230 research outputs found
Origin, evolution and dynamic context of a Neoglacial lateral-frontal moraine at Austre Lovénbreen, Svalbard
Moraines marking the Neoglacial limits in Svalbard are commonly ice cored. Investigating the nature of this relict ice is important because it can aid our understanding of former glacier dynamics. This paper examines the composition of the lateralâfrontal moraine associated with the Neoglacial limit at Austre LovĂ©nbreen and assesses the likely geomorphological evolution. The moraine was investigated using ground-penetrating radar (GPR), with context being provided by structural mapping of the glacier based on an oblique aerial image from 1936 and vertical aerial imagery from 2003. Multiple up-glacier dipping reflectors and syncline structures are found in the GPR surveys. The reflectors are most clearly defined in lateral positions, where the moraine is substantially composed of ice. The frontal area of the moraine is dominantly composed of debris. The core of the lateral part of the moraine is likely to consist of stacked sequences of basal ice that have been deformed by strong longitudinal compression. The long term preservation potential of the ice-dominated lateral moraine is negligible, whereas the preservation of the debris-dominated frontal moraine is high. A glacier surface bulge, identified on the 1936 aerial imagery, provides evidence that Austre LovĂ©nbreen has previously displayed surge activity, although it is highly unlikely to do so in the near future in its current state. This research shows the value of relict buried ice that is preserved in landforms to aiding our understanding of former glacier characteristics
The Herts and Minds study: feasibility of a randomised controlled trial of Mentalizationbased Treatment versus usual care to support the wellbeing of children in foster care
© The Author(s). 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.Background: There is a lack of well-designed randomized controlled trials (RCTs) to investigate the efficacy of psychological therapies for children in foster care with emotional and behavioural difficulties. Mentalization-based therapy (MBT) focuses on supporting the carer-child relationship by promoting reflective capacity. This study examined the feasibility and acceptability of an RCT of MBT, delivered in a family-format, for children who are in foster care in the UK. Method: Herts and Minds was a phase II, blinded feasibility RCT with follow-up of at 12 and 24 weeks post-randomisation. Participants were children (age 5-16) in foster care referred to a targeted mental health service, who had some level of difficulty as identified by the Strengths and Difficulties Questionnaire (SDQ). Aims were to assess: the feasibility of recruitment processes and study uptake; capacity to train mental health practitioners to deliver MBT to an acceptable level of treatment integrity; establish acceptability and credibility of MBT as an intervention for children in foster care; establish feasibility and acceptability to participants of conducting an RCT; and estimate the likely treatment efficacy effect size. Participants were randomly allocated to either MBT (n = 15) or Usual Clinical Care (UCC) (n = 21) individually or in sibling groups. A range of qualitative and quantitative data was gathered to assess feasibility. Results: Feasibility was established with regard to: capacity to recruit participants to a study; capacity to train mental health practitioners to deliver MBT to an acceptable level of treatment integrity; acceptability and credibility of MBT; and feasibility and acceptability to participants of conducting an RCT. A number of issues made it difficult to estimate a likely treatment efficacy effect size. Conclusion: With modifications, it is feasible to run an RCT of MBT for children in foster care. Both the therapy and research design were acceptable to participants, but modifications may be needed regarding both the timing of assessments and the identification of appropriate primary outcome measures. Given the lack of evidenced based therapies for this population, such a trial would be a significant contribution to the field. Findings may be useful for other groups planning clinical trials of psychological therapies for children in foster care. Trial registration: ISRCTN 90349442. The trial was retrospectively registered on 6 May 2016.Peer reviewedFinal Published versio
Evolution of high-Arctic glacial landforms during deglaciation
Glacial landsystems in the high-Arctic have been reported to undergo geomorphological transformation during deglaciation. This research evaluates moraine evolution over a decadal timescale at Midtre LovĂ©nbreen, Svalbard. This work is of interest because glacial landforms developed in Svalbard have been used as an analogue for landforms developed during Pleistocene mid-latitude glaciation. Ground penetrating radar was used to investigate the subsurface characteristics of moraines. To determine surface change, a LiDAR topographic data set (obtained 2003) and a UAV-derived (obtained 2014) digital surface model processed using structure-from-motion (SfM) are also compared. Evaluation of these data sets together enables subsurface character and landform response to climatic amelioration to be linked. Ground penetrating radar evidence shows that the moraine substrate at Midtre LovĂ©nbreen includes ice-rich (radar velocities of 0.17âŻmâŻnsâ1) and debris-rich (radar velocities of 0.1â0.13âŻmâŻnsâ1) zones. The ice-rich zones are demonstrated to exhibit relatively high rates