17,731 research outputs found
A performance comparison of the contiguous allocation strategies in 3D mesh connected multicomputers
The performance of contiguous allocation strategies can be significantly affected by the distribution of job execution times. In this paper, the performance of the existing contiguous allocation strategies for 3D mesh multicomputers is re-visited in the context of heavy-tailed distributions (e.g., a Bounded Pareto distribution). The strategies are evaluated and compared using simulation experiments for both First-Come-First-Served (FCFS) and Shortest-Service-Demand (SSD) scheduling strategies under a variety of system loads and system sizes. The results show that the performance of the allocation strategies degrades considerably when job execution times follow a heavy-tailed distribution. Moreover, SSD copes much better than FCFS scheduling strategy in the presence of heavy-tailed job execution times. The results also show that the strategies that depend on a list of allocated sub-meshes for both allocation and deallocation have lower allocation overhead and deliver good system performance in terms of average turnaround time and mean system utilization
Structural and functional conservation of key domains in InsP3 and ryanodine receptors.
Inositol-1,4,5-trisphosphate receptors (InsP(3)Rs) and ryanodine receptors (RyRs) are tetrameric intracellular Ca(2+) channels. In each of these receptor families, the pore, which is formed by carboxy-terminal transmembrane domains, is regulated by signals that are detected by large cytosolic structures. InsP(3)R gating is initiated by InsP(3) binding to the InsP(3)-binding core (IBC, residues 224-604 of InsP(3)R1) and it requires the suppressor domain (SD, residues 1-223 of InsP(3)R1). Here we present structures of the amino-terminal region (NT, residues 1-604) of rat InsP(3)R1 with (3.6 Å) and without (3.0 Å) InsP(3) bound. The arrangement of the three NT domains, SD, IBC-β and IBC-α, identifies two discrete interfaces (α and β) between the IBC and SD. Similar interfaces occur between equivalent domains (A, B and C) in RyR1 (ref. 9). The orientations of the three domains when docked into a tetrameric structure of InsP(3)R and of the ABC domains docked into RyR are remarkably similar. The importance of the α-interface for activation of InsP(3)R and RyR is confirmed by mutagenesis and, for RyR, by disease-causing mutations. Binding of InsP(3) causes partial closure of the clam-like IBC, disrupting the β-interface and pulling the SD towards the IBC. This reorients an exposed SD loop ('hotspot' (HS) loop) that is essential for InsP(3)R activation. The loop is conserved in RyR and includes mutations that are associated with malignant hyperthermia and central core disease. The HS loop interacts with an adjacent NT, suggesting that activation re-arranges inter-subunit interactions. The A domain of RyR functionally replaced the SD in full-length InsP(3)R, and an InsP(3)R in which its C-terminal transmembrane region was replaced by that from RyR1 was gated by InsP(3) and blocked by ryanodine. Activation mechanisms are conserved between InsP(3)R and RyR. Allosteric modulation of two similar domain interfaces within an N-terminal subunit reorients the first domain (SD or A domain), allowing it, through interactions of the second domain of an adjacent subunit (IBC-β or B domain), to gate the pore
20 K superconductivity in heavily electron doped surface layer of FeSe bulk crystal
A superconducting transition temperature Tc as high as 100 K was recently
discovered in 1 monolayer (1ML) FeSe grown on SrTiO3 (STO). The discovery
immediately ignited efforts to identify the mechanism for the dramatically
enhanced Tc from its bulk value of 7 K. Currently, there are two main views on
the origin of the enhanced Tc; in the first view, the enhancement comes from an
interfacial effect while in the other it is from excess electrons with strong
correlation strength. The issue is controversial and there are evidences that
support each view. Finding the origin of the Tc enhancement could be the key to
achieving even higher Tc and to identifying the microscopic mechanism for the
superconductivity in iron-based materials. Here, we report the observation of
20 K superconductivity in the electron doped surface layer of FeSe. The
electronic state of the surface layer possesses all the key spectroscopic
aspects of the 1ML FeSe on STO. Without any interface effect, the surface layer
state is found to have a moderate Tc of 20 K with a smaller gap opening of 4
meV. Our results clearly show that excess electrons with strong correlation
strength alone cannot induce the maximum Tc, which in turn strongly suggests
need for an interfacial effect to reach the enhanced Tc found in 1ML FeSe/STO.Comment: 5 pages, 4 figure
High-Efficiency Resonant RF Spin Rotator with Broad Phase Space Acceptance for Pulsed Polarized Cold Neutron Beams
We have developed a radio-frequency resonant spin rotator to reverse the
neutron polarization in a 9.5 cm x 9.5 cm pulsed cold neutron beam with high
efficiency over a broad cold neutron energy range. The effect of the spin
reversal by the rotator on the neutron beam phase space is compared
qualitatively to RF neutron spin flippers based on adiabatic fast passage. The
spin rotator does not change the kinetic energy of the neutrons and leaves the
neutron beam phase space unchanged to high precision. We discuss the design of
the spin rotator and describe two types of transmission-based neutron spin-flip
efficiency measurements where the neutron beam was both polarized and analyzed
by optically-polarized 3He neutron spin filters. The efficiency of the spin
rotator was measured to be 98.0+/-0.8% on resonance for neutron energies from
3.3 to 18.4 meV over the full phase space of the beam. As an example of the
application of this device to an experiment we describe the integration of the
RF spin rotator into an apparatus to search for the small parity-violating
asymmetry A_gamma in polarized cold neutron capture on para-hydrogen by the
NPDGamma collaboration at LANSCE
Trends in Cancer-Center Spending on Advertising in the United States, 2005 to 2014
