Análise diagnóstica e prospectiva da cadeia produtiva de energia de biomassa de origem florestal.

bitstream/CNPF-2009-09/42554/1/Doc151.pdf1 CD-ROM

Seasonal variation in the incidence of deep vein thrombosis in patients with deficiency of protein C or protein S.

An attempt was made to identify circaseptanal or seasonal variation of deep vein thrombosis (DVT) in a population with protein C or protein S deficit. Forty-four patients with DVT and protein C or protein S deficit were studied for 1 year. A significant circannual rhythm was found for the total population that peaked during winter. There was also a significant falling circaseptanal rhythm on Fridays. These observations may optimize an adequate and precise anticoagulant therapy in patients witi protein C or protein S deficits

The Hubble Space Telescope UV Legacy Survey of Galactic Globular Clusters. XIII. ACS/WFC Parallel-Field Catalogues

As part of the Hubble Space Telescope UV Legacy Survey of Galactic Globular Clusters, 110 parallel fields were observed with the Wide Field Channel of the Advanced Camera for Surveys, in the outskirts of 48 globular clusters, plus the open cluster NGC 6791. Totalling about $0.3$ square degrees of observed sky, this is the largest homogeneous Hubble Space Telescope photometric survey of Galalctic globular clusters outskirts to date. In particular, two distinct pointings have been obtained for each target on average, all centred at about $6.5$ arcmin from the cluster centre, thus covering a mean area of about $23\,{\rm arcmin^{2}}$ for each globular cluster. For each field, at least one exposure in both F475W and F814W filters was collected. In this work, we publicly release the astrometric and photometric catalogues and the astrometrised atlases for each of these fields.Comment: 30 pages, 23 figures. Accepted by MNRA

Small inner marsh area delimitation using remote sensing spectral indexes and decision tree method in southern Brazil

