10 research outputs found

    \u3cb\u3eBook Review:\u3c/b\u3e \u3cem\u3eIntegrative learning: Mapping the terrain\u3c/em\u3e by Mary Taylor Huber and Pat Hutchings (Association of American Colleges and Universities, 2004)

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    Excerpt: In my own past public school teaching experiences, interdisciplinary learning, thematic instruction, and inquiry approaches all provided ways for students to mesh ideas across disciplines and sign systems with a complex gelling of ideas and knowledge building. Taking these ideas another step further, Integrative Learning: Mapping the Terrain offers detailed suggestions for how integrated knowledge building could look in the college or university setting. Mary Taylor Huber and Pat Hutchings are scholars at The Carnegie Foundation for the Advancement of Teaching. In this work, they offer a plausible and viable argument for college and university faculties who believe integrative learning is an important consideration for the complex curricular changes higher education faces in the coming century

    Reading and critiquing : an analysis of talk about strong books for girls.

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    In exploring what makes strong books for girls, these authors begin by looking at their critical conversations with each other

    Finishing the euchromatic sequence of the human genome

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    The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

    Book Review: Integrative learning: Mapping the terrain by Mary Taylor Huber and Pat Hutchings (Association of American Colleges and Universities, 2004)

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    Excerpt: In my own past public school teaching experiences, interdisciplinary learning, thematic instruction, and inquiry approaches all provided ways for students to mesh ideas across disciplines and sign systems with a complex gelling of ideas and knowledge building. Taking these ideas another step further, Integrative Learning: Mapping the Terrain offers detailed suggestions for how integrated knowledge building could look in the college or university setting. Mary Taylor Huber and Pat Hutchings are scholars at The Carnegie Foundation for the Advancement of Teaching. In this work, they offer a plausible and viable argument for college and university faculties who believe integrative learning is an important consideration for the complex curricular changes higher education faces in the coming century

    Renita Schmidt and Kathryn Whitmore interview

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    Webcast file name: schmidtandwhitmore_nov9_2010Date: November 9, 2010Voice of Literacy host, Dr. Betsy Baker, interviews Dr. Kathryn Whitmore, Coordinator, Language, Literacy and Culture Doctoral Program at the University of Iowa and Dr. Renita Schmidt, Assistant Professor of Education, Furman, University

    Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques

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    A safe and effective vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may be required to end the coronavirus disease 2019 (COVID-19) pandemic1–8. For global deployment and pandemic control, a vaccine that requires only a single immunization would be optimal. Here we show the immunogenicity and protective efficacy of a single dose of adenovirus serotype 26 (Ad26) vector-based vaccines expressing the SARS-CoV-2 spike (S) protein in non-human primates. Fifty-two rhesus macaques (Macaca mulatta) were immunized with Ad26 vectors that encoded S variants or sham control, and then challenged with SARS-CoV-2 by the intranasal and intratracheal routes9,10. The optimal Ad26 vaccine induced robust neutralizing antibody responses and provided complete or near-complete protection in bronchoalveolar lavage and nasal swabs after SARS-CoV-2 challenge. Titres of vaccine-elicited neutralizing antibodies correlated with protective efficacy, suggesting an immune correlate of protection. These data demonstrate robust single-shot vaccine protection against SARS-CoV-2 in non-human primates. The optimal Ad26 vector-based vaccine for SARS-CoV-2, termed Ad26.COV2.S, is currently being evaluated in clinical trials
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