MANFAAT EKSTRAKURIKULER JURNALISTIK BAGI PENGEMBANGAN KEBAHASAAN SISWA KELAS XI SMA FQI KEFAMENANU

Program pelatihan jurnalistik yang bertempat di SMAK Fides Quaerens Intellectum (FQI) Kefanenanu, Kelurahan Sasi, Kecamatan Kota Kefamenanu, Kabupaten Timor Tengah Utara (TTU), Provinsi Nusa Tenggara Timur ini, diluncurkan melalui program Pengabdian kepada Masyarakat (PkM).  Kegiatan ini bertujuan untuk melatih 30 siswa kelas XI untuk terampil menulis berita yang dimuat pada majalah dinding sekolah tersebut. Pelaksanaan PkM ini dilakukan dengan metode sosialisasi, cermah, pelatihan (workshop), dan bimbingan. Usai memberikan pelatihan, para siswa disodorkan dengan sebuah kuesioner yang memuat 10 pertanyaan untuk mengetahui persepsi mereka terhadap manfaat bagi pengembangan kebahasaan dari pelatihan tersebut. Jawaan mereka dianalisis dengan mengggunakan deskriptif kualitatif yaitu jumlah jawaban diagi dengan jumlah siswa dikali dengan 100%. Hasil analisis data menunjukkan bahwa terapat 297 (atau 99%) respon, yang tersebar pada opsi sangat setuju 81 (27%), setuju 175 (58%), kurang setuju 39 (13%), tidak setuju 1 (atau 0,3%) dan sangat tidak setuju 1 (atau 0,3%). Respon ini menunjukkan bahwa kegiatan ektrakurikuler jurnalistik menumbuhkan kemampuan akademik kebahasaan mereka. Ini menunjukkan bahwa kegiatan jurnalistik perlu dikembangkan terus agar kualitas kemampuan kebahasaan siswa terus meningkat

Konversi Biji Alpukat Menjadi Bio-oil dengan Metode Pyrolisis Menggunakan Katalis Zeolit Alam

The trend of fossil fuel demand is always increase by time in the world. Yet, petroleum oil as a non-renewable has been declining each year. It is necessary to find a new alternative fuel that can be renewed, such as to applied biomasses as resources energy. One of several potential biomasses can be converted to energy or bio-oil is the seed of an avocado because it's contain so high fat fatty acid (FFA). This seed has not been used maximacally yet, so in this research this seed is converted into bio-oil by using pyrolysis method and natural zeolite as a catalyst. The purpose of this research is to get the highest yield of bio-oil by applied variation of ratio sample : catalyst (50:0, 50:1, 50:2, 50:3 g/g), and temperature variation of pyrolysis process is 270, 300, 330 ºC. Based on results in this research, the highest of bio-oil is 79,08 % found under condition ratio sampel : catalyst 50 :2 and pyrolysis temperature is 330 ºC. The bio-oil is analyzed and it's density 0.988 g/ml, viscosity 7,560 cSt, acid value 0,1002 mg NaOH/ g sample, flash point 56 ºC and heating value 17,354 MJ/kg. Based on GC-MS analyzed bio-oil were contained (2,4,4-trimethyl-2-pentene), (3,4,4-trimethyl-2- pentene), (Diisobutylene), (2,4,4-trimethyl-3-pentene) and (2-methyl-trimer- propene) with peak area (7,84%), (7,82%), (5,69%), (3,82%) and (3,58%)

A cohort analysis of patients receiving neoadjuvant androgen deprivation therapy prior to robot-assisted laparoscopic prostatectomy during the Covid-19 pandemic

Objectives: The purpose of this study was to investigate localised prostate cancer treated with or without neoadjuvant androgen deprivation therapy prior to robot-assisted laparoscopic prostatectomy, and the impact of Covid-19 treatment disruption, on clinico-pathologic outcomes. Patients and methods: Data was retrospectively collected from 124 consecutive patients treated with robot-assisted laparoscopic prostatectomy between November 2019–September 2020. Sixty-two patients were treated before 13 March 2020 (historic cohort) and 62 afterwards (covid cohort). Thirty-seven patients in the covid cohort additionally received neoadjuvant androgen deprivation therapy (mean duration of 3 months) consisting of bicalutamide 150 mg once a day for 4 weeks, with leuprolide 3.75 mg monthly injections commencing after week 1, up until the date of surgery. Results: Statistical analysis found no difference in peri-operative measures and length of stay for patients treated with or without neoadjuvant androgen deprivation therapy. Patients with delayed surgical treatment offered neoadjuvant androgen deprivation therapy showed a trend towards a reduction in positive surgical margins (p=0.134), N1 disease (p=0.424) and pathological down-staging (50% patients with pT2 disease). Patients within the covid cohort experienced significantly increased detectable prostate-specific antigen levels (p<0.007). Conclusion: Our study demonstrated that a three-month duration of neoadjuvant androgen deprivation therapy prior to robot-assisted laparoscopic prostatectomy may improve pathological outcomes but this time-frame is inadequate to influence detectable prostate-specific antigen levels. Covid-19-related treatment delays led to significantly increased detectable prostate-specific antigen levels. Level of evidence: 2b