Revista oficial de la Asociación Española de Teledetección[EN] Vast small inner marsh (SIM) areas have been lost in the past few decades through the conversion to agricultural, urban and industrial lands. The remaining marshes face several threats such as drainage for agriculture, construction of roads and port facilities, waste disposal, among others. This study integrates 17 remote sensing spectral indexes and decision tree (DT) method to map SIM areas using Sentinel 2A images from Summer and Winter seasons. Our results showed that remote sensing indexes, although not developed specifically for wetland delimitation, presented satisfactory results in order to classify these ecosystems. The indexes that showed to be more useful for marshes classification by DT techniques in the study area were NDTI, BI, NDPI and BI_2, with 25.9%, 17.7%, 11.1% and 0.8%, respectively. In general, the Proportion Correct (PC) found was 95.9% and 77.9% for the Summer and Winter images respectively. We hypothetize that this significant PC variation is related to the rice-planting period in the Summer and/or to the water level oscillation period in the Winter. For future studies, we recommend the use of active remote sensors (e.g., radar) and soil maps in addition to the remote sensing spectral indexes in order to obtain better results in the delimitation of small inner marsh areas.[ES] En las últimas décadas se han perdido grandes áreas de pequeñas marismas interiores (SIM) a través de la conversión a tierras agrícolas, urbanas e industriales. Las marismas restantes enfrentan varias amenazas, como el drenaje para la agricultura, la construcción de carreteras e instalaciones portuarias, la eliminación de residuos, entre otras. Este estudio integra 17 índices espectrales de teledetección y un método basado en árboles de decisión (DT) para cartografiar áreas de pequeñas marismas interiores utilizando imágenes del satélite Sentinel 2A de verano e invierno. Los resultados muestran que los índices de teledetección, aunque no han sido desarrollados específicamente para la delimitación de marismas, presentan resultados satisfactorios para clasificar estos ecosistemas. Los índices que demostraron ser más útiles para la clasificación de marismas mediante técnicas de DT en el área de estudio fueron el NDTI, BI, NDPI y BI_2, con 25.9%, 17.7%, 11.1% y 0.8%, respectivamente. En general, la proporción correcta encontrada fue de 95.9% y 77.9% para las imágenes de verano e invierno, respectivamente. Nuestra hipótesis es que esta variación significativa de la proporción correcta está relacionada con el período de siembra del arroz en verano y/o con el período de oscilación del nivel del agua en invierno. Para futuras investigaciones, recomendamos el uso de sensores remotos activos (por ejemplo, radar) y mapas de suelo además de los índices espectrales de teledetección para obtener mejores resultados en la delimitación de pequeñas áreas de marismas interiores.João Paulo Delapasse Simioni thanks the CAPES agency for providing a doctoral fellowship. The au-thors acknowledge the Center for Remote Sensing and Meteorology (CEPSRM) at the Federal University of Rio Grande do Sul (UFRGS) for the support provided for this research.Simioni, JPD.; Guasselli, LA.; Ruiz, LFC.; Nascimento, VF.; De Oliveira, G. (2018). Delimitación de pequeñas marismas interiores mediante índices espectrales y árboles de decisión en el sur de Brasil. Revista de Teledetección. (52):55-66. doi:10.4995/raet.2018.10366SWORD556652Artigas, F. J., Yang, J. 2006. Spectral discrimination of marsh vegetation types in the New Jersey Meadowlands, USA. 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Acta Scientiarum - Biological Sciences, 30(4), 403-409. https://doi.org/10.4025/actascibiolsci.v30i4.5870Kaplan, G., Avdan, U. 2017. Mapping and Monitoring Wetlands Using SENTINEL 2 Satellite Imagery. ISPRS Annals of Photogrammetry, Remote Sensing and Spatial Information Sciences, IV, 271-277. https:// doi.org/10.5194/isprs-annals-IV-4-W4-271-2017Kaplan, G., Avdan, U. 2017. Wetland Mapping Using Sentinel 1 SAR Data. In Suha Ozden, R. Cengiz Akbulak, Cuneyt Erenoglu, Oznur Karaca, Faize Saris, & Mustafa Avcioglu (Eds.), International Symposium on GIS Applications in Geography & Geosciences.Kaufman, Y., Tanre, D. 1992. 1992. Atmospherically resistant vegetation index (ARVI) for EOS-MODIS. IEEE Transactions on Geoscience and Remote Sensing, 30(2). https://doi.org/10.1109/36.134076Kulawardhana, R. W., Thenkabail, P. S., Vithanage, J., Biradar, C., Islam, M. A. a, Gunasinghe, S., Alankara, R. 2007. Evaluation of the wetland mapping methods using Landsat ETM+ and SRTM data. Journal of Spatial Hydrology, 7(2), 62-96. https://doi. org/10.1017/CBO9780511806049Lacaux, J. P., Tourre, Y. M., Vignolles, C., Ndione, J. A., Lafaye, M. 2007. Classification of ponds from highspatial resolution remote sensing: Application to Rift Valley Fever epidemics in Senegal. Remote Sensing of Environment, 106(1), 66-74. https://doi.org/10.1016/j. rse.2006.07.012Leite, M. G., Guasselli, L. A. 2013. Spatio-temporal dynamics of aquatic macrophytes in Banhado Grande, Gravataí River basin,. Para Onde!?, 7(1), 17-24.Liu, L., Liu, Y. H., Liu, C. X., Wang, Z., Dong, J., Zhu, G. F., Huang, X. 2013. Potential effect and accumulation of veterinary antibiotics in Phragmites australis under hydroponic conditions. Ecological Engineering, 53, 138-143. https://doi.org/10.1016/j. ecoleng.2012.12.033Mahdavi, S., Salehi, B., Amani, M., Granger, J. E., Brisco, B., Huang, W., Hanson, A. 2017. ObjectBased Classification of Wetlands in Newfoundland and Labrador Using Multi-Temporal PolSAR Data. Canadian Journal of Remote Sensing, 43(5), 432-450. https://doi.org/10.1080/07038992.2017.1342206Maltchik, L., Rolon, A. S., Guadagnin, D. L., Stenert, C. 2004. Wetlands of Rio Grande do Sul, Brazil: a classification with emphasis on plant communities. Acta Limnol. Bras, 16(2), 137-151.Mao, R., Ye, S.-Y., Zhang, X.-H. 2018. SoilAggregate-Associated Organic Carbon Along Vegetation Zones in Tidal Salt Marshes in the Liaohe Delta. CLEAN - Soil, Air, Water, 1-7. https://doi.org/10.1002/clen.201800049McFeeters, S. K. 1996. The use of the Normalized Difference Water Index (NDWI) in the delineation of open water features. International Journal of Remote Sensing, 17(7), 1425-1432. https://doi.org/10.1080/01431169608948714Mcowen, C. J., Weatherdon, L. V, Bochove, J.-W. Van, Sullivan, E., Blyth, S., Zockler, C., Fletcher, S. 2017. A global map of saltmarshes. Biodiversity Data Journal, 5(5), e11764. https://doi.org/10.3897/BDJ.5.e11764Miranda, C. de S., Paranho Filho, A. C., Pott, A. 2018. Changes in vegetation cover of the Pantanal wetland detected by vegetation index: a strategy for conservation. Biota Neotropica, 18(1), 1-6. https://doi.org/10.1590/1676-0611-bn-2016-0297Mondal, I., Bandyopadhyay, J. 2014. Coastal Wetland Modeling Using Geoinformatics Technology of Namkhana Island, South 24 Parganas, WB, India. Open Access Library Journal, 975, 1-17. https://doi.org/10.4236/oalib.1100975Nielsen, S. 1994. Geomorfologia da bacia do rio GravataíRS. In Bacia do rio Gravataí-RS: informações básicas para a gestão territorial (pp. 1-18). Porto Alegre: Proteger.Nunes da Cunha, C., Piedade, M. T. F., Junk, W. J. 2015. Classificação e Delineamento das Áreas Úmidas Brasileiras e de seus Macrohabitats. EdUFMT (Vol. 1). Cuiaba. https://doi.org/10.1017/CBO9781107415324.004Pearson, R. L., Miller, L. D. 1972. Remote Mapping of Standing Crop Biomass for Estimation of the Productivity of the Shortgrass Prairie. Remote Sensing of Environment, 8, 1355-1365.Pontius, R. 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Suppression of nitric oxide production in mouse macrophages by soybean flavonoids accumulated in response to nitroprusside and fungal elicitation

