68 research outputs found

    Temperament and character dimensions, marital adjustment, and sexual satisfaction in couples with sexual dysfunction

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    Object: The objective of the study is to investigate the differences in temperament and character dimensions, marital adjustment and sexual satisfaction between the couples with and without sexual dysfunction (SD). Methods: The study group consists of 78 married women and 23 married men with SD diagnosis according to DSM-IV-TR diagnostic criteria and also their spouses (n=202). The comparison group is composed of married couples without SD (n=200). The participants were applied Personal Information Form, Temperament and Character Inventory (TCI), Golombok-Rust Inventory of Sexual Satisfaction (GRISS), Dyadic Adjustment Scale (DAS). Results: The couples with SD were observed to have higher cooperativeness and self-transcendence and lower self-directedness scores than those of the comparison group. The women partners in the couples with SD were found to take higher harm avoidance and lower self-directedness scores than the women in comparison group. Dyadic satisfaction, affectional expression and DAS total scores in the couples with SD were seen to be significantly less than those of the couples in the comparison group. It was found out that the women in the couples with SD took significantly higher scores in GRISS total score and all subscales, and men in the couples with SD took significantly higher scores in GRISS total score and subscales of satisfaction, avoidance, premature ejaculation and impotence than those in the comparison group. Discussion: It can be said that cyclothymic character, harm avoidance and self-directedness were the risk factors for SD. Marital adjustment and sexual satisfaction are insufficient in the couples with SD

    Vagal Nerve Schwannoma Clinically Mimicking Gastrointestinal Stromal Tumor: Report of a Case

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    Introduction: Mesenchymal tumors of the gastrointestinal (GI) tract are mainly comprised of a spectrum of spindle cell tumors which include gastrointestinal stromal tumors (GISTs), leiomyomas or leiomyosarcomas, and schwannomas. As all of these tumors of the GI are located in the submucosal layer of the bowell wall, differential diagnosis is very difficult. Histopathological evaluation using immunohistochemical staining is required for the definitive diagnosis.Presentation of case: A 20-year-old female patient was presented with an upper abdominal pain and dyspepsia since 2 months duration.This case  is initially thought as GIST but finally diagnosed as vagal nerve schwannoma by histopathological evaluation after resection of the mass.Conclusion: Schwannomas should be considered in the differential diagnosis of other mesenchimal tumors, such as gastrointestinal stromal tumors and leiomyomas or leiomyosarcomas, indeed it can grow in any part of the peripheral nerves along the gastrointestinal tract. Histopathological evaluation including immunohistochemical staining is required for the definitive diagnosis

    Učinak eksrakta kore brucijskog bora (Pinus brutia) na čiste i mješovite kulture buražnih bakterija i arheja te na fermentacijske značajke buraga in vitro