of surface change (mean thresholded rate of â4.39âŻm over the 11-year observation period). However, the debris-rich zones show a relatively low rate of surface change (mean thresholded rate of â0.98âŻm over the 11-year observation period), and the morphology of the debris-rich landforms appear stable over the observation period. A complex response of proglacial landforms to climatic warming is shown to occur within and between glacier forelands as indicated by spatially variable surface lowering rates. Landform response is controlled by the ice-debris balance of the moraine substrate, along with the topographic context (such as the influence of meltwater). Site-specific characteristics such as surface debris thickness and glaciofluvial drainage are, therefore, argued to be a highly important control on surface evolution in ice-cored terrain, resulting in a diverse response of high-Arctic glacial landsystems to climatic amelioration. These results highlight that care is needed when assessing the long-term preservation potential of contemporary landforms at high-Arctic glaciers. A better understanding of ice-cored terrain facilitates the development of appropriate age and climatic interpretations that can be obtained from palaeo ice-marginal landsystems
A qualitative analysis of goals set by foster carers seeking support for their childâs emotional well-being
The needs of foster carers are complex as children in their care often present with complex emotional and behavioural difficulties. Previous studies have examined foster carersâ perceptions of the unmet needs of the children in their care but there is a lack of knowledge regarding carersâ own goals when seeking professional help. The present study seeks to fill this gap by examining the goals that carers who are looking after children with emotional and/or behavioural difficulties set at the start of an intervention, the Reflective Fostering Programme, designed to support them. Twenty-six foster carers were asked to complete a Goal-Based Outcome Measure (GBOM) before starting the programme. Qualitative content analysis revealed five main categories of goals. Three were child focused (childâs relationships, challenging behaviours and emotions) and two were foster carer focused (personal goals and goals related to participating in the programme). By understanding the types of goals meaningful to foster carers, interventions can be developed to better target their specific needs and allow outcome measures to be more closely aligned to their goals. Results are discussed in terms of implications for the development and evaluation of interventions to support foster carers and the children they look after
Analysis of 'hummocky moraine' using Structure-from-Motion photogrammetry
This study presents results of a high-resolution topographic survey of the proglacial area of Austre Lovénbreen, Svalbard.
Structure-from-Motion (SfM) was used to generate a digital elevation model (DEM) of the proglacial zone from aerial imagery.
This DEM is used to explore the topography of a zone of hummocky moraine within the glacierâs Neoglacial limit. The origin
of hummocky moraine has proven controversial, but detailed morphological studies can contribute to a better understanding
of how these features form, and the extent to which they may be preserved in the palaeo-glaciological record, including
within northwest Britain. In cross-profile, hummocky moraine is characterised by a sequence of asymmetrical ridges, with
longer, low angle up-glacier faces, and shorter, steeper down-glacier faces. This profile is interpreted to represent a sequence of
ridges stacked-up against a bedrock riegel and reverse bedslope. Whilst the origin of these features is uncertain, the enhanced
compression associated with glacier flow against a bedrock riegel, possibly during a glacier surge, may have been sufficient
to have generated debris-rich englacial thrusts that subsequently melted-out to form the observed hummocky moraine. The
significance of this research highlights ongoing studies aimed at understanding the origin and palaeo-glaciological significance
of hummocky moraine in northwest Britain
Psychotherapy Dropout: Using the Adolescent Psychotherapy Q-Set to Explore the Early In-Session Process of Short-Term Psychodynamic Psychotherapy
Research suggests that short-term psychodynamic psychotherapy (STPP) is an effective treatment for depression in adolescence, yet treatment dropout is a major concern and what leads to dropout is poorly understood. Whilst studies have begun to explore the role of patient and therapist variables, there is a dearth of research on the actual therapy process and investigation of the interaction between patient and therapist. This study aims to address this paucity through the utilisation of the Adolescent Psychotherapy Q-set (APQ) to examine the early treatment period. The sample includes 69 adolescents aged 16â18 years with major depressive disorder receiving STPP as part of the First Experimental Study of Transference Workâin Teenagers (FEST-IT) trial. Of these, 21 were identified as dropouts and were compared to completers on pre-treatment patient characteristics, symptomatology, functioning, and working alliance. APQ ratings available for an early session from 16 of these drop out cases were analysed to explore the patient-therapist interaction structure. Results from the Q-factor analysis revealed three distinct interaction structures that explained 54.3% of the total variance. The first described a process of mutual trust and collaboration, the second was characterised by patient resistance and emotional detachment, the third by a mismatch and incongruence between therapist and adolescent. Comparison between the three revealed interesting differences which taken together provide further evidence that the reasons why adolescents drop out of therapy vary and are multidimensional in nature