Three-Dimensional Characterization of Mechanical Interactions between Endothelial Cells and Extracellular Matrix during Angiogenic Sprouting

We studied the three-dimensional cell-extracellular matrix interactions of endothelial cells that form multicellular structures called sprouts. We analyzed the data collected in-situ from angiogenic sprouting experiments and identified the differentiated interaction behavior exhibited by the tip and stalk cells. Moreover, our analysis of the tip cell lamellipodia revealed the diversity in their interaction behavior under certain conditions (e.g., when the heading of a sprout is switched approximately between the long-axis direction of two different lamellipodia). This study marks the first time that new characteristics of such interactions have been identified with shape changes in the sprouts and the associated rearrangements of collagen fibers. Clear illustrations of such changes are depicted in three-dimensional views.Singapore-MIT Alliance in Research and Technology (SMART

Ruthenium oxide-carbon-based nanofiller-reinforced conducting polymer nanocomposites and their supercapacitor applications.

In this review article, we have presented for the first time the new applications of supercapacitor technologies and working principles of the family of RuO2-carbon-based nanofiller-reinforced conducting polymer nanocomposites. Our review focuses on pseudocapacitors and symmetric and asymmetric supercapacitors. Over the last years, the supercapacitors as a new technology in energy storage systems have attracted more and more attention. They have some unique characteristics such as fast charge/discharge capability, high energy and power densities, and long stability. However, the need for economic, compatible, and easy synthesis materials for supercapacitors have led to the development of RuO2-carbon-based nanofiller-reinforced conducting polymer nanocomposites with RuO2. Therefore, the aim of this manuscript was to review RuO2-carbon-based nanofiller-reinforced conducting polymer nanocomposites with RuO2 over the last 17 years

Phylogenetic Diversity and Ecological Pattern of Ammonia-oxidizing Archaea in the Surface Sediments of the Western Pacific

The phylogenetic diversity of ammonia-oxidizing archaea (AOA) was surveyed in the surface sediments from the northern part of the South China Sea (SCS). The distribution pattern of AOA in the western Pacific was discussed through comparing the SCS with other areas in the western Pacific including Changjiang Estuary and the adjacent East China Sea where high input of anthropogenic nitrogen was evident, the tropical West Pacific Continental Margins close to the Philippines, the deep-sea methane seep sediments in the Okhotsk Sea, the cold deep sea of Northeastern Japan Sea, and the hydrothermal field in the Southern Okinawa Trough. These various environments provide a wide spectrum of physical and chemical conditions for a better understanding of the distribution pattern and diversities of AOA in the western Pacific. Under these different conditions, the distinct community composition between shallow and deep-sea sediments was clearly delineated based on the UniFrac PCoA and Jackknife Environmental Cluster analyses. Phylogenetic analyses showed that a few ammonia-oxidizing archaeal subclades in the marine water column/sediment clade and endemic lineages were indicative phylotypes for some environments. Higher phylogenetic diversity was observed in the Philippines while lower diversity in the hydrothermal vent habitat. Water depth and possibly with other environmental factors could be the main driving forces to shape the phylogenetic diversity of AOA observed, not only in the SCS but also in the whole western Pacific. The multivariate regression tree analysis also supported this observation consistently. Moreover, the functions of current and other climate factors were also discussed in comparison of phylogenetic diversity. The information collectively provides important insights into the ecophysiological requirements of uncultured ammonia-oxidizing archaeal lineages in the western Pacific Ocean

Community shift of ammonia-oxidizing bacteria along an anthropogenic pollution gradient from the Pearl River Delta to the South China Sea

