178 research outputs found

    From Habits to Habitus: Chinese Elites Attempt to Create an Aristocratic Class Along the British Model

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    Lately, new trends have appeared in the spending habits of Chinese elites, which include money spent on etiquette classes, butler service, British afternoon tea, debutante balls, education in boarding schools, and immigration to Britain. These new consumption patterns of Chinese elites signify their desire and attempt to adopt the British aristocratic lifestyle portrayed in popular TV series, classical novels and mass media. This study examines anthropological research, documentary videos, news reports and interviews with Chinese elites and applies Bourdieu’s theory of habitus as the main analytical tool in order to explain this phenomenon. Considering that forty years ago all Chinese people were at a similar class status—meaning that everybody came from the same or at least a very similar habitus—this research argues that the richest people in China are trying to create a new habitus: the aristocratic class. Furthermore, immigration to Britain, as a variation of lifestyle migration, and education in British boarding schools, can be regarded as pathways to this new habitus. This study attempts to answer whether it is possible to convert financial capital into social and cultural capital, and what implications these issues have on local and global scales. This research builds a foundation for further discussion about creating a new habitus in a very globalized and interactive world, which provides abundant opportunities to experiment with self-identity

    ECONOMIC PROSPECTS FOR INVOLVEMENT OF INVESTORS TO RESOLVE ECONOMIC PROBLEMS OF BIG SEAPORTS AT THE WESTERN BLACK SEA OF UKRAINE

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    На основі проведеного SWOT аналізу досліджено економічні перспективи участі інвесторів у розв’язанні економічних проблем великих морських портів у західній частині Чорного моря України.; The research of investors’ involvement economic prospects to resolve economic problems of big seaport at the western Black Sea of Ukraine has been performed applying SWOT analysis

    Preparation and properties of hibryd organic-inorganic composites baced on poly-Ti02

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    Optically transparent hybrid organic-inorganic copolymers based on the poly- TiO2, vinyl monomers and lactide or glycolide have been prepared. Optical and physi- cal-mechanical properties of composites are depended with the ratio of components have shown. Hybrid copolymers possess photochromic properties. By the UV light excitation reversible darkening of the samples due to the transition Ti 4+ ļ Ti 3+ had observed. The speed of transition depends on the copolymer composition. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/2059

    On the Problem of Prior-Labor Relations

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    The article deals with the factors influencing labor productivity at enterprise

    Novel Semisynthetic Derivatives of Bile Acids as Effective Tyrosyl-DNA Phosphodiesterase 1 Inhibitors.

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    An Important task in the treatment of oncological and neurodegenerative diseases is the search for new inhibitors of DNA repair system enzymes. Tyrosyl-DNA phosphodiesterase 1 (Tdp1) is one of the DNA repair system enzymes involved in the removal of DNA damages caused by topoisomerase I inhibitors. Thus, reducing the activity of Tdp1 can increase the effectiveness of currently used anticancer drugs. We describe here a new class of semisynthetic small molecule Tdp1 inhibitors based on the bile acid scaffold that were originally identified by virtual screening. The influence of functional groups of bile acids (hydroxy and acetoxy groups in the steroid framework and amide fragment in the side chain) on inhibitory activity was investigated. In vitro studies demonstrate the ability of the semisynthetic derivatives to effectively inhibit Tdp1 with IC50 up to 0.29 µM. Furthermore, an excellent fit is realized for the ligands when docked into the active site of the Tdp1 enzyme

    Glycyrrhetinic acid and its derivatives as inhibitors of poly(ADP-ribose)polymerases 1 and 2, apurinic/apyrimidinic endonuclease 1 and DNA polymerase β

