15,673 research outputs found

    Photonic circuits for generating modal, spectral, and polarization entanglement

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    We consider the design of photonic circuits that make use of Ti:LiNbO3_{3} diffused channel waveguides for generating photons with various combinations of modal, spectral, and polarization entanglement. Down-converted photon pairs are generated via spontaneous optical parametric down-conversion (SPDC) in a two-mode waveguide. We study a class of photonic circuits comprising: 1) a nonlinear periodically poled two-mode waveguide structure, 2) a set of single-mode and two-mode waveguide-based couplers arranged in such a way that they suitably separate the three photons comprising the SPDC process, and, for some applications, 3) a holographic Bragg grating that acts as a dichroic reflector. The first circuit produces frequency-degenerate down-converted photons, each with even spatial parity, in two separate single-mode waveguides. Changing the parameters of the elements allows this same circuit to produce two nondegenerate down-converted photons that are entangled in frequency or simultaneously entangled in frequency and polarization. The second photonic circuit is designed to produce modal entanglement by distinguishing the photons on the basis of their frequencies. A modified version of this circuit can be used to generate photons that are doubly entangled in mode number and polarization. The third photonic circuit is designed to manage dispersion by converting modal, spectral, and polarization entanglement into path entanglement

    Statistical Properties of the log-cosh Loss Function Used in Machine Learning

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    This paper analyzes a popular loss function used in machine learning called the log-cosh loss function. A number of papers have been published using this loss function but, to date, no statistical analysis has been presented in the literature. In this paper, we present the distribution function from which the log-cosh loss arises. We compare it to a similar distribution, called the Cauchy distribution, and carry out various statistical procedures that characterize its properties. In particular, we examine its associated pdf, cdf, likelihood function and Fisher information. Side-by-side we consider the Cauchy and Cosh distributions as well as the MLE of the location parameter with asymptotic bias, asymptotic variance, and confidence intervals. We also provide a comparison of robust estimators from several other loss functions, including the Huber loss function and the rank dispersion function. Further, we examine the use of the log-cosh function for quantile regression. In particular, we identify a quantile distribution function from which a maximum likelihood estimator for quantile regression can be derived. Finally, we compare a quantile M-estimator based on log-cosh with robust monotonicity against another approach to quantile regression based on convolutional smoothing.Comment: 10 pages, 17 figure

    Locked nucleic acid oligomers as handles for single molecule manipulation.

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    Single-molecule manipulation (SMM) techniques use applied force, and measured elastic response, to reveal microscopic physical parameters of individual biomolecules and details of biomolecular interactions. A major hurdle in the application of these techniques is the labeling method needed to immobilize biomolecules on solid supports. A simple, minimally-perturbative labeling strategy would significantly broaden the possible applications of SMM experiments, perhaps even allowing the study of native biomolecular structures. To accomplish this, we investigate the use of functionalized locked nucleic acid (LNA) oligomers as biomolecular handles that permit sequence-specific binding and immobilization of DNA. We find these probes form bonds with DNA with high specificity but with varied stability in response to the direction of applied mechanical force: when loaded in a shear orientation, the bound LNA oligomers were measured to be two orders of magnitude more stable than when loaded in a peeling, or unzipping, orientation. Our results show that LNA provides a simple, stable means to functionalize dsDNA for manipulation. We provide design rules that will facilitate their use in future experiments

    Counting the ions surrounding nucleic acids.

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    Nucleic acids are strongly negatively charged, and thus electrostatic interactions-screened by ions in solution-play an important role in governing their ability to fold and participate in biomolecular interactions. The negative charge creates a region, known as the ion atmosphere, in which cation and anion concentrations are perturbed from their bulk values. Ion counting experiments quantify the ion atmosphere by measuring the preferential ion interaction coefficient: the net total number of excess ions above, or below, the number expected due to the bulk concentration. The results of such studies provide important constraints on theories, which typically predict the full three-dimensional distribution of the screening cloud. This article reviews the state of nucleic acid ion counting measurements and critically analyzes their ability to test both analytical and simulation-based models

