13 research outputs found
Prognostic model to predict postoperative acute kidney injury in patients undergoing major gastrointestinal surgery based on a national prospective observational cohort study.
- Author
- Aamir A
- Abbas J
- Abbas N
- Abbott TEF
- Abdalla M
- Abdikadir H
- Abuhussein N
- Acquaah F
- Adamson R
- Adeleye O
- Adeogun A
- Adlan A
- Aftab R
- Afzal Z
- Agarwal M
- Aglan H
- Agnew CJF
- Agrawal R
- Ahern D
- Ahluwalia J
- Ahluwalia V
- Ahmad A
- Ahmad K
- Ahmed H
- Ahmed I
- Ahmed L
- Ahmed N
- Ahmed P
- Ainger E
- Ainsworth P
- Aishwarya G
- Ajibola-Taylor O
- Akhbari M
- Akhtar A
- Akhtar R
- Akpenyi O
- Al-Ausi M
- Al-Huneidi R
- Al-Khudairi R
- Al-Masri S
- Al-Mousawi A
- Al-Saadi N
- Alagappan A
- Alberts J
- Alfa-Wali M
- Ali A
- Ali B
- Ali I
- Ali M
- Ali Q
- Ali S
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- Alwandi A
- Amani L
- Amarnath T
- Amer M
- Amin H
- Amin MN
- Amoah R
- Amoah-Arko A
- Anandarajah C
- Ananthavarathan P
- Andah EJE
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- Appleton S
- Aquilina T
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- Arneill M
- Arnell S
- Arnold TJ
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- Ashwood J
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- Aubrey-Jones D
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- Auluck I
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- STARSurg Collaborative Writing Committee, Data analysis, Steering committee, Advisory group, Regional leads, Collaborators and validators
- STARSurg Collaborative Writing Committee, Data analysis, Steering committee, Advisory group, Regional leads, Collaborators and validators, Nepogodiev, D
- Stechman M
- Stewart D
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- Zubikarai G
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- Publication venue
- 'Wiley'
- Publication date
- 18/05/2018
- Field of study
Background: Acute illness, existing co-morbidities and surgical stress response can all contribute to postoperative acute kidney injury (AKI) in patients undergoing major gastrointestinal surgery. The aim of this study was prospectively to develop a pragmatic prognostic model to stratify patients according to risk of developing AKI after major gastrointestinal surgery. Methods: This prospective multicentre cohort study included consecutive adults undergoing elective or emergency gastrointestinal resection, liver resection or stoma reversal in 2-week blocks over a continuous 3-month period. The primary outcome was the rate of AKI within 7 days of surgery. Bootstrap stability was used to select clinically plausible risk factors into the model. Internal model validation was carried out by bootstrap validation. Results: A total of 4544 patients were included across 173 centres in the UK and Ireland. The overall rate of AKI was 14·2 per cent (646 of 4544) and the 30-day mortality rate was 1·8 per cent (84 of 4544). Stage 1 AKI was significantly associated with 30-day mortality (unadjusted odds ratio 7·61, 95 per cent c.i. 4·49 to 12·90; P < 0·001), with increasing odds of death with each AKI stage. Six variables were selected for inclusion in the prognostic model: age, sex, ASA grade, preoperative estimated glomerular filtration rate, planned open surgery and preoperative use of either an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker. Internal validation demonstrated good model discrimination (c-statistic 0·65). Discussion: Following major gastrointestinal surgery, AKI occurred in one in seven patients. This preoperative prognostic model identified patients at high risk of postoperative AKI. Validation in an independent data set is required to ensure generalizability
