Influence of music therapy on coping skills and anger management in forensic psychiatric patients: An exploratory study

The effect of music therapy on anger management and coping skills is an innovative subject in the field of forensic psychiatry. This study explores the following research question: Can music therapy treatment contribute to positive changes in coping skills, anger management, and dysfunctional behavior of forensic psychiatric patients? To investigate this question, first a literature review is offered on music therapy and anger management in forensic psychiatry. Then, an explorative study is presented. In the study, a pre- and post-test design was used with a random assignment of patients to either treatment or control condition. Fourteen participants’ complete datasets were collected. All participants received “treatment as usual.” Nine of the participants received a standardized, music therapy anger management program; the five controls received, unplanned, an aggression management program. Results suggested that anger management skills improved for all participants. The improvement of positive coping skills and diminishing of avoidance as a coping skill were measured to show greater changes in music therapy participants. When controlling for the exact number of treatment hours, the outcomes suggested that music therapy might accelerate the process of behavioral changes

Senescence and costs of reproduction in the life history of a small precocial species

Trillmich F, Geißler E, Günther A. Senescence and costs of reproduction in the life history of a small precocial species. Ecology and Evolution. 2019;9(12):7069-7079.Species following a fast life history are expected to express fitness costs mainly as increased mortality, while slow-lived species should suffer fertility costs. Because observational studies have limited power to disentangle intrinsic and extrinsic factors influencing senescence, we manipulated reproductive effort experimentally in the cavy (Cavia aperea) which produces extremely precocial young. We created two experimental groups: One was allowed continuous reproduction (CR) and the other intermittent reproduction (IR) by removing males at regular intervals. We predicted that the CR females should senesce (and die) earlier and produce either fewer and/or smaller, slower growing offspring per litter than those of the IR group. CR females had 16% more litters during three years than IR females. CR females increased mass and body condition more steeply and both remained higher until the experiment ended. Female survival showed no group difference. Reproductive senescence in litter size, litter mass, and reproductive effort (litter mass/maternal mass) began after about 600 days and was slightly stronger in CR than IR females. Litter size, litter mass, and offspring survival declined with maternal age and were influenced by seasonality. IR females decreased reproductive effort less during cold seasons and only at higher age than CR females. Nevertheless, offspring winter mortality was higher in IR females. Our results show small costs of reproduction despite high reproductive effort, suggesting that under ad libitum food conditions costs depend largely on internal regulation of allocation decisions

A typology of community flood resilience

Flood risk is increasing worldwide and there is a growing need to better understand the co-benefits of investments in disaster resilience. Utilizing a multinational community flood resilience dataset, this paper takes a systems approach to understanding community-level flood resilience. Using a cluster analysis and bivariate correlation methods, we develop a typology of community flood resilience capacity based on community characteristics and five capitals (human, financial, natural, physical, and social). Our results reinforce the importance of context-specific policymaking and give recommendations of four distinct clusters to investigate the relationship between flood resilience and prevailing development conditions. We especially find that communities with higher interactions between their capital capacities tend to have higher flood resilience levels. Additionally, there are indications that stronger interactions between community capacities can help to induce multiple co-benefits when investing in disaster resilience. Our results also have important policy implications on the individual community level. For example, based on our results, we suggest that communities with lower flood resilience capacities and interactions can best build resilience on leveraging their relatively higher human capital capacities to strengthen the financial and social capitals. Negative effects might happen for urban communities when co-benefits of natural and physical capital are not fully integrated. The highest flood resilience capacity is found in communities with a well-balanced household income distribution which is likely a contributing factor to the importance of financial capital for this cluster. Our results emphasize the importance of an integrative approach to management when implementing systematic flood disaster resilience metrics and development measures

Fiscal resilience challenged

The GAR Risk Atlas contributes to unveiling the hidden risk in national economies and their urban centres. Building on a multi-year effort by a consortium of leading scientific institutions coordinated by UNISDR, it provides a global vision of where and how disaster risk can undermine development. It estimates the probability of future disaster losses in the built environment for five major hazards (earthquakes, tsunamis, riverine floods, and tropical cyclones - winds and storm surge) and for every country and territory in the world and represents the results using robust risk metrics such as Average Annual Loss (AAL) and Probable Maximum Loss (PML). The GAR Risk Atlas (special report of the GAR series) presents the fully updated results of the global risk assessment in a visually appealing and innovative manner