    Optimal design of water distribution systems based on entropy and topology

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    A new multi-objective evolutionary optimization approach for joint topology and pipe size design of water distribution systems is presented. The algorithm proposed considers simultaneously the adequacy of flow and pressure at the demand nodes; the initial construction cost; the network topology; and a measure of hydraulic capacity reliability. The optimization procedure is based on a general measure of hydraulic performance that combines statistical entropy, network connectivity and hydraulic feasibility. The topological properties of the solutions are accounted for and arbitrary assumptions regarding the quality of infeasible solutions are not applied. In other words, both feasible and infeasible solutions participate in the evolutionary processes; solutions survive and reproduce or perish strictly according to their Pareto-optimality. Removing artificial barriers in this way frees the algorithm to evolve optimal solutions quickly. Furthermore, any redundant binary codes that result from crossover or mutation are eliminated gradually in a seamless and generic way that avoids the arbitrary loss of potentially useful genetic material and preserves the quality of the information that is transmitted from one generation to the next. The approach proposed is entirely generic: we have not introduced any additional parameters that require calibration on a case-by-case basis. Detailed and extensive results for two test problems are included that suggest the approach is highly effective. In general, the frontier-optimal solutions achieved include topologies that are fully branched, partially- and fully-looped and, for networks with multiple sources, completely separate sub-networks

    Measuring the Impact of Higher Education in Promoting Sustainable Development Goals: Analysis of the Arab universities’ performance

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    Sustainability's global importance has amplified the role of universities in achieving the UN Sustainable Development Goals (SDGs) through research, education, and community engagement. Aim: This study aims to provide valuable insights into the role of Arab universities in promoting sustainability within the context of global higher education. Approach and methods: This study analyzes the performance of 200 universities from 15 Arab countries in the THE IMPACT Rankings. Their performance was compared to 135 universities from three of the leading world-class higher education systems: Canada, UK, and USA. Results: A global demand for sustainable development, Arab universities face challenges in improving their contributions to the SDGs and sustainability rankings. Despite the impressive growth in the participation of Arab universities in THE IMPACT Rankings yet lags in quality and impact of Arab universities contributions towards SDGs. Conclusion: The policy implications underscore the importance of institutional commitment to sustainability in Arab universities, urging the alignment of policies, funding, and curriculum with the United Nations Sustainable Development Goals (SDGs). Arab universities need to bridge performance gaps, promote green initiatives, and contribute effectively to the achievement of SDGs while recognizing the diverse socio-economic context and priorities of the Arab region.Globalne znaczenie zrównoważonego rozwoju spotęgowało rolę uniwersytetów w realizacji Celów Zrównoważonego Rozwoju (SDG) ONZ poprzez badania, edukację i zaangażowanie społeczności. Cel: Celem tego badania jest dostarczenie cennych spostrzeżeń dotyczących roli uniwersytetów arabskich w promowaniu zrównoważonego rozwoju w kontekście globalnego szkolnictwa wyższego. Podejście i metody: Badanie to analizuje wyniki 200 uniwersytetów z 15 krajów arabskich w rankingach THE IMPACT. Ich wyniki porównano z 135 uniwersytetami z trzech czołowych światowych systemów szkolnictwa wyższego: Kanady, Wielkiej Brytanii i USA. Wyniki: W obliczu globalnego zapotrzebowania na zrównoważony rozwój, uniwersytety arabskie napotykają wyzwania w poprawie swojego wkładu w SDG i rankingi zrównoważoności. Pomimo imponującego wzrostu udziału uniwersytetów arabskich w rankingach THE IMPACT, jest jeszcze wiele do zrobienia w zakresie jakości i wpływu ich wkładu w SDG. Wnioski: Implikacje polityczne podkreślają znaczenie zobowiązania instytucjonalnego do zrównoważonego rozwoju w uniwersytetach arabskich, nawołując do dostosowania polityk, finansowania i programów nauczania do Celów Zrównoważonego Rozwoju (SDG) ONZ. Uniwersytety arabskie muszą zniwelować luki w wynikach, promować inicjatywy zielone i efektywnie przyczyniać się do osiągnięcia SDG, uwzględniając różnorodny kontekst społeczno-ekonomiczny i priorytety regionu arabskiego. &nbsp

    Development and Evaluation of Acoustic Sound Absorption Composite from Orange Peels Residues and Sachet Water Bags

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    The goal of this study was produce a device that would reduce the unwanted sound/noise produced by machines encountered in our daily activities using orange peels (agricultural residues) and sachet water bags. These materials were prepared, mixed in 70:30 % ratio and transferred into a two-roll mill (compounding machine), where they were melted at about 150oC temperature before transferring them to a compressing machine that was set at a lower temperature of 130oC. The composite panel was coupled together to form a box where three speakers were connected to MP3 and inserted into the box. Test was carried out to check for the sound absorption levels of the composite using a sound level meter. Results obtained show that ‘A’ weighing filter covers the full frequency range of 0–90 kHz before coupling the absorption box. This could irreversibly damage the auditory system since it fell outside the acceptable range of 0–80 dB frequency sensitivity of human ear. However, the sound level becomes within the acceptable frequency when coupled to the developed absorption box indicating that the composite board using orange peels and empty water sachet is a good sound absorber
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