Evolution of the physical properties of dust and cometary dust activity from 67P/Churyumov-Gerasimenko measured in situ by Rosetta/COSIMA

The Cometary Secondary Ion Mass Analyzer (COSIMA) collects dust particles in the coma of 67P/Churyumov-Gerasimenko, images them with a resolution of 14 mu m x 14 mu m, and measures their composition via time-of-flight secondary ion mass spectrometry. The particles are collected on targets exposed to the cometary flux for periods ranging from several hours to a week. Images are acquired with the internal camera, the COSISCOPE, before and after each exposure period. This paper focuses on the evolution of the dust flux and of the size distribution of the particles derived from the COSISCOPE images during the two years of the mission. The dust flux reaches its maximum at perihelion. We suggest that the delay of 20 d between the activity measured by COSIMA and the gas activity measured by the other instruments on Rosetta is caused by the presence of a volatile-poor dust layer on the nucleus that is removed around perihelion, uncovering volatile-rich layers that then become active. The difference in morphology between the northern and southern hemispheres observed by OSIRIS, the south being more sintered, is also recorded in the COSIMA data by a change in the size distribution during the southern summer, as the large porous aggregates disappear from the COSIMA collection. The properties of the particles collected during an outburst in early September 2016 indicate that these particles were ejected by a violent event and might originate from regions of low tensile strength

SERENA:Particle Instrument Suite for Determining the Sun-Mercury Interaction from BepiColombo

International audienceThe ESA-JAXA BepiColombo mission to Mercury will provide simultaneous measurements from two spacecraft, offering an unprecedented opportunity to investigate magnetospheric and exospheric particle dynamics at Mercury as well as their interactions with solar wind, solar radiation, and interplanetary dust. The particle instrument suite SERENA (Search for Exospheric Refilling and Emitted Natural Abundances) is flying in space on-board the BepiColombo Mercury Planetary Orbiter (MPO) and is the only instrument for ion and neutral particle detection aboard the MPO. It comprises four independent sensors: ELENA for neutral particle flow detection, Strofio for neutral gas detection, PICAM for planetary ions observations, and MIPA, mostly for solar wind ion measurements. SERENA is managed by a System Control Unit located inside the ELENA box. In the present paper the scientific goals of this suite are described, and then the four units are detailed, as well as their major features and calibration results. Finally, the SERENA operational activities are shown during the orbital path around Mercury, with also some reference to the activities planned during the long cruise phase

Correction to: SERENA: Particle Instrument Suite for Determining the Sun-Mercury Interaction from BepiColombo

International audienc

The disruption of proteostasis in neurodegenerative diseases

Cells count on surveillance systems to monitor and protect the cellular proteome which, besides being highly heterogeneous, is constantly being challenged by intrinsic and environmental factors. In this context, the proteostasis network (PN) is essential to achieve a stable and functional proteome. Disruption of the PN is associated with aging and can lead to and/or potentiate the occurrence of many neurodegenerative diseases (ND). This not only emphasizes the importance of the PN in health span and aging but also how its modulation can be a potential target for intervention and treatment of human diseases.info:eu-repo/semantics/publishedVersio

Tracking data highlight the importance of human-induced mortality for large migratory birds at a flyway scale

Human-induced direct mortality affects huge numbers of birds each year, threatening hundreds of species worldwide. Tracking technologies can be an important tool to investigate temporal and spatial patterns of bird mortality as well as their drivers. We compiled 1704 mortality records from tracking studies across the African-Eurasian flyway for 45 species, including raptors, storks, and cranes, covering the period from 2003 to 2021. Our results show a higher frequency of human-induced causes of mortality than natural causes across taxonomic groups, geographical areas, and age classes. Moreover, we found that the frequency of human-induced mortality remained stable over the study period. From the human-induced mortality events with a known cause (n = 637), three main causes were identified: electrocution (40.5 %), illegal killing (21.7 %), and poisoning (16.3 %). Additionally, combined energy infrastructure-related mortality (i.e., electrocution, power line collision, and wind-farm collision) represented 49 % of all human-induced mortality events. Using a random forest model, the main predictors of human-induced mortality were found to be taxonomic group, geographic location (latitude and longitude), and human footprint index value at the location of mortality. Despite conservation efforts, human drivers of bird mortality in the African-Eurasian flyway do not appear to have declined over the last 15 years for the studied group of species. Results suggest that stronger conservation actions to address these threats across the flyway can reduce their impacts on species. In particular, projected future development of energy infrastructure is a representative example where application of planning, operation, and mitigation measures can enhance bird conservation