The phylogenetic diversity and abundance of ammonia-oxidizing beta-proteobacteria (beta-AOB) was analyzed along an anthropogenic pollution gradient from the coastal Pearl River Delta to the South China Sea using the ammonia monooxygenase subunit A (amoA) gene. Along the gradient from coastal to the open ocean, the phylogenetic diversity of the dominant genus changed from Nitrosomonas to Nitrosospira, indicating the niche specificity by these two genera as both salinity and anthropogenic influence were major factors involved. The diversity of bacterial amoA gene was also variable along the gradient, with the highest in the deep-sea sediments, followed by the marshes sediments and the lowest in the coastal areas. Within the Nitrosomonas-related clade, four distinct lineages were identified including a putative new one (A5-16) from the different sites over the large geographical area. In the Nitrosospira-related clade, the habitat-specific lineages to the deep-sea and coastal sediments were identified. This study also provides strong support that Nitrosomonas genus, especially Nitrosomonas oligotropha lineage (6a) could be a potential bio-indicator species for pollution or freshwater/wastewater input into coastal environments. A suite of statistical analyses used showed that water depth and temperature were major factors shaping the community structure of beta-AOB in this study area

Impact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries

Background: Balancing opioid stewardship and the need for adequate analgesia following discharge after surgery is challenging. This study aimed to compare the outcomes for patients discharged with opioid versus opioid-free analgesia after common surgical procedures.Methods: This international, multicentre, prospective cohort study collected data from patients undergoing common acute and elective general surgical, urological, gynaecological, and orthopaedic procedures. The primary outcomes were patient-reported time in severe pain measured on a numerical analogue scale from 0 to 100% and patient-reported satisfaction with pain relief during the first week following discharge. Data were collected by in-hospital chart review and patient telephone interview 1 week after discharge.Results: The study recruited 4273 patients from 144 centres in 25 countries; 1311 patients (30.7%) were prescribed opioid analgesia at discharge. Patients reported being in severe pain for 10 (i.q.r. 1-30)% of the first week after discharge and rated satisfaction with analgesia as 90 (i.q.r. 80-100) of 100. After adjustment for confounders, opioid analgesia on discharge was independently associated with increased pain severity (risk ratio 1.52, 95% c.i. 1.31 to 1.76; P < 0.001) and re-presentation to healthcare providers owing to side-effects of medication (OR 2.38, 95% c.i. 1.36 to 4.17; P = 0.004), but not with satisfaction with analgesia (beta coefficient 0.92, 95% c.i. -1.52 to 3.36; P = 0.468) compared with opioid-free analgesia. Although opioid prescribing varied greatly between high-income and low- and middle-income countries, patient-reported outcomes did not.Conclusion: Opioid analgesia prescription on surgical discharge is associated with a higher risk of re-presentation owing to side-effects of medication and increased patient-reported pain, but not with changes in patient-reported satisfaction. Opioid-free discharge analgesia should be adopted routinely

Gastric lavage with normal saline: Effects on serum electrolytes

PubMedID: 20586149Objective: The aim of this study is to determine the intensity of changes in serum calcium, ionized calcium, and magnesium levels after gastric lavage with normal saline in patients with amitriptyline intoxication. Material and methods: In this study, thirty patients older than 16 years with the history of intoxication with amitriptyline were included. After the baseline serum calcium, ionized calcium, and magnesium levels had been measured, gastric lavage with normal saline was performed. Serum levels of calcium, ionized calcium, and magnesium were monitored at 15 minutes, 6 hours, and 12 hours. Results: Serum calcium levels decreased significantly from 9.32±0.47 mg/dL to 8.40±0.61 mg/dL (15 minutes, p<0.001), 8.92±0.54 mg/dL (6 hours, p<0.001), and 8.93±0.54 mg/dL (12 hours, p<0.001). Serum ionized calcium levels decreased significantly from 1.26±0.10 mmol/L to 1.20±0.07 mmol/L (15 minutes, p=0.004), 1.21 ±0.08 mmol/L (6 hours, p=0.024), and 1.21 ±0.08 mmol/L (12 hours, p=0.034). Serum magnesium levels decreased from 2.41 ±0.43 mg/dL to 2.04±0.25 mg/dL (15 minutes, p<0.001), 2.14±0.26 mg/dL (6 hours, p<0.001), and 2.16±0.25 mg/dL (12 hours, p<0.001). Conclusion: Our study demonstrated that gastric lavage with normal saline can cause a statistically significant decrease in serum calcium, ionized calcium, and magnesium