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    The aim of the study was to investigate the effects of Pinus brutia bark extract, which is rich in polyphenolic compounds of tannins, on both pure and mixed continuous cultures of rumen bacteria and archaea, as well as on rumen fermentation characteristics in vitro. Antimicrobial susceptibility assay with pure cultures was carried out in an anaerobic chamber. Pinus brutia bark extract exhibited a potential inhibitor activity (P<0.05) against pure cultures of Ruminococcus flavefaciens, Eubacterium ruminantium, and Methanobacterium formicicum while a growth stimulatory effect (P<0.05) was observed for Ruminoccocus albus, Butyrivibrio fibrisolvens, and Streptococcus bovis. Pinus brutia bark extract only had a potential inhibitor effect (P<0.05) on R. albus at the highest dose (1200 μg/mL). Pinus brutia bark extract also stimulated (P<0.05) the growth of pure cultures of Fibrobacter succinogenes, while it did not affect Megasphaera elsdenii, except at the highest dose. The effects of two doses (75 and 375 mg/L) of P. brutia bark extract on in vitro mixed cultures and rumen fermentation parameters were determined by the rumen simulation technique (Rusitec). Supplementation with P. brutia bark extract led to a quadratic decrease (P<0.05) in the cell numbers of R. flavefaciens. Production of total and individual short chain fatty acids (SCFA), acetate to propionate ratio (C2/C3), total protozoa, ruminal pH, and dry matter digestibility (DMD) did not change in the presence of P. brutia bark extract. Supplementation with both doses of P. brutia bark extract decreased (P<0.05) the ammonia-N concentrations. Ammonia-N concentration was lowest in the high-supplemented group (P<0.05). As a conclusion, inhibitory effects of P. brutia bark extract on some species in the pure cultures were in the same direction as with mixed ruminal cultures, while stimulatory effects disappeared. The lack of inhibitory effects on protozoa and on a large number of Gram-positive rumen bacteria in the mixed cultures suggests that its mechanism of action is not exactly similar to antibiotics. Although P. brutia bark extract did not alter ruminal SCFA, it could have potential to improve ruminal protein utilization without depressing rumen microbial fermentation.Cilj ovog rada bio je istražiti učinak ekstrakta kore brucijskog bora (Pinus brutia), koji je bogat polifenolnim sastojcima tanina, na čiste i mješovite kulture buražnih bakterija i arheja kao i na in vitro fermentacijske značajke buraga. Proveden je test antimikrobne osjetljivosti s čistim kulturama u anaerobnim uvjetima. Ekstrakt kore brucijskog bora pokazao je potencijalnu inhibitornu aktivnost (P < 0,05) protiv čistih kultura bakterija Ruminococcus flavefaciens, Eubacterium ruminantium i Methanobacterium formicicum, a stimulacijski učinak na rast (P < 0,05) opažen je za bakterije Ruminoccocus albus, Butyrivibrio fibrisolvens i Streptococcus bovis. Ekstrakt kore brucijskog bora imao je potencijalan inhibitorni učinak (P < 0,05) na R. albus samo u najvećoj dozi (1200 μg/mL). Također je imao stimulacijski učinak (P < 0,05) na čiste kulture Fibrobacter succinogenes, a nije utjecao na Megasphaera elsdenii osim u najvećoj dozi. Učinak dviju doza (75 i 375 mg/L) ekstrakta kore brucijskog bora na in vitro mješovite culture i pokazatelje fermentacije u buragu određen je simulacijskom tehnikom (Rusitec). Dodatak ekstrakta kore brucijskog bora doveo je do kvadratnog smanjenja (P < 0,05) broja stanica R. flavefaciens. Nije bilo promjena u proizvodnji ukupnih i pojedinačnih kratkolančanih masnih kiselina (SCFA), omjeru acetata i propionata (C2/C3), ukupnom broju protozoa, buražnom pH i probavljivosti suhe tvari (DMD). Suplementacija objema dozama ekstrakta kore brucijskog bora smanjila je (P < 0,05) koncentracije amonijaka-N. Koncentracija amonijaka-N bila je najniža u skupini s najvećom dozom suplementa (P < 0,05). Zaključujemo da je inhibitorni učinak ekstrakta kore brucijskog bora na neke vrste u čistim kulturama bio jednak onomu u mješovitim buražnim kulturama, a nije bilo stimulacijskog efekta. Manjak inhibitornih učinaka na protozoe i na mnoge Gram-pozitivne buražne bakterije u mješovitim kulturama upućuje na to da njihov mehanizam djelovanja nije jednak onomu kod antibiotika. Premda ekstrakt kore brucijskog bora nije promijenio buražni SCFA, mogao bi poboljšati iskorištavanje proteina u buragu a da pritom ne suprimira mikrobnu fermentaciju

    Concentrations of Connective Tissue Growth Factor in Patients with Nonalcoholic Fatty Liver Disease: Association with Liver Fibrosis

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    Aim: In this study, we aimed to investigate the relationship between the histological fibrosis stage of nonalcoholic fatty liver disease (NAFLD) and serum connective tissue growth factor (CTGF) to determine the usefulness of this relationship in clinical practice. Methods: Serum samples were collected from 51 patients with biopsy-proven NAFLD and 28 healthy controls, and serum levels of CTGF were assayed by ELISA. Results: Levels of CTGF were significantly higher in patients with NAFLD compared with controls (P = 0.001). The serum CTGF levels were significantly increased, that correlated with histological fibrosis stage, in patients with NAFLD [in patients with no fibrosis (stage 0) 308.2 ± 142.9, with mild fibrosis (stage 1–2) 519.9±375.2 and with advanced fibrosis (stage 3–4) 1353.2 ± 610 ng/l, P < 0.001]. Also serum level of CTGF was found as an independent predictor of histological fibrosis stage in patients with NAFLD (β = 0.662, t = 5.6, P < 0.001). The area under the ROC curve was estimated 0.931 to separate patients with severe fibrosis from patients with other fibrotic stages. Conclusion: Serum levels of CTGF may be a clinical utility for distinguishing NAFLD patients with and without advanced fibrosis

    Effect of Cognitive Behavioral Therapy on Sexual Satisfaction, Marital Adjustment, and Levels of Depression and Anxiety Symptoms in Couples with Vaginismus