Upregulation of Claudin-4, CAIX and GLUT-1 in distant breast cancer metastases

Background: Several studies have shown that the immunophenotype of distant breast cancer metastases may differ significantly from that of the primary tumor, especially with regard to differences in the level of hormone receptor protein expression, a process known as receptor conversion. This study aimed to compare expression levels of several membrane proteins between primary breast tumors and their corresponding distant metastases in view of their potential applicability for molecular imaging and drug targeting. Methods: Expression of Claudin-4, EGFR, CAIX, GLUT-1 and IGF1R was assessed by immunohistochemistry on tissue microarrays composed of 97 paired primary breast tumors and their distant (non-bone) metastases. Results: In both the primary cancers and the metastases, Claudin-4 was most frequently expressed, followed by GLUT-1, CAIX and EGFR. From primary breast cancers to their distant metastases there was positive to negative conversion, e. g. protein expression in the primary tumor with no expression in its paired metastasis, in 6%, 19%, 12%, 38%, and 0% for Claudin-4 (n.s), GLUT-1 (n.s), CAIX (n.s), EGFR (n.s) and IGF1R (n.s) respectively. Negative to positive conversion was seen in 65%, 47%, 43%, 9% and 0% of cases for Claudin-4 (p = 0.049), GLUT-1 (p = 0.024), CAIX (p = 0.002), EGFR (n.s.) and IGF1R (n.s.) respectively. Negative to positive conversion of Claudin-4 in the metastasis was significantly associated with tumor size (p = 0.015), negative to positive conversion of EGFR with negative PR status (p = 0.046) and high MAI (p = 0.047) and GLUT-1 negative to positive conversion with (neo)adjuvant chemotherapy (p = 0.039) and time to metastasis formation (p = 0.034). CAIX and GLUT-1 expression in the primary tumor were significantly associated with high MAI (p = 0.008 and p = 0.038 respectively). Conclusion: Claudin-4 is frequently expressed in primary breast cancers but especially in their metastases and is thereby an attractive membrane bound molecular imaging and drug target. Conversion in expression of the studied proteins from the primary tumor to metastases was fairly frequent, except for IGF1R, implying that the expression status of metastases cannot always be reliably predicted from the primary tumor, thereby necessitating biopsy for reliable assessmen

Return to work experiences of patients treated with stem cell transplantation for a hematologic malignancy

Purpose This qualitative study aimed to identify hematopoietic stem cell transplantation (HSCT) survivors’ (1) work perceptions; (2) barriers to and facilitators of return to work (RTW); and (3) possible solutions to improve RTW. Method Fifteen patients treated with HSCT 1–5 years ago participated in face-to-face semi-structured interviews. Interviews were analyzed following the steps of thematic content analyses. Results RTW was often characterized as a complex and prolonged trajectory, and it was frequently incomplete in working hours, tasks, and/or responsibilities. Work perceptions varied between patients; most valued work as positive, but some also reported a decline in work capacity and/or in importance. Perceived barriers included the duration and side effects of cancer treatment, the presence of comorbidity and poor health before diagnosis, having difficulties commuting and doing household tasks. Perceived facilitators were financial incentives, keeping in touch with the workplace, support of other patients and family, and looking after one’s health. Proposed solutions to improve RTW included discussing RTW at the hospital, enhanced employer support, improved accessibility of rehabilitation programs, and more information about the consequences of being sick-listed. Conclusions Many HSCT survivors value work as important and they are motivated to RTW. Insight in work perceptions, RTW barriers, and solutions might help researchers, healthcare professionals, and employers to develop and/or tailor individualized multidisciplinary care to facilitate RTW

Standardized disaster and climate resilience grading: A global scale empirical analysis of community flood resilience

Suitable and standardized indicators to track progress in disaster and climate resilience are increasingly considered a key requirement for successfully informing efforts towards effective disaster risk reduction and climate adaptation. Standardized measures of resilience which can be used across different geographical and socioeconomic contexts are however sparse. We present and analyze a standardized community resilience measurement framework for flooding. The corresponding measurement tool is modelled based on and adapted from a so-called ‘technical risk grading’ approach as used in the insurance sector. The grading approach of indicators is based on a two-step process: (i) raw data is collected, and (ii) experts grade the indicators, called sources of resilience, based on this data. We test this approach using approximately 1.25 million datapoints collected across more than 118 communities in nine countries. The quantitative analysis is complemented by content analysis to validate the results from a qualitative perspective. We find that some indicators can more easily be graded by looking at raw data alone, while others require a stronger application of expert judgement. We summarize the reasons for this through six key messages. One major finding is that resilience grades related to subjective characteristics such as ability, feel, and trust are far more dependent on expert judgment than on the actual raw data collected. Additionally, the need for expert judgement further increases if graders must extrapolate the whole community picture from limited raw data. Our findings regarding the role of data and grade specifications can inform ways forward for better, more efficient and increasingly robust standardized assessment of resilience. This should help to build global standardized and comparable, yet locally contextualized, baseline estimates of the many facets of resilience in order to track progress over time on disaster and climate resilience and inform the implementation of the Paris Agreement, Sendai Framework, and the Sustainable Development Goals

Return to work experiences of patients treated with stem cell transplantation for a hematologic malignancy

Purpose This qualitative study aimed to identify hematopoietic stem cell transplantation (HSCT) survivors’ (1) work perceptions; (2) barriers to and facilitators of return to work (RTW); and (3) possible solutions to improve RTW. Method Fifteen patients treated with HSCT 1–5 years ago participated in face-to-face semi-structured interviews. Interviews were analyzed following the steps of thematic content analyses. Results RTW was often characterized as a complex and prolonged trajectory, and it was frequently incomplete in working hours, tasks, and/or responsibilities. Work perceptions varied between patients; most valued work as positive, but some also reported a decline in work capacity and/or in importance. Perceived barriers included the duration and side effects of cancer treatment, the presence of comorbidity and poor health before diagnosis, having difficulties commuting and doing household tasks. Perceived facilitators were financial incentives, keeping in touch with the workplace, support of other patients and family, and looking after one’s health. Proposed solutions to improve RTW included discussing RTW at the hospital, enhanced employer support, improved accessibility of rehabilitation programs, and more information about the consequences of being sick-listed. Conclusions Many HSCT survivors value work as important and they are motivated to RTW. Insight in work perceptions, RTW barriers, and solutions might help researchers, healthcare professionals, and employers to develop and/or tailor individualized multidisciplinary care to facilitate RTW