Evaluation of appendicitis risk prediction models in adults with suspected appendicitis

Background Appendicitis is the most common general surgical emergency worldwide, but its diagnosis remains challenging. The aim of this study was to determine whether existing risk prediction models can reliably identify patients presenting to hospital in the UK with acute right iliac fossa (RIF) pain who are at low risk of appendicitis. Methods A systematic search was completed to identify all existing appendicitis risk prediction models. Models were validated using UK data from an international prospective cohort study that captured consecutive patients aged 16–45 years presenting to hospital with acute RIF in March to June 2017. The main outcome was best achievable model specificity (proportion of patients who did not have appendicitis correctly classified as low risk) whilst maintaining a failure rate below 5 per cent (proportion of patients identified as low risk who actually had appendicitis). Results Some 5345 patients across 154 UK hospitals were identified, of which two‐thirds (3613 of 5345, 67·6 per cent) were women. Women were more than twice as likely to undergo surgery with removal of a histologically normal appendix (272 of 964, 28·2 per cent) than men (120 of 993, 12·1 per cent) (relative risk 2·33, 95 per cent c.i. 1·92 to 2·84; P < 0·001). Of 15 validated risk prediction models, the Adult Appendicitis Score performed best (cut‐off score 8 or less, specificity 63·1 per cent, failure rate 3·7 per cent). The Appendicitis Inflammatory Response Score performed best for men (cut‐off score 2 or less, specificity 24·7 per cent, failure rate 2·4 per cent). Conclusion Women in the UK had a disproportionate risk of admission without surgical intervention and had high rates of normal appendicectomy. Risk prediction models to support shared decision‐making by identifying adults in the UK at low risk of appendicitis were identified

Investigaciones de estudiantes

In this last chapter, 5 investigations carried out by students are listed of the Faculty of Architecture of the University of Palermo. These jobs were tutored by teachers and are part of the learning process developed through through research in classrooms and workshops. The authors of the works listed are: Martin Alday, Leandro Palacios, Catriel Trasmonte, Julieta Lema, Candela Belén Robles and Facundo Sacks, Agustina Prieto and Paula SapagEn este último capítulo se listan 5 investigaciones desarrolladas por alumnos de la Facultad de Arquitectura de la Universidad de Palermo. Estos trabajos fueron tutoriados por profesores y forman parte del proceso de aprendizaje desarrollado a través de la investigación en las aulas y talleres. Los autores de los trabajos listados son: Martin Alday, Leandro Palacios, Catriel Trasmonte, Julieta Lema, Candela Belén Robles y Facundo Sacks, Agustina Prieto y Paula SapagNeste último capítulo, são listadas 5 investigações realizadas pelos alunos da Faculdade de Arquitetura da Universidade de Palermo. Essas obras foram supervisionadas pelos professores e fazem parte do processo de aprendizagem desenvolvido de pesquisa em salas de aula e oficinas. Os autores das obras listadas são: Martin Alday, Leandro Palacios, Catriel Trasmonte, Julieta Lema, Candela Belén Robles y Facundo Sacks, Agustina Prieto e Paula Sapag