Talent Management and Maintaining Talented Human Resource: A Case Study in Kashan University of Medical Sciences

This paper intends to survey the role of talent management in supply and maintaining talented human resource in Kashan University of Medical Science. The statistical population of research included senior managers, supervisors, assistants and heads of affiliated hospitals Medical Science University in Kashan. According to the few number of the statistical population, the census method is used and the number of samples is 63 persons. This study, in terms of the purpose, is a practical research and in terms of the method is a correlational type. The role of talent management on the talent pool, organization leaving, job stability and safety and avoiding key positions vacant were examined in this paper. According to the correlation analysis, the correlation coefficient of job stability and safety has the highest level with 0.426. The correlation coefficient of talent pool, organization leaving and avoiding key positions vacant was 0.193, -0.325, and 0.319, respectively

Talent Management and Maintaining Talented Human Resource: A Case Study in Kashan University of Medical Sciences

This paper intends to survey the role of talent management in supply and maintaining talented human resource in Kashan University of Medical Science. The statistical population of research included senior managers, supervisors, assistants and heads of affiliated hospitals Medical Science University in Kashan. According to the few number of the statistical population, the census method is used and the number of samples is 63 persons. This study, in terms of the purpose, is a practical research and in terms of the method is a correlational type. The role of talent management on the talent pool, organization leaving, job stability and safety and avoiding key positions vacant were examined in this paper. According to the correlation analysis, the correlation coefficient of job stability and safety has the highest level with 0.426. The correlation coefficient of talent pool, organization leaving and avoiding key positions vacant was 0.193, -0.325, and 0.319, respectively

Talent Management and Maintaining Talented Human Resource: A Case Study in Kashan University of Medical Sciences

This paper intends to survey the role of talent management in supply and maintaining talented human resource in Kashan University of Medical Science. The statistical population of research included senior managers, supervisors, assistants and heads of affiliated hospitals Medical Science University in Kashan. According to the few number of the statistical population, the census method is used and the number of samples is 63 persons. This study, in terms of the purpose, is a practical research and in terms of the method is a correlational type. The role of talent management on the talent pool, organization leaving, job stability and safety and avoiding key positions vacant were examined in this paper. According to the correlation analysis, the correlation coefficient of job stability and safety has the highest level with 0.426. The correlation coefficient of talent pool, organization leaving and avoiding key positions vacant was 0.193, -0.325, and 0.319, respectively

The protective effect of vitamin E on rats’ ovarian follicles following an administration of diazinon: An experimental study

Background: Diazinon (DZN) is an organophosphate insecticide that has been widely utilized in agriculture all over the world and caused many negative effects on different species such as plants and animal species, especially on a human. Objective: The aim of the present study was to evaluate the protective effect of vitamin E on rats’ ovarian follicles following an administration of diazinon. Materials and Methods: A total of 30 adult female Wistar rats were divided into five groups: a control group (without any intervention), sham group (received only pure olive oil, as solvent), experimental group I (DZN+olive oil, 60 mg/kg), experimental group II (vitamin E, 200 mg/kg), and experimental group III (DZN: 60 mg/kg+vitamin E: 200 mg/kg). All drugs were injected intraperitoneally, except vitamin E which was administrated by gavage. The animals were sacrificed after two weeks and the left ovary was used to measure proliferation of ovarian follicles. Tissues were analyzed by the PCNA technique and viewed with an optical microscope for evaluating cell proliferation. Results: The result of the present study revealed that the number of proliferative cells in the experimental group I decreased significantly in contrast to the control group in secondary and Graffian follicles (p< 0.001). The administration of vitamin E plus DZN significantly increased proliferative cells compared to the DZN group (p< 0.001). Primordial follicles showed that all study groups were lacking PCNA positive cells, which means no expression of PCNA in these follicles. The results of this study showed that primary follicles in all study groups had a few and scattered PCNA positive cells with no significant difference between the groups (p> 0.05). Conclusion: Results showed that DZN reduced proliferation in secondary and Graffian follicles and vitamin E increased it. The results of this study suggested that vitamin E by its antioxidant activity was able to improve the DZN-induced ovarian toxicity. Key words: Diazinon, Proliferation, Ovary, Vitamin E, Rat

Combined use of platelet-rich plasma and adipose tissue-derived mesenchymal stem cells shows a synergistic effect in experimental spinal cord injury

Spinal cord injury (SCI) as a crippling disability causes tissue degeneration via neuron loss and fiber disruption. Some researchers have tried to reverse or minimize these changes. Platelet-rich plasma (PRP) is a biological product derived from peripheral blood containing a variety of growth factors. PRP has been extensively used in regenerative medicine. On the other hand, via secreting neuroprotective growth factors, mesenchymal stem cells (MSCs) have shown a promising potential in repairing central nervous system deficits. This study investigated the therapeutic effect of the combined use of MSCs and PRP in a rat model of SCI. We used real time-PCR method for evaluation of Bcl-2, Bax and caspase 3 expressions, TUNEL test for apoptotic cell death assessment, and neurofilament NF200 immunohistochemistry for examination of axonal regeneration. The results showed that co-treatment with MSCs and PRP efficiently alleviated the evaluated categories. Significant differences were observed in expression of Bcl-2 and caspase3, but not Bax, apoptotic index and the number of NF200 positive axons (for all P </= 0.01) between co-treatment animals compared with those treated with only MSCs or PRP. In conclusion, this study showed that combination of MSCs and PRP synergistically promotes their therapeutic effects in the SCI

