263 research outputs found

    Mobbing as an organizational phenomenon impeding implementation of changes

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    Most of organizations in Russia are not ready to be changed in compliance with the requirements being dictated by outside environment. The relevance of the study is stipulated by the requirement for detection of causes impeding timely implementation of changes. The figures stated in the article are based on the inquiry held among working undergraduates in higher training of Kazan Federal University, participants in a course of Presidential Retraining Program for managerial staff, responsible executives and workforce of the enterprises in the Republic of Tatarstan. The present article makes an attempt to investigate the main forms and types of mobbing specific to Russia as well as its causes and consequences. Since mobbing has an adverse impact on implementing organizational reassignment the authors consider ways out of the situation of systematical moral persecution

    Role of government in innovational reforms of russian economy

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    This article is devoted to the problem of Russian economy innovational structure creation and maintaining. Authors point out, that building of innovational economy is possible only on the assumption of the government, political forces and business partnering mechanism efficiency. Those subjects have to closely collaborate, not confront each other, with clear differentiation of economic targets and responsibilities of all partners. General direction of the Russian economy social-economic structure reforming is its further maximal adaptation to the market of innovational products and services features. There is a necessity of task-oriented economical subjects, political and social groups retrieve aggregation with which will allow enhancing progressive Russian society forces influence to the basic economy development trend

    The balance of inorganic nitrogen in the basins of small rivers (On the example of the watershed Northern Dvina)

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    © 2016,International Journal of Pharmacy and Technology. All rights reserved.In article features of nitrogen circulation transformation as a result of influence of anthropogenous factor on the example of the small river basin of the river Northern Dvina are considered. Relevance of research is confirmed by a number of negative processes common to the present stage of humanity development over its expense caused by excess of nitrogen inflow to the biosphere. The method of balance which allows to objectively estimate a contribution of economic activity and extent of transformation of nitrogen circulation is the cornerstone of anthropogenous nitrogen component allocation. The structure analysis of received inorganic nitrogen balance part showed that 80 - 97% of the nitrogen amount arriving on reservoirs are the share of atmospheric precipitation. Even in the low-developed territories,with insignificant anthropogenous influence,the transformation of biogeochemical nitrogen circulation which is expressed in accumulation of this component is noted. The circulating air streams are the main distributors of nitrogen influencing its natural cycle. Thus,cross-border transfer of the polluting substances represents one of priority and relevant environmental problems of the present

    Benefits of project management at lean manufacturing tools implementation

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    © Canadian Center of Science and Education. The given article is devoted to reviewing the features of projects focused on implementation of lean manufacturing tools at the industrial enterprises. The study purpose is the statement of need to implement transformations in the field of lean manufacturing introduction (Lean-transformations) in the form of projects. The article introduces a concept of lean production project (Lean-project), the particular projects possessing the special aspects to be taken into consideration in the course of their implementation at various enterprises. The article demonstrates the benefits of Lean-transformations at applying the methods of project management. The key distinction of such projects is their result to be received upon completion. The result of the investment projects completion is to put into place a product or a service. The result of Lean-projects implementation is the introduction of lean manufacturing tools at the industrial enterprises to consequently obtain cost-effectiveness and a number of competitive advantages. Thus, the investment projects and Lean-projects are different in their constituent elements the study of which will make possible to formulate a system view of lean manufacturing project implementation. The article in general is focused on combination of two potent methodological frameworks-Project Management and Lean Manufacturing, each of which provides a means of obtaining significant benefits at their expert implementation and use. Combination of these is urged to provide multiplicative effect in the course of putting into practice the transformations at the industrial enterprises. However, to achieve the due effect it is necessary to be guided by the peculiar features of lean manufacturing projects what will necessarily call forth the correction of lean manufacturing methodological framework and derogation from stringent requirements of Lean Thinking concept

    Estimation procedure of industrial-engineering communication (IEC)

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    © Medwell Journals, 2016.This study has summarized some aspects of industrial-engineering communication estimation procedure. It has shown up faults of such effectiveness research methods as industrial analysis ratio forming part of the communication, game theory, input-output balancing. There has been proved the method industrial-engineering communication estimation procedure. The method consists of qualitative analysis of industrial-engineering communication and its effect on the level of transaction cost and enterprises value, effectiveness of such communication from the view of social and infrastructural development. Mathematical method is based on the functional analysis and calculating the flexibility of transaction cost function which are formed in the result of the industrial-engineering communication development

    A critical role of tropomyosins in TGF-beta regulation of the actin cytoskeleton and cell motility in epithelial cells

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    We have investigated transforming growth factor beta (TGF-beta)-mediated induction of actin stress fibers in normal and metastatic epithelial cells. We found that stress fiber formation requires de novo protein synthesis, p38Mapk and Smad signaling. We show that TGF-beta via Smad and p38Mapk up-regulates expression of actin-binding proteins including high-molecular-weight tropomyosins, alpha-actinin and calponin h2. We demonstrate that, among these proteins, tropomyosins are both necessary and sufficient for TGF-beta induction of stress fibers. Silencing of tropomyosins with short interfering RNAs (siRNAs) blocks stress fiber assembly, whereas ectopic expression of tropomyosins results in stress fibers. Ectopic-expression and siRNA experiments show that Smads mediate induction of tropomyosins and stress fibers. Interestingly, TGF-beta induction of stress fibers was not accompanied by changes in the levels of cofilin phosphorylation. TGF-beta induction of tropomyosins and stress fibers are significantly inhibited by Ras-ERK signaling in metastatic breast cancer cells. Inhibition of the Ras-ERK pathway restores TGF-beta induction of tropomyosins and stress fibers and thereby reduces cell motility. These results suggest that induction of tropomyosins and stress fibers play an essential role in TGF-beta control of cell motility, and the loss of this TGF-beta response is a critical step in the acquisition of metastatic phenotype by tumor cells

