1,216 research outputs found

    Fiber-diffraction Interferometer using Coherent Fiber Optic Taper

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    We present a fiber-diffraction interferometer using a coherent fiber optic taper for optical testing in an uncontrolled environment. We use a coherent fiber optic taper and a single-mode fiber having thermally-expanded core. Part of the measurement wave coming from a test target is condensed through a fiber optic taper and spatially filtered from a single-mode fiber to be reference wave. Vibration of the cavity between the target and the interferometer probe is common to both reference and measurement waves, thus the interference fringe is stabilized in an optical way. Generation of the reference wave is stable even with the target movement. Focus shift of the input measurement wave is desensitized by a coherent fiber optic taper

    The impact of the home musical environment on infants' language development

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    There is strong evidence that musical engagement influences children’s language development but little research has been carried out on the relationship between the home musical environment and language development in infancy. The current study assessed musical exposure at home (including parental singing) and language development in 64 infants (8.5 - 18 months). Results showed that the home musical environment significantly predicted gesture development. For a subgroup of infants’ below 12 months, both parental singing and overall home musical environment score significantly predicted word comprehension. These findings represent the first demonstration that an enriched musical environment in infancy can promote development of communication skill

    Purification and identification of secernin, a novel cytosolic protein that regulates exocytosis in mast cells

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    After permeabilization with the pore-forming toxin streptolysin-O mast cells can be triggered to secrete by addition of both calcium and a GTP analogue. If stimulation is delayed after permeabilization, there is a progressive decrease in the extent of secretion upon stimulation, eventually leading to a complete loss of the secretory response. This loss of secretory response can be retarded by the addition of cytosol from other secretory tissues, demonstrating that the response is dependent on a number of cytosolic proteins. We have used this as the basis of a bioassay to purify Secernin 1, a novel 50-kDa cytosolic protein that appears to be involved in the regulation of exocytosis from peritoneal mast cells. Secernin 1 increases both the extent of secretion and increases the sensitivity of mast cells to stimulation with calcium

    Introduction

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    Modelling background charge rearrangements near single-electron transistors as a Poisson process

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    Background charge rearrangements in metallic single-electron transistors are modelled in two-level tunnelling systems as a Poisson process with a scale parameter as only variable. The model explains the recent observation of asymmetric Coulomb blockade peak spacing distributions in metallic single-electron transistors. From the scale parameter we estimate the average size of the tunnelling systems, their density of states, and the height of their energy barrier. We conclude that the observed background charge rearrangements predominantly take place in the substrate of the single-electron transistor.Comment: 7 pages, 2 eps figures, used epl.cls macro include

    SOOP Network Enhancement Report

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    Report on the network enhancement project, this will document (a) extension of network coverage to South Atlantic; (b) evaluation of improved EOV carbonate system; and (c) re-assessment of instrumentatio

    Transition from small to large world in growing networks

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    We examine the global organization of growing networks in which a new vertex is attached to already existing ones with a probability depending on their age. We find that the network is infinite- or finite-dimensional depending on whether the attachment probability decays slower or faster than (age)−1(age)^{-1}. The network becomes one-dimensional when the attachment probability decays faster than (age)−2(age)^{-2}. We describe structural characteristics of these phases and transitions between them.Comment: 5 page

    Two photon excitable graphene quantum dots for structured illumination microscopy and imaging application: lysosome specificity and tissue-dependent imaging

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    Two-photon active Graphene Quantum Dots (GQDs) are obtained from extracts of the neem root. These biocompatible GQDs are found to be suitable for structured illumination microscopy. Two-photon microscopy ensured lysosome specificity of GQDs in live cells and confocal luminescence microscopic studies showed tissue-dependent localization of GQDs in Zebrafis

    Addition-Deletion Networks

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    We study structural properties of growing networks where both addition and deletion of nodes are possible. Our model network evolves via two independent processes. With rate r, a node is added to the system and this node links to a randomly selected existing node. With rate 1, a randomly selected node is deleted, and its parent node inherits the links of its immediate descendants. We show that the in-component size distribution decays algebraically, c_k ~ k^{-beta}, as k-->infty. The exponent beta=2+1/(r-1) varies continuously with the addition rate r. Structural properties of the network including the height distribution, the diameter of the network, the average distance between two nodes, and the fraction of dangling nodes are also obtained analytically. Interestingly, the deletion process leads to a giant hub, a single node with a macroscopic degree whereas all other nodes have a microscopic degree.Comment: 8 pages, 5 figure
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