Fracture neck of femur treated with hemiarthroplasty and cannulated cancellous screw fixation: a comparative study

Background: Intracapsular fracture neck of femur has always presented great challenges to every Orthopaedic surgeons and it is remain a mystery whether to fix or to replace the fracture in the elderly. The aim of the study was to analyze the functional outcome of two widely used and accepted modalities of treatment in the age group 57-75 years, in Garden’s type I and II fractures, namely (a) cannulated cancellous screw fixation(internal fixation) and (b) modular bipolar prosthetic replacement of the femoral head (hemiarthroplasty).Methods: The total 110 patients were including in the study from age groups 57-75 (mean age 66). The Garden classification of fracture neck of femur was used to evaluate the displacement of femoral neck fractures. Only grade 1 and 2 was included in the study. 55 patients were included in each group A and B. Osteosynthesis (fracture fixation) was carried out by closed reduction and insertion of cannulated cancellous screw and in other group hemiarthroplasty was done.Results: In group A 55 patient with fracture neck of femur was treated by osteosynthesis i.e. fixation using 02 or 03 cannulated cancellous screw and in group B, 55 patients with fracture neck of femur was treated by modular bipolar replacement hemiarthroplasty. In Group A out of 55, 41 patients union was achieved between 08 to 14 months (mean 11.5 month), 09 patients developed non-union even after 16 months and 05 patients develop collapse of head with AVN with shortening at end of 02 year, however in Group B out of 55 patients 51 patients started walking after 2nd postoperative days, 02 patients developed infection, and 02 patients developed posterior dislocation.Conclusions: The fracture fixation may be tempting for fracture neck femur in age group 57-75 especially of Garden Type I but internal fixation put risk of non-union and AVN and second surgery may be required after few months or years  if patients survive. Based on results in our study we therefore can conclude that in Garden Type I and II femur neck fractures in the patients between 57-75 years of age, hemiarthroplasty is the better modality of treatment

Assessment of knowledge, practice and perception of menstruation among adult women in the reproductive age group, in Mangalore, India

Background: Women often lack knowledge regarding reproductive health including menstruation which can be due to socio-cultural barriers in which they grow up. The present study is aimed at assessing the level of knowledge regarding menstruation and hygienic practices and perceptions during menstruation.Methods: It was a cross sectional study, conducted among 110 adult women to assess their knowledge regarding menstruation, practices followed during menstruation and their perceptionof menstruation. The collected data was analyzed using SPSS version 17. 0. Chi square test was applied. P<0.05 was considered to be significant.Results: Only 52% of the study population has satisfactory knowledge regarding menstruation. Women between 15 to 20 years of age and those from the middle and higher socio-economic groups seem to possess maximum knowledge regarding menstruation. Women of the higher socio-economic group practice better sanitary measures during menstruation with 100% of them using pads, as compared to women of lower socio economic group who showed a trend of using cloth (87.5%). Women of the upper socio-economic class (42.78%) had better perception towards menstruation (p<0.05).Conclusions: It is very important that lower socio-economic group should be educated about the importance of maintaining hygiene during menstruation by proper health education and equip them with skills regarding safe and hygienic practices to prevent the risk for reproductive tract infections

Rehabilitation Exercise Repetition Segmentation and Counting using Skeletal Body Joints

Physical exercise is an essential component of rehabilitation programs that improve quality of life and reduce mortality and re-hospitalization rates. In AI-driven virtual rehabilitation programs, patients complete their exercises independently at home, while AI algorithms analyze the exercise data to provide feedback to patients and report their progress to clinicians. To analyze exercise data, the first step is to segment it into consecutive repetitions. There has been a significant amount of research performed on segmenting and counting the repetitive activities of healthy individuals using raw video data, which raises concerns regarding privacy and is computationally intensive. Previous research on patients' rehabilitation exercise segmentation relied on data collected by multiple wearable sensors, which are difficult to use at home by rehabilitation patients. Compared to healthy individuals, segmenting and counting exercise repetitions in patients is more challenging because of the irregular repetition duration and the variation between repetitions. This paper presents a novel approach for segmenting and counting the repetitions of rehabilitation exercises performed by patients, based on their skeletal body joints. Skeletal body joints can be acquired through depth cameras or computer vision techniques applied to RGB videos of patients. Various sequential neural networks are designed to analyze the sequences of skeletal body joints and perform repetition segmentation and counting. Extensive experiments on three publicly available rehabilitation exercise datasets, KIMORE, UI-PRMD, and IntelliRehabDS, demonstrate the superiority of the proposed method compared to previous methods. The proposed method enables accurate exercise analysis while preserving privacy, facilitating the effective delivery of virtual rehabilitation programs.Comment: 8 pages, 1 figure, 2 table

Evidence that endogenous formaldehyde produces immunogenic and atherogenic adduct epitopes