    The origin of a jury in ancient Greece and England

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    © 2016 Tumanov et al.The purpose of the study is to analyze the implementation of the democratic principles in the court and judicial process in the trial by jury by the example of the history and development of this institution in Russia. The authors used different methods and approaches, in particular, historical, systemic and Aristotelian method, concrete historical approach and rather-legal analysis. The paper assessed significance of the historical experience related to the organization and activities of the jury as a guarantor of successful implementation of democratic principles in the criminal trial, with regard to the international experience. The authors conclude that jury trial has its ancient roots, however, this modern phenomenon is taken from England. The research findings may be useful for future explorations on the origin of a jury by historians, philosophers and lawyers etc

    Characterisation of indeterminate focal breast lesions on grey-scale ultrasound: role of ultrasound elastography.

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    PURPOSE: This study was undertaken to evaluate the role of ultrasound (US) elastography in characterising focal breast lesions classified as indeterminate on B-mode US. MATERIALS AND METHODS: Eighty-four focal breast lesions, 64 benign and 20 malignant (mean diameter, 15.1 mm), detected but not characterised on B-mode US in 72 women, Breast Imaging Reporting and Data System (BI-RADS) US category 3 (n=56) or category 4 (n=28), were studied with US elastography and classified in consensus by two radiologists according to a five-point colour scale. Sensitivity, specificity and positive and negative predictive values (PPV and NPV) of US elastography compared with conventional US were calculated in relation to microhistology (n=67) and cytology (n=17), which were used as the reference standard. RESULTS: A total of 65/84 (77.4%) lesions were correctly classified as benign or malignant using US elastography, whereas the remaining 19/84 (22.6%) were incorrectly assessed. There were no statistically significant differences between US elastography and B-mode US with regard to sensitivity (70% vs. 68.4%), specificity (79.6% vs. 78.5%), PPV (51.8% vs. 48.1%) and NPV 89% vs. 89.5% (p>0.5). By contrast, a statistically significant difference was noted in the evaluation of BI-RADS 3 lesions, in which US elastography had 50% sensitivity, 86% specificity, 30% PPV and 93.5% NPV compared with BI-RADS 4 lesions (78.6%, 57.1%, 64.7% and 72.7%) (p<0.5). CONCLUSIONS: The high NPV of US elastography may help reduce the use of biopsy in BI-RADS 3 lesions, but its low PPV in BI-RADS 4 lesions does not allow avoidance of biopsy on the basis of the US elastographic score alone in this group of lesions

    Dietary studies in birds: testing a non-invasive method using digital photography in seabirds

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    This is the author accepted manuscript. The final version is available from the publisher via the DOI in this record.Dietary studies give vital insights into foraging behaviour, with implications for understanding changing environmental conditions and the anthropogenic impacts on natural resources. Traditional diet sampling methods may be invasive or subject to biases, so developing non-invasive and unbiased methods applicable to a diversity of species is essential. We used digital photography to investigate the diet fed to chicks of a prey-carrying seabird and compared our approach (photo-sampling) to a traditional method (regurgitations) for the greater crested tern Thalasseus bergii. Over three breeding seasons, we identified >24 000 prey items of at least 48 different species, more than doubling the known diversity of prey taken by this population of terns. We present a method to estimate the length of the main prey species (anchovy Engraulis encrasicolus) from photographs, with an accuracy <1 mm and precision ~ 0·5 mm. Compared to regurgitations at two colonies, photo-sampling produced similar estimates of prey composition and size, at a faster species accumulation rate. The prey compositions collected by two researchers photo-sampling concurrently were also similar. Photo-sampling offers a non-invasive tool to accurately and efficiently investigate the diet composition and prey size of prey-carrying birds. It reduces biases associated with observer-based studies and is simple to use. This methodology provides a novel tool to aid conservation and management decision-making in the light of the growing need to assess environmental and anthropogenic change in natural ecosystems.Department of Science and Technology, South Afric

    Chemical solution deposition of BiFeO3 films with layer-by-layer control of the coverage and composition

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    Chemical solution deposition of BiFeO3 thin films is one of the most commercially available techniques to produce large-scale low-cost coatings for further application in memory devices. In this contribution, we implemented piezoresponse force and conductive atomic force microscopies to study the layer-by-layer sol-gel deposition of BiFeO3 thin films focusing on the local phase distribution, morphology, piezoelectric response, and leakage current. The final properties of resulting thin films are found to be determined not only by the composition of the gel and crystallization step but by the gelation step as well. The drying temperature and treatment duration of the solution are shown to drastically influence the film coverage, which finally determines the morphology of the films and behavior of the crystallization process. © 2020 by the authors.Russian Science Foundation, RSF: 19-72-10076The research was funded by Russian Science Foundation, grant number 19-72-10076. The equipment of the Ural Center for Shared Use “Modern nanotechnology” UrFU was used
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