On the design of a real-time volume rendering engine

An architecture for a Real-Time Volume Rendering Engine (RT-VRE) is given, capable of computing 750 × 750 × 512 samples from a 3D dataset at a rate of 25 images per second. The RT-VRE uses for this purpose 64 dedicated rendering chips, cooperating with 16 RISC-processors. A plane interpolator circuit and a composition circuit, both capable to operate at very high speeds, have been designed for a 1.6 micron VLSI process. Both the interpolator and composition circuit are back from production. They have been tested and both complied with our specifications

Run-time mapping of applications to a heterogeneous reconfigurable tiled system on chip architecture

This work evaluates an algorithm that maps a number of communicating processes to a heterogeneous tiled system on chip (SoC) architecture at run-time. The mapping algorithm minimizes the total amount of energy consumption, while still providing an adequate quality of service (QoS). A realistic example is mapped using this algorithm

The Recent Cholera Outbreak in the South Mrican Gold Mining Industry

A large-scale cholera surveillance programme was introduced in South Africa in November 1973 as a result of the progressive southward spread of cholera in Africa. Moore's technique for the isolation of Salmonella paratyphi was modified for cholera detection. The method proved to be very sensitive and it was possible to detect Vibrio cholerae in main sewer lines after its casual and transient introduction by an unidentified carrier. Transmission occurred in the acc!im<:tisation centre, probably through the drinking of water contaminated after it had been drawn from the tap. Faecal contamination of the environment was demonstrated, and V. cho/erae was isolated from the floor, onto which it had been disseminated from the perianal region by means of profuse perspiration. Perpetuation of cholera was probably aided by a faecally contaminated air-humidifying water reservoir, the water of which experimentally allows survival and multiplication of V. cholerae for a week and longer. Prophylactic treatment of selected high-risk groups of people was administered in the form of doxycycline, which appeared to result in rapid termination of the epidemic. Mass vaccination of all mine personnel (20 000) was carried out to reduce the incidence of clinical cholera and the bacterial load

Education for All as praxis: consequences for the profession

In this paper we explore the concepts that form the framework for the differentresearch projects that are reported in this special issue. All projects were part ofthe international Pedagogy, Education and Praxis research network. The maingoal of this paper is to set the theoretical ‘mis-en-scène’ for the other papers inthe issue. First, based on literature, we explore different meanings of conceptssuch as ‘Education for All’, ‘social justice’, ‘praxis’ and ‘pedagogy’. Secondly,we explain why we rely on these concepts and, finally, we investigate the conse-quences of these decisions for the profession, including professionals in schoolsas well as in universities. Teaching and Teacher Learning (ICLON

Vancomycin Clearance in Obese Adults is not Predictive of Clearance in Obese Adolescents

Contradictory pharmacokinetic (PK) results have been observed between obese adults and obese adolescents, with absolute clearance (CL) reported to be either unaltered, lower, or higher in obese adolescents compared to obese adults. This study investigates the PK of vancomycin in adolescents and adults who are overweight or obese. Data from 125 overweight and obese adolescents (aged 10–18 years, weight 28.3–188 kg) and 81 overweight and obese adults (aged 29–88 years, weight 66.7–143 kg) were analysed using population PK modelling. In addition to age, sex, renal function estimates, and regular weight descriptors, we evaluated standard weight (WTstandard, defined as weight for length, age, and sex in adolescents and weight for length in adults) and excess weight (WTexcess, defined as total body weight (TBW) minus WTstandard) as covariates in order to distinguish between weight resulting from length versus weight resulting from obesity. Analyzing adolescents and adults together, vancomycin CL was found to increase with TBW and decrease with increasing age (p \u3c 0.001). A covariate analysis investigating adolescents and adults separately found that vancomycin CL increased with WTstandard in adolescents and adults, albeit with different functions, with adolescents having a higher CL per WTstandard than adults. Moreover, in this separate model, adolescent males had 21% higher CL than adolescent females of the same WTstandard, while in adults, CL decreased with increasing age (p \u3c 0.001). There are apparent differences in vancomycin CL in overweight and obese adults versus overweight and obese adolescents, implying that dosing of vancomycin cannot be directly extrapolated between these populations