BACKGROUND: The anti-inflammatory properties of some flavonoids have been attributed to their ability to inhibit the production of NO by activated macrophages. Soybean cotyledons accumulate certain flavonoids following elicitation with an extract of the fungal pathogen Diaporthe phaseolorum f. sp. meridionalis (Dpm). Sodium nitroprusside (SNP), a nitric oxide donor, can substitute for Dpm in inducing flavonoid production. In this study, we investigated the effect of flavonoid-containing diffusates obtained from Dpm- and SNP-elicited soybean cotyledons on NO production by lipopolysaccharide (LPS)- and LPS plus interferon-γ (IFNγ)-activated murine macrophages. RESULTS: Significant inhibition of NO production, measured as nitrite formation, was observed when macrophages were activated in the presence of soybean diffusates from Dpm- or SNP-elicited cotyledons. This inhibition was dependent on the duration of exposure to the elicitor. Daidzein, genistein, luteolin and apigenin, the main flavonoids present in diffusates of elicited cotyledons, suppressed the NO production by LPS + IFNγ activated macrophages in a concentration-dependent manner, with IC(50 )values of 81.4 μM, 34.5 μM, 38.6 μM and 10.4 μM respectively. For macrophages activated with LPS alone, the IC(50 )values were 40.0 μM, 16.6 μM, 10.4 μM and 2.8 μM, respectively. Western blot analysis showed that iNOS expression was not affected by daidzein, was reduced by genistein, and was abolished by apigenin, luteolin and Dpm- and SNP-soybean diffusates at concentrations that significantly inhibited NO production by activated macrophages. CONCLUSIONS: These results suggest that the suppressive effect of flavonoids on iNOS expression could account for the potent inhibitory effect of Dpm- and SNP-diffusates on NO production by activated macrophages. Since the physiological concentration of flavonoids in plants is normally low, the treatment of soybean tissues with SNP may provide a simple method for substantially increasing the concentration of metabolites that are beneficial for the treatment of chronic inflammatory diseases associated with NO production

Concomitant homozygosity for the prothrombin gene variant with mild deficiency of antithrombin III in a patient with multiple hepatic infarctions: a case report

