20 research outputs found

    Inclusão, democracia e novo-desenvolvimentismo : um balanço histórico

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    Este trabalho analisa o processo do desenvolvimentismo brasileiro compreendido entre a fase clássica dos anos 1950 até a perspectiva atual do novo-desenvolvimentismo, privilegiando o papel e a função desempenhadas pelo tema da democracia e da inclusão distributiva em cada arranjo. Na primeira seção, analisa-se a constelação semântica que envolve os termos progresso e desenvolvimento, procurando separá-los do processo/projeto denominado desenvolvimentismo. Na segunda seção, discutem-se as fases e características centrais do velho e do novo-desenvolvimentismo brasileiro e a perspectiva de sua subdivisão em três ondas históricas, separadas pelo aspecto político democrático e pelo tema da redistribuição. Por último, apresentam-se algumas considerações sobre o novo-desenvolvimentismo em seu arranjo democrático-inclusivo.This paper analyzes the process of the Brazilian developmentalism between the classical phase of the 1950s to the current perspective of new developmentalism, emphasizing the role and function played by the theme of democracy and distributive inclusion in every arrangement. In the first section, it is analyzed the semantic constellation involving the terms progress and development, seeking to separate them from the process / project called developmentalism. In the second section, it is discussed the phases and the central features of the old and the new Brazilian developmentalism and the prospect of their subdivision into three historical waves, separated by the political democratic aspect and by the theme of redistribution. Finally it presents some considerations about the new developmentalism in its democratic-inclusive arrangement

    Polymorphisms In The Il1a And Il1b Genes Are Not Associated With Susceptibility To Chronic Periodontitis In A Brazilian Population

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    The aim of this study was to investigate the association between polymorphisms in the IL-1a and IL-1b genes and severity of chronic periodontitis in Brazilians. 113 non-smoking subjects over 25 years (mean age 41.6) were divided according to the severity level of periodontal disease: 44 healthy individuals (control group), 31 subjects with moderate and 38 with severe periodontitis. DNA was obtained from epithelial cells through a mouthwash with 3 % glucose and scraping of oral mucosa. The samples were analyzed for IL-1a (- 889) and IL-1b (+3953) polymorphisms using PCR-RFLP. The significance of the differences in the frequencies of the polymorphisms in the control and groups with periodontitis was assessed by Chisquare test (p<0.05). No significant differences in the allele and genotype frequencies were found among the groups. It was concluded that neither polymorphisms IL-1a (-889) and IL-1b (+3953) nor the composite genotype were associated with the severity of chronic periodontal disease in the study population.27348-35

    Microbial Diversity Similarities in Periodontal Pockets and Atheromatous Plaques of Cardiovascular Disease Patients

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    <div><p>Background and Objective</p><p>The immune and infectious alterations occurring in periodontitis have been shown to alter the development and severity of cardiovascular disease. One of these relationships is the translocation of oral bacteria to atheroma plaques, thereby promoting plaque development. Thus, the aim of this study was to assess, by 16s cloning and sequencing, the microbial diversity of the subgingival environment and atheroma plaques of patients concomitantly suffering from periodontitis and obstructive coronary artery atherosclerosis (OCAA).</p><p>Methods</p><p>Subgingival biofilm and coronary balloons used in percutaneous transluminal coronary angioplasty were collected from 18 subjects presenting with generalized moderate to severe periodontitis and OCAA. DNA was extracted and the gene 16S was amplified, cloned and sequenced.</p><p>Results</p><p>Significant differences in microbial diversity were observed between both environments. While subgingival samples mostly contained the phylum <i>Firmicutes</i>, in coronary balloons, <i>Proteobacteria</i> (p<0.05) was predominant. In addition, the most commonly detected genera in coronary balloons were <i>Acinetobacter, Alloprevotella, Pseudomonas, Enterobacter, Sphingomonas</i> and <i>Moraxella</i>, while in subgingival samples <i>Porphyromonas, Filifactor, Veillonella, Aggregatibacter</i> and <i>Treponema</i> (p<0.05) were found. Interestingly, 17 identical phylotypes were found in atheroma and subgingival samples, indicating possible bacterial translocation between periodontal pockets and coronary arteries.</p><p>Conclusion</p><p>Periodontal pockets and atheromatous plaques of cardiovascular disease patients can present similarities in the microbial diversity.</p></div

    Demographic data of population.

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    <p><i>SD- Standard deviation;</i></p><p><i>*HbA1c<7%;</i></p>#<p><i>Arterial Pressure >140/80 mmHg;</i></p><p>Demographic data of population.</p

    Distribution (%total clones and number of common phylotypes) regarding Phylo and Culture Status (%) in periodontal pocket and Coronary balloon.

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    <p><i>*indicate statistically difference (Chi-square test, p<0.05).</i></p><p>Distribution (%total clones and number of common phylotypes) regarding Phylo and Culture Status (%) in periodontal pocket and Coronary balloon.</p
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