Multifractal Analysis for the Dynamical Heterogeneity in Strongly Correlated Many-Body Systems

By calculating the non-equilibrium parameter of the probability distribution function and the singularity spectrum of multifractal we have quantified the dynamical heterogeneity in strongly correlated many-body systems

The Connection between Organizational and National Cultures

National and organizational cultures have a cross-level influence on organizations and their management practices. Given such an impact of two cultures, the relation between national and organizational cultures has attracted the interest of researchers. Since organizations and their organizational cultures are nested and clustered within a nation and its societal culture, intuitively, it appears that national culture is connected to organizational culture. However, the connection between the two cultures is not as simple as believed. There are two perspectives regarding the relation between national and organizational culture : the “culture affecting culture” versus the “no effect” perspectives. There are various types of organizational culture, such as hierarchy, clan, market, and adhocracy. I explore and theorize the relation between national culture dimensions and these types of organizational culture in order to advance knowledge on such a relation. Then, I predict in what regions a type of organizational culture is most likely to develop

センコウセイ フクマクエン デ ハッショウ シタ ショウチョウ gastrointestinal stromal tumor ノ 1レイ

We report a case of gastrointestinal stromal tumor (GIST) with perforation in the jejunum and peritoneal dissemination. A 64 year-old man admitted our hospital with severe abdominal pain. He had findings of panperitonitis and the abdominal CT examination revealed free air and an intraabdominal abscess. We suspected perforation of the small intestine and operated. There were two adjacent tumors (6cm in diameter each) of the jejunum and peritoneal dissemination, and one of them was perforated. We performed a jejunojejunostomy and resected as all disseminated tumors as possible. Histopathological findings showed that the tumors were composed of spindle cell proliferation with three or four mitoses per high-power fields (HPF). Because tumor cell were positive for c-kit and CD34, and negative for alpha-smooth muscle actin and S-100 immunohistochemically, we diagnosed these tumors as “maligmant GIST of small intestine, uncommitted type”. Perforation of GIST is rare. Only 20 cases of GIST with peritonitis due to perforation have been reported in Japan, including the present case. Of 20 cases, 14 were small intestinal GIST. Small intestinal GIST should be recognized as a high-risk group of malignancy and perforation

ダイチョウ ガン ニ タイスル 5 FU アイソボリン リョウホウ デ コウカ ガ ミトメラレタ 2レイ

We report 2 cases of rectal cancer responding to postoperative chemotherapy with 5-fluorouracil and isovorin. Case 1 : A 60 years-old woman underwent low-anterior resection for rectal cancer in 1994 and partial right lung resection for metastatic lung cancer in 1998. She underwent chemotherapy with 5-fluorouracil and isovorin for mediastinal lymph node metastasis and high score of serum CEA in 2000. After the chemotherapy, the lymph node shrank and serum CEA normalized. Case 2 : A 75 years-old woman underwent low-anterior resection and hysterectomy for rectal cancer with multiple lung metastasis in 2000. She underwent postoperative chemotherapy with 5-fluorouracil and isovorin for metastatic lung cancer. The lung tumor shrank and serum CEA decreased. Chemotherapy with 5-fluorouracil and isovorin seemed to be effective for advanced colon cancer. We should reconfirm the effectiveness and improve the directions for use

ジョウチョウカンマク ジョウミャク ケッセンショウ ノ イチレイ

We report a case of superior mesenteric vein thrombosis successfully saved by resection of enteral necrosis. A ６７ years-old man who admitted for abdominal pain was diagnosed with acute enterocolitis and treated. After two days, abdominal pain increased and abdominal CT revealed superior mesenteric vein thrombosis. He was referred to the department of surgery. We conducted emergency operation. During surgery, bloody ascites and the enteral necrosis about５０cm in length was confirmed. The necrotic ileum was resected and an end-to-end anastomosis was performed. Immediately after surgery, we started anticoagulation therapy. The patient recoverd well and was discharged on POD３２． In a slow pattern like this case, we should suspect superior mesenteric vein thrombosis and diagnose by abdominal CT

Serological Surveillance Development for Tropical Infectious Diseases Using Simultaneous Microsphere-Based Multiplex Assays and Finite Mixture Models

