Political parties and social networks in Iraq, 1908-1920

Sakai, Kelko; Political Parties and Social Networks in Iraq, 1908-1920; submitted for M.A. in Faculty of Social Sciences. C.M.E.I.S.; 1994 This study is to analyze the principal patterns of proto-nationalism as they emerged in the anti-colonial movement in the first two decades of twentieth century. The earliest party political activities were based on notions of Arab separatism from the Ottoman Empire and on anti-Western attitudes on the part of some religious Shi'i. On the eve of the award of the mandate for Iraq to Britain, two major political parties were actively opposed to the British occupation, and this opposition found expression in the country-wide uprising in 1920.At this stage Iraqi nationalism, in the sense of both qawmiya and wataniya. was only at a very early stage of development. The popularity and breadth of the uprising was largely due to its being based on a combination of existing social networks, and the way in which it acted as a focus for proto-national and anti-colonial sentiments. Haras al-Istiqlal succeeded in mobilizing 'traditional society' and managed at least in part to overcome tribal, religious, sectarian and urban/ rural differences, especially with a support it attracted from Shi'i "ulama and sada'. al-'Ahd al-'Iraqi. on the other hand, originally established as an 'Arabist' society by former Ottoman officers, also tried to mobilize tribal society, mainly in northern Iraq, after becoming separated from its Syrian- based founders. This caused antagonisms between the organization’s headquarters in Damascus and tribal and other local political forces in Iraq. Both parties attempted to mobilize sentiments which can be described loosely as 'Iraqist'. Although the idea of Iraqi wataniya was still vague in 1920, this early expression of Iraqism as a proto-nationalist force has functioned as a source for reproduction and the imagining of Iraqi national identity

Accuracy of Articulation Rate Control with Visual Feedback in Persons who do and do not Stutter

AbstractThe ability to control speech rate with real-time visual feedback was compared between people who do and do not stutter (PWS/PWNS). Nine PWS and 7 PWNS participated in the study. Fifteen sentences were read aloud after repeating a played-back sentence twice in each of 6 trials at 6 different target speeds. The 6 trials comprise a session, and there were 3 sessions (A1, B, A2) with only the second session (B) accompanied by real-time visual feedback of the subject's speech rate and the target speed. The speech rate excluding pauses or dysfluencies was significantly reduced in B and A2 from that in session A1. Although there was no difference in speech rate between B and A2, (a) there was an interaction between the target rate and the group in session B, and (b) the variability in the error of the PWS was larger than that of the PWNS in the retention session (A2). These results suggests (a) that at least some of the PWS use a different strategy in controlling their speech rate than PWNS, and (b) that some of the PWS were less accurate in retaining the learned speech rate in the previous session B with visual feedback than the PWNS, although they did use the visual feedback information and learned the speech rate, to a similar averaged accuracy during the feedback

Transcription factor scleraxis vitally contributes to progenitor lineage direction in wound healing of adult tendon in mice

Tendon is a dense connective tissue that transmits high mechanical forces from skeletal muscle to bone. The transcription factor scleraxis (Scx) is a highly specific marker of both precursor and mature tendon cells (tenocytes). Mice lacking scx exhibit a specific and virtually complete loss of tendons during development. However, the functional contribution of Scx to wound healing in adult tendon has not yet been fully characterized. Here, using ScxGFP-tracking and loss-of-function systems, we show in an adult mouse model of Achilles tendon injury that paratenon cells, representing a stem cell antigen-1 (Sca-1)–positive and Scx-negative progenitor subpopulation, display Scx induction, migrate to the wound site, and produce extracellular matrix (ECM) to bridge the defect, whereas resident tenocytes exhibit a delayed response. Scx induction in the progenitors is initiated by transforming growth factor β (TGF-β) signaling. scx-deficient mice had migration of Sca-1–positive progenitor cell to the lesion site but impaired ECM assembly to bridge the defect. Mechanistically, scx-null progenitors displayed higher chondrogenic potential with up-regulation of SRY-box 9 (Sox9) coactivator PPAR-γ coactivator-1α (PGC-1α) in vitro, and knock-in analysis revealed that forced expression of full-length scx significantly inhibited Sox9 expression. Accordingly, scx-null wounds formed cartilage-like tissues that developed ectopic ossification. Our findings indicate a critical role of Scx in a progenitor-cell lineage in wound healing of adult mouse tendon. These progenitor cells could represent targets in strategies to facilitate tendon repair. We propose that this lineage-regulatory mechanism in tissue progenitors could apply to a broader set of tissues or biological systems in the body

14-3-3 theta binding to cell cycle regulatory factors is enhanced by HIV-1 Vpr

<p>Abstract</p> <p>Background</p> <p>Despite continuing advances in our understanding of AIDS pathogenesis, the mechanism of CD4+ T cell depletion in HIV-1-infected individuals remains unclear. The HIV-1 Vpr accessory protein causes cell death, likely through a mechanism related to its ability to arrest cells in the G₂,M phase. Recent evidence implicated the scaffold protein, 14-3-3, in Vpr cell cycle blockade.</p> <p>Results</p> <p>We found that in human T cells, 14-3-3 plays an active role in mediating Vpr-induced cell cycle arrest and reveal a dramatic increase in the amount of Cdk1, Cdc25C, and CyclinB1 bound to 14-3-3 θ during Vpr_v-induced G₂,M arrest. By contrast, a cell-cycle-arrest-dead Vpr mutant failed to augment 14-3-3 θ association with Cdk1 and CyclinB1. Moreover, G₂,M arrest caused by HIV-1 infection strongly correlated with a disruption in 14-3-3 θ binding to centrosomal proteins, Plk1 and centrin. Finally, Vpr caused elevated levels of CyclinB1, Plk1, and Cdk1 in a complex with the nuclear transport and spindle assembly protein, importin β.</p> <p>Conclusion</p> <p>Thus, our data reveal a new facet of Vpr-induced cell cycle arrest involving previously unrecognized abnormal rearrangements of multiprotein assemblies containing key cell cycle regulatory proteins.</p> <p>Reviewers</p> <p>This article was reviewed by David Kaplan, Nathaniel R. Landau and Yan Zhou.</p

Study regarding the Proficiency of Nursing Teacher and Stressor : Targeting Nursing Teachers at Special Technical Schools

取得学位 : 博士（保健学）, 学位授与番号 : 医博甲第1860号 , 学位授与年月日 : 平成19年3月22日, 学位授与大学 : 金沢大学, 審査結果の報告日 : 平成19年2月20日, 主査 : 稲垣 美智子 , 副査 :坂井 明美, 須釜 淳