the most important dimension, among the five analysed, for cities applying for this Mission, involving 309 cities (approximately 90% of the sample). This is followed by local climate planning, involving 275 cities (80%) and city participation in international projects, involving 152 cities (44%). Cities that have declared a climate emergency are less than a fifth of the sample and are very unevenly distributed in only 37.1% of the countries represented (interestingly, all the UK cities in the sample). Similarly, only 49 cities (14.2%) have received international awards.The results provide insights into the main efforts currently being made by cities to engage in the transition to climate neutrality and may be useful to practitioners, scholars and policy-makers at all levels to improve their knowledge of the steps they need to take to support this process and amplify its scope.info:eu-repo/semantics/publishedVersio

Males with low serum levels of vitamin D have lower pregnancy rates when ovulation induction and timed intercourse are used as a treatment for infertile couples: results from a pilot study

Background: Vitamin D (Vit D) is important for the regulation of reproductive physiology. In humans, maternal Vit D deficiency has been implicated in several reproductive- and pregnancy-related disorders. Very few data are available regarding the Vit D status in male partners of couples attempting pregnancy. This observational study (IRB Prot. N. 078/13) aimed to evaluate whether low Vit D serum levels in males might decrease the rate of successful conception in couples attempting pregnancy. Methods: Male and female partners of infertile couples (n = 102) were classified into 2 GROUPS according to normal (≥30 ng/ml) or low (below 30 ng/ml) serum Vit D levels in male partners. Semen analysis was performed in each male participant based on the WHO reference criteria. The female partners of both groups were subjected to 3 consecutive cycles of gonadotropin-induced mono-ovulation. The main outcome measures included the clinical pregnancy rate, delivery per patient and per cycle, and miscarriage rate between the 2 groups evaluated at the end of the three-month period of the study. Results: In male partners of both groups, standard semen analysis did not highlight substantial differences in sperm concentration, sperm progressive motility, or typical form. The pregnancy rates per patient and per cycle and delivery rates per patient and per cycle were all significantly higher (p< 0.05) in couples with normal Vit D levels. Conclusions: These results suggest the existence of a relationship between male Vit D serum levels and semen ability to begin a pregnancy during cycles of timed vaginal intercourse. © 2015 Tartagni et al

A methodological integrated approach to analyse climate change effects in agri-food sector: The TIMES water-energy-food module

The European Union’s 2030 climate and energy policy and the 2030 Agenda for Sustainable Development underline the commitment to mitigate climate change and reduce its impacts by supporting sustainable use of resources. This commitment has become stricter in light of the ambitious climate neutrality target set by the European Green Deal for 2050. Water, Energy and Food are the key variables of the “Nexus Thinking” which face the sustainability challenge with a multi-sectoral approach. The aim of the paper is to show the methodological path toward the implementation of an integrated modeling platform based on the Nexus approach and consolidated energy system analysis methods to represent the agri-food system in a circular economy perspective (from the use of water, energy, biomass, and land to food production). The final aim is to support decision-making connected to climate change mitigation. The IEA-The Integrated MARKAL-EFOM System (TIMES) model generator was used to build up the Basilicata Water, Energy and Food model (TIMES-WEF model), which allows users a comprehensive evaluation of the impacts of climate change on the Basilicata agri-food system in terms of land use, yields and water availability and a critical comparison of these indicators in different scenarios. The paper focuses on the construction of the model’s Reference Energy and Material System of the TIMES model, which integrates water and agricultural commodities into the energy framework, and on the results obtained through the calibration of the model β version to statistical data on agricultural activities.publishersversionpublishe

Regret affects the choice between neoadjuvant therapy and upfront surgery for potentially resectable pancreatic cancer

Background: When treating potentially resectable pancreatic adenocarcinoma, therapeutic decisions are left to the sensibility of treating clinicians who, faced with a decision that post hoc can be proven wrong, may feel a sense of regret that they want to avoid. A regret-based decision model was applied to evaluate attitudes to-ward neoadjuvant therapy versus upfront surgery for potentially resectable pancreatic adenocarcinoma.Methods: Three clinical scenarios describing high-, intermediate-, and low-risk disease-specific mortality after upfront surgery were presented to 60 respondents (20 oncologists, 20 gastroenterologists, and 20 surgeons). Respondents were asked to report their regret of omission and commission regarding neo-adjuvant chemotherapy on a scale between 0 (no regret) and 100 (maximum regret). The threshold model and a multilevel mixed regression were applied to analyze respondents' attitudes toward neo-adjuvant therapy.Results: The lowest regret of omission was elicited in the low-risk scenario, and the highest regret in the high-risk scenario (P < .001). The regret of the commission was diametrically opposite to the regret of omission (P < .001). The disease-specific threshold mortality at which upfront surgery is favored over the neoadjuvant therapy progressively decreased from the low-risk to the high-risk scenarios (P <=.001). The nonsurgeons working in or with lower surgical volume centers (P = .010) and surgeons (P = .018) accepted higher disease-specific mortality after upfront surgery, which resulted in the lower likelihood of adopting neoadjuvant therapy.Conclusion: Regret drives decision making in the management of pancreatic adenocarcinoma. Being a surgeon or a specialist working in surgical centers with lower patient volumes reduces the likelihood of recommending neoadjuvant therapy.(c) 2023 Elsevier Inc. All rights reserved

