2,546 research outputs found

    An Empirical Study on Dependence Clusters for Effort-Aware Fault-Proneness Prediction

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    A dependence cluster is a set of mutually inter-dependent program elements. Prior studies have found that large dependence clusters are prevalent in software systems. It has been suggested that dependence clusters have potentially harmful effects on software quality. However, little empirical evidence has been provided to support this claim. The study presented in this paper investigates the relationship between dependence clusters and software quality at the function-level with a focus on effort-aware fault-proneness prediction. The investigation first analyzes whether or not larger dependence clusters tend to be more fault-prone. Second, it investigates whether the proportion of faulty functions inside dependence clusters is significantly different from the proportion of faulty functions outside dependence clusters. Third, it examines whether or not functions inside dependence clusters playing a more important role than others are more fault-prone. Finally, based on two groups of functions (i.e., functions inside and outside dependence clusters), the investigation considers a segmented fault-proneness prediction model. Our experimental results, based on five well-known open-source systems, show that (1) larger dependence clusters tend to be more fault-prone; (2) the proportion of faulty functions inside dependence clusters is significantly larger than the proportion of faulty functions outside dependence clusters; (3) functions inside dependence clusters that play more important roles are more fault-prone; (4) our segmented prediction model can significantly improve the effectiveness of effort-aware fault-proneness prediction in both ranking and classification scenarios. These findings help us better understand how dependence clusters influence software quality

    The Candida Genome Database (CGD), a community resource for Candida albicans gene and protein information

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    The Candida Genome Database (CGD) is a new database that contains genomic information about the opportunistic fungal pathogen Candida albicans. CGD is a public resource for the research community that is interested in the molecular biology of this fungus. CGD curators are in the process of combing the scientific literature to collect all C.albicans gene names and aliases; to assign gene ontology terms that describe the molecular function, biological process, and subcellular localization of each gene product; to annotate mutant phenotypes; and to summarize the function and biological context of each gene product in free-text description lines. CGD also provides community resources, including a reservation system for gene names and a colleague registry through which Candida researchers can share contact information and research interests. CGD is publicly funded (by NIH grant R01 DE15873-01 from the NIDCR) and is freely available at http://www.candidagenome.org/

    Sequence resources at the Candida Genome Database

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    The Candida Genome Database (CGD, ) contains a curated collection of genomic information and community resources for researchers who are interested in the molecular biology of the opportunistic pathogen Candida albicans. With the recent release of a new assembly of the C.albicans genome, Assembly 20, C.albicans genomics has entered a new era. Although the C.albicans genome assembly continues to undergo refinement, multiple assemblies and gene nomenclatures will remain in widespread use by the research community. CGD has now taken on the responsibility of maintaining the most up-to-date version of the genome sequence by providing the data from this new assembly alongside the data from the previous assemblies, as well as any future corrections and refinements. In this database update, we describe the sequence information available for C.albicans, the sequence information contained in CGD, and the tools for sequence retrieval, analysis and comparison that CGD provides. CGD is freely accessible at and CGD curators may be contacted by email at [email protected]

    From 'River Cottage' to 'Chicken Run': Hugh Fearnley-Whttingstall and the class politics of ethical consumption

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    Lifestyle television provides a key site through which to explore the dilemmas of ethical consumption, as the genre shifts to consider the ethics of different consumption practices and taste cultures. UK television cook Hugh Fearnley-Whittingstall's TV programmes offer fertile ground not only for thinking about television personalities as lifestyle experts and moral entrepreneurs, but also for thinking about how the meanings and uses of their television image are inflected by genre. In this article we explore how the shift from the lifestyled downshifting narrative of the River Cottage series to the 'campaigning culinary documentary' Hugh's Chicken Run exposes issues of celebrity, class and ethics. While both series are concerned with ethical consumption, they work in different ways to reveal a distinction between 'ethical' and 'unethical' consumption practices and positions - positions that are inevitably classed

    The Candida genome database incorporates multiple Candida species: multispecies search and analysis tools with curated gene and protein information for Candida albicans and Candida glabrata

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    The Candida Genome Database (CGD, http://www.candidagenome.org/) is an internet-based resource that provides centralized access to genomic sequence data and manually curated functional information about genes and proteins of the fungal pathogen Candida albicans and other Candida species. As the scope of Candida research, and the number of sequenced strains and related species, has grown in recent years, the need for expanded genomic resources has also grown. To answer this need, CGD has expanded beyond storing data solely for C. albicans, now integrating data from multiple species. Herein we describe the incorporation of this multispecies information, which includes curated gene information and the reference sequence for C. glabrata, as well as orthology relationships that interconnect Locus Summary pages, allowing easy navigation between genes of C. albicans and C. glabrata. These orthology relationships are also used to predict GO annotations of their products. We have also added protein information pages that display domains, structural information and physicochemical properties; bibliographic pages highlighting important topic areas in Candida biology; and a laboratory strain lineage page that describes the lineage of commonly used laboratory strains. All of these data are freely available at http://www.candidagenome.org/. We welcome feedback from the research community at [email protected]

    New tools at the Candida Genome Database: biochemical pathways and full-text literature search

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    The Candida Genome Database (CGD, http://www.candidagenome.org/) provides online access to genomic sequence data and manually curated functional information about genes and proteins of the human pathogen Candida albicans. Herein, we describe two recently added features, Candida Biochemical Pathways and the Textpresso full-text literature search tool. The Biochemical Pathways tool provides visualization of metabolic pathways and analysis tools that facilitate interpretation of experimental data, including results of large-scale experiments, in the context of Candida metabolism. Textpresso for Candida allows searching through the full-text of Candida-specific literature, including clinical and epidemiological studies

    A Unified Model of Exclusive ρ0\rho^0, ϕ\phi and \jpsi Electroproduction

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    A two-component model is developed for diffractive electroproduction of ρ0\rho^0, ϕ\phi and \jpsi, based on non-perturbative and perturbative two-gluon exchange. This provides a common kinematical structure for non-perturbative and perturbative effects, and allows the role of the vector-meson vertex functions to be explored independently of the production dynamics. A good global description of the vector-meson data is obtained.Comment: 30 pages, 35 figure

    Tackling alcoholism and domestic violence in fisheries - a new opportunity to improve wellbeing for the most vulnerable people in global fisheries

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    The UN Sustainable Development Goals (SDGs) principle of ‘Leaving no one behind’ focusses global attention on the poorest and most vulnerable people. As different sectors grapple to engage meaningfully with this principle, we posit that greater consideration of social problems in fishing-dependent communities, such as alcoholism and domestic violence, presents an opportunity for fisheries governors to contribute to the SDGs mandate. We further argue that governing marine resources in ignorance of these problems can risk harming some of the most vulnerable people in fisheries. Using subjective wellbeing data from women living in two small-scale fishing communities in India and Sri Lanka, we demonstrate the prevalence and impact of alcoholism and domestic violence in fishing households. We further highlight how policies which restrict access to marine resources can undermine important coping strategies, in particular the ability of women to act as independent income-earners, exacerbating harm to already vulnerable women. A scoping review of the literature reveals that alcoholism and domestic violence are reported in certain fisheries around the world, and we theorise how this may relate to the nature of fishing life, and growing stresses regarding the future of fishing. Tackling the burdens of alcoholism and domestic violence in fisheries, where it is an issue, is an opportunity to improve wellbeing for men, women and their families. The paper concludes with tangible actions which marine resource governors could adopt to contribute to the ‘leave no one behind’ ethos
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