Effect of Facilitated Tucking with the Nurse and a Simulated Hand on Physiological Pain Index During Vein Puncture on Premature Infants

BACKGROUND AND OBJECTIVE: Painful and stressful stimuli increase catecholamine, heart rate, blood pressure and increase the intracranial pressure of the baby. Facilitated tucking is a simple technique that makes the baby control her body better. Therefore, this study was performed to compare the effects of fetal status with hands of nurses and simulated hand on the physiological indices of pain during venipuncture in preterm infants. METHODS: The present experimental study was performed on 99 preterm infants admitted to the intensive care unit of Amin and Shahid Beheshti hospitals of Isfahan and in three groups of 33 patients (two groups of test and one control group). In one of the test groups during venipuncture procedure neonates were placed in facilitated tucking by nurse’s hand and in the other group by simulated hands. Before, during and after the intravenous route, the respiratory rate, pulse rate and arterial oxygen saturation were recorded using monitors. FINDINGS: The mean of arterial oxygen saturation during and after venipuncture in the nurses' hand group were (93.04±6.13) and (94.3±56.44) and in simulated hand group were (95.2±21.11) and (94.2±50.86%) which had no significant difference (p<0.05). Between the mean respiratory rate, during and after the venipuncture in the nurses' hand (49.9±85.88) and (54.11±03.85) with simulated hand group (50.64±11.48) and (57.10±96.82) was not significantly different. CONCLUSION: The results of the study showed that the use of nursing hands and simulated hands to put a premature infant in a facilitated tucking is effective equally in controlling the physiological indices

A Review on Potential Mechanisms of Terminalia chebula

The current management of Alzheimer’s disease (AD) focuses on acetylcholinesterase inhibitors (AChEIs) and NMDA receptor antagonists, although outcomes are not completely favorable. Hence, novel agents found in herbal plants are gaining attention as possible therapeutic alternatives. The Terminalia chebula (Family: Combretaceae) is a medicinal plant with a wide spectrum of medicinal properties and is reported to contain various biochemicals such as hydrolysable tannins, phenolic compounds, and flavonoids, so it may prove to be a good therapeutic alternative. In this research, we reviewed published scientific literature found in various databases: PubMed, Science Direct, Scopus, Web of Science, Scirus, and Google Scholar, with the keywords: T. chebula, AD, neuroprotection, medicinal plant, antioxidant, ellagitannin, gallotannin, gallic acid, chebulagic acid, and chebulinic acid. This review shows that T. chebula extracts and its constituents have AChEI and antioxidant and anti-inflammatory effects, all of which are currently relevant to the treatment of Alzheimer’s disease

Protective effects of peel and seed extracts of Citrus aurantium on glutamate-induced cytotoxicity in PC12 cell line

A b s t r a c t Oxidative stress and apoptosis contribute to neuronal degeneration in many neurodegenerative diseases such as Alzheimer&apos;s disease. Glutamate is a major excitatory neurotransmitter in the central nervous system (CNS) and is considered responsible for the pathogenesis of many neurological disorders. Reactive oxygen species (ROS) production is thought to be involved in glutamate-induced apoptosis process. In this study, the neuroprotective effects of Citrus aurantium in the glutamate-induced rat&apos;s adrenal pheochromocytoma cell line (PC12 cells) were investigated. The cell viability and apoptotic cell death were measured using MTT and propidium iodine (PI)

Antioxidant and toxicity studies of biosynthesized cerium oxide nanoparticles in rats

Funding Information: We would like to thank the Vice Chancellery for Research and Technology, MUMS for financial support (grant no 930954) and facilities.Peer reviewedPublisher PD

Cuscuta campestris induces apoptosis by increasing reactive oxygen species generation in human leukemic cells

Objective: Cuscuta campestris or common dodder is a holoparasitic  plant  that  has  been valorized for treatment of liver injury and cancer prevention in traditional medicine. Recently, extract of C. campestris had shown moderate antimicrobial properties and cytotoxic effects. In this study, we examined the level of cellular oxidants, cytotoxicity, apoptosis and differentiation induced by hydroalcoholic extract of C. campestris(CCE)(12.5-200 µg/ml), as well as arsenic trioxide (As2O3, 50 µM), in human leukemic (HL60 and NB4) and normal polymorph nuclear cells after 72 hr treatment. Materials and Methods: Resazurin assay was used to determine cell viability following treatment with C. campestris. Intracellular reactive oxygen species (ROS) and apoptotic cells were measured by fluorimetry using carboxy 2′, 7′-dichlorofluorescein diacetate and propidium iodide (PI), as staining reagents, respectively. The differentiation of leukemic cells was evaluated by Giemsa staining and nitro blue tetrazolium (NBT) reduction. Results: C. campestris inhibited cell viability with IC50 values of 23.9 µg/ml for HL60 and 60.3 µg/ml for NB4 cells after 72 hr treatment. ROS formation was also concentration-dependently increased following treatment with C. campestris. In addition, the number of apoptotic cells significantly increased to 88.4% and 62.3% in CCE (200 µg/ml)-treated HL60 and NB4 cells, respectively, which was higher than that of As2O3 (50 µM)-treated leukemic cells (