Endogenous formaldehyde is abundantly present in our bodies, at around 100 µM under normal conditions. While such high steady state levels of formaldehyde may be derived by enzymatic reactions including oxidative demethylation/deamination and myeloperoxidation, it is unclear whether endogenous formaldehyde can initiate and/or promote diseases in humans. Here, we show that fluorescent malondialdehyde-formaldehyde (M2FA)-lysine adducts are immunogenic without adjuvants in mice. Natural antibody titers against M2FA are elevated in atherosclerosis-prone mice. Staining with an antibody against M2FA demonstrated that M2FA is present in plaque found on the aortic valve of ApoE mice. To mimic inflammation during atherogenesis, human myeloperoxidase was incubated with glycine, H O , malondialdehyde, and a lysine analog in PBS at a physiological temperature, which resulted in M2FA generation. These results strongly suggest that the 1,4-dihydropyridine-type of lysine adducts observed in atherosclerosis lesions are likely produced by endogenous formaldehyde and malondialdehyde with lysine. These highly fluorescent M2FA adducts may play important roles in human inflammatory and degenerative diseases

Bactericidal activity of biosynthesized silver nanoparticles against human pathogenic bacteria

Green synthesis is an attractive and eco-friendly approach to generate potent antibacterial silver nanoparticles (Ag-NPs). Such particles have long been used to fight bacteria and represent a promising tool to overcome the emergence of antibiotic-resistant bacteria. In this study, green synthesis of Ag-NPs was attempted using plant extracts of Aloe vera, Portulaca oleracea and Cynodon dactylon. The identity and size of Ag-NPs was characterized by ultraviolet–visible spectrophotometer and scanning electron microscopy. Monodispersed Ag-NPs were produced with a range of different sizes based on the plant extract used. The bactericidal activity of Ag-NPs against a number of human pathogenic bacteria was determined using the disc diffusion method. The results showed that Gram positive bacteria were more susceptible than Gram negative ones to these antibacterial agents. The minimum inhibitory concentration was determined using the 96-well plate method. Finally, the mechanism by which Ag-NPs affect bacteria was investigated by SEM analysis. Bacteria treated with Ag-NPs were seen to undergo shrinkage and to lose their viability. This study provides evidence for a cheap and effective method for synthesizing potent bactericidal Ag-NPs and demonstrates their effectiveness against human pathogenic bacteria

Efficient Music Genre Classification for Real-Time Recommender Systems

All across the world, different people tend to listen to different music genres or subsets of genres that are similar to one another, according to their mood, the weather, or the occasion. At different times, people like to listen to distinct playlists, depending on circumstances such as the ones mentioned above. The main idea underlying the work in this thesis is to build and test a variety of ideas for automatically classifying music samples according to their genres, also known as Automatic Genre Recognition. Here, the main aim is to minimize the time for training the model and feature generation, as it is one of the main challenges in the field of Musical Information Retrieval systems. There have been numerous music recommendation systems based on music tagging by experts, and many other systems analyze other users’ behavior in order to generate recommendations. However, it would be useful to create a music recommendation system purely based on musical information retrieval. The algorithm devised in this thesis can be used for fast training while providing good classification performance. This is achieved by methods such as reducing the number of features required to train the model and minimizing the length of musical clips to be processed for generating those features. By classification and identifying the particular user’s behavior, this algorithm can generate a smart play list in shuffle mode that is likely to include songs that the user might like to listen to under the given circumstances

Design Of Trailer Structure For 12 Ton Payload Using Advanced Lightweight Material For Weight Reduction

&nbsp;Automotive structure is a vital component of every vehicle. It gives strength to the vehicle. Generally, all structures of truck-trailers which are commercial in nature have heavy weight because of that they have high fuel consumption and high emission which spoils the environment. In this research, an effort has been tried for selecting advanced lightweight material with high strength and low density for weight reduction. Finally, considerable weight reduction of 73.6% has been observed in the structure using advanced lightweight material. In addition, the fuel consumption and emissions of the vehicle decrease, which results to prevention of environment from pollution due to vehicles

Development and characterization of polyvinyl chloride-graphite membrane

196-200Graphite dispersed polyvinyl chloride membrane has been prepared by scalable solution blending technique in different compositions. The obtained composite has been characterized by infrared spectroscopy, X-ray diffraction and microscopic techniques. Results reveal the formation of intercalated composite with improved properties like solvent retaining capacity, porosity, swelling capacity, hardness, and tensile strength. Further, ion exchange ability has been determined by ASTM method and observed values are in range 10-1 (meq/g), which is comparable to industrial membrane and indicate its suitability for commercial application. Further, durability and mechanical strength is studied and compared with standard membrane, which reveals compatible to the commercially available membrane and confirms suitability for technical applications