Intraperitoneal drain placement and outcomes after elective colorectal surgery: international matched, prospective, cohort study
- Author
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- Abdellatif M
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- van Dalen AS
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- Yang HW
- Yao L
- Yap SHK
- Yasin I
- Yates C
- Yates C
- Yek WY
- Yeo JY
- Yick C
- Yick C
- Yıldırım A
- Yogarajah T
- Yoldas T
- Yotsov T
- Yousaf H
- Yousuff M
- Yánez C
- Yüksel E
- Zabiyaka M
- Zafer F
- Zafer F
- Zaffaroni G
- Zagibová D
- Zagorac Z
- Zaheer M
- Zahid A
- Zahid M
- Zaidi M
- Zambon M
- Zammit-Maempel M
- Zanframundo C
- Zanni M
- Zayed M
- Zazza S
- Zeidan Z
- Zhang Y
- Zhu L
- Zhu X
- Ziolkowska K
- Ziolkowska K
- Zografos G
- Zonta S
- Çetin B
- Ölmez M
- Özbalcı GS
- Özen D
- Özen D
- Öztürk OU
- Čustović S
- Štefanová H
- Ευσταθίου Η
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2022
- Field of study
Despite current guidelines, intraperitoneal drain placement after elective colorectal surgery remains widespread. Drains were not associated with earlier detection of intraperitoneal collections, but were associated with prolonged hospital stay and increased risk of surgical-site infections.Background Many surgeons routinely place intraperitoneal drains after elective colorectal surgery. However, enhanced recovery after surgery guidelines recommend against their routine use owing to a lack of clear clinical benefit. This study aimed to describe international variation in intraperitoneal drain placement and the safety of this practice. Methods COMPASS (COMPlicAted intra-abdominal collectionS after colorectal Surgery) was a prospective, international, cohort study which enrolled consecutive adults undergoing elective colorectal surgery (February to March 2020). The primary outcome was the rate of intraperitoneal drain placement. Secondary outcomes included: rate and time to diagnosis of postoperative intraperitoneal collections; rate of surgical site infections (SSIs); time to discharge; and 30-day major postoperative complications (Clavien-Dindo grade at least III). After propensity score matching, multivariable logistic regression and Cox proportional hazards regression were used to estimate the independent association of the secondary outcomes with drain placement. Results Overall, 1805 patients from 22 countries were included (798 women, 44.2 per cent; median age 67.0 years). The drain insertion rate was 51.9 per cent (937 patients). After matching, drains were not associated with reduced rates (odds ratio (OR) 1.33, 95 per cent c.i. 0.79 to 2.23; P = 0.287) or earlier detection (hazard ratio (HR) 0.87, 0.33 to 2.31; P = 0.780) of collections. Although not associated with worse major postoperative complications (OR 1.09, 0.68 to 1.75; P = 0.709), drains were associated with delayed hospital discharge (HR 0.58, 0.52 to 0.66; P < 0.001) and an increased risk of SSIs (OR 2.47, 1.50 to 4.05; P < 0.001). Conclusion Intraperitoneal drain placement after elective colorectal surgery is not associated with earlier detection of postoperative collections, but prolongs hospital stay and increases SSI risk
An interview with David Normando
- Author
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Lung biodurability and free radical production of cellulose nanomaterials
- Author
- Agarwal UP
- Aleksandr B. Stefaniak
- Alexandrescu L
- Bai W
- Beck S
- Buettner GR
- Cullen RT
- Dahlgren C
- Donaldson K
- Donaldson K
- Fenoglio I
- Finch GL
- French AD
- Habibi Y
- Hubbe M
- Janzen EG
- Kanapilly GM
- Krusic PJ
- Lee KY
- Leonard SS
- Leonard SS
- Male KB
- Mansikkamaki P
- Martinez KF
- Mathew AP
- Mohindar S. Seehra
- Moon RJ
- Muhle H
- Natalie R. Fix
- Park S
- Pereira MM
- Qi WH
- Ruiz MM
- Saito T