<p>Abstract</p> <p>Introduction</p> <p>Hereditary causes of visceral thrombosis or thrombosis should be sought among young patients. We present a case of a young man presenting with multiple hepatic infarctions resulting in portal hypertension due to homozygosity of the prothrombin gene mutation not previously described in literature.</p> <p>Case presentation</p> <p>A 42-year-old Caucasian man with a previous history of idiopathic deep vein thrombosis 11 years earlier presented with vague abdominal pains and mildly abnormal liver function tests. An ultrasound and computed tomography scan showed evidence of hepatic infarction and portal hypertension (splenic varices). A thrombophilia screen confirmed a homozygous mutation for the prothrombin gene mutation, with mildly reduced levels of anti-thrombin III (AT III). Subsequent testing of his father and brother revealed heterozygosity for the same gene mutation.</p> <p>Conclusion</p> <p>Hepatic infarction is unusual due to the rich dual arterial and venous blood supply to the liver. In the absence of an arterial or haemodynamic insult causing hepatic infarction, a thrombophilia should be considered. To our knowledge, this is the first reported case of a hepatic infarction due to homozygosity of the prothrombin gene mutation. It is unclear whether homozygotes have a higher risk of thrombosis than heterozygotes. In someone presenting with a first thrombosis with this mutation, the case for life-long anticoagulation is unclear, but it may be necessary to prevent a second and more severe second thrombotic event, as occurred in this case.</p

Neutralization of the neuromuscular activity of bothropstoxin-i, a myotoxin from Bothrops jararacussu snake venom, by a hydroalcoholic extract of Casearia sylvestris Sw. (guaçatonga)

Numerous plants are used as snakebite antidotes in Brazilian folk medicine, including Casearia sylvestris Swartz, popularly known as guaçatonga. In this study, we examined the action of a hydroalcoholic extract from C. sylvestris on the neuromuscular blockade caused by bothropstoxin-I (BthTX-I), a myotoxin from Bothrops jararacussu venom, in mouse isolated phrenic nerve-diaphragm (PND) preparations. Aqueous (8 and 12 mg/ml, n=4 and 5, respectively) and hydroalcoholic (12 mg/ml, n=12) extracts of the leaves of C. sylvestris caused facilitation in PND preparations followed by partial neuromuscular blockade. BthTX-I (20 µg/ml, n=4) caused 50% paralysis after 65±15 min (mean ± S.E.M). Preincubation (30 min at 37° C) of BthTX-I (20 µg/ml, n=4) with a concentration of the hydroalcoholic extract (4 mg/ml) that had no neuromuscular activity, such as the control (n=5), prevented the neuromuscular blockade caused by the toxin. This protection may be mediated by compounds such as flavonoids and phenols identified by thin-layer chromatography and colorimetric assays.465478Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP

Allergic diseases in the elderly: biological characteristics and main immunological and non-immunological mechanisms

Life expectancy and the number of elderly people are progressively increasing around the world. Together with other pathologies, allergic diseases also show an increasing incidence in geriatric age. This is partly due to the growing emphasis on a more accurate and careful diagnosis of the molecular mechanisms that do not allow to ignore the real pathogenesis of many symptoms until now unknown, and partly to the fact that the allergic people from 20 years ago represent the elderly population now. Moreover, environmental pollution predisposes to the onset of allergic asthma and dermatitis which are the result of internal pathologies more than the expression of allergic manifestations. At the same time the food contamination permits the onset of allergic diseases related to food allergy. In this review we provide the state of the art on the physiological changes in the elderly responsible for allergic diseases, their biological characteristics and the major immunological and extra immunological mechanisms. Much emphasis is given to the management of several diseases in the elderly, including anaphylactic reactions. Moreover, some new features are discussed, such as management of asthma with the support of physical activity and the use of the AIT as prevention of respiratory diseases and for the purpose of a real and long lasting benefit. The mechanisms of adverse reactions to drugs are also discussed, due to their frequency in this age, especially in polytherapy regimens. Study of the modifications of the immune system is also of great importance, as regards to the distribution of the lymphocytes and also the presence of a chronic inflammatory disease related to the production of cytokines, especially in prevision of all the possible therapies to be adopted to allow an active and healthy agin