Optical properties of cometary particles collected by COSIMA: Assessing the differences between microscopic and macroscopic scales

International audienceThe COSIMA mass spectrometer on-board Rosetta was equipped with an optical microscope, Cosiscope, which identified several 10,000 cometary particles collected on targets exposed during the orbital phase around the nucleus of comet 67P Churyumov-Gerasimenko. The median value of reflectance factors evaluated from Cosiscope images for large collected particles (~10.5% (Langevin et al., 2017), lies above the range of reflectance observed by the OSIRIS camera at a similar wavelength (5-7%, (Fornasier et al., 2015), but at much larger scales (a few 10 cm instead of a few 10 μm). In order to better understand this discrepancy, the assumptions underlying the derivation of reflectance factors have been reassessed using laboratory measurements of COSIMA targets and analogs of cometary particles. The approach of Langevin et al. is validated, but we consider that the uncertainty on reflectance factors was conservative. The reflectance factors are likely to lie in the lower half of the previously estimated range, which reduces (but does not eliminate) the discrepancy with OSIRIS albedos. The remaining discrepancy can be attributed primarily to the difference in scale (factor 10,000 in pixel size between COSIMA and OSIRIS)

Temperature-Dependent Influence of FliA Overexpression on PHL628 E. coli Biofilm Growth and Composition

Biofilm growth and survival pose a problem in both medical and industrial fields. Bacteria in biofilms are more tolerant to antibiotic treatment due to the inability of antibiotics to permeate to the bottom layers of cells in a biofilm and the creation of altered microenvironments of bacteria deep within the biofilm. Despite the abundance of information we have about E. coli biofilm growth and maturation, we are still learning how manipulating different signaling pathways influences the formation and fitness of biofilm. Understanding the impact of signaling pathways on biofilm formation may narrow the search for novel small molecule inhibitors or activators that affect biofilm production and stability. Here, we study the influence of the minor sigma transcription factor FliA (RpoF, sigma-28), which controls late-stage flagellar assembly and chemotaxis, on biofilm production and composition at various temperatures in the E. coli strain PHL628, which abundantly produces the extracellular structural protein curli. We examined FliA\u27s influence on external cellular structures like curli and flagella and the biomolecular composition of the biofilm\u27s extracellular polymeric substance (EPS) using biochemical assays, immunoblotting, and confocal laser scanning microscopy (CLSM). At 37 degrees C, FliA overexpression results in the dramatic growth of biofilm in polystyrene plates and more modest yet significant biofilm growth on silica slides. We observed no significant differences in curli concentration and carbohydrate concentration in the EPS with FliA overexpression. Still, we did see significant changes in the abundance of EPS protein using CLSM at higher growth temperatures. We also noticed increased flagellin concentration, a major structural protein in flagella, occurred with FliA overexpression, specifically in planktonic cultures. These experiments have aided in narrowing our focus to FliA\u27s role in changing the protein composition of the EPS, which we will examine in future endeavors

Electronic Polarization Effects upon Charge Injection in Oligoacene Molecular Crystals: Description via a Polarizable Force Field

Understanding the nature and magnitude of the electronic polarization due to the presence of a charge carrier in organic molecular solids is of fundamental importance in the description of charge-carrier transport. We present an approach to study these effects based on a polarizable force field that accounts for charge, dipole, quadrupole, and induced-dipole interactions. To demonstrate its general applicability, the method is applied to the oligoacene crystal series (naphthalene through pentacene) and perfluorinated derivatives of naphthalene and pentacene. Very good qualitative agreement with experimental results is achieved in terms of both the magnitude and asymmetry of the polarization as a function of the sign of the injected charge, with improved quantitative agreement versus previous theoretical assessments