1,453 research outputs found

    #BLM Insurgent Discourse, White Structures of Feeling and the Fate of the 2020 "Racial Awakening"

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    Working with Twitter data, this paper offers new findings on the #BlackLivesMatter movement and "racial awakening" of summer 2020. Framing methods to address this important moment, this paper contends that cultural studies and critical race studies can be enriched through an engagement with new computational approaches. We analyze how white and racial minority voices talked about race and track their fraught contestation for leadership of racial discourse over the summer of 2020. We uncover a surprising story of white colorblindness even in the midst of a "racial awakening," a story that questions claims that the Trump presidency and the summer of 2020 ushered in a new era of US racial consciousness. And we show how a Black and minority discourse with transformative potential surged and receded. For cultural studies, our data and analysis revise Raymond Williams's influential model of cultural evolution by introducing a new concept: the insurgent, a long-building minority cultural strain that surges to contest the dominant culture in a moment of crisis. For critical race studies, our findings revise prominent theorizations of colorblindness, racial ideology, and hegemony. By revealing the messy and unconscious feelings characterizing colorblindness, our data contest theorizations of colorblindness as an ideology and counter the focus on articulate beliefs in theories of racial hegemony. Ultimately, this paper shows that bringing data methods focused on moments of cultural contestation and mass communication into dialogue with field-specific theory and qualitative analyses can expand our models of how race, discourse, and culture operate

    What patient-reported outcome measures may be suitable for research involving older adults with frailty? A scoping review

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    This is the final version. Available on open access from Springer via the DOI in this record. Data availability: Data are available in Appendices 2 and 3 in Supplementary material.INTRODUCTION: The need to develop and evaluate frailty-related interventions is increasingly important, and inclusion of patient-reported outcomes is vital. Patient-reported outcomes can be defined as measures of health, quality of life or functional status reported directly by patients with no clinician interpretation. Numerous validated questionnaires can thus be considered patient-reported outcome measures (PROMs). This review aimed to identify existing PROMs currently used in quantitative research that may be suitable for older people with frailty. METHOD: PubMed and Cochrane were searched up to 24/11/22. Inclusion criteria were quantitative studies, use of a PROM, and either measurement of frailty or inclusion of older adult participants. Criteria were created to distinguish PROMs from questionnaire-based clinical assessments. 197 papers were screened. PROMs were categorized according to the domain assessed, as derived from a published consensus 'Standard Set of Health Outcome Measures for Older People'. RESULTS: 88 studies were included. 112 unique PROMs were used 289 times, most frequently the SF-36 (n = 21), EQ-5D (n = 21) and Barthel Index (n = 14). The most frequently assessed outcome domains included Mood and Emotional Health and Activities of Daily Living, with fewer assessments of Participation in Decision-Making and Carer Burden. CONCLUSIONS: PROM usage in frailty research is highly heterogeneous. Frequently used PROMs omit important outcomes identified by older adults. Further research should evaluate the importance of specific outcomes and identify PROMs relevant to people at different stages of frailty. Consistent and appropriate PROM use in frailty research would facilitate more effective comparisons and meaningful evaluation of frailty interventions.Royal Devon & Exeter HospitalNational Institute for Health and Care Research (NIHR

    MMSE-Based MDL Method for Accurate Source Number Estimation

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    Economic developments in South Fukien, 946-1276

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    The region of South Fukien did not develop economically to any marked degree until the Sung dynasty. Its development during the Sung can be divided into three periods. The first period lasted from the rule of the independent local warlords to the last quarter of the eleventh century . During this one hundred years, agriculture underwent improvements which made substantial population growth and accumulation of capital possible . This generated a substantial momentum for development in commerce by local merchants, and a flourishing transit trade . The second period , which lasted to the end of the twelfth century , was a time of general prosperity in the region's economy. The overseas trade now became a mixture of transit and export trade and expanded to an unprecedented extent, and other economic sectors developed in response to this commercial boom. The third phase - the latter half of the Southern Sung - was a time when overseas trade declined markedly and problems appeared in the local economy. The region turned its commercial orientation from overseas to domestic trade and was not able to enjoy the balanced prosperity it had earlier

    A step into the world of Pakistanis: oral health education for Pakistani adults in Hong Kong

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    Includes bibliographical references (p. 32).Questionnaire in English and Urdu.published_or_final_versio

