Y-chromosome SNP haplotypes suggest evidence of gene flow among caste, tribe, and the migrant Siddi populations of Andhra Pradesh, South India

From observations of lack of haplotype sharing based on Y-chromosome specific short tandem repeat (STR) loci, previous reports suggested negligible gene flow among different geographic populations of India. Using Single Nucleotide Polymorphism (SNP) sites in combination with STRs, we observed evidence of haplotype sharing across caste-tribe boundaries in South India. We examined 27 SNPs in the non-recombining region of the Y chromosome to investigate gene flow in 204 individuals belonging to three caste groups (Vizag Brahmins, Peruru Brahmins, Kammas), three tribes (Bagata, Poroja, Valmiki) and an additional group (the Siddis) of African ancestry. Principal component and AMOVA analyses show that the between group component of variation is non-significant (P>0.05), while that among populations within the caste and tribal groups is significant (P<0.001). In particular, the Valmikis and Siddis are close to the caste groups. Of a total of 11 distinct SNP-haplotypes observed, the two tribal groups (Bagata and Poroja) lack the haplotypes H4, H4A, H5A and H16, which are seen in the caste groups. In contrast, all three tribal groups exhibit the Southeast Asian haplotype H11 that is absent in the caste populations. The presence of haplotypes H4, H5, H14, and H16 in the Siddis indicate that they have assimilated considerable non-African admixture. The evidence of haplotype sharing between castes and tribes is also found when the H14 lineage was further subdivided by five STR loci. We conclude that even though these SNP-based Y-haplotypes are able to distinguish the populations, gene flow in these South Indian populations is not as negligible as that inferred from other studies based on Y-specific short tandem repeat markers

1,4-Bis[(2-pyridylethyl)iminomethyl]- benzene

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Composite Fermion Description of Correlated Electrons in Quantum Dots: Low Zeeman Energy Limit

We study the applicability of composite fermion theory to electrons in two-dimensional parabolically-confined quantum dots in a strong perpendicular magnetic field in the limit of low Zeeman energy. The non-interacting composite fermion spectrum correctly specifies the primary features of this system. Additional features are relatively small, indicating that the residual interaction between the composite fermions is weak. \footnote{Published in Phys. Rev. B {\bf 52}, 2798 (1995).}Comment: 15 pages, 7 postscript figure

Plesionika quasigrandis Chace, 1985 (decapoda, caridea, pandalidae) from Southwestern India

The recent development of commercial deep-sea fisheries in India has mainly been off the southern coast and is based on shrimps (Rajan et al., 2001; Kurup et al., 2008; Rajool Shanis et al., 2014b). One of the dominant species in these catches is a pandalid shrimp previously reported as “Parapandalus (or Plesionika) spinipes” (e.g., Suseelan & Mohamed, 1968; Suseelan, 1974; Rajan et al., 2001; Kurup et al., 2008; Rajool Shanis et al., 2012; with the genus Parapandalus Borradaile, 1899 now generally synonymized with Plesionika Bate, 1888 (see Chace, 1985; De Grave & Fransen, 2011). Rajool Shanis et al. (2014a, b) later showed that this name was a misidentification of Plesionika quasigrandis Chace, 1985, which has the ventral rostral teeth more densely packed as opposed to P. spinipes, where the dorsal rostral teeth are more densely packed (see Chace, 1985; Chan & Crosnier, 1991). Although P. quasigrandis is one of the most important deep-sea shrimps in India from a commercial point of view, no proper taxonomic account has been given for the Indian material. The present study provides detailed taxonomic information of P. quasigrandis from India, together with molecular barcoding data

Resonant scattering of the OVII X-ray emission line in the circumgalactic medium of TNG50 galaxies