The role of glacier mice in the invertebrate colonisation of glacial surfaces: the moss balls of the Falljökull, Iceland
Glacier surfaces have a surprisingly complex ecology. Cryoconite holes contain diverse invertebrate communities while other invertebrates, such as Collembola often graze on algae and windblown dead organic on the glacier surface. Glacier mice (ovoid unattached moss balls) occur on some glaciers worldwide. Studies of these glacier mice have concentrated on their occurrence and mode of formation. There are no reports of the invertebrate communities. But, such glacier mice may provide a suitable favourable habitat and refuge for a variety of invertebrate groups to colonise the glacier surface. Here we describe the invertebrate fauna of the glacier mice (moss balls) of the Falljökull, Iceland. The glacier mice were composed of Racomitrium sp. and varied in size from 8.0 to 10.0 cm in length. All glacier mice studied contained invertebrates. Two species of Collembola were present. Pseudisotoma sensibilis (Tullberg, 1876) was numerically dominant with between 12 and 73 individuals per glacier mouse while Desoria olivacea (Tullberg, 1871) occurred but in far lower numbers. Tardigrada and Nematoda had mean densities of approximately 200 and 1,000 respectively. No Acari, Arachnida or Enchytraeidae were observed which may be related to the difficulty these groups have in colonizing the glacier mice. We suggest that glacier mice provide an unusual environmentally ameliorated microhabitat for an invertebrate community dwelling on a glacial surface. The glacier mice thereby enable an invertebrate fauna to colonise an otherwise largely inhospitable location with implications for carbon flow in the system
Enteric-coated sodium bicarbonate supplementation improves high-intensity cycling performance in trained cyclists
Charge ordered ferromagnetic phase in La0.5Ca0.5MnO3
Mixed valent manganites are noted for their unusual magnetic,electronic and
structural phase transitions. The La1-xCaxMnO3 phase diagram shows that below
transition temperatures in the range 100-260 K, compounds with 0.2 < x < 0.5
are ferromagnetic and metallic whereas those with 0.5 < x < 0.9 are
antiferromagnetic and charge ordered. In a narrow region around x = 0.5, these
totally dissimilar states are thought to coexist. Uehara et al. have shown that
charge order and charge disorder can coexist in the related compound
La0.25Pr0.375Ca0.375MnO3. Here, we present electron microscopy data for
La0.5Ca0.5MnO3 that sheds light on the distribution of coexisting phases and
uncovers a novel and unexpected phase. Using electron holography and Fresnel
imaging, we find micron sized ferromagnetic regions spanning several grains
coexisting with similar sized regions with no local magnetisation. Holography
shows that the ferromagnetic regions have a local magnetisation of 3.4 +- 0.2
mB/Mn (the spin aligned value is 3.5 mB/Mn). We use electron diffraction and
dark field imaging to show that charge order exists in regions with no net
magnetisation and, surprisingly, can also occur in ferromagnetic regions.Comment: 5 pages of pdf with 2 figures include
Genomic Sequencing and Comparative Analysis of Epstein-Barr Virus Genome Isolated from Primary Nasopharyngeal Carcinoma Biopsy
Whether certain Epstein-Barr virus (EBV) strains are associated with pathogenesis of nasopharyngeal carcinoma (NPC) is still an unresolved question. In the present study, EBV genome contained in a primary NPC tumor biopsy was amplified by Polymerase Chain Reaction (PCR), and sequenced using next-generation (Illumina) and conventional dideoxy-DNA sequencing. The EBV genome, designated HKNPC1 (Genbank accession number JQ009376) is a type 1 EBV of approximately 171.5 kb. The virus appears to be a uniform strain in line with accepted monoclonal nature of EBV in NPC but is heterogeneous at 172 nucleotide positions. Phylogenetic analysis with the four published EBV strains, B95-8, AG876, GD1, and GD2, indicated HKNPC1 was more closely related to the Chinese NPC patient-derived strains, GD1 and GD2. HKNPC1 contains 1,589 single nucleotide variations (SNVs) and 132 insertions or deletions (indels) in comparison to the reference EBV sequence (accession number NC007605). When compared to AG876, a strain derived from Ghanaian Burkitt's lymphoma, we found 322 SNVs, of which 76 were non-synonymous SNVs and were shared amongst the Chinese GD1, GD2 and HKNPC1 isolates. We observed 88 non-synonymous SNVs shared only by HKNPC1 and GD2, the only other NPC tumor-derived strain reported thus far. Non-synonymous SNVs were mainly found in the latent, tegument and glycoprotein genes. The same point mutations were found in glycoprotein (BLLF1 and BALF4) genes of GD1, GD2 and HKNPC1 strains and might affect cell type specific binding. Variations in LMP1 and EBNA3B epitopes and mutations in Cp (11404 C>T) and Qp (50134 G>C) found in GD1, GD2 and HKNPC1 could potentially affect CD8+ T cell recognition and latent gene expression pattern in NPC, respectively. In conclusion, we showed that whole genome sequencing of EBV in NPC may facilitate discovery of previously unknown variations of pathogenic significance
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