    Formal Subdivision of the Holocene Series/Epoch: A Summary

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    The Holocene Series/Epoch is the most recent series/epoch in the geological timescale, spanning the interval from 11,700 yr to the present day. Together with the subadjacent Pleistocene, it comprises the Quaternary System/Period. The Holocene record contains diverse geomorphological, biotic, climatological and archaeological evidence, within sequences that are often continuous and extremely well-preserved at decadal, annual and even seasonal resolution. As a consequence, the Holocene is perhaps the most intensively-studied series/epoch within the entire Geological Time Scale. Yet until recently little attention had been paid to a formal subdivision of the Holocene. Here we describe an initiative by the Subcommission on Quaternary Stratigraphy (SQS) of the International Commission on Stratigraphy (ICS) to develop a formal stratigraphical subdivision of the Holocene, with three new stages/ages, two underpinned by Global Boundary Stratotype Sections and Points (GSSPs) in an ice core, and a third in a speleothem. These stages/ages are defined along with their equivalent subseries/subepochs. The new stages/ages are the Greenlandian with its GSSP in the Greenland NGRIP2 ice core and dated at 11,700 yr b2k (before 2000 CE); the NorthGrippian with its GSSP in the Greenland NGRIP1 ice core and dated to 8236 yr b2k; and the Meghalayan, with its GSSP in a speleothem from Mawmluh Cave, northeastern India, with a date of 4250 yr b2k. This subdivision was formally ratified by the Executive Committee of the International Union of Geological Sciences (IUGS) on 14th June 2018.non

    The Energy of Regular Black Hole in General Relativity Coupled to Nonlinear Electrodynamics

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    According to the Einstein, Weinberg, and M{\o}ller energy-momentum complexes, we evaluate the energy distribution of the singularity-free solution of the Einstein field equations coupled to a suitable nonlinear electrodynamics suggested by Ay\'{o}n-Beato and Garc\'{i}a. The results show that the energy associated with the definitions of Einstein and Weinberg are the same, but M{\o}ller not. Using the power series expansion, we find out that the first two terms in the expression are the same as the energy distributions of the Reissner-Nordstr\"{o}m solution, and the third term could be used to survey the factualness between numerous solutions of the Einstein field eqautions coupled to a nonlinear electrodynamics.Comment: 11 page

    A composite immune signature parallels disease progression across T1D subjects

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    At diagnosis, most people with type 1 diabetes (T1D) produce measurable levels of endogenous insulin, but the rate at which insulin secretion declines is heterogeneous. To explain this heterogeneity, we sought to identify a composite signature predictive of insulin secretion, using a collaborative assay evaluation and analysis pipeline that incorporated multiple cellular and serum measures reflecting beta cell health and immune system activity. The ability to predict decline in insulin secretion would be useful for patient stratification for clinical trial enrollment or therapeutic selection. Analytes from 12 qualified assays were measured in shared samples from subjects newly diagnosed with T1D. We developed a computational tool to identify a composite panel associated with decline in insulin secretion over 2 years after diagnosis. The tool employs multiple filtering steps to reduce data dimensionality, incorporates error-estimation techniques including cross-validation and sensitivity analysis, and is flexible to assay type, clinical outcome and disease setting. Using this novel analytical tool, we identified a panel of immune markers that, in combination, are highly associated with loss of insulin secretion. The methods used here represent a novel process for identifying combined immune signatures that predict outcomes relevant for complex and heterogeneous diseases like T1D

    Characterisation of redox states of metal-organic frameworks by growth on modified thin-film electrodes

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    The application of metal-organic framework (MOF) materials in electrochemical and electrochromic devices remain rare. One of the main reasons for this is the inability to readily access their detailed electrochemistry. The inherent insolubility of these materials does not allow interrogation by traditional solution-based electrochemical or spectroscopic methods. In this study, we report a straightforward alternative approach to the spectroelectrochemical study of MOFs. We have used two systems as exemplars in this study, MFM-186 and MFM-180. The method involves chemical modification of a working electrode to attach MOF materials without using corrosive reagents such as inorganic acids or bases which otherwise could limit their application in device development. MFM-186 demonstrates the formation of a stable radical species [MFM-186]●+ on electrochemical oxidation, and this has been characterised by electrochemical, spectroelectrochemical and EPR spectroscopic techniques coupled to DFT analysis
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