How are Italian and Spanish cities tackling climate change? A local comparative study

27 p.Cities are widely recognised as being pivotal to fight climate change. They magnify the drivers of climate change, experience the impacts and also concentrate the highest room for action. Although urban areas are broadly claimed to be climate leaders, there is no archetype of right actions given the highly contextual differences among them. Yet, the how and why cities respond to global environmental challenges in the context of increasingly competitive economies needs further research. In this paper we aim at advancing in this regard by assessing the state of the art on urban climate actions in two European Mediterranean Countries: Spain and Italy that face similar climate change challenges. Based on an extensive review of documents, we analyse mitigation and adaptation plans of 26 Spanish and 32 Italian Urban Audit cities, as representative samples. Our results show relevant differences between Spanish and Italian cities in terms of the starting time of their climate actions as well their implementation. We concur with existing literature in that mitigation is more advanced than adaptation actions and take evidence in both countries and we also demonstrate that international and national networking initiatives are being instrumental in engaging cities in climate action

Implications of governance structures on urban climate action: evidence from Italy and Spain

47 p.Cities are widely recognised as being pivotal to fight climate change. Cities magnify the drivers of climate change, experience the impacts and also concentrate the highest room for action. Given the 70% of the global emissions that cities are responsible for, national governments are unable to meet their international commitments for addressing mitigation and adaptation without the action and cooperation of cities. In turn, the capacity of local governments to address climate change is largely determined by the institutional architecture within which they are integrated. As a result, the relationship between the different arenas of authority and the integration of cities in national and international networks is considered critical in shaping the global capacity to govern climate change. This work aims to understand how multi-level climate governance and alliances of cities (national and international) are influencing the climate change capacity and performance of municipalities. This has been done by focusing on two national contexts of the European Union, Italy and Spain, in which climate policy, multi-level governance frameworks, the effects of the national and international networks of cities, and the climate response of cities are analysed through an extensive review of scientific and grey literature, and institutional documents. The results concur with existing literature on the importance of constructing collaborative multi-level climate frameworks at the national scale, that fully integrate the local level, in order to support cities to develop consistent climate action and raise awareness of the responsibility they have in this policy field

The hepatitis B x antigen anti-apoptotic effector URG7 is localized to the endoplasmic reticulum membrane

Hepatitis B x antigen up-regulates the liver expression of URG7 that contributes to sustain chronic virus infection and to increase the risk for hepatocellular carcinoma by its anti-apoptotic activity. We have investigated the subcellular localization of URG7 expressed in HepG2 cells and determined its membrane topology by glycosylation mapping in vitro. The results demonstrate that URG7 is N-glycosylated and located to the endoplasmic reticulum membrane with an Nlumen–Ccytosol orientation. The results imply that the anti-apoptotic effect of URG7 could arise from the C-terminal cytosolic tail binding a pro-apoptotic signaling factor and retaining it to the endoplasmic reticulum membrane

Types of Corruption in Small and Micro Enterprises (SMEs) in Ibadan, Nigeria

Corruption is a phenomenon that manifests in various types and forms especially among operators of Small and Micro Enterprises (SMEs). Many actions of the operators which constitute corrupt practices often tend to be overlooked in spite of their grave consequences for the success SMEs in Nigeria. The fight against corruption in Nigeria is more concentrated in the formal sector. This study was, therefore, designed to investigate various forms in which corrupt practices are carried out among Small and Micro Enterprises in Ibadan, Nigeria. Business owners, their employees, apprentices and consumers constituted the study population. Primary data were collected using questionnaire administered on 200 business owners, 150 employees and 150 apprentices randomly chosen in five business districts in Ibadan; and the conduct of 10 in-depth interviews with purposively selected participants. Quantitative data were analysed at uni-variate level using simple percentages and frequencies while qualitative data were content analysed. Findings from the study revealed that corrupt practices were rampant among actors in SMEs and the common types of corrupt practices included stealing (60%), deception of customers (78.4%), tax evasion (62%), sale of fake products (76%), sale of expired products (65.2%), tampering with measurement scales (69.6%), bribery (82.4%), and poor service delivery (73%). The study concludes that the level of corruption in SMEs calls for concern and government should extend the fight against corruption to the informal sector in Nigeria