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    WOS: 000411778500005PubMed ID: 28936816Objective: The aim of this study was to assess the effect of Cognitive Behavioral Therapy (CBT) on sexual functions of women with vaginismus and their husbands, their marital adjustment, and their levels of depression and anxiety symptoms. Method: Twenty-six couples diagnosed as vaginismus according to DSM-IV-TR diagnostic criteria in gynecology outpatient clinics of Izmir Ege Maternity Hospital and Gynecological Diseases Training and Research Hospital were included in the study. The couples were treated with CBT through 50-minute sessions once a week. Pre- and post-treatment, all couples were assessed using a Personal Information Form, Golombok-Rust Inventory of Sexual Satisfaction, Dyadic Adjustment Scale, Beck Depression Inventory, and Beck Anxiety Inventory. Results: There were significant differences in the total and all subscales' scores of sexual functions, significant increase in the marital adjustment, and a significant decrease in anxiety and depression symptom levels after CBT in women who completed the therapy (n = 20). In the husbands, significant recoveries were observed after the therapy in sexual functions total scores and subscales of satisfaction, avoidance, and impotence. However, there was no change in frequency, communication, sensuality, and in the premature ejaculation domains. Also, the marital adjustment scores increased, and significant decreases were observed in depression and anxiety symptom levels. Conclusion: It was observed that CBT is an appropriate therapy approach for vaginismus, and beneficial effects were observed in both women and their husbands in sexual functions, marital adjustment, and levels of depression and anxiety symptoms decreased

    Outcomes of Endoscopic Totally Extraperitoneal (TEP) repair of clinically occult inguinal hernia diagnosed with ultrasonography

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    Inguinal hernias generally present with groin lump and pain. Although inguinal hernias can be diagnosed clinically in most cases, patients without a groin lump pose a considerable diagnostic challenge. The first-line diagnostic imaging tool in these cases is ultrasound (US) and the recommended surgical procedure is laparoscopic-endoscopic repair. This retrospective study aims at evaluating postoperative results and complication rates of TEP technique in patients with occult contralateral hernias diagnosed with US in comparison to patients with clinically diagnosed hernias. A retrospective study was conducted to evaluate the outcomes of TEP procedure in patients with radiologically diagnosed occult contralateral hernias in comparison to patients with clinically diagnosed hernias. All hernias included in this study were repaired by TEP technique and secured with an extraperitoneal mesh. Demographic data, patient characteristics and perioperative information were obtained by reviewing medical records. A total number of 109 patients were enrolled in the study. The majority of patients were male and the mean age was 48.9 ± 14.6 years. In 56 cases, hernias were repaired unilaterally, while the remaining 53 were repaired bilaterally. Right-sided hernias were more common than left-sided hernias. The morbidity rate was 7.1% in unilateral repairs and 3.8% in bilateral repairs. The recurrence rate was 3.6% for unilateral repairs and 5.7% for bilateral repair. Some studies report that the incidence of clinical contralateral inguinal hernias identified after primary unilateral surgery is approximately 10%. If these contralateral hernias were diagnosed prior to the primary surgery, the risk of performing another operation could be avoided. Laparoscopic surgery enables bilateral hernia repair without any additional incisions, presenting similar morbidity rates when compared to unilateral repair. There was no significant difference between unilateral and bilateral TEP repair in terms of intraoperative and postoperative surgical complications. These results suggest that laparoscopic inguinal hernia repair is a safe and effective surgical technique for both unilateral and bilateral procedures. In order to prevent second operation, all patients with suspected inguinal hernia should undergo an US examination before surgery

    Are Personality Traits Effective in Marital Adjustment in Couples with Sexual Dysfunction? The Mediating Effect of Sexual Satisfaction

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    GOKDAG, CEREN/0000-0002-9111-2811WOS:000616944700006Objective: The primary aim of the study is to investigate the relationships between personality traits, marital relationship and sexual satisfaction in couples with sexual dysfunction (SD). The secondary aim is to examine the mediating effects of marital adjustment between personality traits and sexual satisfaction, and of sexual satisfaction between personality traits and marital adjustment. Method: The study was conducted with a total of 202 participants consisting of 101 married individuals diagnosed with SD and their spouses. Personal Information Form, Temperament and Character Inventory (TCI), Golombok-Rust Sexual Satisfaction Scale (GRISS), and Dyadic Adjustment Scale (DAS) were administered to the participants. Results: High harm avoidance and low self-directedness were associated with decreased marital adjustment and reduced sexual satisfaction. Reduced sexual satisfaction was related to the decreased marital adjustment. According to the results of multiple mediating analyzes, mediating effect of marital adjustment was not significant in the relationship between personality traits and sexual satisfaction, while the mediating effect of sexual satisfaction was significant in the relationship between personality traits and marital adjustment. Namely, self-directedness predicted the marital adjustment through the mediating role of sexual satisfaction. Conclusion: The results of this study demonstrated that the effects of personality traits on sexual satisfaction and marital adjustment should be considered cautiously and in detail, especially in people with SD. Interventions designed to improve healthy marital functioning should include personality traits and sexual satisfaction. in the psychotherapy for SD, focusing on personality traits and sexual functions can affect marital adjustment
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