El uso de la plataforma Moodle en Historia del Pensamiento Jurídico y Político : Una experiencia en la carrera de Abogacía de la Universidad Nacional de San Luis

El presente trabajo se enmarca en el proyecto de investigación denominado “Las Nuevas Tecnologías de la Información y la Comunicación en Educación Superior” de la Facultad de Ingeniería y Ciencias Económico-Sociales de la Universidad Nacional de San Luis. Se analiza la implementación de la Plataforma Educativa Moodle en la asignatura Historia del Pensamiento Jurídico y Político, que se dicta en el primer año de las Carreras de Ciencias Jurídicas en esta facultad. Para ello, se detallan las herramientas usadas, las actividades que se desarrollaron en la plataforma y los resultados de esta innovación. También se presentan las opiniones de alumnos y docentes de dicha asignatura en cuanto al uso de dicha plataforma y planes de mejoras para futuros dictados. El objetivo de esta presentación es investigar si la utilización de la plataforma educativa en esa asignatura facilitó el trabajo docente y de los alumnos, es decir, el proceso de enseñanza aprendizaje y si se optimizó el uso del Sistema de Gestión de Cursos Moodle.Eje: Innovación y desarrollos tecnológicos en educación a distanciaDirección de Educación a Distancia, Innovación en el aula y TI

Post-pandemic innovation: a six-session visual telerehabilitation program for children

[EN] The Covid-19 pandemic has led orthoptics to the practice of telematic rehabilitation with visually impaired children (VI). Previous research, on protocols developed during the peak of pandemic emergency, highlighted the importance of keeping similar characteristics of the traditional rehabilitation setting in the telematic one. While the world is moving forward from the pandemic, a new awareness about the importance of ICTs in healthcare has spread. Thus, visual telerehabilitation should be improved into a stand-alone method. This paper presents a six-session visual telerehabilitation program with age-specific exercises, developed via Microsoft PowerPoint, training visual attention, visual-spatial motor coordination, visual pursuit, saccadic eye movement, visual search, eye-hand coordination. The sessions are provided via Microsoft Teams where the orthoptist and the child are engaged in a video call (via tablets and personal computers) with the screen-sharing option. Moreover, two tools to monitor the effectiveness of this protocol are presented and discussed: (i) ergo-perimetric evaluation; (ii) ecological evaluation provided by parents.Perasso, G.; Baghino, C.; Cocchi, E.; Dini, S.; Panizzi, A.; Salvagno, V.; Santarello, M. (2023). Post-pandemic innovation: a six-session visual telerehabilitation program for children. Editorial Universitat Politècnica de València. 45-52. https://doi.org/10.4995/INN2022.2022.15715455

Visual telerehabilitation in the Covid-19 era: tradition meets innovation

[EN] Visual telerehabilitation is crucial to rise to the challenges of Covid-19 in order to advocate impaired individuals’ adaptation and social inclusion. The present research aims at detecting the predictors of the visual telerehabilitation protocol’s best outcome, also exploring variables’ interactions. The protocol by Chiossone Institute (Italy, Genoa) was administered in 2020 (March-May). Patients weekly video-called the orthoptists (by tablet or PC) to follow a personalized program on residual vision and diagnosis. The sample included seventy-five visually impaired individuals, across different age ranges (n=46 children and n=29 adults), who had all begun in person rehabilitation before pandemic. To detect the predictors of visual telerehabilitation effectiveness, orthoptists completed a self-report sheet with evaluation of the reaction time, participants socio-demographical data, diagnosis, residual vision, telematic session time-length, compliance level.  Descriptive, linear regression, and moderation analyses were implemented. Children’s reaction time was predicted by age, sessions’ time-length, and compliance. Adults’ reaction time was predicted by sessions’ time length, without significant moderators. These findings encourage the combination of traditional setting elements and technological innovation.Perasso, G.; Baghino, C.; Capris, E.; Cocchi, E.; Dini, S.; Facchini, V.; Panizzi, A.... (2022). Visual telerehabilitation in the Covid-19 era: tradition meets innovation. En Proceedings INNODOCT/21. International Conference on Innovation, Documentation and Education. Editorial Universitat Politècnica de València. 41-48. https://doi.org/10.4995/INN2021.2021.13321OCS414

Aging: a portrait from gene expression profile in blood cells

The availability of reliable biomarkers of aging is important not only to monitor the effect of interventions and predict the timing of pathologies associated with aging but also to understand the mechanisms and devise appropriate countermeasures. Blood cells provide an easily available tissue and gene expression profiles from whole blood samples appear to mirror disease states and some aspects of the aging process itself. We report here a microarray analysis of whole blood samples from two cohorts of healthy adult and elderly subjects, aged 43 +/- 3 and 68 +/- 4 years, respectively, to monitor gene expression changes in the initial phase of the senescence process. A number of significant changes were found in the elderly compared to the adult group, including decreased levels of transcripts coding for components of the mitochondrial respiratory chain, which correlate with a parallel decline in the maximum rate of oxygen consumption (VO2max), as monitored in the same subjects. In addition, blood cells show age-related changes in the expression of several markers of immunosenescence, inflammation and oxidative stress. These findings support the notion that the immune system has a major role in tissue homeostasis and repair, which appears to be impaired since early stages of the aging process