- Seehra MS
- Segal L
- Sehaqui H
- Siqueira G
- Stefaniak AB
- Stephen S. Leonard
- Sun CQ
- Tatrai E
- Vallyathan V
- Vartiainen J
- Wittmaack K
- Zoppe JO
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Effect of Size Reduction on Magnetic Ordering in Sm1−x Ca x MnO3 (x = 0.35, 0.65 and 0.92) Manganites: Magnetic and EMR Studies
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Migration of mineral oil in elastomers
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
High-early-strength ductile cementitious composites with characteristics of low early-age shrinkage for repair of infrastructures
- Author
- A Bentur
- BSM Persson
- D Knofel
- D Whiting
- DP Bentz
- F Parker
- G Li
- G Mays
- Gürkan Yıldırım
- J Anderson
- JJ Brooks
- M Li
- M Şahmaran
- MH Zhang
- Mohamed Lachemi
- Muhannad Al-Emam
- Mustafa Şahmaran
- P Soroushian
- PK Mehta
- S Qian
- S Qian
- S Wang
- S Zhutovsky
- SL Mak
- SS Seehra
- Tahir Kemal Erdem
- VC Li
- VC Li
- VC Li
- VC Li
- W Narayan
- Y Yang
- Yunus Emre Şimşek
- Z Lin
- Z Lin
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Dynamic Magnetization Switching in NiO Nanoparticles: Pulsed Field Magnetometry Study
- Author
- A. A. Dubrovskiy
- A. A. Krasikov
- A. D. Balaev
- AD Balaev
- Ch Rani
- D. A. Balaev
- DA Balaev
- DA Balaev
- DA Balaev
- DA Balaev
- DA Balaev
- DA Balaev
- DA Balaev
- EC Stoner
- F Bødker
- H Shim
- IS Poperechny
- IS Poperechny
- K Dobretsov
- M Knobel
- M Tadic
- MS Seehra
- NJO Silva
- NJO Silva
- O. N. Martyanov
- QA Pankhurst
- RH Kodama
- S Mørup
- S. I. Popkov
- SA Makhlouf
- SA Makhlouf
- SA Makhlouf
- SD Chandni Rani
- SS Yakushkin
- TS Berquó
- V. L. Kirillov
- WC Nunes
- YuL Raikher
- YuP Kalmykov
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Transforming growth factor-β superfamily ligand trap ACE-536 corrects anemia by promoting late-stage erythropoiesis
- Author
- A Cao
- AC McPherron
- AL Lau
- Asya V Grinberg
- C Camaschella
- C Iancu-Rubin
- CC Rider
- CN Roy
- D Bowen
- D Sako
- Dianne Mitchell
- Dianne Sako
- E Jabbour
- FS Loffredo
- HB Lee
- HE Broxmeyer
- HH Wu
- IV Libani
- J Kim
- J Yu
- Jasbir Seehra
- John D Quisel
- K Chen
- Kathryn W Underwood
- Kenneth S Loveday
- L Zhou
- M Koulnis
- M Scharpfenecker
- M Shiozaki
- M Shiozaki
- M Socolovsky
- Mark J Alexander
- Matthew Devine
- ML Sherman
- Monique V Davies
- MP Menon
- R Scott Pearsall
- RA Ignotz
- Rajasekhar N V S Suragani
- Rajesh Chopra
- Ravindra Kumar
- RE Smith Jr.
- RF Paulson
- RN Suragani
- Robert Li
- S Akel
- S Eshghi
- SA Townson
- Samuel M Cadena
- Sharon M Cawley
- SM Cadena
- SM Hattangadi
- SS Söderberg
- T Tanno
- U Blank
- V Maguer-Satta
- Y Ginzburg
- Y Liu
- Y Shav-Tal
- YW Lin
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
3D microstructure of magnesium potassium phosphate ceramics from X-ray tomography: new insights into the reaction mechanisms
- Author
- A Covill
- A Navarre-Sitchler
- A Navrotsky
- A Taris
- A Viani
- A Viani
- A Viani
- A Viani
- A Viani
- A Viani
- A Viani
- A Wilson
- AD Wilson
- Alberto Viani
- B Mandelbrot
- B Xu
- B Xu
- BEI Abdelrazig
- C Moseke
- CK Chau
- D Paganin
- DA Hall
- DA Hall
- DN Winslow
- E Maire
- E Soudée
- EJY Ling
- F Abbona
- F Abbona
- F Brun
- F Brun
- F Brun
- F Brun
- F Qiao
- F Xing
- Gabriele Lanzafame
- H Lahalle
- H Ma
- HA Ibrahim
- HE Stanley
- HF Jelinek
- J Bear
- J Li
- J Schindelin
- J Weickert
- J Zhang
- Konstantinos Sotiriadis
- LM Anovitz
- Lucia Mancini
- M Pérez-Estébanez
- M Rouzic Le
- M Rouzic Le
- MS Costanza-Robinson
- N Ostrowski
- N Otsu
- P Cloetens
- P Mostaghimi
- P Pfeifer
- R Al-Raoush
- R Neiman
- R Wheeler
- SA Walling
- SS Seehra
- SW Wilkins
- WB Lindquist
- Y Li
- Y Li
- Z Ding
- Z Ding
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study