In the United States, cancer centers commonly advertise clinical services directly to the public. Potential benefits of such advertising include informing patients about available treatments and reducing the stigma of cancer.1, 2 Potential risks include misleading vulnerable patients and creating false hopes, increasing demand for unnecessary tests and treatments, adversely affecting existing clinician-patient relationships, and increasing healthcare costs.3, 4 Understanding trends in the advertising spending of cancer centers and the characteristics of the centers that spend the most can inform the debate about the impact of these advertisements. Our hypothesis was that advertising spending has increased and that spending is concentrated among for-profit cancer centers
Vehicular traffic flow at an intersection with the possibility of turning
We have developed a Nagel-Schreckenberg cellular automata model for
describing of vehicular traffic flow at a single intersection. A set of traffic
lights operating in fixed-time scheme controls the traffic flow. Open boundary
condition is applied to the streets each of which conduct a uni-directional
flow. Streets are single-lane and cars can turn upon reaching to the
intersection with prescribed probabilities. Extensive Monte Carlo simulations
are carried out to find the model flow characteristics. In particular, we
investigate the flows dependence on the signalisation parameters, turning
probabilities and input rates. It is shown that for each set of parameters,
there exist a plateau region inside which the total outflow from the
intersection remains almost constant. We also compute total waiting time of
vehicles per cycle behind red lights for various control parameters.Comment: 8 pages, 17 eps figures, Late
Growth Dynamics of Photoinduced Domains in Two-Dimensional Charge-Ordered Conductors Depending on Stabilization Mechanisms
Photoinduced melting of horizontal-stripe charge orders in
quasi-two-dimensional organic conductors
\theta-(BEDT-TTF)2RbZn(SCN)4[BEDT-TTF=bis(ethylenedithio)tetrathiafulvalene]
and
\alpha-(BEDT-TTF)2I3 is investigated theoretically. By numerically solving
the time-dependent Schr\"odinger equation, we study the photoinduced dynamics
in extended Peierls-Hubbard models on anisotropic triangular lattices within
the
Hartree-Fock approximation. The melting of the charge order needs more energy
for \theta-(BEDT-TTF)2RbZn(SCN)4 than for \alpha-(BEDT-TTF)2I3, which is a
consequence of the larger stabilization energy in \theta-(BEDT-TTF)2RbZn(SCN)4.
After local photoexcitation in the charge ordered states, the growth of a
photoinduced domain shows anisotropy. In \theta-(BEDT-TTF)2RbZn(SCN)4, the
domain hardly expands to the direction perpendicular to the horizontal-stripes.
This is because all the molecules on the hole-rich stripe are rotated in one
direction and those on the hole-poor stripe in the other direction. They
modulate horizontally connected transfer integrals homogeneously, stabilizing
the charge order stripe by stripe. In \alpha-(BEDT-TTF)2I3, lattice distortions
locally stabilize the charge order so that it is easily weakened by local
photoexcitation. The photoinduced domain indeed expands in the plane. These
results are consistent with recent observation by femtosecond reflection
spectroscopy.Comment: 9 pages, 8 figures, to appear in J. Phys. Soc. Jpn. Vol. 79 (2010)
No.
Finite-Temperature Properties across the Charge Ordering Transition -- Combined Bosonization, Renormalization Group, and Numerical Methods
We theoretically describe the charge ordering (CO) metal-insulator transition
based on a quasi-one-dimensional extended Hubbard model, and investigate the
finite temperature () properties across the transition temperature, . In order to calculate dependence of physical quantities such as the
spin susceptibility and the electrical resistivity, both above and below
, a theoretical scheme is developed which combines analytical
methods with numerical calculations. We take advantage of the renormalization
group equations derived from the effective bosonized Hamiltonian, where Lanczos
exact diagonalization data are chosen as initial parameters, while the CO order
parameter at finite- is determined by quantum Monte Carlo simulations. The
results show that the spin susceptibility does not show a steep singularity at
, and it slightly increases compared to the case without CO because
of the suppression of the spin velocity. In contrast, the resistivity exhibits
a sudden increase at , below which a characteristic dependence
is observed. We also compare our results with experiments on molecular
conductors as well as transition metal oxides showing CO.Comment: 9 pages, 8 figure
Tricritical Behavior in Charge-Order System
Tricritical point in charge-order systems and its criticality are studied for
a microscopic model by using the mean-field approximation and exchange Monte
Carlo method in the classical limit as well as by using the Hartree-Fock
approximation for the quantum model. We study the extended Hubbard model and
show that the tricritical point emerges as an endpoint of the first-order
transition line between the disordered phase and the charge-ordered phase at
finite temperatures. Strong divergences of several fluctuations at zero
wavenumber are found and analyzed around the tricritical point. Especially, the
charge susceptibility chi_c and the susceptibility of the next-nearest-neighbor
correlation chi_R are shown to diverge and their critical exponents are derived
to be the same as the criticality of the susceptibility of the double occupancy
chi_D0. The singularity of conductivity at the tricritical point is clarified.
We show that the singularity of the conductivity sigma is governed by that of
the carrier density and is given as
|sigma-sigma_c|=|g-g_c|^{p_t}Alog{|g-g_{c}|}+B), where g is the effective
interaction of the Hubbard model, sigma_c g_c represents the critical
conductivity(interaction) and A and B are constants, respectively. Here, in the
canonical ensemble, we obtain p_t=2beta_t=1/2 at the tricritical point. We also
show that p_t changes into p_{t}'=2beta=1 at the tricritical point in the
grand-canonical ensemble when the tricritical point in the canonical ensemble
is involved within the phase separation region. The results are compared with
available experimental results of organic conductor (DI-DCNQI)2Ag.Comment: 20 pages, 32 figures, to appear in J. Phys. Soc. Jpn.
Vol.75(2006)No.
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