Background:A strategy to combat infectious diseases, including neglected tropical diseases (NTDs), will depend on the development of reliable epidemiological surveillance methods. To establish a simple and practical seroprevalence detection system, we developed a microsphere-based multiplex immunoassay system and evaluated utility using samples obtained in Kenya.Methods:We developed a microsphere-based immuno-assay system to simultaneously measure the individual levels of plasma antibody (IgG) against 8 antigens derived from 6 pathogens: Entamoeba histolytica (C-IgL), Leishmania donovani (KRP42), Toxoplasma gondii (SAG1), Wuchereria bancrofti (SXP1), HIV (gag, gp120 and gp41), and Vibrio cholerae (cholera toxin). The assay system was validated using appropriate control samples. The assay system was applied for 3411 blood samples collected from the general population randomly selected from two health and demographic surveillance system (HDSS) cohorts in the coastal and western regions of Kenya. The immunoassay values distribution for each antigen was mathematically defined by a finite mixture model, and cut-off values were optimized.Findings:Sensitivities and specificities for each antigen ranged between 71 and 100%. Seroprevalences for each pathogen from the Kwale and Mbita HDSS sites (respectively) were as follows: HIV, 3.0% and 20.1%; L. donovani, 12.6% and 17.3%; E. histolytica, 12.8% and 16.6%; and T. gondii, 30.9% and 28.2%. Seroprevalences of W. bancrofti and V. cholerae showed relatively high figures, especially among children. The results might be affected by immunological cross reactions between W. bancrofti-SXP1 and other parasitic infections; and cholera toxin and the enterotoxigenic E. coli (ETEC), respectively.Interpretation:A microsphere-based multi-serological assay system can provide an opportunity to comprehensively grasp epidemiological features for NTDs. By adding pathogens and antigens of interest, optimized made-to-order high-quality programs can be established to utilize limited resources to effectively control NTDs in Africa

Cytological studies on the exudates formed with the application of Usguentum Vesicans Part Ⅲ. Studies on the exudate in patients with chronic leukemia

Cellular reactions were studied through an investigation of cellular aspects of exudate formed with the application of Unguentum Vesicans to patients with chronic ieukemia.　Following are the results. 1. As compared with normal controls, some delay was noted in the onset of blister formation and numbers of cells were less, but the decrease was not so remarkable as in acute leukemia. 2. Usually, the cells consist mostly of polymorphonuclear neutrophils, and in addition a few lymphocytes, monocytes, staff neutrophils, eosinophils, and basophils were noted. In chronic myelogenous leukemia, basophils were noted in higher percentage. 3. The average numbers of nucleus segmentation of the neutrophils were about the same as in normal controls. 4. In chronic myelogenous leukemia, wandering velocity of the neutrophils was decreased as compared with normal controls, but the decrease was not so remarkable as in acute leukemia. In chronic lymphocytic leukemia, the velocity was about the same as in normal controls. 5. In chronic myelogenous leukemia, cell numbers and wandering velocity of the neutrophils were remarkably increased during remissions as compared with the pre-treatment period

Cytological studies on the exudates formed with the application of Unguentum Vesicans. Part Ⅰ. In normal coutrols

In order to study the defense reaction of the body to a local infection, an investigation was made for cellular aspects of exudate formed with the application of Unguentum Vesicans. Followings are the results. 1. The onset of blister formation averaged 8,7 hours following the application of Unguentum Vesicans. 2. Apperance of cells was noted with an increase of the exudate following blister formation. Numbers of cells in the exudate in 12 cases 1,3,6 and 12 hours following the onset of blister formation averaged 1,037, 1,481, 1,245, and 2,083 respectively. 3. The cells conist mostly of polymorphonuclear neutrophils, and in addition a few lymphocytes, monocytes, eosinophils, and staff neutrophils were noted. 4. The average numbers of nucleus segmentation of the neutrophils in 12 cases 1,3,6, and 12 hours following the onset of blister formation were 2.85, 3-08, 3.14, and 3.32 respectively, showing a constant increase with passage of time. 5. Wandering velocity of the neutrophils in 12 cases 1,3,6, and 12 hours following the onset of blister formation averaged 10.04μ/min, 12.57μ/min, 10.76μ/min, and 11.06μ/min respectively, showing a relatively active movement constantly. 6. An investigation of the exudate formed with the application of Unguentum Vesicans has a merit in that calculation of cell numbers and measurement of the wandering velocity can be performed with ease