We study the impact of resonantly scattered X-ray line emission on the observability of the hot circumgalactic medium (CGM) of galaxies. We apply a Monte Carlo radiative transfer post-processing analysis to the high-resolution TNG50 cosmological magnetohydrodynamical galaxy formation simulation. This allows us to model the resonant scattering of OVII(r) X-ray photons within the complex, multi-phase, multi-scale CGM. The resonant transition of the OVII He-like triplet is one of the brightest, and most promising, X-ray emission lines for detecting the hot CGM and measuring its physical properties. We focus on galaxies with stellar masses 10 < log(M*/Msun) < 11 at z ~ 0. After constructing a model for OVII(r) emission from the central galaxy as well as from CGM gas, we forward model these intrinsic photons to derive observable surface brightness maps. We find that scattering significantly boosts the observable OVII(r) surface brightness of the extended and diffuse CGM. This enhancement can be large -- an order of magnitude on average at a distance of 200 projected kpc for high-mass M* = 10^10.7 Msun galaxies. The enhancement is larger for lower mass galaxies, and can even reach a factor of 100, across the extended CGM. Galaxies with higher star formation rates, AGN luminosities, and central OVII(r) luminosities all have larger scattering enhancements, at fixed stellar mass. Our results suggest that next-generation X-ray spectroscopic missions including XRISM, LEM, ATHENA, and HUBS -- which aim to detect the hot CGM in emission -- could specifically target halos with significant enhancements due to resonant scattering.Comment: Published in MNRAS. See https://www.lem-observatory.org/ and https://www.tng-project.org/ for more details; 2023MNRAS.522.3665

Evaluation of annealed titanium oxide nanotubes on titanium: From surface characterization to in vivo assays

The entire route from anodic oxidation and surface characterization, including in vitro experiments and finally in vivo osseointegration assays were performed with the aim to evaluate nanotubular and crystalline annealed titanium oxides as a suitable surface for grade 2 titanium permanent implants. Polished titanium (T0) was compared with anodized surfaces obtained in acidic media with fluoride, leading to an ordered nanotubular structure of titanium oxide on the metal surface, characterized by tube diameter of 89 ± 24 nm (Tnts). Samples were thermally treated in air (TntsTT) to increase the anatase crystalline phase on nanotubes, with minor alteration of the structure. Corrosion tests were performed to evaluate the electrochemical response after 1, 14, and 28 days of immersion in simulated body fluid. Based on the in vitro results, heat-treated titanium nanotubes (TntsTT) were selected as a promissory candidate to continue with the osseointegration in vivo assays. The in vivo results showed no major improvement in the osseointegration process when compared with untreated Ti after 30 days of implantation and there also was a lower increase in the development of new osseous tissue.Fil: Gomez Sanchez, Andrea Valeria. Universidad Tecnológica Nacional; ArgentinaFil: Katunar, María R.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; ArgentinaFil: Pastore, Juan Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones Científicas y Tecnológicas en Electrónica. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones Científicas y Tecnológicas en Electrónica; ArgentinaFil: Tano de la Hoz, María Florencia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; ArgentinaFil: Ceré, Silvia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; Argentin

Identification and functional characterization of muscle satellite cells in Drosophila

Work on genetic model systems such as Drosophila and mouse has shown that the fundamental mechanisms of myogenesis are remarkably similar in vertebrates and invertebrates. Strikingly, however, satellite cells, the adult muscle stem cells that are essential for the regeneration of damaged muscles in vertebrates, have not been reported in invertebrates. In this study, we show that lineal descendants of muscle stem cells are present in adult muscle of Drosophila as small, unfused cells observed at the surface and in close proximity to the mature muscle fibers. Normally quiescent, following muscle fiber injury, we show that these cells express Zfh1 and engage in Notch-Delta-dependent proliferative activity and generate lineal descendant populations, which fuse with the injured muscle fiber. In view of strikingly similar morphological and functional features, we consider these novel cells to be the Drosophila equivalent of vertebrate muscle satellite cells

Hamiltonian Theory of the FQHE: Conserving Approximation for Incompressible Fractions

A microscopic Hamiltonian theory of the FQHE developed by Shankar and the present author based on the fermionic Chern-Simons approach has recently been quite successful in calculating gaps and finite tempertature properties in Fractional Quantum Hall states. Initially proposed as a small-$q$ theory, it was subsequently extended by Shankar to form an algebraically consistent theory for all $q$ in the lowest Landau level. Such a theory is amenable to a conserving approximation in which the constraints have vanishing correlators and decouple from physical response functions. Properties of the incompressible fractions are explored in this conserving approximation, including the magnetoexciton dispersions and the evolution of the small-$q$ structure factor as \nu\to\half. Finally, a formalism capable of dealing with a nonuniform ground state charge density is developed and used to show how the correct fractional value of the quasiparticle charge emerges from the theory.Comment: 15 pages, 2 eps figure