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    Aim. For strengthening the efficiency of monofunctional alkylating antineoplastic drugs it is important to lower the capacity of base excision repair (BER) system which corrects the majority of DNA damages caused by these reagents. The objective was to create inhibitors of the key BER enzymes (PARP1, PARP2, DNA polymerase β, and APE1) by the directed modification of glycyrrhetinic acid (GA). Methods. Amides of GA were produced from the GA acetate by formation of the corresponding acyl chloride, amidation with the appropriate amine and subsequent deacylation. Small library of 2-cyano substituted derivatives of GA methyl esters was obtained by the structural modification of GA framework and carboxylic acid group. The inhibitory capacity of the compounds was estimated by comparison of the enzyme activities in specific tests in the presence of compounds versus their absence. Results. None of tested compounds inhibits PARP1 significantly. Unmodified GA and its morpholinic derivative were shown to be weak inhibitors of PARP2. The derivatives of GA containing keto-group in 11 triterpene framework were shown to be moderate inhibitors of pol β. Compound 3, containing 12-oxo-9(11)-en moiety in the ring C, was shown to be a single inhibitor of APE1 among all compounds studied. Conclusions. The class of GA derivatives, selective pol β inhibitors, was found out. The selective inhibitor of APE1 and weak selective inhibitor of PARP2 were also revealed

    Innovative model of deck electric scooter

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    У роботі виконано розробку дизайнерського концепту, створення інноваційної конструкції деки електросамокату та її розрахунок, що дозволило отримати необхідну інформацію щодо вибору матеріалу.The work involved the development of a design concept, the creation of an innovative design of the deck of an electric scooter and its calculation, which made it possible to obtain the necessary information regarding the choice of material

    DETERMINATION OF THE STABILITY OF A LOCAL ANESTHETIC BROMOKAIN TRANSDERMAL THERAPEUTIC SYSTEM

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    Aim. To study the stability of biocompatible microemulsion composition-based bromokain transdermal therapeutic systems (TTS) in order to confi rm the original shelf life and to identify the most appropriate TTS composition for storage.Materials and methods. The stability test using accelerated aging method was performed on the samples of TTS containing 50 and 100 mg of bromokain. Physicochemical properties of TTS were analyzed at the end of the 1st, 2nd, 3rd, and 6th month of storage. The physical confi guration of the dosage form, the content of bromokain in TTS, and drug release were evaluated at each stage of the study. The content of bromokain in the samples was recorded using high performance liquid chromatography (HPLC). As a control for each method, the newly manufactured TTS forms were used.Results. Unlike the samples containing 50 mg of bromokain, TTS with 100 mg of the anesthetic demonstrated changes in the physical confi guration and deterioration of the functional properties after the 6th month of storage. The quantitative content of the substance in TTS containing 50 and 100 mg of bromokain met the requirements of regulatory documentation (RD) at allphases of the experiment and was within 50,0 ± 5,0 mg and 100,0 ± 10,0 mg, respectively. The release profi le of TTS with 50 mg of bromokain has remained unchanged during storage and complies with the RD. TTS with 100 mg of bromokain after the 3rd month of storage had a deviation from the release profi le indicated in the RD.Conclusion. The shelf life of 2 years at t = 25 °C preset by us for samples of TTS containing 50 mg of bromokain has been confi rmed. According to the test results, samples of TTS with the content of bromokain of 100 mg were declared unstable and unfi t for storage under the selected storage conditions

    Superficial radially resolved fluorescence and 3D photochemical time-dependent model for photodynamic therapy

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    Photodynamic therapy (PDT) dosimetric tools are crucial for treatment planning and noninvasive monitoring by means of fluorescence. Present approaches consider usually a 1D problem, a simple photochemical process, or a spatially homogeneous photosensitizer. In this work, a radially resolved superficial photosensitizer fluorescence and 3D photochemical time-dependent PDT model are presented. The model provides a time-dependent estimation of tissue fluorescence and the photosensitizer and singlet oxygen 3D concentrations. The model is applied to a basal cell carcinoma treated by Metvix topical photosensitizer protocol. The analysis shows the potentiality in treatment planning and monitoring. The fluorescence results are in agreement with previous measurements
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