Effects of eight weeks of aerobic interval training and of isoinertial resistance training on risk factors of cardiometabolic diseases and exercise capacity in healthy elderly subjects

We investigated the effect of 8 weeks of high intensity interval training (HIT) and isoinertial resistance training (IRT) on cardiovascular fitness, muscle mass-strength and risk factors of metabolic syndrome in 12 healthy older adults (68 yy \ub1 4). HIT consisted in 7 two-minute repetitions at 80%-90% of V\ucb\u99O2max, 3 times/w. After 4 months of recovery, subjects were treated with IRT, which included 4 sets of 7 maximal, bilateral knee extensions/flexions 3 times/w on a leg-press flywheel ergometer. HIT elicited significant: i) modifications of selected anthropometrical features; ii) improvements of cardiovascular fitness and; iii) decrease of systolic pressure. HIT and IRT induced hypertrophy of the quadriceps muscle, which, however, was paralleled by significant increases in strength only after IRT. Neither HIT nor IRT induced relevant changes in blood lipid profile, with the exception of a decrease of LDL and CHO after IRT. Physiological parameters related with aerobic fitness and selected body composition values predicting cardiovascular risk remained stable during detraining and, after IRT, they were complemented by substantial increase of muscle strength, leading to further improvements of quality of life of the subjects

Comunicazione e Linguaggi non verbali Variazioni sul corpo. Pratiche educative, rieducative e terapeutiche

il volume presenta tre percorsi educativi e rieducativi , attraverso il corpo

Evaluation of metalloproteinases 2 and 9 and their inhibitors in physiologic and preeclamptic pregnancy.

Matrix metalloproteinases (MMPs) are a family of zinc and calcium-dependent endopeptidases involved in remodeling and physiological homeostasis of extracellular matrix (ECM). The metalloproteinases activity is predominantly modulated by specific tissue inhibitors of matrix metalloproteinases (TIMPs). The balance between MMPs and TIMPs is likely to play an important role in remodeling uterine arteries in pregnancy, and it may represent means by which vasodilatation is maintained in later pregnancy. Moreover, increased levels of MMPs and in particular MMP-2 play a role in the vascular alterations induced by hypertension. The aim of this study was the evaluation of MMP-2 and -9, along with their inhibitors TIMP-1 and -2, in pre-eclamptic women compared with normotensive pregnancy and non-pregnant women. Fourteen pre-eclamptic women were compared with 37 normotensive women in different gestational age and 21 non-pregnant women. Multiplexed sandwich enzyme-linked immunosorbent assay was used to measure MMPs and TIMPs simultaneously. MMP-2 levels were significantly higher in preeclamptic women vs. both non-pregnant and physiologic pregnant women. MMP-9 concentrations were significantly higher in physiologic pregnant vs. non-pregnant women. The serum levels of TIMP-1 were significantly higher in pre-eclamptic vs. both non-pregnant and physiologic pregnant women. TIMP-2 values were higher in physiologic pregnant women and pre-eclamptic women vs. non-pregnant women. A positive correlation between MMP-9 values and gestational age was observed in normal pregnant women. Results of the present investigation confirm that MMP-2 and TIMP-1 values are significantly higher in preeclampsia. We confirm that the modification of the fine balance between MMPs and their inhibitors plays a greater role in the structural and functional vascular changes of women with complicated pregnancie

Procalcitonin values in preeclamptic women are related to severity of disease.

Procalcitonin values in preeclamptic women are related to severity of diseas

The utility of serum human epididymis protein 4 (HE4) in patients with a pelvic mass.

AIM: Although CA125 is the most widely used cancer marker in the diagnostic approach of pelvic masses in women, its clinical usefulness is limited because it lacks expression of the antigen in the early stages of disease. The human epididymis protein 4 (HE4) is frequently over-expressed in ovarian cancer, whereas its expression in normal tissues, including the ovary, is low. The aim of this study was to assess the concentration of both HE4 and CA125 in patients with different forms of benign and malign pelvic masses.METHODS: The study population included 99 patients with gynecological cancer (46 ovarian, 39 endometrial, 14 cervical) and 40 affected by benign disease (22 endometriosis and 18 benign ovarian mass). Twelve control subjects were also included in the study. In all the patients, serum samples were collected on the day before scheduled surgery.RESULTS: The median CA125 and HE4 serum levels were significantly higher among ovarian cancer patients as compared with healthy subjects and with those with benign mass, cervical, and endometrial tumors. The receiver operating characteristics curve analysis on healthy controls and patients with ovarian cancers revealed that HE4 had a significantly higher area under the curve when compared with CA125 (0.99 vs. 0.91), with a sensibility and specificity of 98 and 100%, respectively.CONCLUSIONS: HE4 seems to be a promising ovarian cancer marker, and its measurement might improve the diagnostic approach to patients with pelvic masses

Ischemia modified albumin in gynecologic malignancies

Ischemia modified albumin (IMA), as measured using the albumin cobalt binding test, is currently the most promising biomarker for early detection of ischemia before the onset of irreversible cardiac injury. The aim of the study was to evaluate a possible association between IMA values and gynecologic malignancy